Abstract：
:Land plants are anchored in one place for most of their life cycle and therefore must constantly adapt their growth and metabolism to abiotic stresses such as light intensity, temperature and the availability of water and essential minerals. Thus, plants' subsistence depends on their ability to regulate rapidly gene expression in order to adapt their physiology to their environment. Recent studies indicate that post-transcriptional regulations of gene expression play an important role in how plants respond to abiotic stresses. We will review the different mechanisms of post-transcriptional regulation of nuclear genes expression including messenger RNA (mRNA) processing, stability, localization and protein translation, and discuss their relative importance for plant adaptation to abiotic stress.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Floris M,Mahgoub H,Lanet E,Robaglia C,Menand Bdoi
10.3390/ijms10073168subject
Has Abstractpub_date
2009-07-10 00:00:00pages
3168-85issue
7issn
1422-0067journal_volume
10pub_type
杂志文章,评审abstract：:In plants, microRNAs have been indicated to control various developmental processes, including somatic embryogenesis (SE), which is triggered in the in vitro cultured somatic cells of plants. Although a transcriptomic analysis has indicated that numerous MIRNAs are differentially expressed in the SE of different plant...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20205221
更新日期：2019-10-21 00:00:00
abstract：:Ipomoea pes-caprae is a seashore halophytic plant and is therefore a good model for studying the molecular mechanisms underlying salt and stress tolerance in plant research. Here, we performed Full-length cDNA Over-eXpressor (FOX) gene hunting with a functional screening of a cDNA library using a salt-sensitive yeast ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19113446
更新日期：2018-11-02 00:00:00
abstract：:Neurodegenerative diseases may have distinct genetic etiologies and pathological manifestations, yet share common cellular mechanisms underpinning neuronal damage and dysfunction. These cellular mechanisms include excitotoxicity, calcium dysregulation, oxidative damage, ER stress and neuroinflammation. Recent data hav...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms17081332
更新日期：2016-08-12 00:00:00
abstract：:Human chorionic gonadotropin (hCG) is no longer a single, omnipotent ovulation triggering option. Gonadotropin releasing hormone (GnRH) agonist, initially presented as a substitute for hCG, has led to a new era of administering GnRH agonist followed by hCG triggering. According to this new concept, GnRH agonist enable...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms18051075
更新日期：2017-05-17 00:00:00
abstract：:B cells, plasma cells and antibodies may play a key role in the pathogenesis of multiple sclerosis (MS). This notion is supported by various immunological changes observed in MS patients, such as activation and pro-inflammatory differentiation of peripheral blood B cells, the persistence of clonally expanded plasma ce...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms18102048
更新日期：2017-09-23 00:00:00
abstract：:It is well known that cobalt chloride (CoCl2) can enhance the stability of hypoxia-inducible factor (HIF)-1α. The aim of this study is to detect the effect of CoCl2 on the hypoxia tolerance of mice which were repeatedly exposed to autoprogressive hypoxia. Balb/c mice were randomly divided into groups of chemical pretr...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms150610999
更新日期：2014-06-18 00:00:00
abstract：:The impact of polyunsaturated fatty acid (PUFA) supplementation on phospholipase D (PLD) trafficking and activity in mast cells was investigated. The enrichment of mast cells with different PUFA including α-linolenic acid (LNA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), linoleic acid (LA) or arachidonic...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms14059005
更新日期：2013-04-25 00:00:00
abstract：:The incidence of inflammatory bowel disease (IBD) has increased considerably over the past few decades. In the present review, we discuss several disadvantages existing in the treatment of IBD and current understandings of the structures, sources, and natures of various kinds of non-starch polysaccharides (NSPs). Avai...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms18071372
更新日期：2017-06-27 00:00:00
abstract：:Oxidative stress plays a key role for the development of cardiovascular, metabolic, and neurodegenerative disease. This concept has been proven by using the approach of genetic deletion of reactive oxygen and nitrogen species (RONS) producing, pro-oxidant enzymes as well as by the overexpression of RONS detoxifying, a...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21103405
更新日期：2020-05-12 00:00:00
abstract：:Lichens, composite organisms resulting from the symbiotic association between the fungi and algae, produce a variety of secondary metabolites that exhibit pharmacological activities. This study aimed to investigate the anti-inflammatory activities of the secondary metabolite atraric acid produced by Heterodermia hypol...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21197070
更新日期：2020-09-25 00:00:00
abstract：:The involvement of microRNAs in the control of repressors of human γ-globin gene transcription has been firmly demonstrated, as described for the miR-486-3p mediated down-regulation of BCL11A. On the other hand, we have reported that miR-210 is involved in erythroid differentiation and, possibly, in γ-globin gene up-r...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms18122530
更新日期：2017-11-26 00:00:00
abstract：:Antimicrobial peptides (AMPs) are promising therapeutic agents for treating antibiotic-resistant bacterial infections. Previous studies showed that magainin 2 (isolated from African clawed fogs Xenopus laevis) has antimicrobial activity against gram-positive and gram-negative bacteria. The present study was conducted ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19103041
更新日期：2018-10-05 00:00:00
abstract：:Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are believed to be important for cardiovascular health. Many investigations have been carried out in an attempt to examine the effect of n-3 PUFAs intake, in the form of supplementation or fortified foods, for the management of cardiovascular disease (CVD) and risk facto...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms18071552
更新日期：2017-07-18 00:00:00
abstract：:The anti-stress potential of dietary L-arginine (Arg) was assessed in psychosocially stress-loaded senescence-accelerated (SAMP10) mice. Although this strain of mouse is sensitive to stress, daily administration of Arg at 3 mg/kg significantly suppressed aging-related cognitive decline and behavioral depression at nin...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms22020508
更新日期：2021-01-06 00:00:00
abstract：:The insulin signaling (IIS) pathway plays an important role in the metabolism, growth, development, reproduction, and longevity of an organism. As a key member of the IIS pathway, insulin-like growth factor binding proteins (IGFBPs) are widely distributed a family in invertebrates and vertebrates that are critical in ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms22031056
更新日期：2021-01-21 00:00:00
abstract：:The presented studies focused on the specificity binding of particular casein fractions: αS1-, β- and κ-casein (αS1CN, βCN, κCN), with zinc ions. The binding mechanism was determined by kinetic modeling using results of batch sorption. For this goal, models of zero-order kinetics, pseudo-first-order, pseudo-second-ord...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21218096
更新日期：2020-10-30 00:00:00
abstract：:Our laboratory and others previously showed that Annexin A2 knockout (A2KO) mice had impaired blood-brain barrier (BBB) development and elevated pro-inflammatory response in macrophages, implying that Annexin A2 (AnxA2) might be one of the key endogenous factors for maintaining homeostasis of the neurovascular unit in...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20246125
更新日期：2019-12-05 00:00:00
abstract：:Protein-protein interactions are important for the molecular understanding of the biological processes of proteins. The dimerization of bZIPs (basic leucine zipper proteins) is involved in modifying binding site specificities, altering dimer stability, and permitting a new set of specific protein-to-protein interactio...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms150610005
更新日期：2014-06-04 00:00:00
abstract：:Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, has been shown to inhibit cerebral ischemic injury. However, its potential molecular action on blood-brain barrier (BBB) dysfunction after stroke remains unclear. This study aimed to investigate the effects of ruscogenin on BBB dysfunction a...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms17091418
更新日期：2016-08-29 00:00:00
abstract：:Wounding is a serious environmental stress in plants. Oxylipins such as jasmonic acid play an important role in defense against wounding. Mechanisms to adapt to wounding have been investigated in vascular plants; however, those mechanisms in nonvascular plants remain elusive. To examine the response to wounding in Phy...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21041417
更新日期：2020-02-19 00:00:00
abstract：:Argininosuccinate synthetase (ASS), a key enzyme to synthesize arginine is down regulated in many tumors including hepatocellular carcinoma (HCC). Similar to previous reports, we have found the decrease in ASS expression in poorly differentiated HCC. These ASS(-) tumors are auxotrophic for arginine. Pegylated arginine...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms18061175
更新日期：2017-06-01 00:00:00
abstract：:The role of platelet-rich plasma (PRP) in promoting the healing of bone fractures has not yet been clearly stated. The aim of this prospective clinical study was to evaluate the effectiveness of plasma rich in growth factors (PRGF, a PRP derivate) in the treatment of naturally-occurring bone fractures in dogs. With th...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20051075
更新日期：2019-03-01 00:00:00
abstract：:Molecular determinants of the binding of various endogenous modulators to transient receptor potential (TRP) channels are crucial for the understanding of necessary cellular pathways, as well as new paths for rational drug designs. The aim of this study was to characterise interactions between the TRP cation channel s...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21124323
更新日期：2020-06-17 00:00:00
abstract：:The aim of this study was to select effective and safe microbiocides for the disinfection and protection of historical wooden surfaces at the former Auschwitz II-Birkenau concentration and extermination camp. We tested seven active compounds against bacteria and moulds, of which didecyldimethylammonium chloride and N-...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms17081364
更新日期：2016-08-22 00:00:00
abstract：:Diabetic retinopathy is a common complication of diabetes and remains the leading cause of blindness among the working-age population. For decades, diabetic retinopathy was considered only a microvascular complication, but the retinal microvasculature is intimately associated with and governed by neurons and glia, whi...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms19040942
更新日期：2018-03-22 00:00:00
abstract：:Melanocytes in the skin play an indispensable role in the pigmentation of skin and its appendages. It is well known that the embryonic origin of melanocytes is neural crest cells. In adult skin, functional melanocytes are continuously repopulated by the differentiation of melanocyte stem cells (McSCs) residing in the ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms161226207
更新日期：2015-12-21 00:00:00
abstract：:Tetraploid black locust (Robinia pseudoacacia L.) is adaptable to salt stress. Here, we compared morphological, physiological, ultrastructural, and proteomic traits of leaves in tetraploid black locust and its diploid relatives under salt stress. The results showed that diploid (2×) plants suffered from greater negati...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms141020299
更新日期：2013-10-14 00:00:00
abstract：:Advances in the use of targeted and immune therapies have revolutionized the clinical management of melanoma patients, prolonging significantly their overall and progression-free survival. However, both targeted and immune therapies suffer limitations due to genetic mutations and epigenetic modifications, which determ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21124544
更新日期：2020-06-26 00:00:00
abstract：:Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted increasing attention in many biomedical fields. In magnetic drug targeting SPIONs are injected into a tumour supplying artery and accumulated inside the tumour with a magnet. The effectiveness of this therapy is thus dependent on magnetic properties, s...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms16059368
更新日期：2015-04-24 00:00:00
abstract：:Cultured human primary cells have a limited lifespan undergoing dedifferentiation or senescence. Anterior cruciate ligaments (ACL) are hypocellular but tissue engineering (TE) requires high cell numbers. Simian virus (SV) 40 tumor (T) antigen expression could extend the lifespan of cells. This study aimed to identify ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21020593
更新日期：2020-01-16 00:00:00
