Pharmacological effects of lavandulifolioside from Leonurus cardiaca.

Abstract:

:Lavandulifolioside was detected for the first time in Leonurus cardiaca var. vulgaris [Moench] Briquet (Lamiaceae). The isolation was performed from the butanolic extract of the aerial parts and the identification by NMR and MS. The pharmacological properties of lavandulifolioside consist of significant negative chronotropism, prolongation of the P-Q, Q-T intervals and QRS complex, and decrease of blood pressure. Contrary to the butanolic extract lavandulifolioside did not reduce the spontaneous locomotor activity. In conclusion, the pharmacological pattern of lavandulifolioside did not explain the pharmacological effects of L. cardiaca L. alone.

journal_name

J Ethnopharmacol

authors

Miłkowska-Leyck K,Filipek B,Strzelecka H

doi

10.1016/s0378-8741(02)00016-8

keywords:

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

85-90

issue

1

eissn

0378-8741

issn

1872-7573

pii

S0378874102000168

journal_volume

80

pub_type

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