Diuretic, natriuretic and hypotensive effects produced by Allium sativum (garlic) in anaesthetized dogs.

Abstract:

:Gastric administration of encapsuled garlic powder to anaesthetized dogs induced dose-dependent (2.5 to 15 mg/kg) natriuretic and diuretic responses which reached maximum 30-40 min after garlic administration and decreased to basal levels after 100-150 min. A simultaneous decrease in arterial blood pressure was observed which continued past the 250 min-mark. High garlic doses (15 and 20 mg/kg) provoked bradycardia and T-wave inversion during the first 10-15 min of the experiment with recordings returning to normal and staying normal throughout the remainder of the experiment.

journal_name

J Ethnopharmacol

authors

Pantoja CV,Chiang LC,Norris BC,Concha JB

doi

10.1016/0378-8741(91)90018-9

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

325-31

issue

3

eissn

0378-8741

issn

1872-7573

pii

0378-8741(91)90018-9

journal_volume

31

pub_type

杂志文章
  • β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The plant Arenaria kansuensis is used in traditional medicine to treat lung inflammation for a long time. However, the anti-pulmonary fibrosis effect and its corresponding bioactive constituents of this plant have not been studied extensively. AIM OF THE STUDY:The purpose of this study w...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.112096

    authors: Cui Y,Jiang L,Yu R,Shao Y,Mei L,Tao Y

    更新日期:2019-10-28 00:00:00

  • Evaluation of the wound-healing activity of selected traditional medicinal plants from Perú.

    abstract::Folk medicine practitioners in Perú employ plant preparations as wound-healing agents on superficial and internal wounds (gastric ulcers). The results of a scientific evaluation of the wound-healing activity of nine plants found in the Amazon jungle near Iquitos and in the Andes mountains is presented. The species stu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(96)01500-0

    authors: Villegas LF,Fernández ID,Maldonado H,Torres R,Zavaleta A,Vaisberg AJ,Hammond GB

    更新日期:1997-02-01 00:00:00

  • Lipidomics-based study on the neuroprotective effect of geissoschizine methyl ether against oxidative stress-induced cytotoxicity.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Lipid homoeostasis is important for neurodevelopment, cell signaling and neurotransmission. Alteration of lipid metabolism has been demonstrated in many neurological disorders and neurodegenerative diseases. Geissoschizine methyl ether (GM) is an active alkaloid ingredient in the traditio...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112636

    authors: Sun J,He F,Gao Y,Zhou Y,Zhang H,Huang M,Bi H

    更新日期:2020-05-10 00:00:00

  • Protective Effects of Pistacia lentiscus L. fruit extract against calcium oxalate monohydrate induced proximal tubular injury.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The world prevalence of kidney stones is increasing and plants are frequently used to treat urolithiasis. Pistacia lentiscus L, a plant which freely grows around the Mediterranean basin areas, is widely used for various pathologies. P. lentiscus has an important impact as it has economica...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.07.018

    authors: Cheraft-Bahloul N,Husson C,Ourtioualous M,Sinaeve S,Atmani D,Stévigny C,Nortier JL,Antoine MH

    更新日期:2017-09-14 00:00:00

  • Ginkgo biloba exocarp extracts inhibits angiogenesis and its effects on Wnt/β-catenin-VEGF signaling pathway in Lewis lung cancer.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:A fruit of Ginkgo biloba L. also known as Ginkgo biloba, can be used for the treatment of cancer in Chinese traditional medicine. The scientific name of succulent skin, which is the episperm of Ginkgo nuts, is exocarp. Experiment shows that Ginkgo biloba exocarp extracts (GBEE) has the ef...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.09.018

    authors: Han D,Cao C,Su Y,Wang J,Sun J,Chen H,Xu A

    更新日期:2016-11-04 00:00:00

  • Folk medical uses of plant foods in southern Appalachia, United States.

    abstract::An analysis of information obtained from interviews with 660 older native inhabitants of the southern Appalachian region in the United States indicates that plant foods, especially cultivars and materials processed from them, and some wildcrafted plant foods as well, constituted the bulk of the folk materia medica in ...

    journal_title:Journal of ethnopharmacology

    pub_type: 历史文章,杂志文章

    doi:10.1016/j.jep.2006.04.008

    authors: Cavender A

    更新日期:2006-11-03 00:00:00

  • Traditional uses of some medicinal plants in Malatya (Turkey).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:This study has identified not only the wild plants collected for medical purposes by local people of Malatya Province in the Eastern Anatolia Region, but also the uses and local names of these plants. It tried to provide a source for researchers studying in ethnobotany, pharmacology and c...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.12.054

    authors: Tetik F,Civelek S,Cakilcioglu U

    更新日期:2013-03-07 00:00:00

  • Screening for cytotoxic activity of plants used in traditional medicine.

    abstract::A total of 260 extracts have been prepared from 75 medicinal plant species collected in Africa, Panama and Mauritius. Three different concentrations of each extract have been screened in vitro for cytotoxic activity using a colorimetric assay to determine cell survival of human colon carcinoma Co115 cells. Fifteen pla...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(88)90006-2

    authors: Chapuis JC,Sordat B,Hostettmann K

    更新日期:1988-07-01 00:00:00

  • A traditional herbal formula, Hyangsa-Pyeongwi san (HPS), improves quality of life (QoL) of the patient with functional dyspepsia (FD): randomized double-blinded controlled trial.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Hyangaa-Pyeongwi san is the most well known description in Traditional Chinese Medicine for treating functional gastrointestinal disorders. Functional dyspepsia (FD) is a main concern of intimidating quality of life (QoL) in recent days. Although many medicines have been developed to impr...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jep.2013.10.033

    authors: Kim JB,Shin JW,Kang JY,Son CG,Kang W,Lee HW,Lee DS,Park YC,Cho JH

    更新日期:2014-01-01 00:00:00

  • The inhibitory effect of gypenoside stereoisomers, gypenoside L and gypenoside LI, isolated from Gynostemma pentaphyllum on the growth of human lung cancer A549 cells.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gypenosides are major constituents in Gynostemma pentaphyllum (Thunb.) Makino. Previous studies have shown that gypenosides isolated from G. pentaphyllum possess inhibitory effect on the growth of cancer cells, especially A549 cells, with structure-activity relationship (SAR). However, th...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2018.03.012

    authors: Xing SF,Liu LH,Zu ML,Ding XF,Cui WY,Chang T,Piao XL

    更新日期:2018-06-12 00:00:00

  • Anti-aromatase activity of the constituents from damiana (Turnera diffusa).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Damiana (Turnera diffusa Willd. Ex Schult) has traditionally been used as an herbal aphrodisiac. AIM OF THE STUDY:The study was aimed to investigate the anti-aromatse activity and the estrogenic activity of the constituents isolated from Turnera diffusa. MATERIALS AND METHODS:The methan...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2008.09.016

    authors: Zhao J,Dasmahapatra AK,Khan SI,Khan IA

    更新日期:2008-12-08 00:00:00

  • Poisonous delicacy: Market-oriented surveys of the consumption of Rhododendron flowers in Yunnan, China.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Plants from the family Ericaceae, and in particular those in the genus Rhododendron are frequently reported to contain grayanotoxins. Plant products such as honey and herbal medicines made from these plants occasionally contain grayanotoxins, and in turn may lead to intoxication. The bala...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113320

    authors: Shi Y,Zhou M,Zhang Y,Fu Y,Li J,Yang X

    更新日期:2021-01-30 00:00:00

  • In vivo antimalarial activities of extracts from Amaranthus spinosus L. and Boerhaavia erecta L. in mice.

    abstract::Extracts obtained from two Burkinabe folk medicine plants, spiny amaranth (Amaranthus spinosus L., Amaranthaceae) and erect spiderling (Boerhaavia erecta L., Nyctagynaceae) were screened for antimalarial properties with the aim of testing the validity of their traditional uses. The plant extracts showed significant an...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.08.006

    authors: Hilou A,Nacoulma OG,Guiguemde TR

    更新日期:2006-01-16 00:00:00

  • The plasma glucose lowering action of Hei-Shug-Pian, the fire-processed product of the root of Aconitum (Aconitum carmichaeli), in streptozotocin-induced diabetic rats.

    abstract::The anti-hyperglycemic action of Hei-Shug-Pian, the fire-processed product of the root of Aconitum (Aconitum carmichaeli), was investigated in streptozotocin-induced diabetic (STZ-diabetic) rats. At 120 min following oral administration of Hei-Shug-Pian at doses ranging from 12.5 to 50 mg/kg, plasma glucose of STZ-dia...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2006.01.001

    authors: Liou SS,Liu IM,Lai MC

    更新日期:2006-06-30 00:00:00

  • An integrated study of metabolomics and transcriptomics to reveal the anti-primary dysmenorrhea mechanism of Akebiae Fructus.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Akebiae Fructus, a Tujia minority folk medicine and a well-known traditional Chinese medicine for soothing the liver, regulating Qi, promoting blood circulation and relieving pain, is widely used in the treatment of primary dysmenorrhea. However, little is known about its underlying mecha...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113763

    authors: Ma B,Yang S,Tan T,Li J,Zhang X,Ouyang H,He M,Feng Y

    更新日期:2020-12-28 00:00:00

  • Antinociceptive and anti-inflammatory effects of Dorstenia barteri (Moraceae) leaf and twig extracts in mice.

    abstract::The present study was undertaken to investigate the antinociceptive and anti-inflammatory activities of the leaf and twig extracts of Dorstenia barteri (Moraceae) in mice. Both the leaf and twig extracts of Dorstenia barteri at 50, 100 and 200 mg/kg showed significant (P < 0.05-0.01) antinociceptive activities in chem...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2004.05.022

    authors: Omisore NO,Adewunmi CO,Iwalewa EO,Ngadjui BT,Watchueng J,Abegaz BM,Ojewole JA

    更新日期:2004-11-01 00:00:00

  • Saussurea costus: botanical, chemical and pharmacological review of an ayurvedic medicinal plant.

    abstract::Saussurea costus (Falc.) Lipschitz, syn Saussurea lappa C.B. Clarke is a well known and important medicinal plant widely used in several indigenous systems of medicine for the treatment of various ailments, viz. asthma, inflammatory diseases, ulcer and stomach problems. Sesquiterpene lactones have been reported as the...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2006.12.033

    authors: Pandey MM,Rastogi S,Rawat AK

    更新日期:2007-04-04 00:00:00

  • The knowledge of medicinal plants in Africa today.

    abstract::The oral tradition for communication in Africa is stressed as well as the secrecy of the treatments with plants by traditional medicine-men. This makes it difficult to obtain more exact information on all the different aspects of traditional medicine. Nevertheless, some data have been collected in the Francophone coun...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(80)90022-7

    authors: Lantum DN

    更新日期:1980-03-01 00:00:00

  • Antibiotic screening of medicinal plants of the British Columbian native peoples.

    abstract::One hundred methanolic plant extracts, 96 of which had documented medicinal uses by British Columbian native peoples, were screened for antibiotic activity against 11 bacterial strains. Eighty-five percent were found to have significant antibiotic activity against at least two of the bacteria tested. Ninety-five perce...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(92)90036-q

    authors: McCutcheon AR,Ellis SM,Hancock RE,Towers GH

    更新日期:1992-10-01 00:00:00

  • The taste of heat: How humoral qualities act as a cultural filter for chemosensory properties guiding herbal medicine.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Organoleptic properties, and more specifically chemosensory cues, have been shown to guide therapeutic applications of medicinal plants. Humoral qualities, on the other hand, are widely believed to be an abstract concept, mainly applied post hoc to validate therapy. However, the nexus bet...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.01.027

    authors: Geck MS,Cabras S,Casu L,Reyes García AJ,Leonti M

    更新日期:2017-02-23 00:00:00

  • Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice.

    abstract::The effects of daily administration of Withania somnifera root extract (1.4 g/kg body wt.) and Bauhinia purpurea bark extract (2.5 mg/kg body wt.) for 20 days on thyroid function in female mice were investigated. While serum triiodothyronine (T3) and thyroxine (T4) concentrations were increased significantly by Bauhin...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(99)00018-5

    authors: Panda S,Kar A

    更新日期:1999-11-01 00:00:00

  • In vitro and in vivo anti-hepatitis B virus activities of the lignan nirtetralin B isolated from Phyllanthus niruri L.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Nirtetralin B, a new lignan first reported by our team, is isolated from Phyllanthus niruri L. This plant has long been used in folk medicine for liver protection and antihepatitis B in many Asian countries. This study was designed to evaluate the anti-hepatitis B virus activity of nirtet...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.09.019

    authors: Liu S,Wei W,Li Y,Lin X,Shi K,Cao X,Zhou M

    更新日期:2014-11-18 00:00:00

  • Subchronic toxicological evaluation of Bojungikki-tang water extract: 13-Week oral repeated-dose toxicity study in Crl:CD (SD) rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Bojungikki-tang is a traditional herbal medicine used to boost immunity and reduce fatigue. However, there is not enough scientific evidence about its toxicological safety profile to support its continued clinical application. AIM OF THE STUDY:The objective of this study was to investiga...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112551

    authors: Jeon WY,Seo CS,Ha H,Shin HK,Cho JW,Kim DH,Lee MY

    更新日期:2020-04-24 00:00:00

  • Nitrites and nitrates in the human diet: Carcinogens or beneficial hypotensive agents?

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The presence of nitrite in the human diet was thought to constitute a hazard as secondary nitrosamines are known to cause gastric cancers. MATERIALS AND METHODS:Recent publications on the physiology of serum nitrite have been consulted. PROBLEMS:Nitrite is added to some foodstuffs as an...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.09.040

    authors: Butler A

    更新日期:2015-06-05 00:00:00

  • Effects of alkaloids of Himatanthus lancifolius (Muell. Arg.) Woodson, Apocynaceae, on smooth muscle responsiveness.

    abstract::Himatanthus lancifolius, popularly known as "agoniada" in Brazil, is largely used in folk medicine against asthma, dysmenorrhea and as an emenagogue and abortive. This study reveals the effects of an alkaloid rich fraction (AlkF) obtained from the bark of Himatanthus lancifolius in vascular and non-vascular smooth mus...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.02.041

    authors: Rattmann YD,Terluk MR,Souza WM,Santos CA,Biavatti MW,Torres LB,Mesia-Vela S,Rieck L,da Silva-Santos JE,Marques MC

    更新日期:2005-09-14 00:00:00

  • Ethnobotanical survey in the Palestinian area: a classification of the healing potential of medicinal plants.

    abstract::An ethnobotanical survey was carried out in the West Bank to evaluate the relative efficacy of the plants used to treat skin diseases and prostate cancer. A total number of 102 informants, 30 years and older and either native born or had been living in the West Bank for more than 30 years, were interviewed using a pre...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(00)00316-0

    authors: Ali-Shtayeh MS,Yaniv Z,Mahajna J

    更新日期:2000-11-01 00:00:00

  • Improvement in mitochondrial function underlies the effects of ANNAO tablets on attenuating cerebral ischemia-reperfusion injuries.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:ANNAO tablets derive from Chinese classical prescriptions of Angong Niuhuang Pills with modified compositions, which have been singly or combined used for stoke associated neurological disorders. However the underlying mechanism is not yet well-defined, the present study investigated its ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.112212

    authors: Zhang Y,Cao M,Wu Y,Wang J,Zheng J,Liu N,Yang N,Liu Y

    更新日期:2020-01-10 00:00:00

  • Exploration of the potential mechanism of the Tao Hong Si Wu Decoction for the treatment of postpartum blood stasis based on network pharmacology and in vivo experimental verification.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Tao Hong Si Wu Decoction (THSWD) is a traditional prescription for blood management in traditional Chinese medicine, THSWD consists of Paeoniae Radix Alba (Paeonia lactiflora Pall.), Rehmanniae Radix Praeparata (Rehmannia glutinosa (Gaertn.) DC.), Angelicae Sinensis Radix (Angelica sinens...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113641

    authors: Xia W,Hu S,Wang M,Xu F,Han L,Peng D

    更新日期:2021-03-25 00:00:00

  • Pharmacological effects of lavandulifolioside from Leonurus cardiaca.

    abstract::Lavandulifolioside was detected for the first time in Leonurus cardiaca var. vulgaris [Moench] Briquet (Lamiaceae). The isolation was performed from the butanolic extract of the aerial parts and the identification by NMR and MS. The pharmacological properties of lavandulifolioside consist of significant negative chron...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(02)00016-8

    authors: Miłkowska-Leyck K,Filipek B,Strzelecka H

    更新日期:2002-04-01 00:00:00

  • Antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Arctium lappa and Tussilago farfara (Asteraceae) are two plant species used traditionally as antitubercular remedies. The aim of this study was (i) to screen Arctium lappa and Tussilago farfara extracts for activity against Mycobacterium tuberculosis and (ii) to isolate and identify the c...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.06.034

    authors: Zhao J,Evangelopoulos D,Bhakta S,Gray AI,Seidel V

    更新日期:2014-08-08 00:00:00