Abstract:
:Subglottic carcinoma is rare and has a poor prognosis. It is usually treated with surgical resection, external beam irradiation (EBR) and/or a combination of both. Intraluminal irradiation (IR) as a curative treatment for subglottic carcinoma has never been reported. We report a case of subglottic carcinoma in a 66-year-old man, who was effectively treated with IR combined with EBR. IR was conducted using low dose rate iridium-192 thin wires at a subglottic mucosal dose of 5.1-6.0 Gy per fraction, with a total dose of 43.8 Gy in eight fractions. EBR was administered, using cobalt-60 and 6 MV X-rays delivered at 2 Gy per fraction, with a total dose of 66 Gy in 33 fractions. Complete response was obtained without serious complications and no recurrence occurred in the 79-month follow-up period. IR combined with EBR is useful as a potential curative treatment. It should be considered as one of the treatment options for subglottic carcinoma.
journal_name
Jpn J Clin Oncoljournal_title
Japanese journal of clinical oncologyauthors
Wakisaka M,Fuwa N,Matsumoto A,Tachibana H,Kodaira T,Furutani K,Kamata M,Mori Hdoi
10.1093/jjco/hyg016keywords:
subject
Has Abstractpub_date
2003-02-01 00:00:00pages
89-92issue
2eissn
0368-2811issn
1465-3621journal_volume
33pub_type
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