Studies on function of Hb Jianghua [beta 120 (GH3) Lys----Ile].

Abstract:

:Hemoglobin Jianghua (Hb Jianghua) is a new fast--moving hemoglobin variant found in China, being named after the county where it was detected. Having its primary structure analysed, we report in this paper the results of studies on its function. The absorption spectrum, response to allosteric effectors and oxygen equilibrium of the chromatographically purified Hb Jianghua showed its characteristics similar to those of purified Hb A. Its alkaline Bohr effect was normal. This indicates that a substitution of isoleucine for the 120th lysine residue of the beta chain had no significant influence upon the function of Hb molecule.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Lu YQ,Huang CH,Hu HL,Huang PY

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

3-6

issue

1

eissn

0366-6999

issn

2542-5641

journal_volume

103

pub_type

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