Extraction of glycyrrhizic acid and glabridin from licorice.

Abstract:

:The extraction and separation conditions of glycyrrhizic acid and glabridin from licorice were investigated. By changing the different extraction solvents, procedures, times and temperature, the optimum extraction condition was established: the used of ethanol/water (30:70, v/v) as an extraction solvent, and 60 min dipping time under 50 degrees C. The extracts of licorice were separated and determined by reversed-phase high performance liquid chromatography with a methanol/water (70:30, v/v, containing 1% acetic acid) as the mobile phase. Under the optimum extraction condition, 2.39 mg/g of glycyrrhizic acid and 0.92 mg/g of glabridin were extracted from Chinese licorice and the recoveries were 89.7% and 72.5% respectively.

journal_name

Int J Mol Sci

authors

Tian M,Yan H,Row KH

doi

10.3390/ijms9040571

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

571-7

issue

4

issn

1422-0067

journal_volume

9

pub_type

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