Clinical trial design in acute lung injury--issues and controversies.

abstract：:Massive pulmonary embolism (PE) refers to large emboli that cause hemodynamic instability, right ventricular failure, and circulatory collapse. According to the 2016 ACCP Antithrombotic Guidelines, therapy for massive PE should include systemic thrombolytic therapy in conjunction with anticoagulation and supportive ca...

journal_title：Seminars in respiratory and critical care medicine

authors： Weinberg A,Tapson VF,Ramzy D

更新日期：2017-02-01 00:00:00

abstract：:Practicing pulmonologists are often faced with the question of whether a lung disease is related to something in the patient's workplace, home, or recreational environment. Recognizing a lung disease as exposure related creates both opportunities and obligations for clinicians. In addition to managing the patient, the...

journal_title：Seminars in respiratory and critical care medicine

authors： Rose CS,Lynch DA,Cool CD

更新日期：2008-12-01 00:00:00

abstract：:Oral corticosteroids are powerful relatively nonspecific antiinflammatory agents with a range of well-characterized side effects. There is good evidence to show that they accelerate the rate of resolution of exacerbations of COPD and relapse is less likely if patients receive these drugs. Maintenance therapy with oral...

journal_title：Seminars in respiratory and critical care medicine

authors： Calverley PM

更新日期：2005-04-01 00:00:00

abstract：:Hematologic factors, in particular platelets and the coagulation system, play an important role in the pathogenesis of organ failure in the intensive care unit. Failure of these hematologic systems is common in intensive care patients and may range from isolated thrombocytopenia or prolonged global clotting tests to c...

journal_title：Seminars in respiratory and critical care medicine

authors： Levi M,Schultz M

更新日期：2011-10-01 00:00:00

abstract：:Pandemics of influenza have been reported since the early sixteenth century. Recent pandemics include the Spanish flu (H1N1) from 1918 to 1920 (resulting in approximately 50 million deaths worldwide); the Asian flu (H2N2) from 1957 to 1958 (resulting in more than 1 million deaths); the Hong Kong flu (H3N2) from 1968 t...

journal_title：Seminars in respiratory and critical care medicine

authors： Rajagopal S,Treanor J

更新日期：2007-04-01 00:00:00

abstract：:The vasculitides affecting large and medium-sized vessels are heterogeneous. This group includes such disorders as giant cell arteritis, Takayasu's disease, and sarcoidosis. There are several challenges that may arise in the care of patients with these disorders. Diagnosis may be elusive when initially evaluating pati...

journal_title：Seminars in respiratory and critical care medicine

authors： Maksimowicz-McKinnon K,Hoffman GS

更新日期：2004-10-01 00:00:00

abstract：:Pain is experienced by the overwhelming majority of patients during their intensive care unit stay, but it remains an underappreciated problem. To effectively treat pain, it must be detected and quantified using a validated assessment tool. It is acknowledged that optimal pain relief may be difficult to achieve given ...

journal_title：Seminars in respiratory and critical care medicine

authors： Joffe AM,Hallman M,Gélinas C,Herr DL,Puntillo K

更新日期：2013-04-01 00:00:00

abstract：:In endemic areas, dimorphic fungal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides posadasii/immitis account for up to 30% of cases of community-acquired pneumonia. Because respiratory manifestations are often indistinguishable from common bacterial causes of pneumonia, the diagnos...

journal_title：Seminars in respiratory and critical care medicine

authors： Azar MM,Malo J,Hage CA

更新日期：2020-08-01 00:00:00

abstract：:Sarcoidosis is by definition a disease of "unknown causes," but recent epidemiologic advances suggest that the long-standing definition of sarcoidosis may soon need to be amended. The recently completed ACCESS (A Case-Control Etiologic Study of Sarcoidosis) study was not able to definitively identify the "cause" of sa...

journal_title：Seminars in respiratory and critical care medicine

authors： Rybicki BA,Iannuzzi MC

更新日期：2007-02-01 00:00:00

abstract：:Tracheobronchial prostheses, known as airway stents, are used to palliate the effects of large airway obstruction. The most common types of stents in current clinical use are made of silicone or metallic wire. An ideal stent should possess several characteristics: (1) it should be easy to insert and remove, if necessa...

journal_title：Seminars in respiratory and critical care medicine

authors： Saito Y

更新日期：2004-08-01 00:00:00

abstract：:The elderly are especially prone to the adverse health effects of chronic obstructive pulmonary disease (COPD), which is a common disorder in that population. While the prevalence and morbidity of COPD in the elderly are high, it is often undiagnosed and thus undertreated. The diagnosis of COPD is primarily based on t...

journal_title：Seminars in respiratory and critical care medicine

authors： Hanania NA,Sharma G,Sharafkhaneh A

更新日期：2010-10-01 00:00:00

abstract：:Cryptococcosis is an invasive fungal infection (IFI), caused predominantly by Cryptococcus neoformans or Cryptococcus gattii, that affects both immunocompromised (IC) and non-IC patients. Although the most serious disease manifestation is meningoencephalitis, cryptococcal pneumonia is underdiagnosed and may disseminat...

journal_title：Seminars in respiratory and critical care medicine

authors： Brizendine KD,Baddley JW,Pappas PG

更新日期：2011-12-01 00:00:00

abstract：:Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common cardiovascular pathology after coronary disease and cerebrovascular diseases and is responsible for significant morbidity and mortality in the general population. Full-dose anticoagulation is the st...

journal_title：Seminars in respiratory and critical care medicine

authors： Imberti D,Maraldi C,Gallerani M

更新日期：2012-04-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is defined as a mean pulmonary artery pressure greater then 25 mm Hg at rest and greater then 30 mm Hg with exercise in association with normal left heart filling pressures. However, many patients with PAH have much higher pulmonary artery pressures, which, untreated, can rapidly ...

journal_title：Seminars in respiratory and critical care medicine

authors： Bull TM

更新日期：2005-08-01 00:00:00

abstract：:The purpose of this review is to familiarize a broad range of medical professionals with a relatively new and growing problem of infections caused by mycobacteria other than M. tuberculosis and M. leprae. There are at least 60 mycobacterial species that have been identified as causative agents of diseases in humans. T...

journal_title：Seminars in respiratory and critical care medicine

authors： Heifets L

更新日期：2004-06-01 00:00:00

abstract：:Pulmonary rehabilitation is a standard of care for patients with chronic lung disease. Through appropriate patient selection and assessment, exercise training, educational and psychosocial intervention, nutritional counseling, and breathing retraining, many benefits (e.g., reduction in level of dyspnea, improvement in...

journal_title：Seminars in respiratory and critical care medicine

authors： Carlin BW

更新日期：2009-12-01 00:00:00

abstract：:Critically ill intensive care unit (ICU) patients often require sedation to tolerate life-saving interventions such as mechanical ventilation. Pain, anxiety, and delirium all contribute to patient distress and agitation which can interfere with ICU medical care if not addressed and treated appropriately. Sedation prac...

journal_title：Seminars in respiratory and critical care medicine

authors： DeBiasi EM,Akgün KM,Pisani M

更新日期：2015-12-01 00:00:00

abstract：:Cor pulmonale frequently develops in patients with restrictive lung disease and neuromuscular disorders. Sleep disordered breathing, including nocturnal hypoventilation and obstructive apnea, has been associated with the development of cor pulmonale and may affect morbidity. The mechanisms responsible for sleep disord...

journal_title：Seminars in respiratory and critical care medicine

authors： Krachman SL,Criner GJ,Chatila W

更新日期：2003-06-01 00:00:00

abstract：:Sjögren syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic inflammation of exocrine glands and a variety of extraglandular sites. Lung involvement as defined by symptoms and either pulmonary function testing or radiographic abnormalities occurs in approximately 10 to 20% of patients. Subclinica...

journal_title：Seminars in respiratory and critical care medicine

authors： Kreider M,Highland K

更新日期：2014-04-01 00:00:00

abstract：:Despite significant progress in the field of transplant immunology, acute cellular rejection (ACR) remains a very frequent complication after lung transplantation (LTx), with almost 30% of LTx recipients experiencing at least one episode of treated ACR during the first year of follow-up. Most episodes respond to the f...

journal_title：Seminars in respiratory and critical care medicine

authors： Koutsokera A,Levy L,Pal P,Orchanian-Cheff A,Martinu T

更新日期：2018-04-01 00:00:00

abstract：:The human Herpesviridae family consists of eight members: cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus 1 and 2 (HSV-1, -2), varicella-zoster virus (VZV), and human herpesvirus 6, 7, and 8 (HHV-6, -7, -8). Lifelong latency may develop in the host with reactivation during periods of relative imm...

journal_title：Seminars in respiratory and critical care medicine

authors： Zamora MR

更新日期：2011-08-01 00:00:00

abstract：:Nonneoplastic pulmonary lymphoid disorders consist of a complex spectrum of diseases for pathologists and pulmonologists alike. Advances in our understanding of these disorders in recent years have led to revisions in the classification scheme. This review summarizes the clinicoradiological and pathological features o...

journal_title：Seminars in respiratory and critical care medicine

authors： Tian X,Yi ES,Ryu JH

更新日期：2012-10-01 00:00:00

abstract：:This review provides an update on literature published over the past 5 years that is relevant to using chest computed tomography (CT) as a tool for preventing occupational respiratory disease. An important area of investigation has been in the use of low-dose CT (LDCT) to screen asbestos-exposed populations for lung c...

journal_title：Seminars in respiratory and critical care medicine

authors： Weissman DN

更新日期：2015-06-01 00:00:00

abstract：:Ultrasonography of the thorax has become a more recognized tool in pulmonary medicine, thanks to continuing clinical research that has proven its many valuable roles in the day-to-day management of pulmonary and pleural diseases. Ultrasound examination is a cost-effective imaging modality that permits the pulmonologis...

journal_title：Seminars in respiratory and critical care medicine

authors： Shojaee S,Argento AC

更新日期：2014-12-01 00:00:00

abstract：:Paracoccidioidomycosis (formerly known as South American blastomycosis) is produced by the thermally dimorphic fungus Paracoccidioides brasiliensis. Most often this mycosis runs a chronic progressive course affecting preferentially the lungs followed by the skin, mucous membranes, adrenals, and reticuloendothelial org...

journal_title：Seminars in respiratory and critical care medicine

authors： Restrepo A,Benard G,de Castro CC,Agudelo CA,Tobón AM

更新日期：2008-04-01 00:00:00

abstract：:MYCOBACTERIUM AVIUM complex (MAC) consists of nontuberculous mycobacteria that cause disease in immunocompromised and immunocompetent hosts. The organisms are ubiquitous in the environment, and acquisition occurs through ingestion or inhalation of aerosols from soil, water, or biofilms. Disease may manifest as dissemi...

journal_title：Seminars in respiratory and critical care medicine

authors： Kasperbauer SH,Daley CL

更新日期：2008-10-01 00:00:00

abstract：:Pulmonary veno-occlusive disease (PVOD) is a rare disorder and can be misdiagnosed as idiopathic pulmonary arterial hypertension (iPAH). PVOD and iPAH often share a similar clinical presentation, genetic background, and hemodynamic profile. PVOD accounts for 5 to 10% of cases initially considered as iPAH. When compare...

journal_title：Seminars in respiratory and critical care medicine

authors： Montani D,Kemp K,Dorfmuller P,Sitbon O,Simonneau G,Humbert M

更新日期：2009-08-01 00:00:00

abstract：:This article discusses the pleural effusions that occur with the post-cardiac injury (Dressler's) syndrome (PCIS) and those that occur after coronary artery bypass graft (CABG) surgery. The PCIS can occur after any type of cardiac injury and is thought to be due to anti-myocardial antibodies. The primary symptoms are ...

journal_title：Seminars in respiratory and critical care medicine

authors： Light RW

更新日期：2001-12-01 00:00:00

abstract：:With the improving survival of cystic fibrosis (CF) patients and the advent of highly effective cystic fibrosis transmembrane conductance regulator therapy, the clinical spectrum of this complex multisystem disease continues to evolve. One of the most important clinical events for patients with CF in the course of thi...

journal_title：Seminars in respiratory and critical care medicine

authors： Goss CH

更新日期：2019-12-01 00:00:00

abstract：: ...

journal_title：Seminars in respiratory and critical care medicine

authors： Oh SS,Folch E

更新日期：2018-12-01 00:00:00