Unclear loss of consciousness after clobutinol intake.

Abstract:

:The case of a 13-month-old boy with a diagnosis of unclear unconsciousness is reported on. As the physical examination did not lead to any explanation of his condition, the administration of drugs in the context of Munchausen syndrome by proxy was suspected. Complex forensic-toxicological analyses using HPLC/UV, LC/MS/MS, and GC/MS identified ambroxol and clobutinol, two drugs that are indicated for acute respiratory diseases. No other central active compounds were detected. The accusation of intentional bodily injury raised against the parents could be rebutted, since the boy's unconsciousness could be explained with a rare but harmful side effect of the antitussive clobutinol.

journal_name

Forensic Sci Int

authors

Kirschbaum KM,Musshoff F,Madea B

doi

10.1016/j.forsciint.2009.04.021

subject

Has Abstract

pub_date

2009-08-10 00:00:00

pages

e37-40

issue

1-3

eissn

0379-0738

issn

1872-6283

pii

S0379-0738(09)00199-6

journal_volume

189

pub_type

杂志文章
  • Destruction of intracerebrally applied red blood cells in cervical lymph nodes. Experimental investigations.

    abstract::In rabbits, intracerebrally applied erythrocytes can move with the cerebrospinal fluid along connecting pathways between the subarachnoid space and the cervical lymph nodes. This study compares the time dependency for the degradation of intracerebrally injected erythrocytes in the brain as well as in the cervical lymp...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(83)90089-0

    authors: Oehmichen M,Wiethölter H,Grüninger H,Gencic M

    更新日期:1983-01-01 00:00:00

  • Novel age estimation model based on development of permanent teeth compared with classical approach and other modern data mining methods.

    abstract::In order to analyze and improve the dental age estimation in children and adolescents for forensic purposes, 22 age estimation methods were compared to a sample of 976 orthopantomographs (662 males, 314 females) of healthy Czech children and adolescents aged between 2.7 and 20.5 years. All methods are compared in term...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2017.08.005

    authors: Štepanovský M,Ibrová A,Buk Z,Velemínská J

    更新日期:2017-10-01 00:00:00

  • Chemical fingerprinting of unevaporated automotive gasoline samples.

    abstract::The comparison of two or more samples of liquid gasoline (petrol) to establish a common origin is a difficult problem in the forensic investigation of arsons and suspicious fires. A total of 35 randomly collected samples of unevaporated gasoline, covering three different grades (regular unleaded, premium unleaded and ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(03)00081-1

    authors: Sandercock PM,Du Pasquier E

    更新日期:2003-06-24 00:00:00

  • Handwriting based writer recognition using implicit shape codebook.

    abstract::Writer characterization from images of handwriting has remained an important research problem in the handwriting recognition community that finds applications in forensics, paleography and neuropsychology. This paper presents a study to evaluate the effectiveness of an implicit shape codebook technique to recognize wr...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2019.05.014

    authors: Bennour A,Djeddi C,Gattal A,Siddiqi I,Mekhaznia T

    更新日期:2019-08-01 00:00:00

  • Distinguishing antemortem from postmortem injuries by LTB4 quantification.

    abstract::Leukotriene B4 (LTB4) in skin samples from seven forensic cases was detected by HPLC to distinguish their antemortem or postmortem origin. In total, there were thirteen antemortem and seven postmortem specimens. The results showed that LTB4 was found in all antemortem wound specimens which were either fresh, or refrig...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(96)01938-x

    authors: He L,Zhu J

    更新日期:1996-07-31 00:00:00

  • The color(s) of human hair--forensic hair analysis with SpectraCube.

    abstract::Human hair is among the most common kind of evidence secured at crime scenes. Although DNA analysis through STR-typing is possible in principle, it is not very promising for telogenic hair or single hairs. For the mixed traces frequently found in practice, composed of different hair from an unknown number of individua...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2008.12.018

    authors: Birngruber C,Ramsthaler F,Verhoff MA

    更新日期:2009-03-10 00:00:00

  • Experimental study of Lucilia sericata (Diptera Calliphoridae) larval development on rat cadavers: Effects of climate and chemical contamination.

    abstract::Household products such as bleach, gasoline or hydrochloric acid have been used to mask the presence of a cadaver or to prevent the colonization of insects. These types of chemicals affect insect development and alter the forensic entomology analysis. This study was designed to test the effects of six household produc...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.05.032

    authors: Aubernon C,Charabidzé D,Devigne C,Delannoy Y,Gosset D

    更新日期:2015-08-01 00:00:00

  • Evaluation of non-metric variation in the crania of black and white perinates.

    abstract::Reports in the literature suggest that diagnostic differences in craniofacial morphology between blacks and whites arise very early in development. These reports, however, have not been consistent regarding which traits are diagnostic and have failed to provide forensic anthropologists with a reliable method of assess...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2005.02.009

    authors: Weinberg SM,Putz DA,Mooney MP,Siegel MI

    更新日期:2005-07-16 00:00:00

  • Post-mortem evaluation of drowning with whole body CT.

    abstract:PURPOSE:The aim of this study is to investigate the value of whole body computed tomography (WB-CT) in bodies recovered from water by analysis of the imaging findings after drowning. METHODS:The bodies of 41 drowning victims and 9 persons who died from mechanical asphyxia by hanging underwent post-mortem whole body co...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.01.008

    authors: Vander Plaetsen S,De Letter E,Piette M,Van Parys G,Casselman JW,Verstraete K

    更新日期:2015-04-01 00:00:00

  • Evaluating the evidentiary value of the analysis of skeletal trauma in forensic research: A review of research and practice.

    abstract::Understanding bone trauma characteristics is a fundamental component of forensic investigations that can assist in understanding the nature of blunt trauma related deaths. The variation of each blunt force trauma (BFT) injury is dependent on a magnitude of factors including, age, sex, health, angle of impact, impact m...

    journal_title:Forensic science international

    pub_type: 杂志文章,评审

    doi:10.1016/j.forsciint.2020.110140

    authors: Dempsey N,Blau S

    更新日期:2020-02-01 00:00:00

  • Isolation of the DNA minisatellite probe MZ 1.3 and its application to DNA 'fingerprinting' analysis.

    abstract::A minisatellite probe, MZ 1.3, detecting hypervariable fragment patterns was isolated from a human genomic library. A repetitive sequence of 27 bp length was identified which is contained in the probe approx. 40 times. The MZ 1.3 repeat shows variable homology of 53-73% to the repetitive sequence of the protein III ge...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(90)90252-t

    authors: Schacker U,Schneider PM,Holtkamp B,Bohnke E,Fimmers R,Sonneborn HH,Rittner C

    更新日期:1990-02-01 00:00:00

  • Suicide of a cyclist.

    abstract::The rate of suicides in road traffic fatalities is estimated at 1-8% depending on the investigated study material. Especially single-car accidents, for which no technical reason or driving error is apparent, are considered suspicious. The elucidation of suicides in road traffic is difficult if there are no relevant cl...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2010.11.023

    authors: Schmidt U,Rost T,Jungmann L,Pollak S

    更新日期:2011-04-15 00:00:00

  • Discrimination of cultivated silk and wild silk by conventional instrumental analyses.

    abstract::In Japan, recent trends have seen wild silk preferred over cultivated silk because of its texture. Some cases of fraud have occurred where cultivated silk garments are sold as wild silk. Samples from these cases, morphological observation using light microscope and polarized microscope have been conducted in forensic ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2013.05.004

    authors: Matsuyama Y,Nagatani Y,Goto T,Suzuki S

    更新日期:2013-09-10 00:00:00

  • Obtaining absorption spectra from single textile fibers using a liquid crystal tunable filter microspectrophotometer.

    abstract::Visible absorption spectra were recorded for single textile fibers using a microspectrophotometer based on a liquid crystal tunable filter. Spectra compared well with results from a conventional instrument. Some advantages include very fast and simple sample preparation and easy comparison of multiple fibers at the sa...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2011.01.014

    authors: Markstrom LJ,Mabbott GA

    更新日期:2011-06-15 00:00:00

  • Errors in the determination of the point of origin of bloodstains.

    abstract::Bloodstain pattern analysts are sometimes called upon to determine the point of origin of a pattern of bloodstains. A derivation of expressions for the uncertainties deltaX and deltaY in the coordinates of the point of origin P(X, Y) of two bloodstains on a surface has recently been published. These uncertainties were...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2005.10.023

    authors: Rowe WF

    更新日期:2006-08-10 00:00:00

  • Toxicological screen on gastric aspirates: the Singapore experience.

    abstract::In the early eighties, in response to increasing self-poisoning incidents by pharmaceuticals in Singapore, a comprehensive wide-sweep screen for these drugs in clinical gastric aspirates was devised and implemented by us. The toxicological screen which involved quadruplicate extractions, two in acidic conditions and t...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(92)90158-s

    authors: Chao TC,Lo DS,Gunasegaram R,Tan-Siew WF,Tay MM

    更新日期:1992-05-01 00:00:00

  • Utilizing AFIS searching tools to reduce errors in fingerprint casework.

    abstract::Fifty-six (56) adjudicated, property crime cases involving fingerprint evidence were reviewed using a case-specific AFIS database tool. This tool allowed fingerprint experts to search latent prints in the cases against a database of friction ridge exemplars limited to only the individuals specific to that particular c...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.07.054

    authors: Langenburg G,Hall C,Rosemarie Q

    更新日期:2015-12-01 00:00:00

  • Forensic significance of postmortem estimation of the blood cerebrospinal fluid barrier permeability.

    abstract::Albumin concentration in cerebrospinal fluid (CSF) and plasma was determined in 44 cadavers divided into three groups on the basis of death agony duration. The same was determined in a control group of 42 patients with no demonstrable neurological disease. Following Schuller's method, the evaluation of the blood CSF b...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(83)90007-5

    authors: Mangin P,Lugnier AA,Chaumont AJ,Offner M,Grucker M

    更新日期:1983-08-01 00:00:00

  • Metric characterization of the human coxal bone on a recent Italian sample and multivariate discriminant analysis to determine sex.

    abstract::The ability of human pelvic bones to sexually differentiate has been of great interest in forensic anthropology for quite some time as it allows for the determination of skeletal sex by combining metric and morphological data. However, the criteria for determining the sex of a skeleton must be calibrated according to ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2012.06.014

    authors: Vacca E,Di Vella G

    更新日期:2012-10-10 00:00:00

  • Injuries to the hyoid bone and laryngeal cartilages: effectiveness of different methods of medico-legal investigation.

    abstract::The article is devoted to the comparative analysis of effectiveness of the most widely used methods for medico-legal examination of the hyoid bone and laryngeal cartilages, i.e. palpation, radiography and complete preparation. A consecutive study of 137 cases of hanging (including 20 cases of roentgenological analysis...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(97)00101-1

    authors: Khokhlov VD

    更新日期:1997-08-22 00:00:00

  • Comparison of practical techniques to develop latent fingermarks on fired and unfired cartridge cases.

    abstract::We have tested some widely used and practical fingermark enhancement techniques such as powdering (regular powder dusting and magnetic powder application), cyanoacrylate fuming, fluorescent dying (basic yellow 40), gun blueing solutions and acidified hydrogen peroxide solutions. The results were evaluated and compared...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.02.012

    authors: Girelli CM,Lobo BJ,Cunha AG,Freitas JC,Emmerich FG

    更新日期:2015-05-01 00:00:00

  • The experimental and numerical study of indirect effect of a rifle bullet on the bone.

    abstract::We study the transient indirect effect of a rifle bullet on bone in the gelatin-bone composite target experimentally and computationally. The process of a 56 type 7.62-mm rifle bullet penetrating the composite target has been simulated using numerical method. The experiment provided the criteria for verifying the corr...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.10.032

    authors: Zhang X,Xu C,Wen Y,Luo S

    更新日期:2015-12-01 00:00:00

  • Chemical profiling of the street cocktail drug 'nyaope' in South Africa using GC-MS II: Stability studies of the cannabinoid, opiate and antiretroviral components during sample storage.

    abstract::Nyaope is a mixture of low grade heroin, cannabis products, antiretroviral drugs and other materials added as bulking agents. It is a highly physically additive mixture which is smoked by users. As part of the development of a method for the analysis and profiling of nyaope this study evaluates the stability of the ca...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2019.04.040

    authors: Mthembi PM,Mwenesongole EM,Cole MD

    更新日期:2019-07-01 00:00:00

  • Bone histomorphometry of the clavicle in a forensic sample from Albania.

    abstract::Forensic assessment of skeletal material includes age estimation of unknown individuals. When dealing with extremely fragmented human remains that lack macro-features used in age estimation, histological assessment of the skeletal elements can be employed. Historically, microscopic methods for age assessment used by f...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2020.110335

    authors: Kranioti EF,Michopoulou E,Tsiminikaki K,Bonicelli A,Kalochristianakis M,Xhemali B,Paine RR,García-Donas JG

    更新日期:2020-08-01 00:00:00

  • Results of a collaborative study of the EDNAP group regarding mitochondrial DNA heteroplasmy and segregation in hair shafts.

    abstract::A collaborative exercise was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the distribution of mitochondrial DNA (mtDNA) heteroplasmy amongst the hairs of an individual who displays point heteroplasmy in blood and buccal cells. A second aim of the exercise was to study reproducibility of...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/S0379-0738(03)00181-6

    authors: Tully G,Barritt SM,Bender K,Brignon E,Capelli C,Dimo-Simonin N,Eichmann C,Ernst CM,Lambert C,Lareu MV,Ludes B,Mevag B,Parson W,Pfeiffer H,Salas A,Schneider PM,Staalstrom E

    更新日期:2004-02-10 00:00:00

  • Interlaboratory comparison of quantitative determination of amphetamine and related compounds in hair samples.

    abstract::Testing human hair for drugs of abuse is a relatively new technique which requires control before being fully accepted in justice applications. Laboratories must be able to demonstrate that they can accurately determine what drugs are present in unknown hair samples and at what levels. To date few exercises have been ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(96)02058-0

    authors: Kintz P,Cirimele V

    更新日期:1997-01-17 00:00:00

  • Raman spectroscopy and microspectrophotometry of reactive dyes on cotton fibres: analysis and detection limits.

    abstract::A collaborative study on Raman spectroscopy and microspectrophotometry (MSP) was carried out by members of the ENFSI (European Network of Forensic Science Institutes) European Fibres Group (EFG) on different dyed cotton fabrics. The detection limits of the two methods were tested on two cotton sets with a dye concentr...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2012.05.025

    authors: Massonnet G,Buzzini P,Monard F,Jochem G,Fido L,Bell S,Stauber M,Coyle T,Roux C,Hemmings J,Leijenhorst H,Van Zanten Z,Wiggins K,Smith C,Chabli S,Sauneuf T,Rosengarten A,Meile C,Ketterer S,Blumer A

    更新日期:2012-10-10 00:00:00

  • Simultaneous determination of pethidine (meperidine), phenoperidine, and norpethidine (normeperidine), their common metabolite, by gas chromatography with selective nitrogen detection.

    abstract::This article describes a selective gas chromatographic method for the resolution and quantification of phenoperidine and its two metabolites, pethidine (meperidine) and norpethidine (normeperidine). Drugs and SKF 525 A, the internal standard, are separated from plasma by solvent extraction under alkaline conditions. T...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(89)90154-0

    authors: Kintz P,Godelar B,Mangin P,Lugnier AA,Chaumont AJ

    更新日期:1989-12-01 00:00:00

  • Chemometric approach for discriminating tobacco trademarks by near infrared spectroscopy.

    abstract::Cigarettes are consumer products with a broad market-driven orientation. In order to satisfy the different needs of smokers, cigarette trademarks with different aroma, taste and appearance are available on the market. In this study near infrared (NIR) spectroscopy in combination with chemometrics was applied in order ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2018.10.016

    authors: Omar J,Slowikowski B,Boix A

    更新日期:2019-01-01 00:00:00

  • Third molar root development in relation to chronological age: a large sample sized retrospective study.

    abstract::The aim of the present investigation, which is a continuation and extension of a previous published pilot study [Forensic Sci. Int. 129 (2002) 110], was to calculate the chronological age of an individual based on the dental developmental stages of third molars (so-called wisdom teeth). The evaluated material consiste...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(03)00263-9

    authors: Gunst K,Mesotten K,Carbonez A,Willems G

    更新日期:2003-09-09 00:00:00