Abstract:
PURPOSE:A U-shaped relation between alcohol use and mortality may be due to biological hormesis, differential response (i.e., effect modification) by health status or changes in alcohol use with ill-health and aging (i.e., reverse causality).We examined whether alcohol had the same association with mortality in healthy and unhealthy older people. METHODS:We used Cox regression analysis to examine the association of alcohol with mortality by health status in a population-based cohort of 56,167 people (65+ years), enrolled during July 1998 to December 2000 in Hong Kong. RESULTS:After a mean follow-up of 4.1 years, there were 3,819 deaths in 54,087 subjects. Adjusted for age, socioeconomic position and lifestyle, both occasional and moderate types of alcohol use were associated with lower mortality compared to never-drinkers, relative risk (RR) 0.72 (95% confidence interval [CI] 0.63-0.83) and 0.73 (95% CI 0.59-0.90) in men and 0.77 (95% CI 0.64-0.94) and 0.54 (95% CI 0.29-1.01) in women. However, these associations were not maintained in those with good health status: RR 1.02 (95% CI 0.74-1.39) and 1.09 (95% CI 0.71-1.68) in men and 0.63 (95% CI 0.36-1.12) and 1.27 (95% CI 0.40-4.01) in women. CONCLUSIONS:Moderate alcohol use may only be beneficial for older adults in poor health.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Sun W,Schooling CM,Chan WM,Ho KS,Lam TH,Leung GMdoi
10.1016/j.annepidem.2009.01.011subject
Has Abstractpub_date
2009-06-01 00:00:00pages
396-403issue
6eissn
1047-2797issn
1873-2585pii
S1047-2797(09)00042-8journal_volume
19pub_type
杂志文章abstract:PURPOSE:To examine geographic variation in the incidence of ischemic stroke (IS) and acute myocardial infarction (AMI) in Finland during 1991-2003. METHODS:Data included all cases of first IS (n = 115,383) and AMI (n = 205,213) in persons aged 35-84 years. We used full Bayesian spatial shared component disease models ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2007.10.008
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:Population-based cancer incidence rates of the corpus uteri, cervix uteri, and ovaries are underestimated if they fail to remove women not at risk for developing the cancers from the denominator in the race calculation. This study compares incidence rates among selected racial groups for these cancers before an...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2006.06.001
更新日期:2006-12-01 00:00:00
abstract::The following is based on my remarks on receipt of the 2015 ACE award for outstanding contributions to epidemiology. ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2016.02.005
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:To examine community differences in cardiovascular disease (CVD) risk factors among black and white young adults by combining data from two large epidemiologic studies. METHODS:Data are from participants aged 20-31 years in the Coronary Artery Risk Development In Young Adults (CARDIA) study (1987-1988; N = 412...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(97)00127-0
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:Examine the complex relationships among metabolic syndrome components in black and white individuals by growth periods. METHODS:Path analyses of metabolic syndrome components were performed on 8203 black and white healthy subjects (64.3% white and 47.9% male) comprising children (4-11 years), adolescents (12-1...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2007.07.090
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:C-reactive protein (CRP), Chlamydia pneumonia, Helicobacter pylori, and cytomegalovirus (CMV) have each been associated with atherosclerosis. We assessed how infection and CRP related to risk for subsequent myocardial infarction (MI). METHODS:Using a nested case-control design, we assessed how these factors in...
journal_title:Annals of epidemiology
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abstract:PURPOSE:Socioeconomic status (SES) as a risk factor for mortality in type 1 diabetes (T1D) has not been adequately studied prospectively. METHODS:Complete clinical and SES (income, education, occupation) data were available for 317 T1D participants in the Pittsburgh Epidemiology of Diabetes Complications Study within ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.02.011
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:We sought to determine if the rate of increase in body mass index (BMI) differs between first generation immigrant children (child and both parents born outside Canada); second generation immigrant children (child born in Canada with at least one parent born outside Canada); and native-born children (child a...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.01.002
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:The aim of the study was to assess the relation between family wealth and depression in U.S. adults. METHODS:Participants were 5134 members of the 2015-2016 National Health and Nutrition Examination Survey who were aged 18 years or older and completed the depression screener. Using the Patient Health Questionn...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.02.001
更新日期:2020-03-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.01.006
更新日期:2004-09-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2013.02.002
更新日期:2013-05-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2005.02.001
更新日期:2005-11-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2014.07.006
更新日期:2014-10-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.09.003
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To determine whether 3-hydroxy-3-methylglutaryl coenzyme A inhibitors (statins) are associated with a decreased risk of colorectal cancer. METHODS:The population included 159,219 postmenopausal women enrolled in the Women's Health Initiative in which 2000 pathologically confirmed cases of colorectal cancer wer...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.10.006
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:Preterm birth is associated with gastric acid-related disorders in infancy, but no investigators have examined this association beyond early childhood. We used antisecretory medication data to explore whether preterm birth is associated with gastric acid-related disorders in young adulthood. METHODS:We conduct...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2012.02.006
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To examine the association between folic acid (FA) supplementation obtained through either single FA tablets or multivitamins (MVs) and menstrual cycle characteristics among 5386 women aged 18-40 years, enrolled in an Internet-based study of Danish women attempting pregnancy during 2007-2011. METHODS:In a cros...
journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2015-10-01 00:00:00
abstract:PURPOSE:We sought to examine the importance of childhood circumstances, adult socioeconomic status, and material circumstances to physical and mental functioning among middle-aged women and men. METHODS:The data were collected among the employees of the City of Helsinki by mailed questionnaires from 2000 to 2002 (7148...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2006.11.003
更新日期:2007-06-01 00:00:00
abstract::A study of blood lipid levels in adolescent students in rural and urban areas of Greece was undertaken. Blood samples were drawn from 307 adolescents aged 12 to 18 years attending two rural and two urban high schools of different socioeconomic level (urban/lower, urban/higher). Obesity among adolescents had statistica...
journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:1995-07-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.07.006
更新日期:2011-12-01 00:00:00
abstract::Some of the readjustment problems of Vietnam veterans have been attributed to posttraumatic stress disorder (PTSD). This case-control study compared demographic and military characteristics of 374 Vietnam veterans who had PTSD with 373 healthy Vietnam veterans. Veterans were chosen from the Agent Orange Registry, a De...
journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:1991-11-01 00:00:00
abstract:PURPOSE:We aim to shed light on progress in cancer medicine through studying time trends in age-specific rates of cancer incidence and mortality over the last quarter century. METHODS:We analyzed age-specific incidence and mortality rates of all cancer sites combined using the high-quality population-based databases o...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.04.007
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:Cost analyses of tuberculosis (TB) in the United States have not included elements that may be prevented if TB were prevented, such as losses associated with TB-related disability, personal and other costs to society. Unmeasured TB costs lead to underestimates of the benefit of prevention and create conditions ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2009.09.004
更新日期:2010-01-01 00:00:00
abstract::Serum total cholesterol (> or = 6.7 mmol/L) measured in 1960 in the Charleston Heart Study cohort was found to be a risk for mortality from coronary heart disease during the period of 1960 to 1988 in white men (relative risk [RR] 1.5; 95% confidence interval [CI]: 1.1, 2.2), white women (RR 1.7; 95% CI: 1.1, 2.7), and...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:To examine the mortality risk associated with diabetes in the Mexico City Diabetes Study (MCDS) and the San Antonio Heart Study (SAHS). METHODS:Prospective cohorts conducted 1990-2007 in MCDS and 1979-2000 in SAHS. Mortality risk was examined using Cox proportional hazard models in 1402 non-Hispanic whites (NH...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.07.003
更新日期:2011-12-01 00:00:00
abstract::PURPOSE: Evaluating the impact of population-based rehabilitation interventions for work-related low back disorders (WR-LBD) requires job exposure factors to be considered as time-varying covariates. The role of job factors in recovery has not been well-established as most studies are based upon clinic samples, not wo...
journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2000-10-01 00:00:00
abstract:PURPOSE:To test the hypothesis that high unemployment predicts reduced detection of local breast tumors among African American and non-Hispanic white women in the Detroit, Michigan and Atlanta, Georgia SEER catchment areas. METHODS:We test the hypothesis with data for the 156 months from January 1985 through December ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(02)00273-9
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:To examine associations between racial discrimination, mood disorders, and cardiovascular disease (CVD) among Black Americans. METHODS:Weighted logistic regression analyses were performed on a nationally representative sample of Black Americans (n = 5022) in the National Survey of American Life (NSAL; 2001-200...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.10.009
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:Prospective evidence suggests an inverse association between socioeconomic circumstances in childhood and adolescence and blood pressure (BP) in adulthood, but uncertainty remains about whether this association is confounded by risk factors acting in utero, early infancy, and adulthood. The authors investigated...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2006.01.004
更新日期:2006-10-01 00:00:00