Dopamine D2 receptor binding and cerebral glucose metabolism recover after D-penicillamine-therapy in Wilson's disease.

abstract：:Infectious agents have been proposed as potential causes of Alzheimer's disease (AD). Recently, we documented a high prevalence of Helicobacter pylori (Hp) infection in patients with AD. We aim to access the effect of Hp eradication on the AD cognitive (MMSE: Mini Mental State Examination and CAMCOG: Cambridge Cogniti...

journal_title：Journal of neurology

authors： Kountouras J,Boziki M,Gavalas E,Zavos C,Grigoriadis N,Deretzi G,Tzilves D,Katsinelos P,Tsolaki M,Chatzopoulos D,Venizelos I

更新日期：2009-05-01 00:00:00

abstract：:We investigated the effect of chronic mechanical compression of the cervical spinal cord on the number of spinal accessory motoneurons in 25 tiptoe-walking Yoshimura mice. The animals had calcified deposits in the atlantoaxial membrane at the C1-C2 vertebral level, compressing the spinal cord posterolaterally. Motoneu...

journal_title：Journal of neurology

authors： Baba H,Maezawa Y,Uchida K,Imura S,Kawahara N,Tomita K,Kudo M

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence and risk factors for paroxysmal atrial fibrillation (PAF) diagnosis in non- cryptogenic ischemic stroke (CIS) patients. METHODS:In this pilot-prospective cohort study of non-CIS patients from September 2014 to September 2017, 53 patients were enrolled. 51/53 patients were implante...

journal_title：Journal of neurology

authors： Katz JM,Eng MS,Carrazco C,Patel AV,Jadonath R,Gribko M,Arora R,Libman RB

更新日期：2018-10-01 00:00:00

abstract：:The follow-up of neurophysiological tests (brain-stem auditory evoked potentials; blink reflex; sensory, motor and visual evoked potentials) and CT was investigated in 21 patients with late-onset cerebellar ataxia (CA) or multiple system atrophy. The study included an initial investigation and a follow-up examination ...

journal_title：Journal of neurology

authors： Wessel K,Huss GP,Brückmann H,Kömpf D

更新日期：1993-01-01 00:00:00

abstract：:The experience of music is difficult to study objectively. Here we describe a detailed analysis of musical hallucinations developing after a probable brainstem stroke in an 83 year old musician who was able to describe and notate the hallucinations. The hallucinations comprised simple, repetitive melodic and rhythmic ...

journal_title：Journal of neurology

authors： Warren JD,Schott GD

更新日期：2006-08-01 00:00:00

abstract：:We describe three patients with a late presentation of congenital muscular torticollis to emphasize that this non-dystonic type of torticollis has to be considered in the differential diagnosis of cervical dystonia, even in adult patients. Surgery is the treatment of choice. Postoperatively, two of our patients had a ...

journal_title：Journal of neurology

authors： Brans J,Aramideh M,Bosch A,Speelman H

更新日期：1996-04-01 00:00:00

abstract：:Applying microarray technology to identify new diagnostic and prognostic markers in peripheral blood cells (PBC) after therapeutic intervention opens great perspectives regarding patient subclassification. Three recombinant products of the pleiotropic agent interferon beta (rIFN-beta) are available for disease modifyi...

journal_title：Journal of neurology

authors： Goertsches RH,Hecker M,Zettl UK

更新日期：2008-12-01 00:00:00

abstract：:Cerebellar dysfunction is an important contributor to disability in patients with multiple sclerosis (MS), however, few in vivo studies focused on cerebellar volume loss so far. This relates to technical challenges regarding the segmentation of the cerebellum. In this study, we evaluated the semi-automatic ECCET softw...

journal_title：Journal of neurology

authors： Weier K,Beck A,Magon S,Amann M,Naegelin Y,Penner IK,Thürling M,Aurich V,Derfuss T,Radue EW,Stippich C,Kappos L,Timmann D,Sprenger T

更新日期：2012-12-01 00:00:00

abstract：:Various ancillary investigations can assist clinicians in the differential diagnosis of patients with parkinsonism. It is unknown which test offers greatest diagnostic value in clinical practice. We included 156 consecutive patients with parkinsonism, but with an initially uncertain diagnosis. At baseline, all patient...

journal_title：Journal of neurology

authors： Aerts MB,Esselink RA,Abdo WF,Meijer FJ,Drost G,Norgren N,Janssen MJ,Borm GF,Bloem BR,Verbeek MM

更新日期：2015-02-01 00:00:00

abstract：:Recent genetic studies suggest a Sardinian type of amyotrophic lateral sclerosis (ALS). Thus, ALS incidence, prevalence and survival were investigated in a large population of Sardinians aimed to disclose population-specific patterns and their temporal changes. This is a population-based incidence and prevalence study...

journal_title：Journal of neurology

authors： Pugliatti M,Parish LD,Cossu P,Leoni S,Ticca A,Saddi MV,Ortu E,Traccis S,Borghero G,Puddu R,Chiò A,Pirina P

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To report the clinical features and long-term outcome of 22 newly diagnosed paraneoplastic patients with GABAB receptor antibodies (GABABR-Abs). METHODS:Retrospective clinical study of CSF-confirmed cases of GABABR-Abs encephalitis. RESULTS:We identified 22 patients (4 female) with GABABR-Abs, with a median...

journal_title：Journal of neurology

authors： Maureille A,Fenouil T,Joubert B,Picard G,Rogemond V,Pinto AL,Thomas L,Ducray F,Quadrio I,Psimaras D,Berzero G,Antoine JC,Desestret V,Honnorat J

更新日期：2019-01-01 00:00:00

abstract：:The number of dementia patients requesting euthanasia in the Netherlands has increased over the past five years. The issue is highly controversial. In this contribution we discuss some of the main arguments: the nature of suffering, the voluntariness of the request and the role of the physician. We argue that society ...

journal_title：Journal of neurology

authors： de Beaufort ID,van de Vathorst S

更新日期：2016-07-01 00:00:00

abstract：:Postpartum lower limb motor and/or sensory deficit is an uncommon obstetrical complication. We aimed to identify its incidence, etiology, and precipitating factors, as well as the neurological prognosis by retrospectively analyzing the successive neurological evaluations, electrophysiological, and MRI data from all th...

journal_title：Journal of neurology

authors： Richard A,Vellieux G,Abbou S,Benifla JL,Lozeron P,Kubis N

更新日期：2017-03-01 00:00:00

abstract：:The cases of identical twins with ataxia telangiectasia, early intellectual impairment and progressive spasticity are reported. Immunological tests revealed reduced levels of serum and salivary IgA, increased B cells, reduced T cells and raised alpha-fetoprotein. CT scan performed in one of the twins was normal. The p...

journal_title：Journal of neurology

authors： Meshram CM,Sawhney IM,Prabhakar S,Chopra JS

更新日期：1986-10-01 00:00:00

abstract：:Elevated uric acid levels have recently been found to be associated with slower disease progression in Parkinson's disease, Huntington's disease, multiple system atrophy, and mild cognitive impairment. The aim of this study is to determine whether serum uric acid levels predict survival in amyotrophic lateral sclerosi...

journal_title：Journal of neurology

authors： Paganoni S,Zhang M,Quiroz Zárate A,Jaffa M,Yu H,Cudkowicz ME,Wills AM

更新日期：2012-09-01 00:00:00

abstract：UNLABELLED:To systematically and comprehensively describe functioning and disability in Multiple sclerosis (MS), practical tools based on the International Classification of Functioning, Disability and Health (ICF), such as ICF Core Sets, are needed. OBJECTIVE:To report on the results of an evidence-based Internationa...

journal_title：Journal of neurology

authors： Coenen M,Cieza A,Freeman J,Khan F,Miller D,Weise A,Kesselring J,Members of the Consensus Conference.

更新日期：2011-08-01 00:00:00

abstract：:We investigated the efficacy of botulinum toxin A (BtxA) therapy in patients with atypical parkinsonian disorders (APD) exhibiting different types of disabling focal dystonia unresponsive to oral drug therapy. Eight patients with functionally disabling focal dystonia out of a series of 60 consecutive patients with APD...

journal_title：Journal of neurology

authors： Müller J,Wenning GK,Wissel J,Seppi K,Poewe W

更新日期：2002-03-01 00:00:00

abstract：:Interferon beta (IFNbeta) therapy for multiple sclerosis (MS) is associated with a potential for the development of neutralising antibodies (NAbs) that negatively affect therapy. Several factors influence the development of NAbs, such as lack of complete sequence homology with the endogenous IFNbeta sequence, frequenc...

journal_title：Journal of neurology

authors： Hartung HP,Polman C,Bertolotto A,Deisenhammer F,Giovannoni G,Havrdova E,Hemmer B,Hillert J,Kappos L,Kieseier B,Killestein J,Malcus C,Comabella M,Pachner A,Schellekens H,Sellebjerg F,Selmaj K,Sorensen PS

更新日期：2007-07-01 00:00:00

abstract：:A 15-year-old boy with Tourette's syndrome exhibited severe involuntary self-mutilatory behavior. While clonidine effectively controlled the motor and phonic tics, it failed to ameliorate the self-mutilatory behavior. Administration of oxycodone (50 mg/day) combined with clonidine produced a dramatic reduction in the ...

journal_title：Journal of neurology

authors： Sandyk R

更新日期：1986-06-01 00:00:00

abstract：AIM:To assess: (1) the prevalence of convexity subarachnoid hemorrhage (cSAH) in infective endocarditis (IE); (2) its relationship with IE features; (3) the associated lesions; (4) whether cSAH is a predictor of future hemorrhage; (5) whether cSAH could cause cortical superficial siderosis (cSS). METHODS:We retrospect...

journal_title：Journal of neurology

authors： Boukobza M,Ilic-Habensus E,Duval X,Laissy JP

更新日期：2020-10-01 00:00:00

abstract：:The aims of this study are to investigate whether auditory dysfunction is part of the spectrum of neurological abnormalities associated with Leber's hereditary optic neuropathy (LHON) and to determine the perceptual consequences of auditory neuropathy (AN) in affected listeners. Forty-eight subjects confirmed by genet...

journal_title：Journal of neurology

authors： Rance G,Kearns LS,Tan J,Gravina A,Rosenfeld L,Henley L,Carew P,Graydon K,O'Hare F,Mackey DA

更新日期：2012-03-01 00:00:00

abstract：:We investigated the visual event-related potentials (ERPs) in two subtypes of multisystem atrophy (MSA) in 15 MSA-C patients, 12 MSA-P patients, and 21 normal control (NC) subjects. We used a visual oddball task to elicit ERPs. No significant changes were seen in N1 or N2 latency, in either MSA-C or MSA-P, compared wi...

journal_title：Journal of neurology

authors： Kamitani T,Kuroiwa Y,Wang L,Li M,Suzuki Y,Takahashi T,Ikegami T,Matsubara S

更新日期：2002-08-01 00:00:00

abstract：:This study aimed at an analysis of the release of Braintype and Heart-type Fatty Acid- Binding Proteins (B-FABP and HFABP) in acute ischaemic stroke and their potential value as neurobiochemical markers of brain damage. We investigated 42 consecutive patients admitted within 6 hours after ischaemic stroke. Serial veno...

journal_title：Journal of neurology

authors： Wunderlich MT,Hanhoff T,Goertler M,Spener F,Glatz JF,Wallesch CW,Pelsers MM

更新日期：2005-06-01 00:00:00

abstract：:Long-term treatment studies with any antiparkinsonian drug are rather limited. Especially, double-blind, randomized and multicenter studies do not exist except for some rare exceptions. Nonetheless, such studies are mandatory to prove certain therapy regimens. This overview reports on the comparison between dopamine a...

journal_title：Journal of neurology

authors： Reichmann H

更新日期：2000-09-01 00:00:00

abstract：:Spinocerebellar ataxias (SCA) are a genetically heterogeneous group of neurodegenerative diseases characterised by progressive cerebellar ataxia, dysarthria and oculomotor abnormalities. Recently the prodynorphin (PDYN) gene was identified as the cause of SCA23 in four Dutch families displaying progressive gait and li...

journal_title：Journal of neurology

authors： Fawcett K,Mehrabian M,Liu YT,Hamed S,Elahi E,Revesz T,Koutsis G,Herscheson J,Schottlaender L,Wardle M,Morrison PJ,Morris HR,Giunti P,Wood N,Houlden H

更新日期：2013-03-01 00:00:00

abstract：:Several viruses have the capacity to cause serious infections of the nervous system in patients who are immunosuppressed. Individuals may be immunosuppressed because of primary inherited immunodeficiency, secondary immunodeficiency due to particular diseases such as malignancy, administration of immunosuppressant drug...

journal_title：Journal of neurology

authors： Kennedy PGE

更新日期：2020-10-13 00:00:00

abstract：:Raised intracranial pressure in association with spinal meningeal cysts has rarely been reported. We describe four patients in whom evidence of paroxysmal raised intracranial pressure was found in association with spinal meningeal cysts. Cerebrospinal fluid diversion procedures have previously been shown to relieve lo...

journal_title：Journal of neurology

authors： Shams PN,Goadsby PJ,Crockard HA,Casey AT,Plant GT

更新日期：2005-03-01 00:00:00

abstract：:Twenty-four patients with unilateral facial weakness of various aetiologies were investigated using a magnetic stimulator to stimulate the proximal segment of the facial nerve directly (short latency response) and also to activate the facial motoneurons bilaterally via corticonuclear pathways by placing the stimulatin...

journal_title：Journal of neurology

authors： Meyer BU,Britton TC,Benecke R

更新日期：1989-02-01 00:00:00

abstract：:Patients with multiple system atrophy (MSA) often have evidence of compromised gastrointestinal motility. Ghrelin is a gut hormone that influences gastrointestinal motility in humans. The aim of this study was to determine whether ghrelin secretion is affected in MSA patients, and to investigate the relation between g...

journal_title：Journal of neurology

authors： Ozawa T,Tokunaga J,Arakawa M,Ishikawa A,Takeuchi R,Mezaki N,Miura T,Sakai N,Hokari M,Takeshima A,Utsumi K,Kondo T,Yokoseki A,Nishizawa M

更新日期：2013-08-01 00:00:00

abstract：:Rodent oligodendrocytes have a unique susceptibility among glia to the lytic effects of complement, due in part to a deficiency in CD59 (protectin), a key surface inhibitor of the complement membrane attack complex (MAC). The possibility that shedding of CD59 by human oligodendrocytes contributes to complement-mediate...

journal_title：Journal of neurology

authors： Roddy J,Clark I,Hazleman BL,Compston DA,Scolding NJ

更新日期：1994-08-01 00:00:00