Late and low compliance with hepatitis B serology screening among HIV-infected patients in a resource-limited setting: an issue to improve HIV care.

Abstract:

:Although hepatitis B serology screening has been recommended for HIV care, it has not been routinely performed. We aimed to assess compliance and timing of hepatitis B serology screening among HIV-infected patients in a resource-limited setting. A cross-sectional study was conducted in Thailand. Compliance, timing of hepatitis B serology screening, and factors associated with no HBsAg screening were determined. A total of 416 HIV-infected patients with 61% males were enrolled. Median (range) age at HIV diagnosis was 34 (16-75) years and 92% had heterosexual risk. Proportion of HBsAg screening and prevalence of positive HBsAg were 69.2% and 9.0%, respectively. There was no difference in the proportion of no HBsAg screening during the period 1990-2008 (p = 0.865). Proportion of anti-HBs and anti-HBc screening were 40.9% and 21.2%, respectively. HBsAg was screened before or on the day of anti-HIV testing in 9.1% and before antiretroviral therapy (ART) initiation in 27.2%. By Kaplan-Meier analysis, median time from anti-HIV testing to HBsAg screening was 55.9 (95% confidence interval [CI] 43.9, 68.3) months. By multivariate logistic regression, duration of HIV infection (odds ratio [OR] 1.14; 95% CI 1.07, 1.21), no anti-HBs screening (OR 1.65; 95% CI 1.4-2.63), and no anti-HCV screening (OR 2.60; 95% CI 1.62, 4.17) were associated with no HBsAg screening before ART initiation. In conclusion, compliance with hepatitis B serology screening was relatively low and late. Educational program regarding hepatitis B serology screening, identification of barriers, and interventions to eliminate these barriers in resource-limited settings are crucial to improve HIV care.

journal_name

Curr HIV Res

journal_title

Current HIV research

authors

Kiertiburanakul S,Chotiprasitsakul D,Atamasirikul K,Sungkanuparph S

doi

10.2174/157016211794582669

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

54-60

issue

1

eissn

1570-162X

issn

1873-4251

pii

ABS-121

journal_volume

9

pub_type

杂志文章
  • AIDS-related Kaposi's sarcoma: state of the art and therapeutic strategies.

    abstract::In the HAART era Kaposi's sarcoma (KS) remains the second most frequent tumor in HIV-infected patients worldwide, and it has become the most common cancer in Sub-Saharan Africa. In western countries the risk for KS in men having sex with men (MSM) is 5 to 10 times higher compared to other groups of individuals practic...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/157016209789973619

    authors: Martellotta F,Berretta M,Vaccher E,Schioppa O,Zanet E,Tirelli U

    更新日期:2009-11-01 00:00:00

  • Effects of vitamin A deficiency and opioids on parvalbumin + interneurons in the hippocampus of the HIV-1 transgenic rat.

    abstract::Opioid use in HIV infection has been associated with an increased frequency of neurological disease and cognitive impairment and vitamin A deficiency has been linked to progressive HIV disease in drug users. In this report the potential effects of these factors, alone and in combination, on gamma amino butyric acid (G...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016212802138715

    authors: Guo M,Bryant J,Sultana S,Jones O,Royal W 3rd

    更新日期:2012-07-01 00:00:00

  • Operational issues and barriers to implementation of prevention of mother-to-child transmission of HIV (PMTCT) interventions in Sub-Saharan Africa.

    abstract::Over the past 10 years substantial progress has been made in the implementation of prevention of mother-to-child transmission of HIV (PMTCT) interventions in Sub-Saharan Africa (SSA). In spite of this, new pediatric infections remain unacceptably high, contributing the majority (>90%) of the estimated 390,000 infectio...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/1570162x11311020007

    authors: Aizire J,Fowler MG,Coovadia HM

    更新日期:2013-03-01 00:00:00

  • Microarray Analysis Reveals Altered Lipid and Glucose Metabolism Genes in Differentiated, Ritonavir-Treated 3T3-L1 Adipocytes.

    abstract:OBJECTIVE:HIV lipodystrophy is characterised by abnormal adipose tissue distribution and metabolism, as a result of altered adipocyte function and gene expression. The protease inhibitor ritonavir is associated with the development of lipodystrophy. Quantifying changes in adipogenic gene expression in the presence of r...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162x13666150806110238

    authors: Loonam CR,O'Dell SD,Sharp PA,Mullen A

    更新日期:2016-01-01 00:00:00

  • Molecular Genetics and the Incidence of Transmitted Drug Resistance Among Pre-Treatment HIV-1 Infected Patients in the Eastern Cape, South Africa.

    abstract:BACKGROUND:Transmitted drug resistance (TDR) remains a significant threat to Human immunodeficiency virus (HIV) infected patients that are not exposed to antiretroviral treatment. Although, combined antiretroviral therapy (cART) has reduced deaths among infected individuals, emergence of drug resistance is gradually on...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162X17666191004093433

    authors: Digban TO,Iweriebor BC,Obi LC,Nwodo U,Okoh AI

    更新日期:2019-01-01 00:00:00

  • Virulence factors of Candida albicans isolates from the oral cavities of HIV-1-positive patients.

    abstract::The present study assessed the phenotypic aspects of oral-cavity Candida albicans isolates from 300 HIV-1- positive patients, relating the most commonly investigated virulence factors (enzyme typing and germ-tube formation) to the most common morphotypes. The samples were seeded into specific media for isolation and s...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162x113119990042

    authors: Menezes TO,Gillet LC,Menezes SA,Feitosa RN,Ishak MO,Ishak R,Marques-da-Silva SH,Vallinoto AC

    更新日期:2013-06-01 00:00:00

  • The Spontaneous Control of HIV Replication is Characterized by Decreased Pathological Changes in the Gut-associated Lymphoid Tissue.

    abstract:BACKGROUND:HIV infection induces alterations in the gut-associated lymphoid tissue (GALT) that constitutes the most important site for viral replication due to the extensive presence of effector memory T-cells. In the case of HIV-controllers, several studies have reported fewer peripheral alterations and conserved immu...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162X17666190130115113

    authors: Taborda NA,Correa LA,Feria MG,Rugeles MT

    更新日期:2018-01-01 00:00:00

  • Immunization for persons infected with human immunodeficiency virus.

    abstract::Immunization is an important measure to protect HIV-infected children and adults against certain vaccine preventable diseases. However, the antibody response, which is associated with the level of CD4+ T cell count, is frequently impaired in this group of patients. Certain vaccines enhance virus replication and transi...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/1570162043351084

    authors: Pancharoen C,Ananworanich J,Thisyakorn U

    更新日期:2004-10-01 00:00:00

  • Genotypic Methods for HIV Drug Resistance Monitoring: The Opportunities and Challenges Faced by China.

    abstract::AIDS is a globalized infectious disease. In 2014, UNAIDS launched a global project of "90-90-90" to end the HIV epidemic by 2030. The second and third 90 require 90% of HIV-1 infected individuals receiving antiretroviral therapy (ART) and durable virological suppression. However, wide use of ART will greatly increase ...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162X17666190927154110

    authors: Zuo L,Peng K,Hu Y,Xu Q

    更新日期:2019-01-01 00:00:00

  • Mother-to-child transmission of HIV infection and its prevention.

    abstract::An estimated 800,000 children acquired HIV-infection in 2002, most as a result of mother-to-child transmission (MTCT), and vertically-acquired HIV infection continues to be of major public health importance. Prevention of MTCT is possible with a combination of interventions including antiretroviral therapy (ART) (usua...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/1570162033485140

    authors: Thorne C,Newell ML

    更新日期:2003-10-01 00:00:00

  • Structural bases of the annealing of primer tRNA(3Lys) to the HIV-1 viral RNA.

    abstract::To promote the initiation of reverse transcription, the HIV-1 virus uses a host tRNA as a primer, tRNA(3Lys). The annealing of tRNA(3Lys) to the viral RNA requires the breaking of the 3D structure of the tRNA and RNA rearrangements, to form a stable initiation complex recognised by the reverse transcriptase. The annea...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/1570162053506919

    authors: Tisné C

    更新日期:2005-04-01 00:00:00

  • Prevalence of HIV-Seropositivity and Associated Impact on Mortality among Injured Patients from Low-and Middle-Income Countries: A Systematic Review and Meta-Analysis.

    abstract:BACKGROUND:Although HIV and injury contribute substantially to disease burdens in lowand middle-income countries (LMIC), their intersection is poorly characterized. OBJECTIVE:This systematic review assessed the prevalence and associated mortality impact of HIVseropositivity among injured patients in LMIC. METHODS:A s...

    journal_title:Current HIV research

    pub_type: 杂志文章,meta分析,评审

    doi:10.2174/1570162X15666170920112743

    authors: Aluisio AR,Rege S,Stewart BT,Kinuthia J,Levine AC,Mello MJ,Farquhar C

    更新日期:2017-11-23 00:00:00

  • Comparative Genetic Variability in HIV-1 Subtype C vpu Gene in Early Age Groups of Infants.

    abstract:OBJECTIVE:Identifying the genetic variability in vertically transmitted viruses in early infancy is important to understand the disease progression. Being important in HIV-1 disease pathogenesis, vpu gene, isolated from young infants was investigated to understand the viral characteristics. METHOD:Blood samples were o...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162X16666180219154601

    authors: Sharma U,Gupta P,Gupta S,Venkatesh S,Husain M

    更新日期:2018-01-01 00:00:00

  • Preventive antiretroviral therapy in non-thalassemia carrier infants exposed to mother-to-child transmission of HIV decreases cord and after delivery red blood production without altering the development of hemoglobin.

    abstract::Antiretroviral (ARV) prophylaxis for prevention of mother to child transmission (MTCT) of HIV could affect hemoglobin (Hb) development of infants. A cross-sectional descriptive study was conducted in 24 HIV-infected and 21 HIV-uninfected pregnancies. ARV drugs were administered to HIV-infected pregnancies at 21 weeks ...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162x12666140713170800

    authors: Pornprasert S,Wongnoi R,Oberdorfer P,Sirivatanapa P

    更新日期:2014-01-01 00:00:00

  • A digital signal processing-based bioinformatics approach to identifying the origins of HIV-1 non B subtypes infecting US Army personnel serving abroad.

    abstract::Two HIV-1 non B isolates, 98US_MSC5007 and 98US_MSC5016, which have been identified amongst the US Army personnel serving abroad, are known to have originated from other nations. Notwithstanding, they are categorized as American strains. This is because their countries of origin are unknown. American isolates are basi...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162x113119990046

    authors: Nwankwo N

    更新日期:2013-06-01 00:00:00

  • Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability.

    abstract::Previous studies have demonstrated that nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) act as chemical enhancers of human immunodeficiency virus type 1 (HIV-1) RT dimerization. In the current study, we sought to define the role of key residues (101, 103, 108, 181, 188, 190, 225 and 318) in the NNRTI-bind...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016208783885065

    authors: Figueiredo A,Zelina S,Sluis-Cremer N,Tachedjian G

    更新日期:2008-03-01 00:00:00

  • Factors influencing adherence to highly active antiretroviral therapy in Spain.

    abstract:BACKGROUND:Multiple factors have been previously described which could influence adherence to HAART. Our objective is to determine the fundamental factors which influence adherence to highly active antiretroviral therapy in our population. METHODS:A cross-sectional study was made selecting 143 outpatients attending ou...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016206776055075

    authors: Moralejo L,Inés S,Marcos M,Fuertes A,Luna G

    更新日期:2006-04-01 00:00:00

  • Bacterial colonization and beta defensins in the female genital tract in HIV infection.

    abstract::Beta defensins are antimicrobial peptides that serve to protect the host from microbial invasion at skin and mucosal surfaces. Here we explore the relationships among beta defensin levels, total bacterial colonization, and colonization by bacterial vaginosis (BV)-related bacteria and lactobacilli in the female genital...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016212802429848

    authors: Jiang W,Ghosh SK,Flyckt R,Kalinowska M,Starks D,Jurevic R,Weinberg A,Lederman MM,Rodriguez B

    更新日期:2012-09-01 00:00:00

  • The TLR4 ASP299GLY polymorphism is a risk factor for active tuberculosis in Caucasian HIV-infected patients.

    abstract:INTRODUCTION:Tuberculosis (TB) is a pandemic infectious disease especially frequent in HIV-infected patients. Toll-like receptor (TLR) 4 has been described to play a main role in the innate immunity against TB. In fact, single nucleotide polymorphisms (SNPs) in TLRs may influence AIDS disease progression. The associati...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016210791111052

    authors: Pulido I,Leal M,Genebat M,Pacheco YM,Sáez ME,Soriano-Sarabia N

    更新日期:2010-04-01 00:00:00

  • Qualitative and quantitative variables that affect the potency of Fc- mediated effector function in vitro and in vivo: considerations for passive immunization using non-neutralizing antibodies.

    abstract::Passive immunization studies in non-human primates have established unequivocally that virus neutralization can prevent infection, providing the impetus for current intense efforts to identify immunogens that elicit broadly neutralizing antibodies in humans. Although Fc-mediated effector function may also contribute t...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/1570162x113116660060

    authors: Lewis GK

    更新日期:2013-07-01 00:00:00

  • Roles of HIV-1 Env variable regions in viral neutralization and vaccine development.

    abstract::A major focus of HIV-1 vaccine development has been directed towards a limited number of broadly conserved epitopes in the Envelope (Env) proteins that are sensitive neutralization targets in many primary isolates. However, evidence suggests that these epitopes are poorly immunogenic; similar antibodies are rarely pro...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/157016207782418470

    authors: Pinter A

    更新日期:2007-11-01 00:00:00

  • Applying Triple-Matrix Masking for Privacy Preserving Data Collection and Sharing in HIV Studies.

    abstract:BACKGROUND:Many HIV research projects are plagued by the high missing rate of selfreported information during data collection. Also, due to the sensitive nature of the HIV research data, privacy protection is always a concern for data sharing in HIV studies. METHODS:This paper applies a data masking approach, called t...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162x13666151029102539

    authors: Pei Q,Chen S,Xiao Y,Wu SS

    更新日期:2016-01-01 00:00:00

  • Formulation and delivery of microbicides.

    abstract::The development of pre-exposure prophylactics or microbicide products for the reduction or elimination of the sexual transmission of HIV has numerous challenges or barriers to success. Historically traditional dosage forms such as gels have been developed in the field but more recently controlled release dosage forms ...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/157016212799304599

    authors: Agashe H,Hu M,Rohan L

    更新日期:2012-01-01 00:00:00

  • Polymorphic receptors of the innate immune system (MBL/MASP-2 and TLR2/4) and susceptibility to pneumococcal bacteremia in HIV-infected patients: a case-control study.

    abstract:UNLABELLED:Some deficient genetic polymorphisms of the innate immune system have been correlated to a higher susceptibility to different infections, especially in immunocompromised patients. The possible association between an increased incidence of pneumococcal bacteremia in HIV-infected patients, and deficient polymo...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016209787581382

    authors: Horcajada JP,Lozano F,Muñoz A,Suarez B,Fariñas-Alvarez C,Almela M,Smithson A,Martínez E,Mallolas J,Mensa J,Gatell JM

    更新日期:2009-03-01 00:00:00

  • Profile of HIV-1 infected patients from an AIDS clinic in Beijing from 2007-2008.

    abstract::While significant progress has been made since 2003 when a comprehensive treatment, prevention and control program was implemented to combat the HIV/AIDS epidemic in China, new challenges are emerging. There have been limited direct case reports on profiles of HIV/AIDS patients under care at unique clinical settings i...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016210793499169

    authors: Jiao Y,Zhang T,Wang S,Liu Q,Zhou H,Lu S,Wu H

    更新日期:2010-10-01 00:00:00

  • Temporal Trends in the Epidemiology of HIV in Turkey.

    abstract:OBJECTIVE:The aim of this study was to analyze the temporal trends of HIV epidemiology in Turkey from 2011 to 2016. METHODS:Thirty-four teams from 28 centers at 17 different cities participated in this retrospective study. Participating centers were asked to complete a structured form containing questions about epidem...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162X18666200427223823

    authors: Erdinc FS,Dokuzoguz B,Unal S,Komur S,Inkaya AC,Inan D,Karaoglan I,Deveci A,Celen MK,Kose S,Erben N,Senturk GC,Heper Y,Kutlu SS,Hatipoglu CA,Sumer S,Kandemir B,Sirmatel F,Bayindir Y,Yilmaz E,Ersoy Y,Kazak E,Yil

    更新日期:2020-01-01 00:00:00

  • Efficacy, tolerability and virological consequences of long-term use of unboosted atazanavir plus 2 NRTIs in HIV-infected patients.

    abstract:PURPOSE:Switch to unboosted atazanavir (ATV) is an attractive option due to convenience and tolerability in HIV-positive patients. With limited available data we investigated the determinants of long-term efficacy and the consequences of virological failure of unboosted atazanavir-based regimens. METHODS:Retrospective...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162x12666140807151616

    authors: Bonora S,Calcagno A,Vigano O,Bigliano P,Marinaro L,Colella E,Orofino G,Trentini L,Tettoni MC,D'Avolio A,Mercadante S,Galli M,Di Perri G,Rusconi S

    更新日期:2014-01-01 00:00:00

  • Dietary intake and physical activity in a Canadian population sample of male patients with HIV infection and metabolic abnormalities.

    abstract::Objective was to assess dietary intake and physical activity in a Canadian population sample of male patients with HIV and metabolic abnormalities and to compare the data to Canadian recommendations. Sixty-five HIV-infected men with at least one feature associated with the metabolic syndrome (insulin resistance, dysli...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/157016208783571973

    authors: Arendt BM,Aghdassi E,Mohammed SS,Fung LY,Jalali P,Salit IE,Allard JP

    更新日期:2008-01-01 00:00:00

  • The Role of IL-27 and its Receptor in the Pathogenesis of HIV/AIDS and Anti-viral Immune Response.

    abstract:BACKGROUND:Cytokines have been widely demonstrated to involve in the pathogenesis of AIDS and the mechanisms of antiretroviral therapy. Interleukin 27 (IL-27) is a new member of the IL-12 cytokine family and has been shown to interfere HIV-1 virus replication with controversial findings. This study is to investigate th...

    journal_title:Current HIV research

    pub_type: 杂志文章

    doi:10.2174/1570162X15666170517130339

    authors: Zheng YH,Xiao SL,He B,He Y,Zhou HY,Chen Z,Zheng LW,He M,Wang HY,Lin YH,Cao J

    更新日期:2017-01-01 00:00:00

  • Hodgkin lymphoma in HIV positive patients.

    abstract::Hodgkin lymphoma (HL) represents one of the most common types of a non-AIDS-defining tumour that occurs in the HIV population, and its incidence is increasing in the post Highly Active Anti-retroviral Therapy (HAART) era. Despite the aggressiveness of that disease, the outcome of patients with HIV-HL has improved with...

    journal_title:Current HIV research

    pub_type: 杂志文章,评审

    doi:10.2174/157016210790442704

    authors: Mounier N,Spina M,Spano JP

    更新日期:2010-03-01 00:00:00