The skin microflora and the formation of human axillary odour.

Abstract:

:Synopsis We have examined the relationship between human axillary skin microflora and underarm odour (UAO), in particular, the ability of cutaneous bacteria to transform steroids. A study was made of bacterial population density and odour intensity of the axillae of 34 normal male subjects. There was a statistically significant association between population density of aerobic coryneform bacteria and UAO intensity. No associations could be found between population densities of staphylococci, micrococci or propionibacteria and UAO intensity. An in vitro model for formation of UAO was developed, and used to test individual bacterial isolates. Only aerobic coryneforms could produce axillary odour in vitro, most notably C. xerosis. Many aerobic coryneforms could transform testosterone, the principal metabolites being 5alpha- and 5beta-DHT, androstenedione, and 5alpha- and 5beta-androstanedione. UAO positive coryneforms were more metabolically active than UAO negative bacteria. Micrococci also transformed testosterone to androstenedione, whilst staphylococci and propionibacteria could not metabolize it. A hypothesis for the role of aerobic coryneforms in the formation of human axillary odour is discussed.

journal_name

Int J Cosmet Sci

authors

Rennie PJ,Gower DB,Holland KT,Mallet AI,Watkins WJ

doi

10.1111/j.1467-2494.1990.tb00535.x

subject

Has Abstract

pub_date

1990-10-01 00:00:00

pages

197-207

issue

5

eissn

0142-5463

issn

1468-2494

pii

ICS197

journal_volume

12

pub_type

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