Abstract:
BACKGROUND:Urethrorectal fistulas (URF) in patients with complex posterior urethral strictures are rare and difficult to repair surgically. There is no widely accepted standard approach described in the published literature. OBJECTIVE:The aim of this study was to describe the outcomes of various operative approaches for the repair of URFs in patients with complex posterior urethral strictures. DESIGN, SETTING, AND PARTICIPANTS:From January 1985 to December 2007, 31 patients (age: 6-61 yr; mean: 28.4) with URFs secondary to posterior urethral strictures were treated using a perineal or combined abdominal transpubic-perineal approach. INTERVENTIONS:A simple perineal approach was used in 4 patients; a transperineal inferior pubectomy approach was used in 18 patients; and a combined transpubic-perineal approach was used in 9 patients. A bulbospongiosus muscle and subcutaneous dartos pedicle flaps were interposed between the repaired rectum and urethra in 22 patients. The combined transpubic-perineal approach used either a gracilis muscle flap (one patient) or a rectus muscle flap (eight patients). MEASUREMENTS:Suprapubic catheterisation was used for bladder drainage, and a urethral silicone stent was left indwelling for 4 wk. RESULTS AND LIMITATIONS:One-stage repair was successful in 4 patients (100%) using the perineal approach, in 16 of 18 patients (88.9%) using the transperineal-inferior pubectomy approach, and in 7 of 9 patients (77.8%) using the transpubic-perineal approach. Recurrent urethral strictures developed in two cases; one patient required regular dilation, and the other patient was treated successfully with tubed perineoscrotal flap urethroplasty. Recurrent URFs developed in two additional patients. CONCLUSIONS:Surgical approaches for the treatment of URFs associated with complex urethral strictures should be based on a number of considerations including the location of the URF, its aetiology, the length of the urethral strictures, and a history of previous unsuccessful repairs. These results demonstrate that the transperineal-inferior pubic approach may be appropriate as a first-line procedure.
journal_name
Eur Uroljournal_title
European urologyauthors
Xu YM,Sa YL,Fu Q,Zhang J,Jin SBdoi
10.1016/j.eururo.2009.02.035subject
Has Abstractpub_date
2010-03-01 00:00:00pages
514-20issue
3eissn
0302-2838issn
1873-7560pii
S0302-2838(09)00230-9journal_volume
57pub_type
杂志文章相关文献
EUROPEAN UROLOGY文献大全abstract:CONTEXT:Overexpression of immune checkpoint molecules affects tumor-specific T-cell immunity in the cancer microenvironment, and can reshape tumor progression and metastasis. Antibodies targeting checkpoints could restore antitumor immunity by blocking the inhibitory receptor-ligand interaction. OBJECTIVE:To analyze d...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2015.02.032
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Muscle-invasive bladder cancer (MIBC) is the second most common genitourinary malignancy, and is associated with high morbidity and mortality. Recently, molecular subtypes of MIBC have been identified, which have important clinical implications. OBJECTIVE:In the current study, we tried to predict the molecu...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2020.04.023
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:The purpose of this retrospective study was to assess complications, voiding patterns, and quality of life in patients with an orthotopic bladder substitution, using an N-shaped ileal neobladder. MATERIALS AND METHODS:Between May 1996 and December 2002, 58 patients (52 men and 6 women) underwent an orthotopic ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2004.12.006
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:To validate a new questionnaire evaluating nocturia, nocturnal enuresis and sleep-interruptions in an elderly population of men and women in Denmark. METHODS:The Nocturia, Nocturnal Enuresis and Sleep-interruption Questionnaire (NNES-Q) emerged from review of the literature and expert consensus. The questio...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2005.11.034
更新日期:2006-04-01 00:00:00
abstract:CONTEXT:Overactive bladder (OAB) treatment guidelines recommend antimuscarinics as first-line pharmacologic therapy. Mirabegron is a first-in-class β3-adrenoceptor agonist licensed for the treatment of OAB and has shown to be well tolerated and effective in the treatment of OAB symptoms. OBJECTIVE:To assess the relativ...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2013.11.010
更新日期:2014-04-01 00:00:00
abstract::HLA antigen type was studied in 55 patients with transitional cell carcinoma of the bladder. The results showed high HLA-B5 and low HLA-BW35 frequencies. Histological grade, stage, and recurrence rate of tumors were also evaluated separately. The results were more significant in recurrent tumors. ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472775
更新日期:1987-01-01 00:00:00
abstract::We report on the conservative management of a renal stab wound by double-J stenting and specific percutaneous arterial embolization in a 34-year-old man. Surgical exploration was avoided because there was a little doubt about the associated intra-abdominal injuries. Recovery was excellent and the patient left the hosp...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471710
更新日期:1991-01-01 00:00:00
abstract::Despite the high cure rate in men with testicular cancer, efforts should be made to diagnose the disease at the preinvasive stage. The disease, which affects young males, is potentially lethal. Furthermore, testicular neoplasia diagnosed at the stage of CIS can be cured without the negative impact on the life-quality ...
journal_title:European urology
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:The development of urothelial malignancy is not solely a consequence of loss of proliferation constraints but also involves loss of cellular differentiation, defined histopathologically as grade. Although tumour grade is an independent prognostic marker for urothelial carcinoma (UC), the molecular events und...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2011.02.022
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:The actual number of transmural sutures needed to ensure a successful fibrin-glued vasovasostomy is a key study parameter of the few experimental works already published. The present work was done to evaluate fibrin-glued vasovasostomy in rats in combination with only 2 transmural sutures. We compared the re...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000019567
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Androgen deprivation therapy (ADT) is associated with increased cardiovascular morbidity. OBJECTIVE:To determine whether cardiovascular morbidity differs following initiation of gonadotropin-releasing hormone (GnRH) agonists compared with an antagonist. DESIGN, SETTING, AND PARTICIPANTS:Pooled data from si...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2013.10.032
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:We compared the detection rates of different transperineal prostate biopsy protocols with the aim to optimize the number of cores to sample according to prostate volume. MATERIAL AND METHODS:From October 2002 to October 2004 we evaluated 480 consecutive patients with PSA between 2.5 and 20 ng/ml undergoing ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2005.08.008
更新日期:2005-12-01 00:00:00
abstract::This case study reports one case of transvaginal natural orifice transluminal endoscopic surgery (NOTES) in a 23-yr-old woman with right flank pain and recurrent urinary tract infection due to a nonfunctional right kidney. She underwent nephrectomy by transvaginal NOTES using the endoscope by vaginal access and two ad...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2007.10.053
更新日期:2008-06-01 00:00:00
abstract::Castration or antiandrogen monotherapies remain options for prostate cancer treatment as only marginal benefits have been demonstrated with combined androgen blockade, although it may be that certain subgroups of patient may benefit. Of the nonsteroidal antiandrogens, bicalutamide 150 mg was as effective as castration...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000052291
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:Evaluating in a retrospective survey the incidence of incidental and symptomatic renal cell carcinoma (RCC) between 1977 and 1994 in the northern part of the Netherlands and the mode of their detection. PATIENTS AND METHODS:Retrospectively, 173 patients surgically treated for RCC were divided into two group...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000052354
更新日期:2000-03-01 00:00:00
abstract::Of 146 patients with superficial bladder carcinoma, 66 (35 primary and 31 recurrent from failure of thiotepa chemoprophylaxis) relapsed following transurethral resection (TUR) and chemotherapy with adriamycin or cis-platinum. A new TUR was carried out. In case of progression in the number of tumors, size, stage or gra...
journal_title:European urology
pub_type: 临床试验,杂志文章
doi:10.1159/000472630
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:Staging in patients with newly diagnosed cancer of the prostate has significant ramifications in the management of the disease. At present, measurement of serum prostate-specific antigen (PSA) concentration and radionuclide bone scintigraphy are two important procedures in the metastatic work-up of these pati...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000019619
更新日期:1998-01-01 00:00:00
abstract::Calcium metabolism was studied in 37 patients with "idiopathic hypercalciuria" on a home diet and after 10 days of low calcium dietary intake (less than 400 mg/24h). After low calcium intake, urinary calcium excretion returned to within normal limits in 70% of the cases. In the group of patients which failed to respon...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473258
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:The extent of lymph node dissection (LND) in bladder cancer (BCa) patients at the time of radical cystectomy may affect oncologic outcome. OBJECTIVE:To evaluate whether extended versus limited LND prolongs recurrence-free survival (RFS). DESIGN, SETTING, AND PARTICIPANTS:Prospective, multicenter, phase-III...
journal_title:European urology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.eururo.2018.09.047
更新日期:2019-04-01 00:00:00
abstract::Prostate cancer is the most common malignancy found in males; however, little is as yet known regarding what initiates the disease. The incidence is highest among American Blacks and lowest in the East Asian population. Subtypes of the disease include familial clustering and a hereditary form (9%) supporting genetic e...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000019910
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of Extracorporeal shock wave lithotripsy (ESWL) in renal anomalies. MATERIAL AND METHODS:From 1991 to May 1995. 53 patients with calculi in anomalous kidneys presented to our clinic for treatment with ESWL. Average patient age was 39 years, a range of 6-66 years. These patients (32 m...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000474472
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:We investigated the potential involvement of the thromboxane A(2) (TXA(2)) pathway in human prostate cancer (PCa). METHODS:Expression of cyclooxygenase-2 (COX-2), TXA(2) synthase (TXS), and TXA(2) receptors (TPRs), the main actors of the TXA(2) pathway, was analyzed on serial tissue sections from 46 human PC...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2006.01.036
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:The effectiveness of a chemotherapy regimen including cisplatin, epirubicin, and estramustine phosphate was evaluated in a series of young patients with prostate cancer. METHODS:28 patients with a histological diagnosis of prostatic carcinoma, age < 70 years, performance status (PS) < 2, hormone-refractory s...
journal_title:European urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000473792
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:International official guidelines recommend urodynamic (UDS) evaluation in patients with pelvic organ prolapse (POP). However, the real benefit of this examination is still the subject of heated and controversial debate. Therefore, we aimed to assess the correlation between urinary symptoms and UDS findings ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2011.03.010
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:New methods for identifying bladder cancer (BCa) progression are required. Gene expression microarrays can reveal insights into disease biology and identify novel biomarkers. However, these experiments produce large datasets that are difficult to interpret. OBJECTIVE:To develop a novel method of microarray ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2009.10.029
更新日期:2010-03-01 00:00:00
abstract::The cancer-related 5-year survival was 80% in 79 patients with penile cancer treated at the Norwegian Radium Hospital from 1974 to 1985 (N0 = 61, N1-2 = 12, N3 = 6). Sentinel node biopsy (SLN) of the inguinal lymph nodes medial to the saphenous vein helps to identify patients with early regional spread. The survival f...
journal_title:European urology
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The advantages and disadvantages of two different methods of analyzing the European Randomized Study of Screening for Prostate Cancer (ERSPC) trial with respect to the effect of prostate-specific antigen (PSA) screening on prostate cancer (PCa) mortality (ie, disease-specific mortality analysis and excess mortality an...
journal_title:European urology
pub_type: 信件
doi:10.1016/j.eururo.2013.12.055
更新日期:2014-09-01 00:00:00
abstract::The multiform biology of superficial bladder tumors, both morphologically and evolutively, and the lack of reliable predictors of progression have led the authors to study the Ag-NOR proteins as a new marker of these tumors. It is well known that particularly the low-grade superficial tumors frequently relapse on the ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000474884
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the role of laparoscopic radical prostatectomy (LRP) and robotic assisted radical prostatectomy (RLRP) based on personal experience and a review of the literature. MATERIAL AND METHODS:Own experience at one European and one American LRP-center includes more than 2000 cases. We performed a MEDLINE...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2005.12.054
更新日期:2006-04-01 00:00:00
abstract::Treatment of localized prostate cancer by ultrasonically guided transperineal 125I implantation, in contrast to open 125I implantation, may allow for ideal distribution of the seeds and may therefore lead to better treatment results. 46 patients with localized prostatic carcinoma (T1-T2, G1-G3, N0, M0) have been treat...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000474797
更新日期:1992-01-01 00:00:00