Tumefactive intracranial presentation of precursor B-cell acute lymphoblastic leukemia.

Abstract:

:In children, leukemia is the most common malignancy, and approximately 75% of leukemias are acute lymphoblastic leukemia (ALL). Central nervous system leukemia is found at diagnosis in fewer than 5% of children with ALL. Leukemic intracranial masses have been described with acute myeloid leukemia, but ALL presenting as a mass lesion is rare. We describe a unique case of an intracranial confirmed precursor B cell (pre-B) ALL mass in a 13-year-old girl that was diagnosed by brain CT, MRI and cerebral angiography, and confirmed by biopsy. This report details pertinent history and distinguishing imaging features of an intracranial ALL tumefaction.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Forester CM,Braunreiter CL,Yaish H,Hedlund GL,Afify Z

doi

10.1007/s00247-009-1347-x

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

1230-3

issue

11

eissn

0301-0449

issn

1432-1998

journal_volume

39

pub_type

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