Basal ganglia volume and clinical correlates in 'preclinical' Huntington's disease.

abstract：:Horizontal eye-movement responses of four patients with Alzheimer-type dementia were recorded using the infrared oculographic technique. Abnormally frequent saccadic intrusions occurred during the fixation and slow, smooth pursuit tasks in all four patients. Saccadic intrusions have previously been reported in the lit...

journal_title：Journal of neurology

authors： Jones A,Friedland RP,Koss B,Stark L,Thompkins-Ober BA

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The aim of study was to demonstrate that the first three injections of botulinum neurotoxin type A (BoNT/A) appear to be less effective in botulinum toxin naïve patients with idiopathic cervical dystonia (CD) with mild symptoms and low severity scores (TSUI-scores) at onset of BoNT/A-therapy compared to pati...

journal_title：Journal of neurology

authors： Hefter H,Samadzazeh S,Rosenthal D

更新日期：2021-01-01 00:00:00

abstract：:Levamisole seems to regulate cell-mediated immunity by restoring T-cell function. Since a deficiency of T lymphocytes has been described by various authors in multiple sclerosis patients. Of the 85 patients involved in the trial, evaluation of functional and neurological scores was possible in 54 (32 with placebo and ...

journal_title：Journal of neurology

authors： Gonsette RE,Demonty L,Delmotte P,Decree J,de Cock W,Verhaeghen H,Symoens J

更新日期：1982-01-01 00:00:00

abstract：:Biomarkers beyond clinical assessment are needed in patients who suffer from amyotrophic lateral sclerosis (ALS). Here, single-voxel proton magnetic resonance spectroscopy ((1)H MRS) of the gray matter of the motor cortex and the white matter including the pyramidal tracts was used to investigate concentrations of N-a...

journal_title：Journal of neurology

authors： Unrath A,Ludolph AC,Kassubek J

更新日期：2007-08-01 00:00:00

abstract：:Neurological complications in the acquired immunodeficiency syndrome (AIDS) are an important aspect of this new infectious disease and occur frequently. The existence of neurotropic variants of the human immunodeficiency virus (HIV), the causative agent of AIDS, is probable. Direct infection of the nervous system with...

journal_title：Journal of neurology

authors： Fischer PA,Enzensberger W

更新日期：1987-06-01 00:00:00

abstract：:Knowledge of restless legs syndrome (RLS) has greatly increased in recent years due to the many advances that have been made in diagnosis, management and genetics. Tools have been developed that facilitate the diagnosis and treatment of RLS, in particular the essential diagnostic criteria for RLS have been refined, se...

journal_title：Journal of neurology

authors： Trenkwalder C,Högl B,Winkelmann J

更新日期：2009-04-01 00:00:00

abstract：:Magnetisation transfer (MT) imaging provides indirect information on tissue structure abnormalities in areas that otherwise may appear normal on conventional MRI. We determined the evolution of MT changes in normal appearing white matter (NAWM) and lesion on serial examination of 9 multiple sclerosis (MS) patients and...

journal_title：Journal of neurology

authors： Laule C,Vavasour IM,Whittall KP,Oger J,Paty DW,Li DK,MacKay AL,Arnold DL

更新日期：2003-08-01 00:00:00

abstract：:We report the case of a 17.5-year old girl with generalized myasthenia gravis (MG). When she was 13, she started to complain of episodic diplopia, ptosis and mild fatigability of upper and lower extremity muscles. She was diagnosed with MG 3 years later, after exacerbation of her limb muscle weakness. Acetylcholine re...

journal_title：Journal of neurology

authors： Kostera-Pruszczyk A,Kwiecinski H

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Single, modifiable risk factors for stroke have extensively been studied. In contrast, differences of their combined effects among stroke and transitoy ischemic attack (TIA) have been rarely investigated. The aim of the present study was to assess single and joint effects of risk factors on the incidence of ...

journal_title：Journal of neurology

authors： Weikert C,Berger K,Heidemann C,Bergmann MM,Hoffmann K,Klipstein-Grobusch K,Boeing H

更新日期：2007-03-01 00:00:00

abstract：:Recent reports suggest the possible beneficial effects of haemopoietic stem cell transplantation (HSCT) in autoimmune diseases such as multiple sclerosis (MS). The definition of the risk/benefit ratio for such a treatment is perceived as a major issue for the neurological community worldwide. The First Consensus Confe...

journal_title：Journal of neurology

authors： Comi G,Kappos L,Clanet M,Ebers G,Fassas A,Fazekas F,Filippi M,Hartung HP,Hertenstein B,Karussis D,Martino G,Tyndall A,van der Meché FG

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Classifying and diagnosing peripheral vestibular disorders based on their symptoms is challenging due to possible symptom overlap or atypical clinical presentation. To improve the diagnostic trajectory, gadolinium-based contrast-enhanced magnetic resonance imaging of the inner ear is nowadays frequently used...

journal_title：Journal of neurology

authors： van der Lubbe MFJA,Vaidyanathan A,Van Rompaey V,Postma AA,Bruintjes TD,Kimenai DM,Lambin P,van Hoof M,van de Berg R

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Duchenne muscular dystrophy (DMD) is induced by a wide spectrum of mutations such as exon deletions, duplications and small mutations in the dystrophin gene. This is the first study on the mutational spectrum in a cohort of DMD children from India, with an emphasis to compare the mutations in familial and ...

journal_title：Journal of neurology

authors： Polavarapu K,Preethish-Kumar V,Sekar D,Vengalil S,Nashi S,Mahajan NP,Thomas PT,Sadasivan A,Warrier M,Gupta A,Arunachal G,Debnath M,Keerthipriya MS,Pradeep-Chandra-Reddy C,Puttegowda A,John AP,Tavvala A,Gunasekaran S,S

更新日期：2019-09-01 00:00:00

abstract：:Secondary worsening of stroke symptoms is described in 13-37% of stroke patients, but the exact mechanism of this phenomenon remains unclear. The aim of this study is to find prognostic variables in correlation to secondary worsening of stroke symptoms in patients with lacunar or cortical strokes. In this prospective ...

journal_title：Journal of neurology

authors： Schweitzer JR,Koehler PJ,Voogd AC,Franke CL

更新日期：2010-09-01 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurological disorder characterized by motor symptoms as well as severe deficits in olfactory function and microstructural changes in olfactory brain regions. Because of the evidence of asymmetric neuropathological features in early-stage PD, we examined whether lateralized mi...

journal_title：Journal of neurology

authors： Joshi N,Rolheiser TM,Fisk JD,McKelvey JR,Schoffer K,Phillips G,Armstrong M,Khan MN,Leslie RA,Rusak B,Robertson HA,Good KP

更新日期：2017-07-01 00:00:00

abstract：:Homozygous mutations in the PINK1 gene have been shown to cause early-onset parkinsonism. Here, we describe a novel homozygous mutation (Q126P), identified in two affected German sisters with a clinical phenotype typical for PINK1-associated parkinsonism. We analysed lactate, pyruvate, carnitine and acylcarnitine bloo...

journal_title：Journal of neurology

authors： Prestel J,Gempel K,Hauser TK,Schweitzer K,Prokisch H,Ahting U,Freudenstein D,Bueltmann E,Naegele T,Berg D,Klopstock T,Gasser T

更新日期：2008-05-01 00:00:00

abstract：:Using high-performance liquid chromatography, adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN) were diagnosed by the analysis of fatty acids in sphingomyelin. The analytical method was simple, sensitive and accurate. In ALD and AMN patients, very long chain fatty acids (C26:0, C25:0 and C24:0 on the base of ...

journal_title：Journal of neurology

authors： Kobayashi T,Katayama M,Suzuki S,Tomoda H,Goto I,Kuroiwa Y

更新日期：1983-01-01 00:00:00

abstract：:Headache attributed to ingestion of a cold stimulus (ICHD-3 beta 4.5.1) is also known as ice cream headache (ICH). This cross-sectional epidemiological study included 283 students (10-14-year-olds) attending a grammar school in Germany, their parents (n = 401), and 41 teachers. A self-administered questionnaire was us...

journal_title：Journal of neurology

authors： Zierz AM,Mehl T,Kraya T,Wienke A,Zierz S

更新日期：2016-06-01 00:00:00

abstract：:There is increasing evidence that inflammation plays an important role in the progression of acute ischemic stroke (AIS). The primary aims of this study were to examine the serum levels of 13 cytokines, C-reactive protein (CRP), glucose, and hemoglobin in AIS patients, and their relationship to stroke lateralization, ...

journal_title：Journal of neurology

authors： Ormstad H,Aass HC,Lund-Sørensen N,Amthor KF,Sandvik L

更新日期：2011-04-01 00:00:00

abstract：:Functional changes in the organisation of neuronal circuitries are generally used to explain parkinsonian motor symptoms and levodopa-induced dyskinesias. Based on information from histology and neurophysiological microrecordings of specific basal ganglia nuclei, the most widely accepted scheme is based on a central l...

journal_title：Journal of neurology

authors： Delwaide PJ,Pepin JL,De Pasqua V,de Noordhout AM

更新日期：2000-04-01 00:00:00

abstract：:In order to learn more on the occurrence of pains and motor deficit in severe diabetic polyneuropathy we reviewed the data of a series of 30 diabetic patients with an uncommonly severe length-dependent diabetic polyneuropathy (LDDP). Extensive sensory loss predominated with pains and temperature sensations and affecte...

journal_title：Journal of neurology

authors： Said G,Baudoin D,Toyooka K

更新日期：2008-11-01 00:00:00

abstract：:Two right-handed patients who exhibited language disability after left frontal infarction are described. The patients spoke fluently and exhibited excellent repetition ability from the onset of infarction without exhibiting any oral apraxia, but had deficits in auditory comprehension, naming, reading and writing. In b...

journal_title：Journal of neurology

authors： Otsuki M,Soma Y,Koyama A,Yoshimura N,Furukawa H,Tsuji S

更新日期：1998-02-01 00:00:00

abstract：:There have been few reports concerning the characteristics of cerebral infarction associated with migraine (CIAM), and especially about the subsequent fate of these patients. We studied 14 patients (9 female) with CIAM. In all these patients the onset of cerebral infarction was accompanied by a unilateral throbbing he...

journal_title：Journal of neurology

authors： Hoekstra-van Dalen RA,Cillessen JP,Kappelle LJ,van Gijn J

更新日期：1996-07-01 00:00:00

abstract：:Recent genetic studies suggest a Sardinian type of amyotrophic lateral sclerosis (ALS). Thus, ALS incidence, prevalence and survival were investigated in a large population of Sardinians aimed to disclose population-specific patterns and their temporal changes. This is a population-based incidence and prevalence study...

journal_title：Journal of neurology

authors： Pugliatti M,Parish LD,Cossu P,Leoni S,Ticca A,Saddi MV,Ortu E,Traccis S,Borghero G,Puddu R,Chiò A,Pirina P

更新日期：2013-02-01 00:00:00

abstract：:In the epidemiological area of Southern Lower Saxony 92 patients with clinically definite or probable diagnosis of multiple sclerosis (MS) were interviewed and examined. This group contained a remarkably high percentage of benign cases (52%) in comparison with a sample of hospitalized patients. Neurological examinatio...

journal_title：Journal of neurology

authors： Poser S,Bauer HJ,Ritter G,Friedrich H,Beland H,Denecke P

更新日期：1981-01-01 00:00:00

abstract：:The effect of local cooling was studied in 28 patients with myastenia gravis. We stimulated the ulnar nerve with single stimuli and trains at 3/s for 2s and at 50/s for 1.5 s. The compound muscle action potential (MAP), the muscle twitch and the isometric tetanic force of the adductor pollicis were registered. 1. At 3...

journal_title：Journal of neurology

authors： Ricker K,Hertel G,Stodieck S

更新日期：1977-11-01 00:00:00

abstract：:The International Cooperative Ataxia Rating Scale (ICARS) is a 100-point semiquantitative scale designed primarily to assess cerebellar dysfunction. However, little is known of the metric properties of this scale. We assessed the ICARS by rating the severity of cerebellar dysfunction in 27 patients with spinocerebella...

journal_title：Journal of neurology

authors： Wang PS,Liu RS,Yang BH,Soong BW

更新日期：2007-06-01 00:00:00

abstract：:Nystagmus is a rhythmical rotation of the eyeball. Its characteristics can be defined mathematically by the axis of rotation and the angular velocity around this axis. We analysed the axis of rotation for the nystagmus in benign paroxysmal positional vertigo (BPPV) to elucidate its pathophysiology. Thirteen patients w...

journal_title：Journal of neurology

authors： Hayashi Y,Kanzaki J,Etoh N,Higashino K,Goto F,Schneider E,Kunihiro T

更新日期：2002-12-01 00:00:00

abstract：:An 18-year-old man suffered from acute Sydenham chorea appearing coincidently with beta-haemolytic streptococcal throat infection. Imaging techniques documented lesions of basal ganglia and substantia nigra. In the early course of the disease vascular lesions may be important pathogenetic mechanisms of this acquired m...

journal_title：Journal of neurology

authors： Heye N,Jergas M,Hötzinger H,Farahati J,Pöhlau D,Przuntek H

更新日期：1993-02-01 00:00:00

abstract：:We describe three patients in whom an isolated sixth nerve palsy was the only clinical symptom or sign of multiple sclerosis (MS). Data were collected prospectively over 6 years on these three patients, who showed no other signs of brainstem dysfunction or prior symptoms; in addition. Retrospective analysis of all pat...

journal_title：Journal of neurology

authors： Barr D,Kupersmith MJ,Turbin R,Bose S,Roth R

更新日期：2000-09-01 00:00:00

abstract：:Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among UK participants, what clinical and psycho-social characteristics are associated with QoL. ...

journal_title：Journal of neurology

authors： Ridsdale L,Wojewodka G,Robinson E,Landau S,Noble A,Taylor S,Richardson M,Baker G,Goldstein LH,SMILE Team.

更新日期：2017-06-01 00:00:00