Abstract:
OBJECTIVES:To assess the opinion amongst the international urological community on whether benign prostatic hyperplasia (BPH) is a progressive disease. METHODS:A 15-item questionnaire was distributed to the mailing list of the publication European Urology Today as well as being accessed through the website of the European Association of Urology (EAU). The survey included questions on: whether BPH was a progressive disorder; what evidence there was to support this, including clinical parameters that could be identified; risk factors for progression; and prevention of progression. RESULTS:A total of 472 completed questionnaires from 47 countries were evaluated. Overall, the urologists surveyed agreed that BPH was a progressive disease, and that some patients were more prone to this than others. Increased post-void residual urine, reduced flow rate, increased urinary symptoms and urodynamic evidence of obstruction were considered to be the most significant risk factors for progression. Half of the urologists surveyed considered that current medical therapies could prevent progression of BPH, while a significant proportion thought that surgery was an effective preventative measure. CONCLUSIONS:BPH, although a benign disease, has a considerable impact on the patient's quality of life. Its progressive nature and the identification of risk factors for progression warrant further investigation. In the future, there is likely to be a shift in the paradigm from treatment of BPH complications to include the prevention of BPH progression.
journal_name
Eur Uroljournal_title
European urologyauthors
Djavan B,Nickel JC,de la Rosette J,Abrams Pdoi
10.1016/s0302-2838(02)00065-9keywords:
subject
Has Abstractpub_date
2002-05-01 00:00:00pages
490-6issue
5eissn
0302-2838issn
1873-7560pii
S0302283802000659journal_volume
41pub_type
杂志文章相关文献
EUROPEAN UROLOGY文献大全abstract::Nine patients, mean age 55 years, with testicular hydroceles, were treated by aspiration and two-component fibrin glue injection. One patient was treated twice. The glue contains 70-110 mg fibrinogen and 500 IU human thrombin in 0.5- and 2-ml injections, respectively (Tisseel duo quick, Immune AB). The smaller glue vo...
journal_title:European urology
pub_type: 临床试验,杂志文章
doi:10.1159/000019641
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:With current treatments, men usually survive many years after being diagnosed with prostate cancer. However, without supportive care, the systemic effects of prostate cancer and therapies such as androgen deprivation therapy (ADT) can undermine skeletal integrity, resulting in skeletal complications that may ...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2004.08.016
更新日期:2004-12-01 00:00:00
abstract::The three diffuse projection systems arising in the brainstem, that is, noradrenergic projection originating in the locus coeruleus, serotonergic projection from the dorsal raphe nucleus, and cholinergic projection from neurons gathering in the laterodorsal tegmental nucleus and scattering in the pedunculopontine tegm...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000052235
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To evaluate the impact of androgen deprivation on health related quality of life (HRQOL) in patients with asymptomatic lymph node positive prostatic carcinoma (LPPC). MATERIALS AND METHODS:HRQOL domains were measured, using standard instruments in 91 patients with histologically proven LPPC. Most patients were...
journal_title:European urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0302-2838(03)00208-2
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the relative accuracy of a computerised method to quantitatively assess maximum urinary flow. METHODS:A total of 1147 uroflows were evaluated by the computerised method and by three experts from different European countries. The sample consisted of uroflows from the respective visits by a 20% sa...
journal_title:European urology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0302-2838(01)00037-9
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Laparoscopic cryoablation (LCA) and percutaneous cryoablation (PCA) of small renal masses have gained popularity, but only limited data exist on the complication rates. OBJECTIVES:In this study, we report on postoperative complications associated with LCA and PCA in a single tertiary center experience. DES...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2010.03.035
更新日期:2010-07-01 00:00:00
abstract::With the introduction of laparoscopy into adult urology, a vast new field has suddenly opened itself up to the urologic surgeon, filled with exciting and promising possibilities of applying the principles of minimally invasive surgery to an ever increasing number of diseases that so far have only been approachable by ...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000475237
更新日期:1994-01-01 00:00:00
abstract::Histomorphometric measurements of tumour-free bone have been undertaken in a closely matched group of patients with metastatic prostate cancer treated either by subcapsular orchidectomy (SCO) or luteinising hormone-releasing hormone (LHRH) agonists. Age, fasting morning urine hydroxyproline/creatinine ratios, alkaline...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473597
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:To review the role of postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) in patients with advanced testicular germ cell tumours (TGCT) with special attention towards the indication, surgical technique, and oncological outcome. METHODS:A structured review of the literature until May 2007 using...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2007.10.033
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:Prostate cancer is a leading cause of cancer-related mortality and morbidity in Western world. Curative treatment is feasible provided the disease is diagnosed in its earliest stages, but current screening methodologies are characterized by low specificity. DNA-based markers are a class of new and promising t...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2004.06.014
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:The authors present demographic and surgical data from a randomized phase III trial, instituted by the EORTC Genitourinary Group in 1988, the aim of which was to assess whether complete lymph node dissection in conjunction with radical nephrectomy for renal cell cancer is more effective than radical nephrecto...
journal_title:European urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000020050
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVES:Our technique of laparoscopic adrenalectomy as well as the results of this method are presented. METHODS:Transperitoneal laparoscopic adrenalectomy was performed in 18 consecutive patients (10 right side, 8 left side) for Conn's disease (7 patients), pheochromocytoma (6 patients), Cushing's syndrome (1 pati...
journal_title:European urology
pub_type: 临床试验,杂志文章
doi:10.1159/000474218
更新日期:1996-01-01 00:00:00
abstract::A case of nonoperative renal stone extraction through a nephrostomy tract is described. The stone was removed with the aid of a newly constructed device. The advantage of this device over a Dormia stone basket is that it has a steerable tip, which facilitates trapping of the stone in the basket. ...
journal_title:European urology
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The descriptive epidemiology of testicular cancer in Denmark shows that the incidence of both seminoma and non-seminoma has increased gradually since the 1940s to the present. The age-incidence pattern has remained unchanged, and is the same in the Nordic countries despite variation in the overall incidence level. Men...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000474564
更新日期:1993-01-01 00:00:00
abstract::The chemical analysis of the fluid obtained by puncturing 100 simple renal cysts in adults show that the composition of cystic fluid resembles that of interstitial fluid. The chemical balance between cystic fluid and the interstitial space seems to occur passively. Antibiotics which were given orally (amoxycilline, mi...
journal_title:European urology
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::A double-blind trial was conducted in 138 patients with superficial transitional cell carcinoma of the bladder following transurethral resection to evaluate the prophylaxis of recurrence by an oral Lactobacillus casei preparation (BLP). Patients were stratified into the following 3 subgroups: (A) with primary multiple...
journal_title:European urology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000475138
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Incontinence has a greater detrimental effect on quality of life than other symptoms of overactive bladder (OAB) and is often difficult to treat with antimuscarinic monotherapy. OBJECTIVE:To evaluate the efficacy and the safety and tolerability of combination (solifenacin 5mg and mirabegron 50mg) versus sol...
journal_title:European urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.eururo.2016.02.030
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the long-term results of the transvaginal needle suspension operation for urinary stress incontinence. MATERIALS AND METHODS:A total of 88 women with proved genuine stress incontinence were treated with transvaginal needle suspension with fixation of suspension sutures to the rectus fascia using...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000052364
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVES:To perform a prospective, placebo-controlled study to examine the efficacy of alpha-blocker compared with triple therapy (alpha-blocker, anti-inflammatory, and muscle relaxant) in the treatment of Category IIIB chronic pelvic pain syndrome (Category IIIB CPPS). MATERIALS AND METHODS:The study was conducted ...
journal_title:European urology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.eururo.2006.09.036
更新日期:2007-04-01 00:00:00
abstract::We report on the case of a 44-yr-old white man who was referred as an emergency from a local hospital to the medical intensive care unit (ICU) at our institution for progressive multiorgan failure of unknown cause. The CT scan of the abdomen showed a horseshoe kidney with extensive stone formation in both kidneys and ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2007.01.040
更新日期:2007-12-01 00:00:00
abstract::In a group of 17 patients of postpubertal age with unilateral (n = 15) or bilateral (n = 2) cryptorchism, a significant decrease in the tubular diameter was observed, in addition to Leydig cell hyperplasia (many with cytoplasm vacuolization and/or atrophy) in both the cryptorchid testes and in the contralateral scrota...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471635
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Patients with urgency urinary incontinence (UUI) due to overactive bladder (OAB) refractory to oral antimuscarinics have limited therapeutic options. OnabotulinumtoxinA appears to be an effective new treatment. OBJECTIVE:Assess disease-specific quality-of-life outcomes and general health-related quality-of-...
journal_title:European urology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.eururo.2012.03.005
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVES:Pelvic lymph node metastases indicate a poor prognosis for patients with clinically localized prostate cancer. The aim of the study was to investigate the value of extended histopathological techniques considering the extent of pelvic lymphadenectomy and preoperative risk factors. METHODS:Total of 194 patie...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/s0302-2838(02)00450-5
更新日期:2003-02-01 00:00:00
abstract:PURPOSE:In industrialized countries the prevalence of upper urinary tract stones has continually increased during the 20th century, but there are considerable differences between countries and also within the same country. To study whether there is still an increase in the frequency of renal stones, an investigation wa...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000020094
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To investigate prognostic factors in localized and lymphatically spread prostate cancer. METHODS:The biochemical course after radical retropubic prostatectomy in 306 patients was subject to a retrospective analysis. RESULTS:Prostate-specific antigen (PSA), Gleason score (prostatectomy specimen) and patholog...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000052479
更新日期:2001-04-01 00:00:00
abstract::We report on 18 patients, aged 43-77 years, with clinical stage-C adenocarcinoma of the prostate, primarily treated by pelvic lymphadenectomy and 125I-seed implantation. After lymphadenectomy, the staging assessment differed from the preoperative diagnosis as follows: 4 patients were classified as stage C; 6 as D1, an...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472587
更新日期:1986-01-01 00:00:00
abstract::We report 5 cases of severe Peyronie's disease treated by a new procedure. It consists of making parallel I-shaped incisions on the dorsal face of the penis so that the shortened part of the albuginea can increase. The 2 defects are covered with 2 patches of dura mater. All the cases except one had good results, eithe...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471640
更新日期:1989-01-01 00:00:00
abstract::Alpha1-adrenoceptor antagonists have been shown to decrease both the voiding and storage symptoms of benign prostatic hyperplasia (BPH). Based on the assumption that these symptoms can be attributed to the consequences of the increase in outflow resistance caused by noradrenaline stimulation of stromal alpha1-adrenoce...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000052228
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:We present a multicenter, population-based epidemiological survey aimed at assessing the prevalence of Peyronie's disease (PD) and its potential risk factors in the general population. METHODS:In each of the ten centers throughout Italy, a uroandrologist contacted all the men in the age range 50-69 years re...
journal_title:European urology
pub_type: 杂志文章,多中心研究
doi:10.1159/000049830
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Anandamide, a proposed endogenous cannabinoid (CB) agonist, has been shown to enhance neurogenic responses in vitro of the rat corpus cavernosal tissue (CC). However, no information is available on the distribution of CB-receptors or effects by anandamide in CC from primates or humans. OBJECTIVE:To characte...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2008.12.024
更新日期:2010-02-01 00:00:00