Comparison of EXIT-25 and the Frontal Assessment Battery for evaluation of executive dysfunction in patients attending a memory clinic.

abstract：:The current increase in aged individuals in number and proportion of the general population warrants dependable strategies to improve early detection of cognitive impairment. It was the goal of the present study to develop a triage for bedside testing and outpatient services. In a prospective clinical cohort study at ...

journal_title：Dementia and geriatric cognitive disorders

authors： Beinhoff U,Hilbert V,Bittner D,Gron G,Riepe MW

更新日期：2005-01-01 00:00:00

abstract：:Primary central nervous system lymphoma (PCNSL) usually presents with clinical and neuroimaging findings consistent with single or multiple intracranial mass lesions. On cranial magnetic resonance imaging (MRI), such lesions are nearly always contrast enhancing, reflecting disruption of the blood-brain barrier at the ...

journal_title：Dementia and geriatric cognitive disorders

authors： Bakshi R,Mazziotta JC,Mischel PS,Jahan R,Seligson DB,Vinters HV

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND/AIMS:Prior studies have shown that patients with dementia are at risk of receiving insufficient treatment for pain after a hip fracture. We therefore hypothesized that elderly hip fracture patients with dementia received less postoperative pain treatment than those without dementia. METHOD:All patients (age...

journal_title：Dementia and geriatric cognitive disorders

authors： Jensen-Dahm C,Palm H,Gasse C,Dahl JB,Waldemar G

更新日期：2016-01-01 00:00:00

abstract：:Age-related changes and the effects of dementia of the Alzheimer type (DAT) were investigated during a visual orienting attention task in which attention was pre-cued to one or other hemifields. Central cues were either valid, neutral, invalid or NoGo (inhibitory). The response time cost-benefit analysis showed a decr...

journal_title：Dementia and geriatric cognitive disorders

authors： Wright M,Geffen G,Geffen L

更新日期：1997-11-01 00:00:00

abstract：:The Fas antigen (CD95) is a cell surface receptor that mediates cell apoptosis signalling. Recent investigations have shown that Fas-regulated apoptosis was linked to neurodegenerative lesions in the brain of patients with Alzheimer's disease (AD). Here data regarding the association of two polymorphisms of the Fas pr...

journal_title：Dementia and geriatric cognitive disorders

authors： Chiappelli M,Nasi M,Cossarizza A,Porcellini E,Tumini E,Pinti M,Troiano L,Franceschi M,Licastro F

更新日期：2006-01-01 00:00:00

abstract：:Although myoclonus commonly occurs in a later stage of Alzheimer's disease (AD), the pathological basis of this symptom is still unclear. In order to elucidate the neuropathological substrate of myoclonus in AD, we quantitatively assessed neuronal density and volume, with a discrimination between small and large neuro...

journal_title：Dementia and geriatric cognitive disorders

authors： Fukutani Y,Cairns NJ,Everall IP,Chadwick A,Isaki K,Lantos PL

更新日期：1999-03-01 00:00:00

abstract：:Data were derived from the Cochrane Collaboration meta-analyses of the efficacies of ginkgo, donepezil, rivastigmine and galantamine on changes in cognitive function in patients with dementia and, where necessary, were transformed to standardized mean differences. The proportion of patients discontinuing trials was us...

journal_title：Dementia and geriatric cognitive disorders

authors： Kurz A,Van Baelen B

更新日期：2004-01-01 00:00:00

abstract：:Ten years after the introduction of the first drug, tacrine, in the treatment of Alzheimer's disease, it seems appropriate to re-appraise the pharmacological processes of innovation in the research field of dementia. The aim of this review is to pinpoint concrete improvements achieved in this field, regarding experime...

journal_title：Dementia and geriatric cognitive disorders

authors： Sellal F,Nieoullon A,Michel G,Michel BF,Lacomblez L,Geerts H,Delini Stula A,Bordet R,Bentué-Ferrer D,Allain H

更新日期：2005-01-01 00:00:00

abstract：:The H63D mutation in the hemochromatosis gene (HFE) has recently been considered as a risk factor in Alzheimer's disease (AD) with advancing age at onset of the disease, independently of the apolipoprotein E (ApoE) epsilon4 allele effect. We examined the distribution of the H63D mutation and ApoE genotypes as a functi...

journal_title：Dementia and geriatric cognitive disorders

authors： Combarros O,García-Román M,Fontalba A,Fernández-Luna JL,Llorca J,Infante J,Berciano J

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Bright light treatment is a therapeutic intervention mainly used to treat sleep and circadian disturbances in Alzheimer's disease (AD) patients. Recently, a handful of studies also focused on the effect on cognition and behavior. Conflicting findings are reported in the literature, and no definite conclusion...

journal_title：Dementia and geriatric cognitive disorders

authors： Mitolo M,Tonon C,La Morgia C,Testa C,Carelli V,Lodi R

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Older people undergoing surgery are at risk of developing postoperative cognitive dysfunction (POCD), but little is known of risk factors predisposing patients to POCD. Our objective was to estimate the risk of POCD associated with exposure to preoperative diabetes, hypertension, and obesity. METHODS:O...

journal_title：Dementia and geriatric cognitive disorders

authors： Lachmann G,Feinkohl I,Borchers F,Ottens TH,Nathoe HM,Sauer AM,Dieleman JM,Radtke FM,van Dijk D,Spies C,Pischon T

更新日期：2018-01-01 00:00:00

abstract：:Mild cognitive impairment (MCI) is regarded as a precursor to dementia, but not all patients with MCI develop dementia. We followed up 165 elderly outpatients with MCI for a mean of 3 years. The aims were (1) to investigate the risk of conversion to dementia for different MCI subtypes diagnosed according to standardiz...

journal_title：Dementia and geriatric cognitive disorders

authors： Ravaglia G,Forti P,Maioli F,Martelli M,Servadei L,Brunetti N,Pantieri G,Mariani E

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:Existing cognitive measures for moderate-to-severe dementia have shown floor effects and an inability to assess the remaining cognitive function, especially for profound dementia. METHODS:We constructed the Cognitive Test for Severe Dementia (CTSD), which consists of 13 items covering 7 cognitive domai...

journal_title：Dementia and geriatric cognitive disorders

authors： Tanaka H,Nagata Y,Uematsu M,Takebayashi T,Hanada K,Inokawa M,Fukuhara K,Ogawa Y,Haga D,Kakegawa Y,Nishikawa T

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the decline in specific neuropsychological functions in nondemented Parkinson's disease (PD) patients with a history of visual hallucinations (VH). METHODS:Twenty PD patients with VH, 20 PD patients without VH and 18 normal controls were followed up over a 1-year period and assessed for cognitive...

journal_title：Dementia and geriatric cognitive disorders

authors： Ramirez-Ruiz B,Junque C,Marti MJ,Valldeoriola F,Tolosa E

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Possession of one or more apolipoprotein E (APOE) epsilon4 alleles may influence the distribution of atrophy and clinical phenotype. We aimed to assess the influence of APOE genotype on cortical thickness and regional brain volumes in AD (Alzheimer's disease). METHODS:We included 38 patients (9 epsilon4 non...

journal_title：Dementia and geriatric cognitive disorders

authors： Gutiérrez-Galve L,Lehmann M,Hobbs NZ,Clarkson MJ,Ridgway GR,Crutch S,Ourselin S,Schott JM,Fox NC,Barnes J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Lacunar stroke (L) is the most common stroke subtype associated with vascular dementia (VaD-L). OBJECTIVE:To evaluate the cognitive and behavioral course in patients with probable VaD-L. METHODS:We longitudinally measured rates of change on MMSE, digit span, logical memory, Controlled Oral Word Association...

journal_title：Dementia and geriatric cognitive disorders

authors： Aharon-Peretz J,Daskovski E,Mashiach T,Kliot D,Tomer R

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:We purposed to investigate the relationship between cerebral abnormalities detected by magnetic resonance imaging (MRI) and cognitive performance in nondemented outpatients with heart failure (HF). METHODS:In 58 patients with HF neuropsychological assessment was performed including tests of mental spee...

journal_title：Dementia and geriatric cognitive disorders

authors： Vogels RL,Oosterman JM,van Harten B,Gouw AA,Schroeder-Tanka JM,Scheltens P,van der Flier WM,Weinstein HC

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Estimations of life expectancies (LE) in health and ill health are important for planning future health care support. This study aimed at quantifying whether an increased LE is accompanied by an increase in the duration of life with dementia (DemLE) in Hong Kong SAR. METHODS:Two parameters from a logistic m...

journal_title：Dementia and geriatric cognitive disorders

authors： Cheung SL,Yip SF,Branch LG,Robine JM

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To investigate the neural basis for the behavioral symptoms of frontotemporal lobar degeneration (FTLD) that cause the greatest caregiver distress. BACKGROUND:FTLD is a progressive neurodegenerative disease associated with behavioral disturbances. Group studies have related these behaviors to volume loss on ...

journal_title：Dementia and geriatric cognitive disorders

authors： Massimo L,Powers C,Moore P,Vesely L,Avants B,Gee J,Libon DJ,Grossman M

更新日期：2009-01-01 00:00:00

abstract：AIMS:To perform an item analysis of the Montreal Cognitive Assessment (MoCA) versus the Mini-Mental State Examination (MMSE) in the prediction of cognitive impairment, and to examine the characteristics of different MoCA threshold scores. METHODS:135 subjects enrolled in a longitudinal clinicopathologic study were adm...

journal_title：Dementia and geriatric cognitive disorders

authors： Damian AM,Jacobson SA,Hentz JG,Belden CM,Shill HA,Sabbagh MN,Caviness JN,Adler CH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIM:The prevalence of cognitive symptoms in recently diagnosed Parkinson's disease (PD) patients may be as high as 60%. We report a novel deep brain stimulation (DBS) strategy targeting both motor and cognitive symptoms. METHODS:A PD patient diagnosed with mild cognitive impairment underwent DBS surgery tar...

journal_title：Dementia and geriatric cognitive disorders

authors： Nombela C,Lozano A,Villanueva C,Barcia JA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Hypovitaminosis D is associated with executive dysfunction as a whole. The purpose of this cross-sectional study was to determine whether lower vitamin D levels were associated with mental flexibility, information updating, or cognitive and motor inhibition among older adults. METHODS:One hundred Caucasian ...

journal_title：Dementia and geriatric cognitive disorders

authors： Annweiler C,Maby E,Meyerber M,Beauchet O

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Since detection of the prion protein gene (PRNP) more than 30 mutations have been discovered. Some have only been found in single case reports without known intrafamilial accumulation or neuropathological proof so that the causal connection between mutation and disease could not be proved. Those patient...

journal_title：Dementia and geriatric cognitive disorders

authors： Schelzke G,Stoeck K,Eigenbrod S,Grasbon-Frodl E,Raddatz LM,Ponto C,Kretzschmar HA,Zerr I

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the potential impact of vascular risk factors including copeptin - a robust surrogate marker of arginine vasopressin associated with the metabolic syndrome and diabetes risk - on future cognitive abilities in a population-based cohort. METHODS:Participants (n = 933) were investigated using ...

journal_title：Dementia and geriatric cognitive disorders

authors： Tufvesson E,Melander O,Minthon L,Persson M,Nilsson PM,Struck J,Nägga K

更新日期：2013-01-01 00:00:00

abstract：:We compared the intact alpha7 nicotinic acetylcholine receptor (alpha7nAChR) protein levels in the peripheral blood leukocytes in 15 Alzheimer's disease (AD) patients and 13 normal elderly control subjects. Demographic data and Mini-Mental State Examination (MMSE) scores were obtained. Western blot analysis for alpha7...

journal_title：Dementia and geriatric cognitive disorders

authors： Chu LW,Ma ES,Lam KK,Chan MF,Lee DH

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To study undiagnosed diseases in older people with and without dementia. DESIGN:Cross-sectional population-based study in Lieto, southwestern Finland. PARTICIPANTS:All the inhabitants aged 64 and more in Lieto. Participation rate was 82% (n = 1,260). MEASUREMENTS:Dementia and its subtypes were diagnosed ac...

journal_title：Dementia and geriatric cognitive disorders

authors： Löppönen MK,Isoaho RE,Räihä IJ,Vahlberg TJ,Loikas SM,Takala TI,Puolijoki H,Irjala KM,Kivelä SL

更新日期：2004-01-01 00:00:00

abstract：:A substantive overlap between the clinical syndromes of frontal lobe dementia (FLD), frontotemporal dementia (FTD), or primary progressive aphasia (PPA), and corticobasal degeneration syndrome (CBDS) has been demonstrated in a population of 55 patients followed for more than 3 years in a cognitive neurology clinic. Pa...

journal_title：Dementia and geriatric cognitive disorders

authors： Kertesz A,Davidson W,Munoz DG

更新日期：1999-01-01 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptor dysfunction has been implicated in the pathogenesis of Alzheimer's disease (AD). The NMDA receptor is composed of several subunits, of which the receptor 2b subunit (NR2b) is of particular significance for AD. Abundant in the hippocampus of normal subjects, reductions in NR2b have ...

journal_title：Dementia and geriatric cognitive disorders

authors： Tsai SJ,Liu HC,Liu TY,Cheng CY,Hong CJ

更新日期：2002-01-01 00:00:00

abstract：:Frontotemporal dementia (FTD) and Alzheimer's disease (AD) are two frequent causes of dementia that share both clinical and neuropathological features. Common to both disorders are the neurofibrillary tangles consisting of aggregations of hyperphosphorylated tau protein. Recently, a number of different pathogenic muta...

journal_title：Dementia and geriatric cognitive disorders

authors： Ostojic J,Elfgren C,Passant U,Nilsson K,Gustafson L,Lannfelt L,Froelich Fabre S

更新日期：2004-01-01 00:00:00

abstract：:Antiphospholipid antibodies (aPLAb) may cause both focal ischemic and diffuse brain damage and may be associated with dementia. We have examined the relationship of aPLAb to dementia in the elderly. Blood samples were obtained from 87 consecutive patients with dementia (74 +/- 11 years old) and 69 controls (78 +/- 9 y...

journal_title：Dementia and geriatric cognitive disorders

authors： Mosek A,Yust I,Treves TA,Vardinon N,Korczyn AD,Chapman J

更新日期：2000-01-01 00:00:00