High-attenuation mucus plugs on MDCT in a child with cystic fibrosis: potential cause and differential diagnosis.

Abstract:

:High-attenuation mucus plugging is a rare finding in both adults and children. When it occurs, the field of differential diagnoses is typically quite small and includes acute hemorrhage, aspiration of radiodense material, and allergic bronchopulmonary aspergillosis (ABPA). The last of these three diagnoses is the most difficult to make, although ABPA is more commonly seen in children with cystic fibrosis (CF) or asthma. ABPA is radiographically characterized by recurrent mucus plugging, atelectasis, and central bronchiectasis. Thus far, high-attenuation mucus plugs have only been reported in adults. We report a rare case of a child with CF who had high-attenuation mucus plugs and atelectasis that raised the possibility of ABPA. We discuss the differential diagnoses of this finding and the role of multidetector CT in these children.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Morozov A,Applegate KE,Brown S,Howenstine M

doi

10.1007/s00247-007-0471-8

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

592-5

issue

6

eissn

0301-0449

issn

1432-1998

journal_volume

37

pub_type

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