Incidence of normocalcemic hyperparathyroidism in idiopathic hypercalciuria: evaluation by dietary calcium deprivation test.

Abstract:

:Calcium metabolism was studied in 37 patients with "idiopathic hypercalciuria" on a home diet and after 10 days of low calcium dietary intake (less than 400 mg/24h). After low calcium intake, urinary calcium excretion returned to within normal limits in 70% of the cases. In the group of patients which failed to respond to calcium restriction, TmPO4/GFR values were reduced and, furthermore, in 20% of them plasma iPTH and urinary cAMP levels were increased. These data seem to indicate that: the incidence of absorptive hypercalciuria is higher than hypercalciuria of renal origin; normocalcemic hyperparathyroidism due to primary calcium leak is present only in a limited number of cases, consequently, hypercalciuria secondary to renal phosphate leak is a rather frequent occurrence.

journal_name

Eur Urol

journal_title

European urology

authors

Mazzuoli GF,D'Erasmo E,Minisola S,Mancini D,Malaguti Aliberti L,Scarda A,Bracci U,Miano L

doi

10.1159/000473258

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

331-4

issue

6

eissn

0302-2838

issn

1873-7560

journal_volume

7

pub_type

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