Abstract:
BACKGROUND:Because of its absence of ionising radiation and possibility for obtaining functional information, MRI is promising for assessing lung disease in children who require repetitive imaging for long-term follow-up. OBJECTIVE:To describe MRI findings in children with cystic fibrosis and evaluate semi-quantitative dynamic contrast-enhanced lung perfusion. MATERIALS AND METHODS:We retrospectively compared lung MRI in 25 children and young adults with cystic fibrosis (median age 3.7 years) to 12 children (median age 2 years) imaged for other pathologies. MRI at 1.5 T included respiratory-gated sequences and contrast-enhanced lung perfusion imaging. We described and graded any morphologic change. Signal enhancement and time to peak values of perfusion abnormalities were compared to those of normally enhancing lung parenchyma. RESULTS:Frequent findings in patients with cystic fibrosis were bronchial wall thickening (24/25, 96%), areas of consolidation (22/25, 88%), enlarged lymph nodes (20/25, 80%), bronchiectasis (5/25, 20%) and mucus plugging (3/25, 12%). Compared to normally enhancing lung, perfusion defects (21/25, 84%), characterised by decreased enhancement, showed prolonged time to peak. Areas of consolidation showed increased enhancement. While time to peak of procedure-related atelectasis was not significantly different from that of normal lung, disease-related consolidation showed prolonged time to peak (P=0.01). CONCLUSION:Lung MRI demonstrates structural and perfusion abnormalities in children and young people with cystic fibrosis. Semi-quantitative assessment of dynamic contrast-enhanced perfusion imaging might allow differentiation between procedure-related atelectasis and disease-related consolidation.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Amaxopoulou C,Gnannt R,Higashigaito K,Jung A,Kellenberger CJdoi
10.1007/s00247-017-4021-8subject
Has Abstractpub_date
2018-02-01 00:00:00pages
165-175issue
2eissn
0301-0449issn
1432-1998pii
10.1007/s00247-017-4021-8journal_volume
48pub_type
杂志文章abstract::This paper compares the effects on patients of perforation with barium and with air during attempted intussusception reduction by reviewing the clinical, radiological, surgical and pathological findings and sequelae in seven children who received barium and seven who received air. In both groups perforation occurred i...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02010311
更新日期:1995-01-01 00:00:00
abstract::Primary aldosteronism in children under 16 years of age is usually due to adrenal hyperplasia. We could find only seven cases in the literature where it was caused by a solitary adrenal adenoma; all but one were female. We describe the case of a 10-year-old Caucasian boy in whom a unilateral adrenal adenoma was demons...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02387519
更新日期:1986-01-01 00:00:00
abstract::A case of pyelocalyceal diverticula in a patient with the Beckwith-Wiedemann syndrome is presented. The abnormalities were first identified on screening ultrasound and confirmed at excretory urography. The diverticula in this syndrome are likely secondary to hereditary embryopathy of the kidneys. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02386605
更新日期:1987-01-01 00:00:00
abstract::We present a 15-year-old girl with peritoneal metastases from a solid pseudopapillary tumour of the pancreas, which had been excised 6 years previously. This is the third paediatric case with metastases to be reported and the fourth patient with peritoneal carcinomatosis. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-003-0875-z
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Massive ovarian edema is a rare benign condition that predominantly affects childbearing women as well as preadolescent girls. It is thought to result from intermittent or partial torsion of the ovary compromising the venous and lymphatic drainage but with preserved arterial supply. The clinical features of ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-017-3782-4
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Typical flow velocity profiles in the extraparenchymal pulmonary veins (PVs) demonstrate two major antegrade flow waves: a biphasic systolic wave (S), with S1 and S2 peaks and a monophasic early diastolic wave (D). Flow reversal during atrial systole (A) is common. There is agreement that the forward diastol...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2227-8
更新日期:2012-02-01 00:00:00
abstract::Venous drainage to the portal vein in pulmonary sequestration is rare. A 7-month-old girl was referred to our hospital following surgery for ventricular septal defect because of a left upper abdominal mass with a large feeding artery from the abdominal aorta and venous drainage to the portal vein. She had had frequent...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000251
更新日期:2000-07-01 00:00:00
abstract::Part 1 of this series of two articles describes conventional and advanced MRI techniques that are useful for evaluating brainstem pathologies. In addition, it provides a review of the embryology, normal progression of myelination, and clinically and radiologically salient imaging anatomy of the normal brainstem. Final...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-020-04954-0
更新日期:2021-02-01 00:00:00
abstract::Pediatric cancers often have specific molecular fingerprints making them primary candidates for the development of targeted imaging techniques. Tumor-targeted tracers have the potential to substantially advance the sensitivity and specificity of imaging techniques by improving tumor detection and characterization. Thi...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-008-0878-x
更新日期:2008-11-01 00:00:00
abstract::Hyperthyroidism occurs secondary to overproduction of thyroid hormone by the thyroid gland. This condition can have rather serious effects on children, and thus timely diagnosis and treatment are of utmost importance. Imaging is quite useful in the management of children with hyperthyroidism. In addition to determinin...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-013-2707-0
更新日期:2013-10-01 00:00:00
abstract::We present a child with double aberrant left brachiocephalic vein (ALBCV) that was an incidental finding on CT. The anterior and thin branch was above the aortic arch and behind the truncus brachiocephalicus and drained into the superior vena cava (SVC). The posterior and thick branch of the ALBCV coursed posterior to...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-007-0663-2
更新日期:2008-03-01 00:00:00
abstract::Despite the availability of Doppler ultrasound, angiography still forms part of the protocol for evaluating children after orthotopic liver transplantation (OLT) at our department. To investigate whether Doppler ultrasound is a reliable method for evaluating the patency of the hepatic artery, portal vein, inferior ven...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02015783
更新日期:1995-01-01 00:00:00
abstract::Neonatal cerebral MR imaging is a sensitive technique for evaluating brain injury in the term and preterm infant. In term encephalopathic infants, MR imaging reliably detects not only the pattern of brain injury but might also provide clues about the timing of injury. In premature infants, MR imaging has surpassed US ...
journal_title:Pediatric radiology
pub_type: 杂志文章,实务指引
doi:10.1007/s00247-007-0705-9
更新日期:2008-03-01 00:00:00
abstract::Following bacterial meningitis thirty cases of enlarging head were evaluated on ultrasound to find out the cause. Nine out of 30 patients had multiple cystic lesions in both cerebral hemispheres with or without ventriculomegaly. Three patients showed debris in the cysts suggesting pus, which was confirmed on ultrasoun...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02395750
更新日期:1988-01-01 00:00:00
abstract::Hypertension due to transplant renal artery stenosis was treated with percutaneous transluminal angioplasty (PTA) in 6 children. 8 angioplasties were performed and the follow-up period varied between 3 and 66 months (average 23 months). The stenoses were located at the site of anastomosis in 4 children and distal to t...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012999
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine normal resistive index (RI) values for term neonates during the first day of life as part of an ongoing prospective study of RI values in term infants with perinatal asphyxia. MATERIALS AND METHODS:Forty normal term neonates underwent cranial sonography and Doppler du...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000286
更新日期:2000-09-01 00:00:00
abstract::Magnetic resonance (MR) images of 12 pathologically proven lesions of Langerhans cell histiocytosis (LCH) of bone were reviewed retrospectively. MR identified all lesions, three of which were not identified on plain radiographs. In all cases, MR showed greater abnormality than did plain radiographs. With one exception...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02017655
更新日期:1994-01-01 00:00:00
abstract::Lipoprotein lipase deficiency (LLD) is a rare metabolic disorder that typically presents with skin xanthomas and pancreatitis in childhood. We report a case of LLD in an infant who presented with jaundice caused by a pancreatic head mass. Abdominal imaging also incidentally revealed hyperechoic renal masses caused by ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1560-7
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Presently, the only sonographic parameters used to follow puberty in girls are size and morphology of the uterus and ovaries. Doppler of the uterine artery appears a useful complementary parameter to follow puberty. OBJECTIVE:To determine the potential contribution of Doppler evaluation of the uterine arter...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470100463
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Demand for pediatric cardiac computed tomography (CT) angiography is increasing due to recent advances that reduce the need for sedation and radiation exposure while enhancing diagnostic accuracy. This has resulted in the increasing use of cardiac CT angiography emergently during weekends and after hours. Th...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-020-04659-4
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To offer a descriptive review which characterizes and evaluates the significance of local physeal widening, (cartilaginous signal extending from the physis into the adjacent metaphysis), identified on magnetic resonance (MR) imaging. MATERIALS AND METHODS:MR images (recollected from exams performed between 1...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050206
更新日期:1997-08-01 00:00:00
abstract::We present a case of lethal hypoplastic left heart syndrome missed at routine 20-week antenatal ultrasound examination because the left ventricle was of normal size on the standard four-chamber cardiac view. Hypoplastic left heart syndrome includes a spectrum of cardiac malformations. This case illustrates the difficu...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02026682
更新日期:1991-01-01 00:00:00
abstract::The practice of contrast-enhanced ultrasound in children is in the setting of off-label use or research. The widespread practice of pediatric contrast-enhanced US is primarily in Europe. There is ongoing effort by the Society for Pediatric Radiology (SPR) and International Contrast Ultrasound Society (ICUS) to push fo...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-013-2746-6
更新日期:2013-09-01 00:00:00
abstract::We report an unusual case of a child with a congenital solitary functional kidney complicated by a sports-related posttraumatic Page kidney. The child developed severe hypertension and renal insufficiency requiring percutaneous intervention to preserve renal function. The literature is sparse with no definitive guidel...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1630-x
更新日期:2010-11-01 00:00:00
abstract::Hardcastle syndrome is a rare, autosomally dominant inherited skeletal dysplasia, characterized by diaphyseal sclerosis, medullary stenosis, pathological fractures, bony infarction, and malignant transformation. A 19-year-old proband is presented and discussed, adding a fourth family to the world literature. Radiograp...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01356833
更新日期:1996-09-01 00:00:00
abstract::Narrow duplicated internal auditory canal (IAC) is a rare malformation of the temporal bone that is associated with ipsilateral congenital sensorineural hearing loss. This may be an isolated finding or a part of a syndrome. Radiological examination should demonstrate aplasia or hypoplasia of the neural components of t...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-005-1547-y
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Children are better served by radiologists and technical personnel trained in the care of pediatric patients. However, a variety of obstacles may limit the access of children to dedicated pediatric imaging facilities. OBJECTIVE:We designed and implemented two models for providing community-based imaging by ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050003
更新日期:2000-01-01 00:00:00
abstract::The anatomical anomalies that characterize septo-optic-dysplasia (deMorsier Syndrome) are variable and often subtle. We report imaging studies of nine patients with septo-optic-dysplasia which provide radiologic and ultrasonographic clues to this disorder. In addition, we propose that cerebral schizencephaly may be a ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388642
更新日期:1989-01-01 00:00:00
abstract::Aplasia, hypoplasia and stenosis of the pulmonary artery showed, on scintigraphic investigation, unilateral, homogenous decreased in lung perfusion. In 3 of 4 children with pulmonary sequestration there was a difference in blood flow between the two lungs, or in one part of the lung. Isolated anomalous drainage of pul...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00978815
更新日期:1975-11-24 00:00:00
abstract::As the need for accurate diagnostic imaging often continues throughout a cancer survivor's life, imaging methods with the least toxicity must be used so as to provide needed information without contributing to long-term sequelae that might compound toxicities inherent with the primary disease and its treatment. In thi...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-011-2108-1
更新日期:2011-09-01 00:00:00