COPD in the elderly patient.

abstract：:Treatment strategies for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are evolving. Cyclophosphamide (CYC) plus corticosteroids (CSs) is the mainstay of therapy for generalized, multisystemic AAV. Historically, the combination of CYC plus CS was used for a minimum of 12 months, but concern a...

journal_title：Seminars in respiratory and critical care medicine

authors： Wang T,Weigt SS,Belperio JA,Lynch JP 3rd

更新日期：2011-06-01 00:00:00

abstract：:Mechanical ventilation practices in patients with acute respiratory distress syndrome (ARDS) have progressed with a growing understanding of the disease pathophysiology. Paramount to the care of affected patients is the delivery of lung-protective mechanical ventilation which prioritizes tidal volume and plateau press...

journal_title：Seminars in respiratory and critical care medicine

authors： Sklar MC,Patel BK,Beitler JR,Piraino T,Goligher EC

更新日期：2019-02-01 00:00:00

abstract：:Cystic fibrosis (CF) is now more common in adults than children in countries with well-developed health care systems. The number of adults continues to increase and will further increase if the new cystic fibrosis transmembrane conductance regulator (CFTR) modulators are disease modifying. Most of the complex morbidit...

journal_title：Seminars in respiratory and critical care medicine

authors： Elborn JS

更新日期：2019-12-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a systemic disease, characterized by symmetric joint involvement, but it can also affect other organ systems, including the lungs. The better-known pulmonary manifestations of RA are interstitial lung disease, rheumatoid nodules, and pleural effusions. Less common manifestations include br...

journal_title：Seminars in respiratory and critical care medicine

authors： Gauhar UA,Gaffo AL,Alarcón GS

更新日期：2007-08-01 00:00:00

abstract：:Pseudomonas aeruginosa is a formidable pathogen in the infection arena. It is able to easily adapt to the environment which it inhabits and can also colonize and invade the human host to cause serious infections. In 2011, it was responsible for 7.1% of all health care-associated infection in the United States. The mor...

journal_title：Seminars in respiratory and critical care medicine

authors： McCarthy K

更新日期：2015-02-01 00:00:00

abstract：:Malignant pleural mesothelioma is a rare cancer associated with asbestos exposure and portends a dismal prognosis. Its worldwide incidence has been increasing, and treatment options are currently suboptimal and noncurative. However, since the turn of the century, several encouraging steps have been made toward improvi...

journal_title：Seminars in respiratory and critical care medicine

authors： Kim RY,Sterman DH,Haas AR

更新日期：2019-06-01 00:00:00

abstract：:Pneumothorax is a common clinical entity that may present to a wide variety of medical specialties. Primary pneumothorax (in the presence of no known underlying lung disease) and secondary pneumothorax (in known lung disease) are distinct entities with varied etiology, treatment, and prognosis. Diagnosis is usually ba...

journal_title：Seminars in respiratory and critical care medicine

authors： Rahman NM,Davies RJ,Gleeson FV

更新日期：2008-08-01 00:00:00

abstract：:Asthma is a heterogeneous disorder with a complex etiology. Prevalence rates for asthma have been increasing in many countries over the past few decades. While it is unclear why this increase is occurring, the variation reported in asthma prevalence and severity associated with ethnicity offers some insight into the d...

journal_title：Seminars in respiratory and critical care medicine

authors： Moraes TJ,Sears MR,Subbarao P

更新日期：2018-02-01 00:00:00

abstract：:Ultrasonography of the thorax has become a more recognized tool in pulmonary medicine, thanks to continuing clinical research that has proven its many valuable roles in the day-to-day management of pulmonary and pleural diseases. Ultrasound examination is a cost-effective imaging modality that permits the pulmonologis...

journal_title：Seminars in respiratory and critical care medicine

authors： Shojaee S,Argento AC

更新日期：2014-12-01 00:00:00

abstract：:Practicing pulmonologists are often faced with the question of whether a lung disease is related to something in the patient's workplace, home, or recreational environment. Recognizing a lung disease as exposure related creates both opportunities and obligations for clinicians. In addition to managing the patient, the...

journal_title：Seminars in respiratory and critical care medicine

authors： Rose CS,Lynch DA,Cool CD

更新日期：2008-12-01 00:00:00

abstract：:Among immunocompromised individuals, members of the human Herpesviridae family are frequently encountered pathogens. Cytomegalovirus, herpes simplex virus 1 and 2, varicella zoster virus, Epstein-Barr virus, and human herpesvirus-6, -7, and -8 all establish latency after infection and can reactivate during periods of ...

journal_title：Seminars in respiratory and critical care medicine

authors： Reid GE,Lynch JP 3rd,Weigt S,Sayah D,Belperio JA,Grim SA,Clark NM

更新日期：2016-08-01 00:00:00

abstract：:Critically ill intensive care unit (ICU) patients often require sedation to tolerate life-saving interventions such as mechanical ventilation. Pain, anxiety, and delirium all contribute to patient distress and agitation which can interfere with ICU medical care if not addressed and treated appropriately. Sedation prac...

journal_title：Seminars in respiratory and critical care medicine

authors： DeBiasi EM,Akgün KM,Pisani M

更新日期：2015-12-01 00:00:00

abstract：:With the improving survival of cystic fibrosis (CF) patients and the advent of highly effective cystic fibrosis transmembrane conductance regulator therapy, the clinical spectrum of this complex multisystem disease continues to evolve. One of the most important clinical events for patients with CF in the course of thi...

journal_title：Seminars in respiratory and critical care medicine

authors： Goss CH

更新日期：2019-12-01 00:00:00

abstract：:Despite advances in positive pressure therapy for obstructive sleep apnea, compliance continues to be a problem for many patients. Sleep apnea surgery is a viable option for patients who are intolerant of positive pressure therapy. This review presents the current state of the art in sleep apnea surgery, including air...

journal_title：Seminars in respiratory and critical care medicine

authors： Li KK

更新日期：2005-02-01 00:00:00

abstract：:Mortality from the adult respiratory distress syndrome (ARDS) and the infant respiratory distress syndrome remains high despite numerous interventions and modalities. Perfluorocarbons (PFC) are inert liquids that can dissolve large amounts of oxygen and carbon dioxide and can be used as respiratory media. Partial liqu...

journal_title：Seminars in respiratory and critical care medicine

authors： Hadjiliadis D

更新日期：2000-01-01 00:00:00

abstract：:Despite significant progress in the field of transplant immunology, acute cellular rejection (ACR) remains a very frequent complication after lung transplantation (LTx), with almost 30% of LTx recipients experiencing at least one episode of treated ACR during the first year of follow-up. Most episodes respond to the f...

journal_title：Seminars in respiratory and critical care medicine

authors： Koutsokera A,Levy L,Pal P,Orchanian-Cheff A,Martinu T

更新日期：2018-04-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer death in the world. However, there is large geographic variation internationally and within nations. Despite the fact that many causes of lung cancer have been established, cigarette smoking is the principal cause. Accounting for historical prevalence of cigarette smoking is ...

journal_title：Seminars in respiratory and critical care medicine

authors： Alberg AJ,Nonemaker J

更新日期：2008-06-01 00:00:00

abstract：:Pulmonary fibrosis is a devastating disease that occurs in association with environmental exposures, several inherited diseases, collagen vascular disease, as well as in an idiopathic form. Epithelial cell damage, excessive fibroblast proliferation, upregulation of extracellular matrix production, and attenuated matri...

journal_title：Seminars in respiratory and critical care medicine

authors： Wurfel MM,Raghu G

更新日期：2002-04-01 00:00:00

abstract：:The evolution of scientific investigation in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is replete with examples of effective bench-to-bedside transitions, pioneering research methodology, and international collaboration. This article highlights for clinicians a selection of challenges and ...

journal_title：Seminars in respiratory and critical care medicine

authors： Meade MO,Lamontagne F

更新日期：2013-08-01 00:00:00

abstract：:Although the lung is frequently involved by disseminated lymphoma, isolated pulmonary lymphoma is rare, accounting for less than 1% of all extranodal localized disease. Three broad categories of lymphoma of the lung require recognition: in rare instances, large B cell type lymphoma can present primarily in the lung; a...

journal_title：Seminars in respiratory and critical care medicine

authors： Chilosi M,Zinzani PL,Poletti V

更新日期：2005-10-01 00:00:00

abstract：:The diaphragm is the most important muscle of ventilation. Its contraction is key to the development of intrathoracic pressures. Diseases that affect diaphragmatic function result in decreased pressure-generating capacity by the respiratory muscles. If the involvement is severe or if there is underlying respiratory pa...

journal_title：Seminars in respiratory and critical care medicine

authors： Celli BR

更新日期：2002-06-01 00:00:00

abstract：:Hepatic sarcoidosis is a relatively common manifestation of extrapulmonary sarcoidosis. It occurs in 20 to 30% of cases and is rarely severe. However, a cluster of patients may develop severe complications such as cirrhosis and portal hypertension. In this review, we describe the current knowledge of clinical, biologi...

journal_title：Seminars in respiratory and critical care medicine

authors： Rossi G,Ziol M,Roulot D,Valeyre D,Mahévas M

更新日期：2020-10-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is primarily a disease of the elderly. Although NSCLC is the leading cause of cancer death in the United States and the overall prognosis of this disease is poor, treatment improves survival compared with best supportive care, independent of the stage of disease. Elderly patients hav...

journal_title：Seminars in respiratory and critical care medicine

authors： Sequist LV,Fidias P

更新日期：2005-06-01 00:00:00

abstract：:Sarcoidosis is an immune-mediated systemic syndrome of unknown etiology. The treatment of the granulomatous inflammation in sarcoidosis is thus dependent on nonspecific suppression of the immune response. Although steroid-sparing approaches have moved to front-line therapy for many other immune-mediated inflammatory d...

journal_title：Seminars in respiratory and critical care medicine

authors： Lazar CA,Culver DA

更新日期：2010-08-01 00:00:00

abstract：:Critical illness evoked by trauma, extensive surgery, or severe medical illnesses is the ultimate example of acute severe physical stress. The endocrine response in a critically injured and stressed patient is varied and complex. Although the acute and chronic phases of critical illness are characterized by distinct e...

journal_title：Seminars in respiratory and critical care medicine

authors： Raghavan M,Marik PE

更新日期：2006-06-01 00:00:00

abstract：:Tracheobronchial prostheses, known as airway stents, are used to palliate the effects of large airway obstruction. The most common types of stents in current clinical use are made of silicone or metallic wire. An ideal stent should possess several characteristics: (1) it should be easy to insert and remove, if necessa...

journal_title：Seminars in respiratory and critical care medicine

authors： Saito Y

更新日期：2004-08-01 00:00:00

abstract：:Pandemics of influenza have been reported since the early sixteenth century. Recent pandemics include the Spanish flu (H1N1) from 1918 to 1920 (resulting in approximately 50 million deaths worldwide); the Asian flu (H2N2) from 1957 to 1958 (resulting in more than 1 million deaths); the Hong Kong flu (H3N2) from 1968 t...

journal_title：Seminars in respiratory and critical care medicine

authors： Rajagopal S,Treanor J

更新日期：2007-04-01 00:00:00

abstract：:Nonspecific interstitial pneumonia (NSIP) represents one histologic subtype of idiopathic interstitial pneumonia (IIP). NSIP is typified by temporal homogeneity and less profusion of fibroblastic foci than is seen with usual interstitial pneumonia (UIP), the most common IIP. Clinically patients with NSIP present with ...

journal_title：Seminars in respiratory and critical care medicine

authors： Flaherty KR,Martinez FJ,Travis W,Lynch JP 3rd

更新日期：2001-08-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a common chronic autoimmune disorder that characteristically causes joint inflammation and damage. In addition, many patients develop extraarticular manifestations which may cause significant comorbidity and premature mortality.Some respiratory tract involvement of the upper and lower airw...

journal_title：Seminars in respiratory and critical care medicine

authors： Farquhar H,Vassallo R,Edwards AL,Matteson EL

更新日期：2019-04-01 00:00:00

abstract：:Patients admitted to the neuroscience intensive care unit (NICU) may have respiratory compromise from either central or peripheral neurological pathology, and may hence require intubation and mechanical ventilation for very diverse reasons. Liberation from invasive ventilation, that is, extubation, at the earliest pos...

journal_title：Seminars in respiratory and critical care medicine

authors： Bösel J

更新日期：2017-12-01 00:00:00