Abstract:
:The labelling of amoeboid microglial cells in the postnatal (2-10 days old) rat brain was studied by intracerebral injection of various lectins, including peroxidase-labelled Ricinus communis agglutinin (RCA), peroxidase-labelled isolectin Griffonia simplicifolia (GSA1-B4) and gold-labelled concanavalin A (Con A). Three to six hours after the injection of RCA and GSA1-B4, the amoeboid microglial cells in the supraventricular corpus callosum were selectively labelled. Most of the labelled cells were round, showing dense black reaction products. With the electron microscope the reaction of the binding sites for RCA and GSA1-B4 was localised on the plasma membrane, in the plasmalemmal invaginations, in the limiting membrane of the cytoplasmic vacuoles and in the dense granules identified as lysosomes. The binding sites for gold-labelled Con A were initially (one hour) observed at the plasma membrane. With time (3-6 hours) the gold particles occurred in the invaginations of the plasma membrane and consequently in the cytoplasmic vacuoles and in the dense granules. It appears therefore that the lectins first bind to their specific carbohydrate receptors on the plasma membrane and are later internalised by the cells. It is suggested that the receptors play an active role in phagocytic function. Furthermore, the fact that the amoeboid microglial cells show similar membrane lectin receptors as the monocyte-derived tissue macrophage supports the hypothesis of their origin from blood monocytes.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Kaur C,Ling EA,Wong WCsubject
Has Abstractpub_date
1990-12-01 00:00:00pages
151-60eissn
0021-8782issn
1469-7580journal_volume
173pub_type
杂志文章abstract::The moment arm of a muscle represents its leverage or torque-producing capacity, and is indicative of the role of the muscle in joint actuation. The objective of this study was to undertake a systematic review of the moment arms of the major muscles spanning the glenohumeral joint during abduction, flexion and axial r...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12903
更新日期:2019-01-01 00:00:00
abstract::Bundles of collagen fibrils, elastic fibres and fibroblasts are organized into a network that lies in the plane of a large portion of the bat wing. By ultrastructural (TEM and SEM) and biochemical analyses it was found that individual bundles of the net are similar to elastic ligaments. Although elastic fibres predomi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-05-01 00:00:00
abstract::The production of echolocation calls in bats along with forces produced by contraction of thoracic musculature used in flight presumably puts relatively high mechanical loads on the lower respiratory tract (LRT). Thus, there are likely adaptations to prevent collapse or distortion of the bronchial tree and trachea dur...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12575
更新日期:2017-04-01 00:00:00
abstract::Many studies have demonstrated the association between facet tropism and disc herniation in the lumbar spine. Some of them found that lumbar disc herniation was on the side of the more sagittal facet joint interface. However, little is understood about the association of facet tropism with disc herniation in the cervi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13151
更新日期:2020-05-01 00:00:00
abstract::As the uterus enlarges to accommodate the growing fetus during pregnancy, the cervix behaves essentially as a barrier. During ripening and delivery, it needs to become soft and distensible to allow dilation and the passage of the conceptus. As the transformations of the collagen-containing fibres are known to be essen...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00227.x
更新日期:2003-10-01 00:00:00
abstract::The labyrinth has two functional parts: the cochlea for audition and the vestibular system for equilibrioception. In the latter, the semicircular ducts and the otolithic organs are sensitive to rotational and linear accelerations of the head, respectively. The labyrinthine morphology influences perception accuracy, he...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12619
更新日期:2017-07-01 00:00:00
abstract::A quantitative analysis of the motor innervation of intrafusal muscle fibres is described, based on teased silver-impregnated spindles of the tenuissimus muscle of the cat. Included in the analysis are the number and distribution of intrafusal branches of both skeletofusimotor (beta) and purely fusimotor (gamma) axons...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
abstract::A defining feature of dentitions in modern sharks and rays is the regulated pattern order that generates multiple replacement teeth. These are arranged in labio-lingual files of replacement teeth that form in sequential time order both along the jaw and within successively initiated teeth in a deep dental lamina. Two ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12796
更新日期:2018-06-01 00:00:00
abstract::This study was prompted by the prospect of transgenic pigs providing donor hearts for transplantation in human recipients. Autonomic innervation is important for the control of cardiac dynamics, especially in the conduction system. Our objective was to assess the relative distribution of autonomic nerves in the pig he...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19530341.x
更新日期:1999-10-01 00:00:00
abstract::Langerhans cells of the epidermis of 6-month-old white crossbred farm pigs were identified by electron microscopy. Ultrastructurally they were similar to those described in other mammals. They were present in basal and suprabasal layers and were characterised by a lobulated nucleus and an electrolucent cytoplasm with ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::The frequency with which the gonadal arteries follow a recurrent course, upwards and arching over the renal veins before descending to the gonads, is recorded for the South African Negro. The gonadal arteries follow such a course on the left side in 17, 2% and on the right side in 22% of cases. This incidence for arch...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
abstract::The Harderian gland, its secretory duct and porphyrin content were examined in the mongolian gerbil (Meriones unguiculatus). The gland consisted of tubules lined by a single layer of epithelial cells and a myoepithelial network. The tubule cells were often binucleate and possessed lipid vacuoles in the apical half of ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract::The subglottic region of the larynx is of high clinical relevance with regard to infections and malignancies. Little is known about the distribution of mucins and antimicrobial substances in this area. In this study, we have investigated the mucin distribution in the normal subglottis of the larynx. Moreover, we analy...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00960.x
更新日期:2008-10-01 00:00:00
abstract::Videodigitised outlines of C6, C7, T1 and T2 vertebrae from 23 mice carrying the mutant gene undulated (un/un) and normal littermates (+/un) have been examined by Fourier analysis. There were large differences in shape between C6 vertebrae, smaller but significant differences in C7 and insignificant differences betwee...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::Alveolar macrophages were isolated from the lungs of hamsters by lavage and centrifugation. The harvesting procedure yielded about 5.2 X 10(6) cells per animal and the majority of these cells were viable as assessed by a Trypan blue exclusion test. Monolayers of macrophages were labelled with a series of FITC-conjugat...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::Three modes of construction of the rectus sheath above the arcuate line were found in a study of 40 cadavers. The classical description occurred most frequently, in 24 cases. The other constructions conformed to those described in earlier studies although the incidences were different. The accessory internal oblique m...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-04-01 00:00:00
abstract::Wheat germ agglutinin-horseradish peroxidase conjugate (WGA-HRP) was injected into the dorsal root ganglia (L5-S1) of the cat and used as an anterograde tracer substance for intra-axonal labelling of peripheral nerve endings in joint capsule and cranial (anterior) cruciate ligament (CCL). We believed that the high spe...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19020289.x
更新日期:1997-02-01 00:00:00
abstract::Mammalian pregnancy involves remodelling of the uterine epithelium to enable placentation. In marsupials, such remodelling has probably played a key role in the transition from ancestral invasive placentation to non-invasive placentation. Identifying uterine alterations that are unique to marsupials with non-invasive ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13162
更新日期:2020-06-01 00:00:00
abstract::Normal human kidneys were examined for the presence of granular peripolar cells. The prominent feature of the human peripolar cell was the presence of numerous cytoplasmic membrane-bound granules, which had the appearance of secretory granules. Most of the granules had a homogeneous matrix with no crystalline substruc...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-06-01 00:00:00
abstract::It is known that removal of one eye in the rat in early postnatal life results in an aberrant ipsilateral projection from the remaining eye. We have estimated the number of optic nerve fibres in 36 days old Black and White Hooded rats that had been unilaterally enucleated at birth. There was no significant difference ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract::Male rats undernourished from about birth until 100 days of age were nutritionally rehabilitated until 200 days. Six control and six experimental rats were anaesthetised and X-rayed at each of 50, 100 and 200 days. Measurements of various skeletal dimensions, and estimates of skeletal maturity, were made from these ra...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1985-08-01 00:00:00
abstract::This study examined NADPH-d and nNOS expression in the SCG of hamsters. By light microscopy, numerous NADPH-d/NOS positive processes were widely distributed in the ganglion. Ultrastructurally, the NADPH-d reaction product was associated with the membranous organelles of neuronal soma, dendrites, myelinated fibres, sma...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2000.19730461.x
更新日期:2000-10-01 00:00:00
abstract::Pulmonary alveolar septa are thought to contain at least two types of fibroblasts that are termed myofibroblasts and lipofibroblasts based on their morphological characteristics. Lipofibroblasts possess cytoplasmic lipid inclusions (lipid bodies or droplets) and are involved in several important functions, such as sur...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12677
更新日期:2017-12-01 00:00:00
abstract::The study of inborn genetic errors can lend insight into mechanisms of normal human development and congenital malformations. Here, we present the first detailed comparison of cranial and neuro pathology in two exceedingly rare human individuals with cyclopia and alobar holoprosencephaly (HPE) in the presence and abse...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12343
更新日期:2015-09-01 00:00:00
abstract::The three kinds of keratinized epithelium evident on gross examination of the soft palate of Wistar albino rats were studied by scanning and transmission electron microscopy. Scanning indicated a central area where the epithelium showed numerous fine folds and papillae, more lateral areas which were smooth, and most l...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::The present study investigated, by immunohistochemistry, the postnatal occurrence and anatomical localisation of some bone and cartilage proteins and proteoglycans in the rat coronal sutural region. Thirty two Sprague-Dawley rats, four in each group, were killed at ages 3, 5, 8, 10, 15, 30, 50 and 100 days and the sut...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract::The pituitary of roach, Rutilus rutilus (L.), is pear-shaped and situated in the sella turcica. It is characterised by a large pars nervosa, which penetrates deep into the other regions, splitting the proximal pars distalis. Spatial localisation of nerve fibre types and glandular cell types occurs. Using a variety of ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::There is evidence for lymphatic drainage of interstitial fluid from the brain along perivascular spaces in a number of mammalian species. Ultrastructural studies suggest that there are similar drainage pathways in the human cerebral cortex. Perivascular spaces in the basal ganglia, however, differ from those in the co...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19130337.x
更新日期:1997-10-01 00:00:00
abstract::Cellullar deficits are replenished within the central nervous system (CNS) by progenitors to maintain integrity and recover function after injury. NG2 proteoglycan-expressing progenitors replenish oligodendrocyte populations, but the nature of NG2 proteoglycan may not indicate a restricted population of progenitors. A...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2005.00480.x
更新日期:2005-12-01 00:00:00
abstract::Homoplastic grafts of re-orientated unsegmented paraxial mesoderm transplanted from stage 20 Xenopus embryos into host embryos of the same age resulted in segmentation and the formation of somites in the same axis as if they had been left in situ. Because grafts transplanted with various orientations came under the st...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00