Abstract:
BACKGROUND:International official guidelines recommend urodynamic (UDS) evaluation in patients with pelvic organ prolapse (POP). However, the real benefit of this examination is still the subject of heated and controversial debate. Therefore, we aimed to assess the correlation between urinary symptoms and UDS findings in women with POP through the implementation of a sophisticated computer-based technology in the outpatient workup. DESIGN, SETTING, AND PARTICIPANTS:A prospective cohort study was performed in a single, tertiary, urogynaecologic referral department, enrolling consecutive women seeking care for pelvic floor dysfunctions. INTERVENTION:Patients underwent clinical and urodynamic evaluation. Data regarding baseline characteristics, symptoms, anatomic, and urodynamic findings were gathered for each patient. Multiple linear regression (MLR) and artificial neural networks (ANNs) were performed to design predicting models. RESULTS AND LIMITATIONS:A total of 802 women with POP were included. POP quantification stages and baseline data poorly correlated to final UDS findings. Stress urinary incontinence and overactive bladder were both independently associated to each UDS diagnosis, including detrusor overactivity (DO), urodynamic stress incontinence (USI), and mixed urinary incontinence (USI plus DO). Receiver operating characteristic comparison confirmed that ANNs were more accurate than MLR in identifying predictors of UDS diagnosis, but none of these methods could successfully overcome UDS. Case-control studies are needed to confirm our findings. CONCLUSIONS:Despite the current debate based on the actual value of UDS in women with POP, even the implementation of ANN, a sophisticated computer-based technology, does not permit an accurate diagnosis just on the basis of symptoms or avoiding UDS. Therefore, in women with POP, especially if scheduled for surgery, UDS should be considered as mandatory, since misleading counselling could result in unpleasant unexpected events.
journal_name
Eur Uroljournal_title
European urologyauthors
Serati M,Salvatore S,Siesto G,Cattoni E,Braga A,Sorice P,Cromi A,Ghezzi F,Bolis Pdoi
10.1016/j.eururo.2011.03.010subject
Has Abstractpub_date
2011-08-01 00:00:00pages
253-60issue
2eissn
0302-2838issn
1873-7560pii
S0302-2838(11)00248-Xjournal_volume
60pub_type
杂志文章相关文献
EUROPEAN UROLOGY文献大全abstract:OBJECTIVES:To assess the opinion amongst the international urological community on whether benign prostatic hyperplasia (BPH) is a progressive disease. METHODS:A 15-item questionnaire was distributed to the mailing list of the publication European Urology Today as well as being accessed through the website of the Euro...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/s0302-2838(02)00065-9
更新日期:2002-05-01 00:00:00
abstract:CONTEXT:Given the highly variable behavior and clinical course of prostate cancer (PCa) and the multiple available treatment options, a personalized approach to oncologic risk stratification is important. Novel genetic approaches offer additional information to improve clinical decision making. OBJECTIVE:To review the...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2015.04.008
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To determine whether preservation of accessory pudendal arteries (APAs) adversely influences the rate of positive surgical margins (PSMs) during laparoscopic radical prostatectomy (LRP). MATERIAL AND METHODS:Between January 2003 and January 2005, 377 men with clinically localized prostate cancer underwent a LR...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2005.08.006
更新日期:2005-11-01 00:00:00
abstract::A prospective randomised study was performed to test the hypothesis that total androgen ablation, achieved by combining an LHRH analogue, goserelin acetate (Zoladex), with an antiandrogen, cyproterone acetate (Cyprostat), is more effective than conventional monotherapy in delaying the time to progression of metastatic...
journal_title:European urology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000473717
更新日期:1996-01-01 00:00:00
abstract:CONTEXT:We addressed the question whether the change of serum prostate-specific antigen (PSA) in men who use 5α-reductase inhibitor (5-ARI) dutasteride is sensitive for the detection of aggressive prostate cancer (PCa). OBJECTIVE:The case of a man using dutasteride diagnosed with Gleason 7 transition zone cancer at bi...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2010.09.035
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To propose a scoring system of difficulties for the most currently performed laparoscopic procedures in urology. MATERIALS AND METHODS:Each current laparoscopic procedure has been evaluated according to three different criteria: technical difficulty, operative risk and the attention required. Each criterion is...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000049742
更新日期:2001-07-01 00:00:00
abstract::In 190 patients with neural tube defects the sensory levels to pin prick were compared with the incidence and distribution of congenital renal anomalies. 17 such anomalies comprised 3 examples of renal agenesis, 5 horseshoe kidneys, 8 ureteral duplications and one simple ureterocele. The pattern of anomalies showed th...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472810
更新日期:1987-01-01 00:00:00
abstract::We have studied embryonic and fetal differentiation of the human prostate in relation to androgen-producing Leydig cell differentiation. We have studied the differentiation of human prostatic glands and the synthesis of acid phosphatase in vivo and in vitro. These studies have shown that the mesenchyme at the level of...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471623
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Energy metabolism is important in cancer proliferation and progression, but its role in prostate cancer (PCa) remains unclear. OBJECTIVE:We explored whether single-nucleotide polymorphisms (SNPs) of genes involved in energy metabolic pathways are associated with PCa risk and prognosis, and whether antidiabe...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2015.03.026
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Extracorporeal shock wave lithotripsy (SWL) treatment of radiolucent ureteric calculi (UC) is hampered by the reduced visibility of the stone. Intravenous contrast medium (IV-CM) administration may overcome this problem by indirectly depicting the localisation of the stone. However, IV-CM administration bears...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000052436
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:Computed tomography (CT) is a commonly used noninvasive procedure for prostate cancer (PCa) staging. All previous studies addressing the ability of CT scan to predict lymph node invasion (LNI) were based on historical patients treated with limited pelvic lymph node dissection (PLND). OBJECTIVE:Assess the va...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2011.11.008
更新日期:2012-06-01 00:00:00
abstract::Urinary incontinence (UI) is a debilitating and embarrassing condition that is prevalent among aging males and females. Little is known about UI in the home hospice setting. We sought to determine UI prevalence and risk factors in a cohort of 15432 home hospice patients over 4yr. Most of the study patients were female...
journal_title:European urology
pub_type: 信件
doi:10.1016/j.eururo.2018.10.027
更新日期:2019-02-01 00:00:00
abstract::Luteinizing hormone-releasing hormone (LH-RH) analogs are an effective treatment of metastatic carcinoma of the prostate. However, they induce an initial rise in serum testosterone responsible for 10-30% of diseases flares. The efficacy of the antiandrogen cyproterone acetate (CPA) was tested in 15 patients with metas...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472667
更新日期:1986-01-01 00:00:00
abstract::A comparative retrospective study was performed on 100 patients who had undergone transurethral resection of a superficial bladder tumor (Ta-Tl) with no associated carcinoma in situ (group 1) and 100 patients who had undergone simultaneous transurethral resection of a superficial bladder tumor (Ta-Tl), with no associa...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473392
更新日期:1988-01-01 00:00:00
abstract::Over a 10-year period 321 children underwent 490 antireflux operations. 21 duplicated vesicoureteric reflux was observed in 18 patients. The follow-up and the comparison with other authors results in 334 patients indicate that the submucosal inlay of the duplicated ureters is a particularly suitable operation. The Pol...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473942
更新日期:1978-01-01 00:00:00
abstract::A case of autohemicastration in a 19-year-old patient with schizophrenia is reported. Orthotopic replantation of the testis under local hypothermia was performed. One pair of arterial, two pairs of venous vessels and vas deferens ends were anastomosed micro-surgically end-to-end. Surgical reinnervation of the testis w...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472797
更新日期:1987-01-01 00:00:00
abstract::We report on the case of a 44-yr-old white man who was referred as an emergency from a local hospital to the medical intensive care unit (ICU) at our institution for progressive multiorgan failure of unknown cause. The CT scan of the abdomen showed a horseshoe kidney with extensive stone formation in both kidneys and ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2007.01.040
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Currently two pretreatment prognostic models with limited accuracy (65-67%) can be used to predict survival in patients with localized renal cell carcinoma (RCC). OBJECTIVE:We set out to develop a more accurate pretreatment model for predicting RCC-specific mortality after nephrectomy for all stages of RCC....
journal_title:European urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.eururo.2008.07.037
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:This paper studies the phenotypical characteristics of the lymphocytes present in mononuclear cell (MNC) preparations from peripheral blood (PBMNC), lymph nodes (LNMNC), tumor bladder (TBMNC), and tumor-free bladder (TFBMNC) from patients with infiltrated transitional cell carcinoma (TCC) of the bladder and ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000474509
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:A disadvantage of prostate-specific antigen (PSA) for the early detection of prostate cancer (PCa) is that many men must be screened, biopsied, and diagnosed to prevent one death. OBJECTIVE:To increase the specificity of screening for lethal PCa at an early stage. DESIGN, SETTING, AND PARTICIPANTS:We condu...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2015.01.009
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Although surgical techniques for radical prostatectomy (RP) have been refined significantly, a significant number of patients still suffer from persisting postprostatectomy stress urinary incontinence (SUI). In recent years, various minimally invasive sling systems have been investigated as treatment options...
journal_title:European urology
pub_type: 临床试验,杂志文章
doi:10.1016/j.eururo.2009.07.028
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Recent large high-quality trials have questioned the clinical effectiveness of medical expulsive therapy using tamsulosin for ureteral stones. OBJECTIVE:To evaluate the efficacy and safety of tamsulosin for distal ureteral stones compared with placebo. DESIGN, SETTING, AND PARTICIPANTS:We conducted a doubl...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2017.10.033
更新日期:2018-03-01 00:00:00
abstract::Ejaculation is constituted by two distinct phases, emission and expulsion. Orgasm, a feature perhaps unique in humans, is a cerebral process that occurs, in normal conditions, concomitantly to expulsion of semen. Normal antegrade ejaculation is a highly coordinated physiological process with emission and expulsion pha...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2005.05.017
更新日期:2005-09-01 00:00:00
abstract::Contralateral biopsies taken from 1,188 patients with testicular germ-cell tumour were examined immunohistologically by staining for placental alkaline phosphatase. Testicular intraepithelial neoplasia (TIN; carcinoma in situ) was detected in 53 patients (4.5%; 95% confidence interval 3.3-5.7%). Testicular atrophy was...
journal_title:European urology
pub_type: 杂志文章,多中心研究
doi:10.1159/000474579
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine the prognostic power of Ki-67 immunostaining in renal cell carcinomas (RCC). METHODS:Clinical follow-up data were reviewed in 111 RCC and the results of Ki-67 immunolabelling were correlated to standard prognostic factors and survival data of the patients. RESULTS:Ki-67...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000474482
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:The aim of our study was to determine the value of duplex Doppler ultrasonography (DDU) in the patients' evolution with renal colic. The study of the resistive index (RI), difference of the RI (ARI) associated with a DDU intravesical recording (ureteral jets) were compared with renographic findings in renal ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/s0302-2838(01)00005-7
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:It is unknown whether lymph node metastases (LNM) and their localization negatively affect clinical outcome in metastatic renal cell carcinoma (mRCC) patients. OBJECTIVE:To evaluate the clinicopathological features, survival outcome, and treatment response in mRCC patients with LNM versus those without LNM ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2014.11.054
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Near-infrared fluorescence (NIRF) imaging is a technology with emerging applications in urologic surgery. OBJECTIVE:To describe surgical techniques and provide clinical outcomes for robotic partial nephrectomy (RPN) with selective clamping and robotic upper urinary tract reconstruction featuring novel appli...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2013.09.023
更新日期:2014-04-01 00:00:00
abstract::We studied 55 renal tissue samples from 16 patients corresponding to normal (19 samples, group 1), low-grade (18 samples, group 2), and high-grade (18 samples, group 3) tumoral tissues. For this purpose, we used digital cell image analysis (the SAMBA 200 processor) to describe the morphonuclear patterns of Feulgen-sta...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473605
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:Investigating whether extracellular factors are possible actors in tumoral progression in bladder carcinoma. METHODS:RT112/G2 bladder tumour cells were grown in presence of TGFbeta and analysed by immunological and cDNA microarray techniques. RESULTS:TGFbeta inhibited cell proliferation, reduced TNFalpha- a...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2005.06.005
更新日期:2005-11-01 00:00:00