Cardiac angiosarcoma with cardiac tamponade diagnosed as a ruptured aneurysm of the sinus valsalva.

abstract：OBJECTIVE:To describe changes in Japanese clinical trial regulations after the implementation of the Clinical Trials Act in April 2018. METHODS:First, how to apply multiple regulations after the enforcement of Clinical Trials Act was described. Second, the changes in the number of clinical trials in the National Cance...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Shibata T

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:We evaluated the efficacy of our quality assurance (QA) program of radiation therapy (RT) in a prospective phase II study. This is the first description of the experience of the Japan Radiation Oncology Group (JAROG) with this program. METHODS:Clinical records, all diagnostic radiological films or color pho...

journal_title：Japanese journal of clinical oncology

authors： Isobe K,Kagami Y,Higuchi K,Kodaira T,Hasegawa M,Shikama N,Nakazawa M,Fukuda I,Nihei K,Ito K,Teshima T,Oguchi M,Japan Radiation Oncology Group (JAROG).

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:Breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis. The occurrence of micrometastasis has been suggested to relate with prognostic features of breast cancer, such as lymph node metastasis and the presence of vascular invasi...

journal_title：Japanese journal of clinical oncology

authors： Jung YS,Lee KJ,Kim HJ,Yim HE,Park JS,Soh EY,Kim MW,Park HB

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Most cancer patients become increasingly anxious toward the end of their life. The objective of this study was to identify predictors of increased opioid dosage in the last week of a terminal cancer patient's life. METHODS:We retrospectively reviewed charts of patients who died in our palliative care unit. W...

journal_title：Japanese journal of clinical oncology

authors： Miura T,Matsumoto Y,Motonaga S,Hasuo H,Abe K,Kinoshita H

更新日期：2014-11-01 00:00:00

abstract：:Primary tympanic membrane cancer is very rare; metastatic cancer to the tympanic membrane is extremely rare and presents diagnostic challenges. We report a case of metastatic hepatocellular carcinoma in the tympanic membrane. The presenting symptom was hearing loss. Physical examination revealed a friable granulomatou...

journal_title：Japanese journal of clinical oncology

authors： Wu ZS,Li SC,Ho HC,Tseng JE,Lin YH,Su YC

更新日期：2011-02-01 00:00:00

abstract：:A 3-year-old girl with Philadelphia chromosome positive acute lymphoblastic leukemia developed pulmonary aspergillosis during severe neutropenia by re-induction therapy. She was treated by intravenous fluconazole, oral itraconazole with plasma level monitoring and surgical resection of the focus for 3 months after cli...

journal_title：Japanese journal of clinical oncology

authors： Kudoh T,Suzuki N,Hatakeyama N,Mizue N,Hori T,Oda T,Watanabe J,Imamura M,Chiba S

更新日期：2001-06-01 00:00:00

abstract：:Subglottic carcinoma is rare and has a poor prognosis. It is usually treated with surgical resection, external beam irradiation (EBR) and/or a combination of both. Intraluminal irradiation (IR) as a curative treatment for subglottic carcinoma has never been reported. We report a case of subglottic carcinoma in a 66-ye...

journal_title：Japanese journal of clinical oncology

authors： Wakisaka M,Fuwa N,Matsumoto A,Tachibana H,Kodaira T,Furutani K,Kamata M,Mori H

更新日期：2003-02-01 00:00:00

abstract：:Following a simple cholecystectomy, a 63-year-old woman with gallstones was histologically diagnosed as having minute squamous cell carcinoma of the gallbladder. A laparotomy revealed a small, firm nodule that appeared to be an adenoma, which was palpated in the fundus of the gallbladder. The resected gallbladder cont...

journal_title：Japanese journal of clinical oncology

authors： Roppongi T,Takeyoshi I,Ohwada S,Sato Y,Fujii T,Honma M,Morishita Y

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Anatomical segmentectomy has the potential to replace lobectomy as the standard procedure for early stage non-small cell lung cancer. We investigated the safety and feasibility of robotic anatomical segmentectomy for non-small cell lung cancer. METHODS:Overall 20 patients underwent robotic anatomical segment...

journal_title：Japanese journal of clinical oncology

authors： Kagimoto A,Tsutani Y,Izaki Y,Handa Y,Mimae T,Miyata Y,Okada M

更新日期：2020-04-07 00:00:00

abstract：OBJECTIVE:Laminin-332, a marker of epithelial-mesenchymal transition, is composed of a heterotrimer of α3, β3 and γ2 chains that regulates cell adhesion and migration. This study aimed to disclose the respective clinical significance of laminin β3 immunoexpression in colorectal cancer as a prognostic factor and a predi...

journal_title：Japanese journal of clinical oncology

authors： Fukazawa S,Shinto E,Tsuda H,Ueno H,Shikina A,Kajiwara Y,Yamamoto J,Hase K

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Low-dose-rate (LDR) brachytherapy is an effective treatment for tongue cancer. However, little is known about the biological mechanism underlying this therapy, characterized by delivery of continuous exposures of LDR irradiation. It is reported that lower microvessel density (MVD), lower Ki-67 index or higher...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Someya M,Nagakura H,Nakata K,Oouchi A,Takagi M,Hareyama M

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:A patient with multiple myeloma developed myelodysplastic syndrome (MDS). Chromosomal analysis performed after the development of MDS revealed monosomy of chromosome 9 in all the meta-phases. We wished to identify the extent of the clone with the chromosomal abnormality originating from MDS clone. METHODS:A...

journal_title：Japanese journal of clinical oncology

authors： Kobayashi Y,Nakayama M,Uemura N,Takeyama K,Tobinai K,Takenaka T,Choi SH,Satoh H,Mori S,Asano S

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:This study was conducted to evaluate the efficacy and safety of pegylated liposomal doxorubicin (PLD) in Japanese patients with Müllerian carcinoma having a therapeutic history of platinum-based chemotherapy. METHODS:Patients who were diagnosed with Müllerian carcinoma (epithelial ovarian carcinoma, primary ...

journal_title：Japanese journal of clinical oncology

authors： Katsumata N,Fujiwara Y,Kamura T,Nakanishi T,Hatae M,Aoki D,Tanaka K,Tsuda H,Kamiura S,Takehara K,Sugiyama T,Kigawa J,Fujiwara K,Ochiai K,Ishida R,Inagaki M,Noda K

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To clarify the clinical outcomes of stereotactic body radiotherapy for colorectal cancer-derived bone metastases and identify factors predicting treatment failure. METHODS:Patients treated with stereotactic body radiotherapy for bone metastases from colorectal cancer between September 2013 and June 2019 were...

journal_title：Japanese journal of clinical oncology

authors： Ito K,Yamaguchi T,Ogawa H,Nakajima Y,Karasawa K

更新日期：2020-12-16 00:00:00

abstract：:The prognosis of pancreatic adenocarcinoma is dismal. Hence, advances in multidisciplinary treatment strategies, including surgery, are urgently needed. Early recurrence of distant organ metastases suggests that there are occult metastases even in cases with resectable disease. Several randomized controlled trials on ...

journal_title：Japanese journal of clinical oncology

authors： Motoi F,Unno M

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:The disease status of axillary lymph nodes at diagnosis is the most powerful predictor of prognosis for patients with breast cancer. Axillary lymph node dissection (ALND) has been the standard treatment. Recently, lymphatic mapping and sentinel lymph node biopsy (SNB) have been suggested as alternatives to A...

journal_title：Japanese journal of clinical oncology

authors： Koizumi M,Makita M,Yoshimoto M,Kasumi F,Sakamoto G,Ogata E

更新日期：2002-12-01 00:00:00

abstract：:K-ras mutation is the most common oncogenic alteration in various human cancers including colorectal carcinomas. Point mutations have the potential to activate the K-ras gene if they occur in the critical coding sequences. Almost all of these mutations have been localized in codons 12, 13 and 61. We report a case of c...

journal_title：Japanese journal of clinical oncology

authors： Miyakura Y,Sugano K,Fukayama N,Konishi F,Nagai H

更新日期：2002-06-01 00:00:00

abstract：Background:Shorter duration of infusion of monoclonal antibody treatments may reduce treatment burden and improve healthcare resource utilization. Methods:This phase II study recruited Japanese patients with previously untreated CD20+ B-cell non-Hodgkin lymphoma. Patients received intravenous obinutuzumab 1000 mg by r...

journal_title：Japanese journal of clinical oncology

authors： Ohmachi K,Ando K,Kinoshita T,Kumagai K,Hatake K,Ishikawa T,Teshima T,Kato K,Izutsu K,Ueda E,Nakai K,Kuriki H,Tobinai K

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to evaluate the liver metastasis risk among colorectal cancer patients with liver cirrhosis. METHODS:This was a nationwide population-based cohort study of 2973 newly diagnosed colorectal cancer patients with liver cirrhosis and 11 892 age-sex matched controls enrolled in Taiwan betw...

journal_title：Japanese journal of clinical oncology

authors： Chiou WY,Chang CM,Tseng KC,Hung SK,Lin HY,Chen YC,Su YC,Tseng CW,Tsai SJ,Lee MS,Li CY

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:In 2009, the TNM classification of malignant tumors was revised, and the renewal of the T2-4 stage in renal cell carcinoma was adopted. To date, however, the staging of ipsilateral solitary adrenal involvement in renal cell carcinoma has not been sufficiently evaluated. METHODS:We retrospectively reviewed th...

journal_title：Japanese journal of clinical oncology

authors： Takayama T,Sugiyama T,Kai F,Ito T,Furuse H,Mugiya S,Ozono S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:We investigated the expression of PyNPase both in cancer cells and in stroma cells to clarify the correlation between PyNPase expression and the prognosis of patients with colorectal cancer. METHODS:Using immunohistochemical staining with an anti-PyNPase antibody, the PyNPase expression in tissues from 114 ...

journal_title：Japanese journal of clinical oncology

authors： Osanai T,Ichikawa W,Takagi Y,Uetake H,Nihei Z,Sugihara K

更新日期：2001-10-01 00:00:00

abstract：:In Japan, lateral lymph node dissection (LLND) is generally performed for the treatment of T3-4 lower rectal carcinoma, and not for T1 lower rectal carcinoma, because of a low positive rate in patients with T1 lesion. We experienced a rare case of lateral pelvic lymph node recurrence after total mesorectal resection f...

journal_title：Japanese journal of clinical oncology

authors： Hara J,Yamamoto S,Fujita S,Akasu T,Moriya Y

更新日期：2008-04-01 00:00:00

abstract：:Sarcoma of the hypopharynx has been reported very rarely in the literature, only six cases having been found among all head and neck malignancies reported to SEER (Surveillance, Epidemiology, and End Results) during 1973-1987. We report a 14-year-old boy with a huge malignant soft tissue sarcoma arising from the hypop...

journal_title：Japanese journal of clinical oncology

authors： Lin JC,Hsu CY,Kwan PC,Shen WC,Jan JS,Ho WL

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:A retrospective analysis was made to clarify the relationship between prognosis, radiation dose and survival of brain stem gliomas. METHODS:From 1983 to 1995, 22 children with brain stem tumors were treated by radiotherapy in the Veterans General Hospital-Taipei. Twelve patients had pathology proof and the ...

journal_title：Japanese journal of clinical oncology

authors： Liu YM,Shiau CY,Wong TT,Wang LW,Wu LJ,Chi KH,Chen KY,Yen SH

更新日期：1998-08-01 00:00:00

abstract：:Carcinoid tumors located in the minor duodenal papilla are extremely rare, with only a few cases reported in the literature. Herein, we report the case of a 71-year-old man with a 12-mm carcinoid tumor at the minor duodenal papilla with lymph node metastases. Multidetector-row computed tomography with contrast enhance...

journal_title：Japanese journal of clinical oncology

authors： Fukami Y,Kurumiya Y,Mizuno K,Sekoguchi E,Kobayashi S,Ito A,Tomida A,Onishi S,Shirotsuki R,Okubo K,Narita M

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:We evaluated the results of imatinib dose escalation in patients with advanced gastrointestinal stromal tumors (GISTs) after disease progression on standard-dose imatinib. METHODS:Clinical data from patients with metastatic or unresectable GISTs whose dose of imatinib was increased after disease progression ...

journal_title：Japanese journal of clinical oncology

authors： Park I,Ryu MH,Sym SJ,Lee SS,Jang G,Kim TW,Chang HM,Lee JL,Lee H,Kang YK

更新日期：2009-02-01 00:00:00

abstract：:A rare case of adult T-cell leukemia/lymphoma with a giant exophytic gastric tumor invading the anterior abdominal wall is presented. The patient was a 52-year-old woman, who had a history of strongyloidiasis. Although the patient was serologically positive for HTLV-I antibody, there were no lymphoma cells in the peri...

journal_title：Japanese journal of clinical oncology

authors： Hiroyasu S,Shiraishi M,Shimabukuro M,Kusano T,Muto Y

更新日期：1996-10-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：:Endometrial stromal sarcoma is known to be a hormone-dependent tumor. Efficacy of hormonal therapy including high-dose progestins, aromatase inhibitors or gonadotropin-releasing hormone analogs has been reported. We report a case of recurrent endometrial stromal sarcoma, the tumor cells of which were strongly positive...

journal_title：Japanese journal of clinical oncology

authors： Akashi D,Todo Y,Shimada C,Okamoto K,Minobe S,Kato H

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS:We retrospectively reviewed a database of patients with retinoblastoma and osteosarc...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara T,Fujiwara M,Numoto K,Ogura K,Yoshida A,Yonemoto T,Suzuki S,Kawai A

更新日期：2015-12-01 00:00:00