Abstract:
:Recently, extreme ultraviolet (EUV) radiation has been increasingly used to modify polymers. Properties such as the extremely short absorption lengths in polymers and the very strong interaction of EUV photons with materials may play a key role in achieving new biomaterials. The purpose of the study was to examine the impact of EUV radiation on cell adhesion to the surface of modified polymers that are widely used in medicine: poly(tetrafluoroethylene) (PTFE), poly (vinylidene fluoride) (PVDF), and poly-L-(lactic acid) (PLLA). After EUV surface modification, which has been performed using a home-made laboratory system, changes in surface wettability, morphology, chemical composition and cell adhesion polymers were analyzed. For each of the three polymers, the EUV radiation differently effects the process of endothelial cell adhesion, dependent of the parameters applied in the modification process. In the case of PVDF and PTFE, higher cell number and cellular coverage were obtained after EUV radiation with oxygen. In the case of PLLA, better results were obtained for EUV modification with nitrogen. For all three polymers tested, significant improvements in endothelial cell adhesion after EUV modification have been demonstrated.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Lech A,Butruk-Raszeja BA,Ciach T,Lawniczak-Jablonska K,Kuzmiuk P,Bartnik A,Wachulak P,Fiedorowicz Hdoi
10.3390/ijms21249679subject
Has Abstractpub_date
2020-12-18 00:00:00issue
24issn
1422-0067pii
ijms21249679journal_volume
21pub_type
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