Abstract:
OBJECTIVES:Liposomes are commonly used in cosmetic formulations to increase the bioavailability of active ingredients. We have previously shown that polysaccharide coating of liposomes improves their resistance to surfactants and electrolytes. In the current study, we have assessed the impact of coating on the skin penetration enhancer properties of liposomes. METHODS:The physicochemical properties of coated liposomes (Ionosomes™) were evaluated before and after encapsulation of two different hydrophilic molecules (caffeine and a hexapeptide), and compared to those observed with non-coated liposomes. Moreover, in vitro permeation experiments were performed using Franz™-modified diffusion cells, with normal human skin as membranes. RESULTS:Results showed that both coated and non-coated liposomes significantly improved the bioavailability of hydrophilic active molecules in skin, compared to reference solutions. Although liposome coating slightly reduced entrapment efficiency, the delivery of active molecules was not adversely affected by the process. In conclusion, polysaccharide coating of liposomes allows for better protection of their integrity without compromising the skin bioavailability of the active molecules that they convoy.
journal_name
Int J Cosmet Scijournal_title
International journal of cosmetic scienceauthors
Belhaj N,Arab-Tehrany E,Loing E,Bézivin Cdoi
10.1111/ics.12394subject
Has Abstractpub_date
2017-08-01 00:00:00pages
435-441issue
4eissn
0142-5463issn
1468-2494journal_volume
39pub_type
杂志文章abstract:OBJECTIVE:To evaluate wrinkle improvement and safety of a novel cosmetic dissolving microneedle patches loaded with two active compounds with different hydrophilicities, namely ascorbic acid and retinyl retinoate. METHODS:Clinical studies were performed on 24 Korean women for 12 weeks. Patients in group A were treated...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,随机对照试验
doi:10.1111/ics.12115
更新日期:2014-06-01 00:00:00
abstract::Summary A new instrument has been developed which enables simultaneous determinations of the static and dynamic moduli of elasticity of the stratum corneum to be made. A systematic study of these mechanical parameters for various samples of human SC demonstrates the advantages of the dynamic measurement of the modulus...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1982.tb00321.x
更新日期:1982-12-01 00:00:00
abstract::Singlet-oxygen is a non-radical reactive oxygen species believed to play a major role in many photooxidation processes in connection with diverse photo-biological processes such as skin ageing or photocarcinogenesis. Dimethylmethoxy chromanol (3,4-dihydro-6-hydroxy-2,2-dimethyl-7-methoxy-1(2H)-benzopyran) is a potent ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12039
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:Hyaluronan (HA) plays a role in keratinocyte proliferation and differentiation. In addition, HA has been shown to have different biological activities depending on its molecular weight. It has been reported that HA-mediated CD44 activation regulates keratinocyte differentiation. Therefore, the aim of this stu...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12105
更新日期:2014-02-01 00:00:00
abstract::In the present contribution, the properties of dipropylene glycol isobornyl ether (Pribelance) are discussed, especially in the context of microemulsion and emulsion formulations. Pribelance is a new low-toxic anti-foaming hydrotrope with excellent co-surfactant properties that has some similarities with long-chain al...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2008.00460.x
更新日期:2008-10-01 00:00:00
abstract::Many studies have presented stress-strain relationship of human hair, but most of them have been based on an engineering stress-strain curve, which is not a true representation of stress-strain behaviour. In this study, a more accurate 'true' stress-strain curve of human hair was determined by applying optical techniq...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12031
更新日期:2013-06-01 00:00:00
abstract::On a daily basis, the skin is exposed to many environmental stressors and insults. Over a 24-h natural cycle, during the day, the skin is focused on protection; while at night, the skin is focused on repairing damage that occurred during daytime and getting ready for the next morning. Circadian rhythm provides the pre...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12572
更新日期:2019-12-01 00:00:00
abstract::Cutaneous irritation is a stereotyped response of the skin to any physical or chemical insult. Its main manifestations encompass inflammatory erythema and an alteration of the cutaneous microrelief showing increased roughness, dehydration and erratic desquamation. Several instrumental methods can indirectly assess the...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.2003.00170.x
更新日期:2003-04-01 00:00:00
abstract::The causative substances for axillary osmidrosis, which are often found in apocrine sweat, are the decomposed/denatured products of short-chain fatty acid and other biological metabolite compounds produced by axillary-resident bacteria. Conventional underarm deodorants suppress the process of odour production mostly b...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2006.00322.x
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:A comprehensive methodology for the simultaneous determination of 15 multiclass organic UV filters in sunscreen cosmetics was developed using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). METHODS:Sunscreen cosmetics of various matrices,...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12387
更新日期:2017-08-01 00:00:00
abstract::Skin moisturization is not only important for maintaining skin functional properties but also has great impact on the skin's aesthetic properties. The top layer of the skin, the stratum corneum (SC), plays a key role in protecting and preventing against external aggressions as well as in regulating water flux in and o...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2008.00428.x
更新日期:2008-02-01 00:00:00
abstract::Synopsis We have examined the relationship between human axillary skin microflora and underarm odour (UAO), in particular, the ability of cutaneous bacteria to transform steroids. A study was made of bacterial population density and odour intensity of the axillae of 34 normal male subjects. There was a statistically s...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1990.tb00535.x
更新日期:1990-10-01 00:00:00
abstract::Fading of artificial hair colour has been investigated by simulating actual usage conditions through exposure to artificial radiation in a weatherometer, with 0.35 mW (m(2)nm)(-1) at 340 nm, for 16-48 h, and by periodical washing. Hair colour was produced by using commercial two-part, permanent hair dyes with light au...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2006.00314_3.x
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Mechanical analysis of human hair may provide the dermatologists with several markers of considerable diagnostic importance. The aim of this study was to analyse the physical and mechanical properties of Tunisian women's hair. METHODS:Surface characteristics were determined with scanning electron microscopy...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12313
更新日期:2016-10-01 00:00:00
abstract::Oleuropein, a phenolic compound derived from olive leaves and oil, is known to possess several biological properties, many of which may be attributed to its antioxidant and free radical-scavenging activities. Nevertheless, up to now, the cosmetic activity of this molecule has not been extensively investigated. The aim...
journal_title:International journal of cosmetic science
pub_type: 临床试验,杂志文章
doi:10.1111/j.1468-2494.2008.00424.x
更新日期:2008-04-01 00:00:00
abstract::The vapour pressures of phenethyl alcohol and limonene in their water-in-oil microemulsion region were measured by head space gas chromatography of equilibrated samples. The results showed that the vapour pressure of both fragrance compounds in their mutual solutions without surfactant or water was significantly great...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.1998.177054.x
更新日期:1998-12-01 00:00:00
abstract::Synopsis The ocular irritation potential of 107 cosmetics and toiletries was compared using the rabbit's eye Draize test (IOMA), a cytotoxicity in vitro method (CFIO), and the hen's egg chorioallantoic membrane test (HET-CAM). There was a good correlation between both alternative methods and the Draize test. Non-corre...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1995.tb00124.x
更新日期:1995-10-01 00:00:00
abstract::Hexamidine (HEX) has been used as a preservative in topical preparations since the 1950s. A number of studies also indicate that the molecule plays a beneficial role in skin homoeostasis. In this review, we describe the physicochemical properties of hexamidine diisethionate (HEX D) and the corresponding hydrochloride ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,评审
doi:10.1111/ics.12392
更新日期:2017-08-01 00:00:00
abstract:SYNOPSIS:Despite the extensive use of topical coatings in cosmetics, their effect on the mechanical properties of human skin and the perception of skin tightness in the form of drying stresses is not well understood. We describe the application of a recently developed substrate curvature technique to characterize stres...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2010.00568.x
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:Vitamin C and peptides are widely used in cosmetic products but there is a paucity of clinical studies showing that the formulations are effective in treating signs of facial ageing. These 3 clinical studies evaluated the effectiveness of an anti-ageing formula containing natural vitamin C (10%), biopeptides ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12665
更新日期:2020-10-10 00:00:00
abstract::Sun exposure during leisure activity evokes fatigue. We employed the Advanced Trail Making Test (ATMT), a recently developed objective method of evaluating brain function performance used to measure mental fatigue, for objective determination of fatigue development caused by solar exposure to the human body. First, a ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.0142-5463.2004.00200.x
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Bromelain is a mixture of proteolytic enzymes found in various tissues of the pineapple plant (Ananas comosus) and other species of Bromeliaceae. Owing to its proteolytic activity, bromelain has been used in the food, medical, pharmaceutical and cosmetic industries, for its cell renewal, anti-ageing, whiteni...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12308
更新日期:2016-10-01 00:00:00
abstract::Reduction and prevention of health care-associated infections is a worldwide priority with emphasis on increasing hand hygiene compliance. Repetitive exposure to hand hygiene products and procedures is a significant factor in the development of occupational irritant hand dermatitis. Compliance has been difficult to ac...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,评审
doi:10.1111/j.1468-2494.2012.00733.x
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:The goal of this work was to develop a novel polyurethane polymer coating for the surface of the hair that could be used for style setting via the shape memory effect (SME). The features of the films are in accordance with conventional hair styling methods used in the laboratory. METHODS:In this study, a new...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12294
更新日期:2016-06-01 00:00:00
abstract::It is well established that the evaporation of sweat from the human body surface is the main mechanism by which heat balance is maintained following a rise in body core temperature. Since the introduction of the first brand name antiperspirant in the United States during the early 1900s, antiperspirant products design...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.2003.00184.x
更新日期:2003-08-01 00:00:00
abstract:INTRODUCTION:We report on the preparation and efficacy of 10-hydroxystearic acid (HSA) that improves facial age spots and conspicuous pores. METHODS:The hydration of oleic acid into HSA was catalyzed by the oleate hydratase from Escherichia coli. Following treatment with HSA, collagen type I and type III was assessed ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12529
更新日期:2019-06-01 00:00:00
abstract::The objective of the study was to compare measurements of skin hydration and of biomechanical properties performed on different zones of face and volar forearm. Two short-term (1 h) and two long-term (3 weeks) studies were conducted with a moisturizing and a firming product, respectively, on groups of female volunteer...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2006.00352.x
更新日期:2006-12-01 00:00:00
abstract::Synopsis The absorption of ultraviolet light by a film of sunscreen product on the surface of the skin is considered from a theoretical standpoint. It is apparent that Beer-Lambert's Law would predict protection factors in excess of the actual factors by many orders of magnitude. The possible reasons for this are disc...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1985.tb00417.x
更新日期:1985-10-01 00:00:00
abstract:OBJECTIVES:Facial clinical signs and their integration are the basis of perception than others could have from ourselves, noticeably the age they imagine we are. Facial modifications in motion and their objective measurements before and after application of skin regimen are essential to go further in evaluation capacit...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12198
更新日期:2015-06-01 00:00:00
abstract::Lower eyelid sags as well as wrinkles represent age-related morphological changes of the skin surface. However, a quantitative method to evaluate lower eyelid sagging has not been previously established. We designed a new quantitative evaluation method that uses non-invasive skin scanning, which is based on the differ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2005.00282.x
更新日期:2005-10-01 00:00:00