Abstract:
:Although hepatitis B serology screening has been recommended for HIV care, it has not been routinely performed. We aimed to assess compliance and timing of hepatitis B serology screening among HIV-infected patients in a resource-limited setting. A cross-sectional study was conducted in Thailand. Compliance, timing of hepatitis B serology screening, and factors associated with no HBsAg screening were determined. A total of 416 HIV-infected patients with 61% males were enrolled. Median (range) age at HIV diagnosis was 34 (16-75) years and 92% had heterosexual risk. Proportion of HBsAg screening and prevalence of positive HBsAg were 69.2% and 9.0%, respectively. There was no difference in the proportion of no HBsAg screening during the period 1990-2008 (p = 0.865). Proportion of anti-HBs and anti-HBc screening were 40.9% and 21.2%, respectively. HBsAg was screened before or on the day of anti-HIV testing in 9.1% and before antiretroviral therapy (ART) initiation in 27.2%. By Kaplan-Meier analysis, median time from anti-HIV testing to HBsAg screening was 55.9 (95% confidence interval [CI] 43.9, 68.3) months. By multivariate logistic regression, duration of HIV infection (odds ratio [OR] 1.14; 95% CI 1.07, 1.21), no anti-HBs screening (OR 1.65; 95% CI 1.4-2.63), and no anti-HCV screening (OR 2.60; 95% CI 1.62, 4.17) were associated with no HBsAg screening before ART initiation. In conclusion, compliance with hepatitis B serology screening was relatively low and late. Educational program regarding hepatitis B serology screening, identification of barriers, and interventions to eliminate these barriers in resource-limited settings are crucial to improve HIV care.
journal_name
Curr HIV Resjournal_title
Current HIV researchauthors
Kiertiburanakul S,Chotiprasitsakul D,Atamasirikul K,Sungkanuparph Sdoi
10.2174/157016211794582669subject
Has Abstractpub_date
2011-01-01 00:00:00pages
54-60issue
1eissn
1570-162Xissn
1873-4251pii
ABS-121journal_volume
9pub_type
杂志文章abstract::In the HAART era Kaposi's sarcoma (KS) remains the second most frequent tumor in HIV-infected patients worldwide, and it has become the most common cancer in Sub-Saharan Africa. In western countries the risk for KS in men having sex with men (MSM) is 5 to 10 times higher compared to other groups of individuals practic...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/157016209789973619
更新日期:2009-11-01 00:00:00
abstract::Opioid use in HIV infection has been associated with an increased frequency of neurological disease and cognitive impairment and vitamin A deficiency has been linked to progressive HIV disease in drug users. In this report the potential effects of these factors, alone and in combination, on gamma amino butyric acid (G...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016212802138715
更新日期:2012-07-01 00:00:00
abstract::Over the past 10 years substantial progress has been made in the implementation of prevention of mother-to-child transmission of HIV (PMTCT) interventions in Sub-Saharan Africa (SSA). In spite of this, new pediatric infections remain unacceptably high, contributing the majority (>90%) of the estimated 390,000 infectio...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/1570162x11311020007
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:HIV lipodystrophy is characterised by abnormal adipose tissue distribution and metabolism, as a result of altered adipocyte function and gene expression. The protease inhibitor ritonavir is associated with the development of lipodystrophy. Quantifying changes in adipogenic gene expression in the presence of r...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162x13666150806110238
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Transmitted drug resistance (TDR) remains a significant threat to Human immunodeficiency virus (HIV) infected patients that are not exposed to antiretroviral treatment. Although, combined antiretroviral therapy (cART) has reduced deaths among infected individuals, emergence of drug resistance is gradually on...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162X17666191004093433
更新日期:2019-01-01 00:00:00
abstract::The present study assessed the phenotypic aspects of oral-cavity Candida albicans isolates from 300 HIV-1- positive patients, relating the most commonly investigated virulence factors (enzyme typing and germ-tube formation) to the most common morphotypes. The samples were seeded into specific media for isolation and s...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162x113119990042
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:HIV infection induces alterations in the gut-associated lymphoid tissue (GALT) that constitutes the most important site for viral replication due to the extensive presence of effector memory T-cells. In the case of HIV-controllers, several studies have reported fewer peripheral alterations and conserved immu...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162X17666190130115113
更新日期:2018-01-01 00:00:00
abstract::Immunization is an important measure to protect HIV-infected children and adults against certain vaccine preventable diseases. However, the antibody response, which is associated with the level of CD4+ T cell count, is frequently impaired in this group of patients. Certain vaccines enhance virus replication and transi...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/1570162043351084
更新日期:2004-10-01 00:00:00
abstract::AIDS is a globalized infectious disease. In 2014, UNAIDS launched a global project of "90-90-90" to end the HIV epidemic by 2030. The second and third 90 require 90% of HIV-1 infected individuals receiving antiretroviral therapy (ART) and durable virological suppression. However, wide use of ART will greatly increase ...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162X17666190927154110
更新日期:2019-01-01 00:00:00
abstract::An estimated 800,000 children acquired HIV-infection in 2002, most as a result of mother-to-child transmission (MTCT), and vertically-acquired HIV infection continues to be of major public health importance. Prevention of MTCT is possible with a combination of interventions including antiretroviral therapy (ART) (usua...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/1570162033485140
更新日期:2003-10-01 00:00:00
abstract::To promote the initiation of reverse transcription, the HIV-1 virus uses a host tRNA as a primer, tRNA(3Lys). The annealing of tRNA(3Lys) to the viral RNA requires the breaking of the 3D structure of the tRNA and RNA rearrangements, to form a stable initiation complex recognised by the reverse transcriptase. The annea...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/1570162053506919
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Although HIV and injury contribute substantially to disease burdens in lowand middle-income countries (LMIC), their intersection is poorly characterized. OBJECTIVE:This systematic review assessed the prevalence and associated mortality impact of HIVseropositivity among injured patients in LMIC. METHODS:A s...
journal_title:Current HIV research
pub_type: 杂志文章,meta分析,评审
doi:10.2174/1570162X15666170920112743
更新日期:2017-11-23 00:00:00
abstract:OBJECTIVE:Identifying the genetic variability in vertically transmitted viruses in early infancy is important to understand the disease progression. Being important in HIV-1 disease pathogenesis, vpu gene, isolated from young infants was investigated to understand the viral characteristics. METHOD:Blood samples were o...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162X16666180219154601
更新日期:2018-01-01 00:00:00
abstract::Antiretroviral (ARV) prophylaxis for prevention of mother to child transmission (MTCT) of HIV could affect hemoglobin (Hb) development of infants. A cross-sectional descriptive study was conducted in 24 HIV-infected and 21 HIV-uninfected pregnancies. ARV drugs were administered to HIV-infected pregnancies at 21 weeks ...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162x12666140713170800
更新日期:2014-01-01 00:00:00
abstract::Two HIV-1 non B isolates, 98US_MSC5007 and 98US_MSC5016, which have been identified amongst the US Army personnel serving abroad, are known to have originated from other nations. Notwithstanding, they are categorized as American strains. This is because their countries of origin are unknown. American isolates are basi...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162x113119990046
更新日期:2013-06-01 00:00:00
abstract::Previous studies have demonstrated that nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) act as chemical enhancers of human immunodeficiency virus type 1 (HIV-1) RT dimerization. In the current study, we sought to define the role of key residues (101, 103, 108, 181, 188, 190, 225 and 318) in the NNRTI-bind...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016208783885065
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Multiple factors have been previously described which could influence adherence to HAART. Our objective is to determine the fundamental factors which influence adherence to highly active antiretroviral therapy in our population. METHODS:A cross-sectional study was made selecting 143 outpatients attending ou...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016206776055075
更新日期:2006-04-01 00:00:00
abstract::Beta defensins are antimicrobial peptides that serve to protect the host from microbial invasion at skin and mucosal surfaces. Here we explore the relationships among beta defensin levels, total bacterial colonization, and colonization by bacterial vaginosis (BV)-related bacteria and lactobacilli in the female genital...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016212802429848
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION:Tuberculosis (TB) is a pandemic infectious disease especially frequent in HIV-infected patients. Toll-like receptor (TLR) 4 has been described to play a main role in the innate immunity against TB. In fact, single nucleotide polymorphisms (SNPs) in TLRs may influence AIDS disease progression. The associati...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016210791111052
更新日期:2010-04-01 00:00:00
abstract::Passive immunization studies in non-human primates have established unequivocally that virus neutralization can prevent infection, providing the impetus for current intense efforts to identify immunogens that elicit broadly neutralizing antibodies in humans. Although Fc-mediated effector function may also contribute t...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/1570162x113116660060
更新日期:2013-07-01 00:00:00
abstract::A major focus of HIV-1 vaccine development has been directed towards a limited number of broadly conserved epitopes in the Envelope (Env) proteins that are sensitive neutralization targets in many primary isolates. However, evidence suggests that these epitopes are poorly immunogenic; similar antibodies are rarely pro...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/157016207782418470
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Many HIV research projects are plagued by the high missing rate of selfreported information during data collection. Also, due to the sensitive nature of the HIV research data, privacy protection is always a concern for data sharing in HIV studies. METHODS:This paper applies a data masking approach, called t...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162x13666151029102539
更新日期:2016-01-01 00:00:00
abstract::The development of pre-exposure prophylactics or microbicide products for the reduction or elimination of the sexual transmission of HIV has numerous challenges or barriers to success. Historically traditional dosage forms such as gels have been developed in the field but more recently controlled release dosage forms ...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/157016212799304599
更新日期:2012-01-01 00:00:00
abstract:UNLABELLED:Some deficient genetic polymorphisms of the innate immune system have been correlated to a higher susceptibility to different infections, especially in immunocompromised patients. The possible association between an increased incidence of pneumococcal bacteremia in HIV-infected patients, and deficient polymo...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016209787581382
更新日期:2009-03-01 00:00:00
abstract::While significant progress has been made since 2003 when a comprehensive treatment, prevention and control program was implemented to combat the HIV/AIDS epidemic in China, new challenges are emerging. There have been limited direct case reports on profiles of HIV/AIDS patients under care at unique clinical settings i...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016210793499169
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the temporal trends of HIV epidemiology in Turkey from 2011 to 2016. METHODS:Thirty-four teams from 28 centers at 17 different cities participated in this retrospective study. Participating centers were asked to complete a structured form containing questions about epidem...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162X18666200427223823
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:Switch to unboosted atazanavir (ATV) is an attractive option due to convenience and tolerability in HIV-positive patients. With limited available data we investigated the determinants of long-term efficacy and the consequences of virological failure of unboosted atazanavir-based regimens. METHODS:Retrospective...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162x12666140807151616
更新日期:2014-01-01 00:00:00
abstract::Objective was to assess dietary intake and physical activity in a Canadian population sample of male patients with HIV and metabolic abnormalities and to compare the data to Canadian recommendations. Sixty-five HIV-infected men with at least one feature associated with the metabolic syndrome (insulin resistance, dysli...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/157016208783571973
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Cytokines have been widely demonstrated to involve in the pathogenesis of AIDS and the mechanisms of antiretroviral therapy. Interleukin 27 (IL-27) is a new member of the IL-12 cytokine family and has been shown to interfere HIV-1 virus replication with controversial findings. This study is to investigate th...
journal_title:Current HIV research
pub_type: 杂志文章
doi:10.2174/1570162X15666170517130339
更新日期:2017-01-01 00:00:00
abstract::Hodgkin lymphoma (HL) represents one of the most common types of a non-AIDS-defining tumour that occurs in the HIV population, and its incidence is increasing in the post Highly Active Anti-retroviral Therapy (HAART) era. Despite the aggressiveness of that disease, the outcome of patients with HIV-HL has improved with...
journal_title:Current HIV research
pub_type: 杂志文章,评审
doi:10.2174/157016210790442704
更新日期:2010-03-01 00:00:00