Cognitive changes in Parkinson's disease patients with visual hallucinations.

abstract：:The two most frequently examined biomarkers in the diagnosis of dementia are cerebrospinal fluid (CSF) tau and beta-amyloid(1-42) (Abeta(1-42)). An assay for tau phosphorylated at threonine 181 (phospho-tau) has recently been developed. We studied these three markers in patients with possible Alzheimer's disease (AD; ...

journal_title：Dementia and geriatric cognitive disorders

authors： Nägga K,Gottfries J,Blennow K,Marcusson J

更新日期：2002-01-01 00:00:00

abstract：AIM:The aims of the present study were to report on the psychometric properties of the Pain Assessment in Advanced Dementia (PAINAD) scale by comparing it with the gold standard method of self-reporting on a numerical rating scale (NRS), and to provide a categorical version of the PAINAD scale comparable with the verba...

journal_title：Dementia and geriatric cognitive disorders

authors： Mosele M,Inelmen EM,Toffanello ED,Girardi A,Coin A,Sergi G,Manzato E

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Although QOL is an important indicator to assess multiple facets of life, the QOL of Alzheimer's disease (AD) subjects with impaired cognitive ability due to dementia has not yet been fully investigated. In this study, we developed the Japanese version of the Quality of Life-Alzheimer's disease (QOL-AD) scal...

journal_title：Dementia and geriatric cognitive disorders

authors： Matsui T,Nakaaki S,Murata Y,Sato J,Shinagawa Y,Tatsumi H,Furukawa TA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed to investigate whether the serial position effects in memory can differentiate patients with different subtypes of mild cognitive impairment (MCI) from healthy controls and patients with different stages of Alzheimer's disease (AD). METHODS:The serial position effects was tested with t...

journal_title：Dementia and geriatric cognitive disorders

authors： Moser B,Deisenhammer EA,Marksteiner J,Papousek I,Fink A,Weiss EM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The apolipoprotein E (APOE) e4 genetic polymorphism is a major risk factor for Alzheimer' s disease, hence the possible prevention of its detrimental effects on cognition is of high relevance. METHODS:We used linear regression models to assess associations of APOE e4 with cognitive performance in a populati...

journal_title：Dementia and geriatric cognitive disorders

authors： Perna L,Mons U,Rujescu D,Kliegel M,Brenner H

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To detect the main factors associated with the occurrence of specific geriatric syndromes (namely pressure sores, fecal incontinence, urinary incontinence and falls) in elderly patients during hospitalization. DESIGN:Observational prospective study. SETTING:Eighty-one community and university hospitals thro...

journal_title：Dementia and geriatric cognitive disorders

authors： Mecocci P,von Strauss E,Cherubini A,Ercolani S,Mariani E,Senin U,Winblad B,Fratiglioni L

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Catechol-O-methyltransferase, encoded by the COMT gene, is one of the enzymes that degrade dopamine. The aim of this study was to investigate whether polymorphisms in the COMT gene were associated with delirium. METHODS:Patients aged 65 years and older, acutely admitted to the medical department or to ...

journal_title：Dementia and geriatric cognitive disorders

authors： van Munster BC,Baas F,Tanck MW,de Rooij SE

更新日期：2011-01-01 00:00:00

abstract：:The apolipoprotein E (APOE) gene epsilon 4 allele is known to be associated with late-onset familial and sporadic Alzheimer's disease (AD). We assessed the possible relationship between APOE genotypes and morphological or functional changes in AD brains by x-ray computed tomography (CT), magnetic resonance imaging (MR...

journal_title：Dementia and geriatric cognitive disorders

authors： Tanaka S,Kawamata J,Shimohama S,Akaki H,Akiguchi I,Kimura J,Ueda K

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between quantitative EEG (qEEG) measurements in frontotemporal dementia (FTD), Alzheimer's disease (AD) and healthy controls and to study to what extent qEEG in FTD and AD or neuropsychological test results of FTD and AD patients or a combination of both contribute to classific...

journal_title：Dementia and geriatric cognitive disorders

authors： Lindau M,Jelic V,Johansson SE,Andersen C,Wahlund LO,Almkvist O

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:We identified and studied 13 patients carrying the P301L mutation in the MAPT gene from the same area (Baix Llobregat County) in Barcelona, Spain. METHODS:The demographic and clinical features were reviewed retrospectively. Detailed neuropathological characterization was obtained in 9 subjects. To inve...

journal_title：Dementia and geriatric cognitive disorders

authors： Borrego-Écija S,Morgado J,Palencia-Madrid L,Grau-Rivera O,Reñé R,Hernández I,Almenar C,Balasa M,Antonell A,Molinuevo JL,Lladó A,Martínez de Pancorbo M,Gelpi E,Sánchez-Valle R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Differences in the gross shape of the corpus callosum (CC) and its subregional areas were investigated on brain MRI of patients with probable Alzheimer's disease (AD) and age- and gender-matched healthy normal control subjects. The AD patients differed from the normal control subjects in terms of a more...

journal_title：Dementia and geriatric cognitive disorders

authors： Tomaiuolo F,Scapin M,Di Paola M,Le Nezet P,Fadda L,Musicco M,Caltagirone C,Collins DL

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) and frontotemporal dementia (FTD) are two common forms of primary neurodegenerative dementia. Mutations in 3 genes (PSEN1, PSEN2, and APP) have been identified in patients with early-onset AD. METHODS:We performed gene sequencing in PSEN1, PSEN2, and APP in 61 AD and 35 FTD Chinese ...

journal_title：Dementia and geriatric cognitive disorders

authors： Shi Z,Wang Y,Liu S,Liu M,Liu S,Zhou Y,Wang J,Cai L,Huo YR,Gao S,Ji Y

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:To characterize loss of basic activities of daily living (BADL) in 687 Alzheimer's disease (AD) community-dwelling patients included in the French REAL cohort. METHODS:Patients had mild to moderately severe AD, and the mean age was 77.8 years. Patterns of loss of the 6 BADL were described at inclusion ...

journal_title：Dementia and geriatric cognitive disorders

authors： Lechowski L,Van Pradelles S,Le Crane M,d'Arailh L,Tortrat D,Teillet L,Vellas B,REAL Group.

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:With an increasing life expectancy, the number of people suffering from dementia globally will rise to about 115.4 million by 2050. It is projected that in the 21st century, the majority of the world's older people will be living in Asia. This paper examines the global issues of family caregiving for ol...

journal_title：Dementia and geriatric cognitive disorders

authors： Chan SW

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Given the poorer prognosis of Alzheimer's disease (AD) patients with rapid cognitive decline (RCD), there is a need for a clinical assessment tool to detect these patients. OBJECTIVE:To investigate if there is a Mini Mental State Examination (MMSE) threshold of decline during 6 months of follow-up which pre...

journal_title：Dementia and geriatric cognitive disorders

authors： Soto ME,Andrieu S,Cantet C,Reynish E,Ousset PJ,Arbus C,Gillette-Guyonnet S,Nourhashémi F,Vellas B,REAL.FR group.

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIM:The prevalence of cognitive symptoms in recently diagnosed Parkinson's disease (PD) patients may be as high as 60%. We report a novel deep brain stimulation (DBS) strategy targeting both motor and cognitive symptoms. METHODS:A PD patient diagnosed with mild cognitive impairment underwent DBS surgery tar...

journal_title：Dementia and geriatric cognitive disorders

authors： Nombela C,Lozano A,Villanueva C,Barcia JA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIM:To estimate the prevalence of Alzheimer's disease (AD) treatment in Aragon (Spain), analyzing differences according to age, gender and health area. METHODS:Retrospective study on AD treatment prevalence of cholinesterase inhibitors and memantine during 2005, using pharmaco-epidemiological data from pres...

journal_title：Dementia and geriatric cognitive disorders

authors： Villar-Fernández I,Bjerrum L,Feja C,Rabanaque MJ

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To study undiagnosed diseases in older people with and without dementia. DESIGN:Cross-sectional population-based study in Lieto, southwestern Finland. PARTICIPANTS:All the inhabitants aged 64 and more in Lieto. Participation rate was 82% (n = 1,260). MEASUREMENTS:Dementia and its subtypes were diagnosed ac...

journal_title：Dementia and geriatric cognitive disorders

authors： Löppönen MK,Isoaho RE,Räihä IJ,Vahlberg TJ,Loikas SM,Takala TI,Puolijoki H,Irjala KM,Kivelä SL

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND/AIMS:The relationship between subcortical hyperintensities (SH) on brain MRI and gait parameters in aging and Alzheimer's disease (AD) is unclear. This study compared gait in 42 mild AD patients to 22 normal controls (NC) based on their SH severity and correlated them to SH burden in these groups. METHODS:G...

journal_title：Dementia and geriatric cognitive disorders

authors： Nadkarni NK,McIlroy WE,Mawji E,Black SE

更新日期：2009-01-01 00:00:00

abstract：:There is growing evidence for a role of apoptosis in Alzheimer's disease (AD). Recent findings suggest an increased susceptibility of lymphocytes to apoptosis in AD. To prove the hypothesis of systemic alterations in the apoptotic balance in AD, serum and cerebrospinal fluid levels of soluble CD95, which is known to m...

journal_title：Dementia and geriatric cognitive disorders

authors： Richartz E,Noda S,Schott K,Günthner A,Lewczuk P,Bartels M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Among the different quantitative electroencephalographic markers, theta activity is known to reflect neural resources involved in memory processes and directed attention. Previous studies suggested that synchronization likelihood analysis in theta-band frequency might be a sensitive method to identify early ...

journal_title：Dementia and geriatric cognitive disorders

authors： Missonnier P,Gold G,Herrmann FR,Fazio-Costa L,Michel JP,Deiber MP,Michon A,Giannakopoulos P

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:The beta amyloid aggregations present in Alzheimer's disease affect neurons through various toxic alterations. The aim of this study was to determine the expression of the vitamin D receptor (VDR), 25-hydroxyvitamin D3 24-hydroxylase (an accelerator of vitamin D catabolism), and the L-type voltage-sensi...

journal_title：Dementia and geriatric cognitive disorders

authors： Dursun E,Gezen-Ak D,Yilmazer S

更新日期：2013-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is generally understood as primarily affecting cognition while sparing motor function, at least until the later stages of the disease. Studies reported over the past 10 years, however, have documented a prevalence of falls in AD patients significantly higher than in age-matched normal elders; ...

journal_title：Dementia and geriatric cognitive disorders

authors： Sheridan PL,Hausdorff JM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The Clinical Dementia Rating Scale (CDR) is used to rate dementia severity. Its utility in diagnosing mild cognitive impairment (MCI) and its predictive value remain unknown. AIMS:The aim of this study was to examine the association between CDR scores and expert MCI diagnosis, and to determine whether basel...

journal_title：Dementia and geriatric cognitive disorders

authors： Woolf C,Slavin MJ,Draper B,Thomassen F,Kochan NA,Reppermund S,Crawford JD,Trollor JN,Brodaty H,Sachdev PS

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:The prevalence of mild cognitive impairment (MCI) and its subtypes among Chinese older adults, and the contribution of vascular risk factors (VRF) and vascular disorders to MCI remain unclear. This study aims to investigate the prevalence of MCI and its different subtypes, and clarify the role of VRF an...

journal_title：Dementia and geriatric cognitive disorders

authors： Ma F,Wu T,Zhao J,Ji L,Song A,Zhang M,Huang G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:We purposed to investigate the relationship between cerebral abnormalities detected by magnetic resonance imaging (MRI) and cognitive performance in nondemented outpatients with heart failure (HF). METHODS:In 58 patients with HF neuropsychological assessment was performed including tests of mental spee...

journal_title：Dementia and geriatric cognitive disorders

authors： Vogels RL,Oosterman JM,van Harten B,Gouw AA,Schroeder-Tanka JM,Scheltens P,van der Flier WM,Weinstein HC

更新日期：2007-01-01 00:00:00

abstract：UNLABELLED:The concept of the cognitive reserve (CR) hypothesizes that premorbid factors such as education enable compensation for the manifestation of brain pathology. Accordingly, pathology should be more prominent in individuals with higher CR before becoming clinically apparent. Previously, we found that patients s...

journal_title：Dementia and geriatric cognitive disorders

authors： Rolstad S,Nordlund A,Eckerström C,Gustavsson MH,Zetterberg H,Wallin A

更新日期：2009-01-01 00:00:00

abstract：:Frontotemporal dementia (FTD) is often misdiagnosed as Alzheimer's disease (AD). We hypothesized that the first symptoms associated with FTD would be different from those seen in AD and that the first symptoms in FTD would reflect loss of function in the frontal region with the greatest degree of degeneration. The obj...

journal_title：Dementia and geriatric cognitive disorders

authors： Lindau M,Almkvist O,Kushi J,Boone K,Johansson SE,Wahlund LO,Cummings JL,Miller BL

更新日期：2000-09-01 00:00:00

abstract：:Findings in patients with dementia of the Alzheimer type (AD patients) concerning the enactment effect, i.e. reaching a better memory performance after encoding actions by performing them in contrast to encoding them by reading, are ambiguous. In order to get more insight into memory deterioration in patients sufferin...

journal_title：Dementia and geriatric cognitive disorders

authors： Mack W,Eberle C,Frölich L,Knopf M

更新日期：2005-01-01 00:00:00

abstract：AIMS:We aimed to establish the prevalence of depression among recently admitted long-term care patients and to examine associations with diagnostic initiatives and treatment as recorded in patients' medical records. MATERIALS AND METHODS:Eighty-eight long-term care patients were included. Depression was diagnosed acco...

journal_title：Dementia and geriatric cognitive disorders

authors： Iden KR,Engedal K,Hjorleifsson S,Ruths S

更新日期：2014-01-01 00:00:00