The consistency of pulse frequencies and pulse patterns of transcutaneous electrical nerve stimulation (TENS) used by chronic pain patients.

abstract：:Pain is processed in multiple cortical and subcortical brain areas. Subcortical structures are substantially involved in different processes that are closely linked to pain processing, e.g. motor preparation, autonomic responses, affective components and learning. However, it is unclear to which extent nociceptive inf...

journal_title：Pain

authors： Bingel U,Quante M,Knab R,Bromm B,Weiller C,Büchel C

更新日期：2002-09-01 00:00:00

abstract：:Chronic pain is more common in the elderly and impairs functioning and quality of life. Though obesity, defined by body mass index (BMI), has been associated with pain prevalence among older adults, the mechanism of this association remains unclear. We examined components of the metabolic syndrome, insulin resistance,...

journal_title：Pain

authors： Ray L,Lipton RB,Zimmerman ME,Katz MJ,Derby CA

更新日期：2011-01-01 00:00:00

abstract：:Eight patients with established lower limb postamputation stump pain were given lumbar intrathecal fentanyl 25 micrograms and lidocaine 70 mg 2 weeks apart in an attempt to better understand the role of peripheral and central mechanisms in this condition. Baseline pain was recorded and then analgetic and side effects ...

journal_title：Pain

authors： Jacobson L,Chabal C,Brody MC,Mariano AJ,Chaney EF

更新日期：1990-02-01 00:00:00

abstract：:A 78-year-old male patient had chronic, unrelieved abdominal pain due to mesenteric ischaemia. Unsuccessful pharmacological approaches included oral morphine plus coadjuvants as well as a sympathetic celiac plexus block which gave pain relief that lasted for 72 h. In order to obtain long-lasting relief, a trial epidur...

journal_title：Pain

authors： Ceballos A,Cabezudo L,Bovaira M,Fenollosa P,Moro B

更新日期：2000-07-01 00:00:00

abstract：:Fear-avoidance beliefs have been identified as an important psychosocial variable in patients with chronic disability doe to low back pain. The importance of fear-avoidance beliefs for individuals with acute low back pain has not been explored. Seventy-eight subjects with work-related low back pain of less than 3 week...

journal_title：Pain

authors： Fritz JM,George SZ,Delitto A

更新日期：2001-10-01 00:00:00

abstract：:P2X3 purinoceptor cellular distribution was studied in rat sensory neurons in naive animals and following peripheral nerve injury using immunohistochemical methods. Specific antiserum was raised in rabbits and characterized by Western blot, absorption assays and labeling of recombinant receptors. In naive animals, P2X...

journal_title：Pain

authors： Novakovic SD,Kassotakis LC,Oglesby IB,Smith JA,Eglen RM,Ford AP,Hunter JC

更新日期：1999-03-01 00:00:00

abstract：:Accurate pain assessment is the foundation for effective pain management in children. At present, there is no clear consensus regarding the age at which young children are able to appropriately use self-report scales for pain. This study examined young children's ability to use the Faces Pain Scale-Revised; (FPS-R; [H...

journal_title：Pain

authors： Stanford EA,Chambers CT,Craig KD

更新日期：2006-01-01 00:00:00

abstract：:The redefinition of neuropathic pain as "pain arising as a direct consequence of a lesion or disease affecting the somatosensory system," which was suggested by the International Association for the Study of Pain (IASP) Special Interest Group on Neuropathic Pain (NeuPSIG) in 2008, has been widely accepted. In contrast...

journal_title：Pain

authors： Finnerup NB,Haroutounian S,Kamerman P,Baron R,Bennett DLH,Bouhassira D,Cruccu G,Freeman R,Hansson P,Nurmikko T,Raja SN,Rice ASC,Serra J,Smith BH,Treede RD,Jensen TS

更新日期：2016-08-01 00:00:00

abstract：:Quantitative sensory testing (QST) in accordance with the DFNS (German Research Network on Neuropathic Pain) protocol assesses the function of afferent nerve fibers on the basis of 13 parameters. Within the consortia IMI (Innovative Medicines Initiative) Europain and Neuropain, QST results from pain research units exp...

journal_title：Pain

authors： Vollert J,Attal N,Baron R,Freynhagen R,Haanpää M,Hansson P,Jensen TS,Rice ASC,Segerdahl M,Serra J,Sindrup SH,Tölle TR,Treede RD,Maier C

更新日期：2016-03-01 00:00:00

abstract：:Theoretical models and evidence increasingly identify chronic pain as a family issue. To date, much of this work has focused on risk conferred by parental chronic pain status despite evidence suggesting parent mental illness and non-pain-related chronic illness may also contribute to poorer chronic pain outcomes in ch...

journal_title：Pain

authors： Birnie KA,Heathcote LC,Bhandari RP,Feinstein A,Yoon IA,Simons LE

更新日期：2020-06-01 00:00:00

abstract：:The goal of this study was to develop and validate a self-completed questionnaire, the Fibromyalgia Rapid Screening Tool (FiRST), for the detection of fibromyalgia syndrome in patients with diffuse chronic pain. Items requiring "yes/no" responses and relating to the most relevant clinical characteristics of fibromyalg...

journal_title：Pain

authors： Perrot S,Bouhassira D,Fermanian J,CEDR (Cercle d'Etude de la Douleur en Rhumatologie).

更新日期：2010-08-01 00:00:00

abstract：:The pathophysiology of burning mouth syndrome (BMS) is largely unknown. Thus, the aim was to study oral mucosal blood flow in BMS-patients using laser Doppler flowmetry (LDF). Thirteen BMS patients (11 female, two male; mean age+/-SD 64.3+/-7.9 years, mean disease duration 18.9+/-6.2 months) and 13 healthy non-smoking...

journal_title：Pain

authors： Heckmann SM,Heckmann JG,HiIz MJ,Popp M,Marthol H,Neundörfer B,Hummel T

更新日期：2001-02-15 00:00:00

abstract：:A systematic review and meta-analysis of population-based epidemiological studies was undertaken to determine the prevalence of foot and ankle pain in middle and old age. Searches were conducted in the following electronic databases from inception to October 2010: PubMed, EMBASE, AMED, CINAHL, Cochrane, PEDro, and Spo...

journal_title：Pain

authors： Thomas MJ,Roddy E,Zhang W,Menz HB,Hannan MT,Peat GM

更新日期：2011-12-01 00:00:00

abstract：:Hindlimb pain models developed in rats have been transposed to mice, but assumed sciatic nerve neuroanatomic similarities have not been examined. We compared sciatic nerve structural organization in mouse strains (C57BL/6J, DBA/2J, and B6129PF2/J) and rat strains (Wistar, Brown Norway, and Sprague-Dawley). Dissection ...

journal_title：Pain

authors： Rigaud M,Gemes G,Barabas ME,Chernoff DI,Abram SE,Stucky CL,Hogan QH

更新日期：2008-05-01 00:00:00

abstract：:Extracellular signal-regulated kinase (ERK), a mitogen-activated protein kinases (MAPK), transduces a broad range of extracellular stimuli into diverse intracellular responses. Recent studies have showed that ERK activation in the supraspinal level involved in the development of drug dependence, especially in psycholo...

journal_title：Pain

authors： Cao JL,He JH,Ding HL,Zeng YM

更新日期：2005-12-05 00:00:00

abstract：:Constipation is the most common adverse event (AE) of opioid therapy. This multicenter, phase 2 study evaluated the efficacy and safety of linaclotide in treating opioid-induced constipation (OIC) in patients with chronic noncancer pain syndromes (NCT02270983). Adults with OIC (<3 spontaneous bowel movements [SBMs]/we...

journal_title：Pain

authors： Brenner DM,Argoff CE,Fox SM,Bochenek W,D'Astoli P,Blakesley RE,Reasner DS,O'Dea CR,Cash BD

更新日期：2020-05-01 00:00:00

abstract：:To investigate the pathways of noxious information in the spinal cord in humans, we recorded cortical potentials following the stimulation of A-delta fibers using a YAG laser applied to two cutaneous points on the back at the C7 and Th10 level, 4cm to the right of the vertebral spinous process. A multiple source analy...

journal_title：Pain

authors： Tsuji T,Inui K,Kojima S,Kakigi R

更新日期：2006-08-01 00:00:00

abstract：:In this study, construct validity of 2 pain behaviour observation measurement instruments for young children aged 1 to 56 months (mean age was 20 months) with burns is assessed by using Rasch analysis. The Rasch model, wherein data should meet the model expectations, assumes that an instrument measures one unidimensio...

journal_title：Pain

authors： de Jong AEE,Tuinebreijer WE,Bremer M,van Komen R,Middelkoop E,van Loey N

更新日期：2012-11-01 00:00:00

abstract：:In the last decade, there has been burgeoning interest in the effectiveness of third-generation psychological therapies for managing fibromyalgia (FM) symptoms. The present study examined the effectiveness of acceptance and commitment therapy (ACT) on functional status as well as the role of pain acceptance as a media...

journal_title：Pain

authors： Luciano JV,Guallar JA,Aguado J,López-Del-Hoyo Y,Olivan B,Magallón R,Alda M,Serrano-Blanco A,Gili M,Garcia-Campayo J

更新日期：2014-04-01 00:00:00

abstract：:Anxiety is almost inevitably present in patients facing surgery. The optimal management of postoperative pain requires the acknowledgement of perioperative anxiety and the inclusion of pharmacological and/or non-pharmacological means of alleviating the fear and worry inherent in the surgical experience. In a double-bl...

journal_title：Pain

authors： Egan KJ,Ready LB,Nessly M,Greer BE

更新日期：1992-04-01 00:00:00

abstract：:Regular physical activity in healthy individuals prevents development of chronic musculoskeletal pain; however, the mechanisms underlying this exercise-induced analgesia are not well understood. Interleukin-10 (IL-10), an antiinflammatory cytokine that can reduce nociceptor sensitization, increases during regular phys...

journal_title：Pain

authors： Leung A,Gregory NS,Allen LH,Sluka KA

更新日期：2016-01-01 00:00:00

abstract：:The GABA(B) receptor-mediated presynaptic inhibition of glycinergic transmission was studied from young rat substantia gelatinosa (SG) neurons using a conventional whole-cell patch clamp technique. Action potential-dependent glycinergic inhibitory postsynaptic currents (IPSCs) were recorded from SG neurons in the pres...

journal_title：Pain

authors： Choi IS,Cho JH,Jeong SG,Hong JS,Kim SJ,Kim J,Lee MG,Choi BJ,Jang IS

更新日期：2008-08-31 00:00:00

abstract：:Percentage of pain intensity difference (PercentPID) is a recognized way of evaluating pain relief with an 11-point numerical rating scale (NRS) but is not without flaws. A new metric, the slope of relative pain intensity difference (SlopePID), which consists in dividing PercentPID by the time between 2 pain measureme...

journal_title：Pain

authors： Chauny JM,Paquet J,Lavigne G,Marquis M,Daoust R

更新日期：2016-02-01 00:00:00

abstract：:Animal studies have suggested that the cerebellum, in addition to its motor functions, also has a role in pain processing and modulation, possibly because of its extensive connections with the prefrontal cortex and with brainstem regions involved in descending pain control. Consistently, human imaging studies have sho...

journal_title：Pain

authors： Ruscheweyh R,Kühnel M,Filippopulos F,Blum B,Eggert T,Straube A

更新日期：2014-07-01 00:00:00

abstract：:Mechanical allodynia is pain caused by normally innocuous mechanical stimuli and is a cardinal and intractable symptom of neuropathic pain. Roles of low-threshold mechanoreceptors (LTMRs), including Aβ fibers, in mechanical allodynia have previously been proposed, but the necessity and sufficiency of LTMRs in allodyni...

journal_title：Pain

authors： Tsuda M

更新日期：2019-05-01 00:00:00

abstract：:Psychologic assessment and treatment of the family of the chronic pain patient has been thought to be of benefit in the outcome of pain therapy. The present study was designed to determine the presence of psychologic symptoms in the spouses of pain patients and the relationship of distress levels between the marital p...

journal_title：Pain

authors： Shanfield SB,Heiman EM,Cope N,Jones JR

更新日期：1979-12-01 00:00:00

abstract：:We have examined the effects of cannabinoid agonists on hyperalgesia in a model of neuropathic pain in the rat and investigated the possible sites of action. The antihyperalgesic activity of the cannabinoids was compared with their ability to elicit behavioural effects characteristic of central cannabinoid activity. W...

journal_title：Pain

authors： Fox A,Kesingland A,Gentry C,McNair K,Patel S,Urban L,James I

更新日期：2001-05-01 00:00:00

abstract：:The M-current has been proposed as a potential target for analgesia under neuropathic pain conditions. M-currents and/or their molecular correlates, KCNQ proteins, have been demonstrated in key elements of the nociceptive system including spinal and dorsal root ganglion neurons. Here we demonstrate that retigabine, a ...

journal_title：Pain

authors： Roza C,Lopez-Garcia JA

更新日期：2008-09-15 00:00:00

abstract：:Though it is clear that genomic variability plays an integral role in accounting for pain sensitivity, controversy exists over which genes are involved. While recent data suggest a "protective" (i.e., less pain) haplotype in the GTP cyclohydrolase (GCH1) gene, other research has failed to confirm this association. Pos...

journal_title：Pain

authors： Campbell CM,Edwards RR,Carmona C,Uhart M,Wand G,Carteret A,Kim YK,Frost J,Campbell JN

更新日期：2009-01-01 00:00:00

abstract：:The effects of lateral reticular nucleus (LRN) stimulation on the responses to tooth pulp (TP) stimulation of neurons located in the trigeminal (V) sensory (39 units) and motor (33 units) nuclei were assessed in anesthetized rats. Only neurons which responded to TP stimulation with bursts of spikes that were in a cons...

journal_title：Pain

authors： Sotgiu ML,Bellinzona M

更新日期：1991-07-01 00:00:00