Laparoendoscopic single-site radical prostatectomy: technique and initial outcomes.

Abstract:

BACKGROUND:Laparoendoscopic single-site surgery radical prostatectomy (LESS-RP) is a challenging urological procedure and needs to be further evaluated. This study was undertaken to illustrate the safety and initial results of pure LESS-RP with conventional available instruments. METHODS:A prospective clinical database was established in September 2010 to assess the outcome following the introduction of LESS-RP at our institution. By June 2012, six procedures had been performed. The mean patient age was 74.7 (74.0 - 76.0) years. The mean body mass index (BMI) was 23.8 (19.5 - 32.2) kg/m(2). The LESS-RP was preformed through an extra-peritoneal approach using single port access with QudaPort, 0° lens 5 mm flexible tip video-laparoscope and available conventional laparoscopic instruments. Parameters assessed were operative time, estimated blood loss, intra-operative complications, drainage time, postoperative pain score (visual analogue pain scale (VAPS), 0 - 10), pathological results, and postoperative prostate specific antigen (PSA) levels. RESULTS:LESS-RP was completed for all six cases without additional trocar placement or conversion to standard laparoscopic or open radical prostatectomy. The mean operative times were 252.5 (190.0 - 305.0) minutes, estimated blood loss was 300 (100 - 500 ml). There was no documentable intraoperative complication. The mean wound-drainage time was 5.2 (2.0 - 7.0) days, and the first postoperative day VAPS was 0.8 (0 - 3.0). Final pathological staging was pT2aN0M0 in four cases and pT2cN0M0 in two cases. Surgical margins were negative for all cases. The one-month post-operative PSA was less than 0.02 ng/ml in each case. All patients were continent without pad usage at 1 year postoperatively. CONCLUSION:The technique of pure LESS-RP is feasible and early outcomes are acceptable.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Zhu G,Zhang YQ,Grange P,Walsh K,Jin B,Zhang YG,Chen X,Wang X,Wei D,Wan B,Wang JY

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

3815-20

issue

21

eissn

0366-6999

issn

2542-5641

journal_volume

125

pub_type

杂志文章
  • A clinical neurophysiology study of Hirayama disease.

    abstract:BACKGROUND:Hirayama disease is a rare disease characterized by juvenile-onset of asymmetric amyotrophy, of which etiology has not been clarified. The aim of our study was to investigate the clinical and neurophysiologic characteristics of Hirayama disease. METHODS:Neurophysiological tests, including nerve conduction s...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang XN,Cui LY,Liu MS,Guan YZ,Li BH,DU H

    更新日期:2012-03-01 00:00:00

  • Angiographic prevalence of myocardial bridging in a defined very large number of Chinese patients with chest pain.

    abstract:BACKGROUND:Muscle fibers overlying the intramyocardial segment of an epicardial coronary artery are termed myocardial bridging (MB). Variable prevalence of MB has been described at autopsy and angiographic series with small and large sample size studies. In addition, no similar study was reported in Chinese population....

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li JJ,Shang ZL,Yao M,Li J,Yang YJ,Chen JL,Qiao SB,Ma WH,Qin XW,Liu HB,Wu YJ,Yuan JQ,Chen J,You SJ,Dai J,Xu B,Xia R,Gao RL

    更新日期:2008-03-05 00:00:00

  • T8590C polymorphism of CYP4A11 is a risk factor for hypertension: a meta-analysis.

    abstract:BACKGROUND:T8590C polymorphism of CYP4A11 has been associated with hypertension, though with conflicting results. The aim of this study was to quantitatively summarize the evidence for CYP4A11 T8590C polymorphism and hypertension risk. METHODS:Electronic search of PubMed and the Chinese Biomedicine database was conduc...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,meta分析

    doi:

    authors: Jiang Y,Hou J,Zhang Q,Tang W,Luo Y

    更新日期:2014-01-01 00:00:00

  • The clinical and epidemiological significance of serum PreS1/anti-PreS1 in HBV infection.

    abstract:OBJECTIVE:To investigate whether PreS1 antigen and/or anti-PreS1 antibody in serum might have some significance different from routine hepatitis B virus (HBV) markers in hepatitis B virus infection. METHODS:Forty-six acute hepatitis B patients and 377 chronic persistent hepatitis patients were examined to assess the c...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Mi Z,Feng F,Zhang X,Lian Z,Wang H,Tong Y

    更新日期:1999-04-01 00:00:00

  • Characteristics of coronary microvascular lesions in autopsied elderly with hypertensive left ventricular hypertrophy.

    abstract:OBJECTIVE:To observe the characteristics of coronary microvascular lesions (CML) in the autopsied elderly cases with hypertensive left ventricular hypertrophy (LVH) and the difference of CML among the groups of essential hypertension (EHT), coronary heart disease (CHD) and diabetes (NIDDM) also with LVH. METHODS:A ret...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li X,Li R,Yu W,Shi H,Wei L

    更新日期:2002-05-01 00:00:00

  • Recurrent Septic Pulmonary Embolism Related to an Implanted Central Venous Access Port Device.

    abstract:: ...

    journal_title:Chinese medical journal

    pub_type: 信件

    doi:10.4103/0366-6999.247196

    authors: Hong G,Kim YS

    更新日期:2018-12-20 00:00:00

  • Endoplasmic Reticulum Stress Induces the Early Appearance of Pro-apoptotic and Anti-apoptotic Proteins in Neurons of Five Familial Alzheimer's Disease Mice.

    abstract:BACKGROUND:Amyloid β (Aβ) deposits and the endoplasmic reticulum stress (ERS) are both well established in the development and progression of Alzheimer's disease (AD). However, the mechanism and role of Aβ-induced ERS in AD-associated pathological progression remain to be elucidated. METHODS:The five familial AD (5×FA...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.194643

    authors: Shen H,Pan XD,Zhang J,Zeng YQ,Zhou M,Yang LM,Ye B,Dai XM,Zhu YG,Chen XC

    更新日期:2016-12-05 00:00:00

  • Bone marrow-derived mesenchymal stem cells protect rats from endotoxin-induced acute lung injury.

    abstract:BACKGROUND:Acute lung injury (ALI) is a serious and common condition for which there are currently no specific strategies for treatment. Recent studies have suggested that bone marrow-derived multipotent mesenchymal stem cells (MSCs) may have therapeutic applications in multiple clinical disorders. We explored the biol...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liang ZX,Sun JP,Wang P,Tian Q,Yang Z,Chen LA

    更新日期:2011-09-01 00:00:00

  • A bicistronic retroviral vector to introduce drug resistance genes into human umbilical cord blood CD34+ cells to improve combination chemotherapy tolerance.

    abstract:OBJECTIVE:To study whether human umbilical cord blood CD34+ cells transduced with human aldehyde dehydrogenase class-1 (ALDH-1) and multidrug resistance gene (MDR1) have increases resistance to 4-Hydroperoxycyclo-phosphamide (4-HC) and P-glycoprotein effluxed drugs. METHODS:A bicistronic retroviral vector G1Na-ALDH1-I...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang J,Chen Z,Xia X,Lu D,Xue J,Ruan C

    更新日期:2001-01-01 00:00:00

  • dl-3-n-butylphthalide reduces brain damage in mice with closed head injury.

    abstract:OBJECTIVE:To investigate the protective effect of dl-3-n-butylphthalide (NBP) as an anti-cerebral ischemic drug on brain damage 24 h after closed head injury in mice. METHODS:Closed head injury was induced by dropping a 50-g weight from a height of 18 cm on a metal impounder resting on the parietal bone in mice. RESU...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chong Z,Feng Y

    更新日期:2000-07-01 00:00:00

  • Orthotopic ileal neobladder similar to original bladder.

    abstract:OBJECTIVE:To report the surgical techniques and results of an 8-year follow-up study of 42 patients with a modified orthotopic ileal neobladder restoring normal anatomical relationship. METHODS:Total cystoprostatectomy was performed extraperitoneally. A 45 - 50 cm segment of the ileal loop was isolated, detubularized,...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Huang J,Xu K,Yao Y,Guo Z,Lin T,Jiang C

    更新日期:2003-12-01 00:00:00

  • Recombinant Human Erythropoietin Augments Neovascularization Responses in a Neonatal Rat Model of Premature Brain Damage by Phosphatidylinositol 3 Kinase/Akt Pathway.

    abstract:BACKGROUND:Recombinant human-erythropoietin (rh-EPO) has therapeutic efficacy for premature infants with brain damage during the active rehabilitation and anti-inflammation. In the present study, we found that the rh-EPO was related to the promotion of neovascularization. Our aim was to investigate whether rh-EPO augme...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.202744

    authors: Yu DF,Zhu LH,Jiang L

    更新日期:2017-04-05 00:00:00

  • Effect of medial meniscus extrusion on arthroscopic surgery outcome in the osteoarthritic knee associated with medial meniscus tear: a minimum 4-year follow-up.

    abstract:BACKGROUND:The potential benefit of arthroscopic surgery for osteoarthritic knee associated with medial meniscus tear is controversial. This study was conducted to determine the effect of pre-operative medial meniscus extrusion (MME) on arthroscopic surgery outcomes in the osteoarthritic knee associated with medial men...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000492

    authors: Wang YX,Li ZL,Li J,Zhao ZD,Wang HR,Hou C,Li W,Liu CH

    更新日期:2019-11-05 00:00:00

  • Structure-function interrelation and clinical effect of atrial natriuretic peptide (ANP).

    abstract::Atriopeptin III (AP III) and its six analogues were synthesized by solid phase method and their diuretic and hypotensive activities were determined. Among these analogues, analogue [D-Ala-5, D-Arg-23] AP III was nearly 10 times as potent as AP III in diuretic activity while its hypotensive activity increased only 50% ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang J,Shi P

    更新日期:1995-04-01 00:00:00

  • Postoperative stimulated thyroglobulin level and recurrence risk stratification in differentiated thyroid cancer.

    abstract:BACKGROUND:Postoperative preablative stimulated thyroglobulin (ps-Tg) has been evaluated in predicting prognosis and success of ablation regarding differentiated thyroid cancer (DTC); however, its relationship with recurrence risk and radioiodine decision-making remains uncertain, especially in Chinese DTC patients. We...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.155086

    authors: Yang X,Liang J,Li TJ,Yang K,Liang DQ,Yu Z,Lin YS

    更新日期:2015-04-20 00:00:00

  • Inflammation unmasks gabapentin's effect on A delta-fiber evoked excitatory postsynaptic currents in substantia gelatinosa neurons of rat spinal cord.

    abstract:OBJECTIVE:To study the analgesic mechanism of gabapentin, an anticonvulsant, during antinociceptive clinical treatment. METHODS:Whole-cell voltage-clamp recordings were taken from adult rat spinal cord slices to investigate the effect of gabapentin on primary afferent A delta-fiber evoked excitatory postsynaptic curre...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu Z,Xu R,Yang K

    更新日期:2003-06-01 00:00:00

  • Comparative study of optic disc measurement by Copernicus optical coherence tomography and Heidelberg retinal tomography.

    abstract:BACKGROUND:Copernicus optical coherence tomography (SOCT) is a new, ultra high-speed and high-resolution instrument available for clinical evaluation of optic nerve. The purpose of the study was to compare the agreements between SOCT and Heidelberg retinal tomography (HRT). METHODS:A total of 44 healthy normal volunte...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yang QS,Yu YJ,Li SN,Liu J,Hao YJ

    更新日期:2012-08-01 00:00:00

  • Transitional cell carcinoma associated with aristolochic acid nephropathy: most common cancer in chronic hemodialysis patients in China.

    abstract:BACKGROUND:The research of cancer in patients on hemodialysis (HD) in China has not been reported. The aim of this study was to investigate the clinical and histological features and outcomes of cancer in Chinese HD patients. METHODS:The study subjects were 49 cancer patients (1.4%) out of 3448 end stage renal disease...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou L,Cao YL,Li WG,Fu FT,Zhang L,Wang X,Shi XH

    更新日期:2012-12-01 00:00:00

  • Menopausal Symptoms and Sleep Quality During Menopausal Transition and Postmenopause.

    abstract:BACKGROUND:Menopausal symptoms and sleep difficulty were physiological processes that were affected by genetic and other factors. This study was to investigate the prevalence of menopausal symptoms and sleep quality in menopausal transition (MT) and postmenopause (PM) women in Taiyuan, Shanxi. METHODS:A community-base...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.178961

    authors: Zhang JP,Wang YQ,Yan MQ,Li ZA,Du XP,Wu XQ

    更新日期:2016-04-05 00:00:00

  • Apparent protective effect of high density lipoprotein against coronary heart disease in the elderly.

    abstract:BACKGROUND:This study was designed to evaluate the relationship between high-density lipoprotein cholesterol (HDL-C) level and acute myocardial infarction (AMI) and coronary heart disease (CHD) death and to explore the protective effect of HDL against CHD in the elderly Chinese. METHODS:Started from 1986, 1211 retiree...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li JZ,Chen ML,Wang S,Dong J,Zeng P,Hou LW

    更新日期:2004-04-01 00:00:00

  • Assessment of cardiac function and synchronicity in subjects with isolated bundle branch block using Doppler imaging.

    abstract:BACKGROUND:Using tissue Doppler imaging and conventional echocardiographic technique, we examined the cardiac function and synchronicity in individuals with isolated right bundle branch block (RBBB) or left bundle branch block (LBBB) and assessed the relationship between QRS duration and synchronicity. METHODS:Subject...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Niu HX,Hua W,Zhang S,Sun X,Wang FZ,Chen KP,Wang H,Chen X

    更新日期:2006-05-20 00:00:00

  • Characteristic dysbiosis of gut microbiota of Chinese patients with diarrhea-predominant irritable bowel syndrome by an insight into the pan-microbiome.

    abstract:BACKGROUND:Irritable bowel syndrome (IBS) is reported associated with the alteration of gut microbial composition termed as dysbiosis. However, the pathogenic mechanism of IBS remains unclear, while the studies of Chinese individuals are scarce. This study aimed to understand the concept of dysbiosis among patients wit...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000192

    authors: Wang Z,Xu CM,Liu YX,Wang XQ,Zhang L,Li M,Zhu SW,Xie ZJ,Wang PH,Duan LP,Zhu HQ

    更新日期:2019-04-20 00:00:00

  • A meta-analysis of carotid endarterectomy versus stenting in the treatment of symptomatic carotid stenosis.

    abstract:BACKGROUND:Carotid stenosis is one of the common reasons for patients with ischemic stroke, and the two invasive options carotid endarterectomy (CEA) and carotid artery stenting (CAS) are the most popular treatments. But the relative efficacy and safety of the methods are not clear. METHODS:About 521 articles related ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,meta分析

    doi:

    authors: Wang L,Liu XZ,Liu ZL,Lan FM,Shi WC,Liu J,Zhang JN

    更新日期:2013-02-01 00:00:00

  • Reevaluation of effect of albendazole on echinococcus multilocularis infection in mice and gerbils.

    abstract:OBJECTIVE:To study the effect for albendazole therapy for alveolar echinococcus infection in gerbils and mice. METHODS:Mice and gerbils were infected of metacestode tissues by intraperitoneal (i.p.) transplantation and treated with albendazole-medicated feeds. The effects were evaluated by comparison of the treated an...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu Y,Wang X,Gao J,Yao Y,Yu D

    更新日期:1998-10-01 00:00:00

  • Dermoscopy in China: current status and future prospective.

    abstract:OBJECTIVE:Dermoscopy is a useful technique for improving the diagnostic accuracy of various types of skin disorders. In China, dermoscopy has been widely accepted, and domestic researchers have made tremendous progress in the field of dermoscopy. The main purpose of this review is to summarize the current status of der...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/CM9.0000000000000396

    authors: Shen X,Yu RX,Shen CB,Li CX,Jing Y,Zheng YJ,Wang ZY,Xue K,Xu F,Yu JB,Meng RS,Cui Y

    更新日期:2019-09-05 00:00:00

  • Down-regulation of peroxisome proliferator-activated receptor γ coactivator-1α expression in fatty acid-induced pancreatic beta-cell apoptosis involves nuclear factor-κB pathway.

    abstract:BACKGROUND:Pancreatic beta-cell apoptosis induced by lipotoxicity, to a large extent, contributes to the progression of type 2 diabetes. To investigate the mechanism of free fatty acid induced apoptosis, we aimed to study the effects of palmitic acid (PA) on the apoptosis and peroxisome proliferator-activated receptor ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: He TT,Cao XP,Chen RZ,Zhu XN,Wang XL,Li YB,Xiao HP

    更新日期:2011-11-01 00:00:00

  • Anti-tumor effects of polybutylcyanoacrylate nanoparticles of diallyl trisulfide on orthotopic transplantation tumor model of hepatocellular carcinoma in BALB/c nude mice.

    abstract:BACKGROUND:Hepatocellular carcinoma (HCC) ranked the second among the causes of cancer mortality in China since the 1990s. Up to now, medication still plays an important role in the treatment of HCC. The therapies based on the allicin as a potential chemopreventive analog although is in its infancy at the present time,...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang ZM,Yang XY,Deng SH,Xu W,Gao HQ

    更新日期:2007-08-05 00:00:00

  • Noninvasive three-dimensional computed tomographic angiography in preoperative detection of intracranial arteriovenous malformations.

    abstract:OBJECTIVE:To assess the value of noninvasive three-dimensional computed tomographic angiography (3D-CTA) in preoperative detection of intracranial arteriovenous malformations (AVMs). METHODS:A prospective evaluation at a single institute over a 2-year period included 23 patients suspected of intracranial AVMs. All pat...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wu J,Chen X,Shi Y,Chen S

    更新日期:2000-10-01 00:00:00

  • Prevalence of purified protein derivative positivity in human immunodeficiency virus infected individuals in Hong Kong.

    abstract:OBJECTIVE:To study the prevalence of skin positivity to purified protein derivative (PPD) in human immunodeficiency virus (HIV)-infected patients in Hong Kong. METHODS:Consecutive clients of an HIV clinic were administered the PPD test and 2 units of PPD-RT23 were used. The area of induration was then measured in 48 t...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chan KC,Tang HW,Wong K

    更新日期:2002-07-01 00:00:00

  • Infliximab monotherapy for Chinese patients with moderate to severe plaque psoriasis: a randomized, double-blind, placebo-controlled multicenter trial.

    abstract:BACKGROUND:Tumor necrosis factor-α is a key mediator in the pathogenesis of psoriasis. Infliximab is a monoclonal antibody that specifically binds to tumor necrosis factor-α. The purpose of this study was to validate the efficacy and safety of 5 mg/kg infliximab therapy in Chinese patients with moderate to severe plaqu...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:

    authors: Yang HZ,Wang K,Jin HZ,Gao TW,Xiao SX,Xu JH,Wang BX,Zhang FR,Li CY,Liu XM,Tu CX,Ji SZ,Shen Y,Zhu XJ

    更新日期:2012-06-01 00:00:00