Comparison of CMT1A and CMT2: similarities and differences.

abstract：:A 57-year-old male was repeatedly admitted to hospital because of complex neurological symptoms, including radicular pain, disturbance of micturition, seizures, and severely impaired mental state. The diagnosis was encephalomyeloradiculitis possibly of viral origin, and treatment with immunosuppressants was initiated....

journal_title：Journal of neurology

authors： Kollikowski HH,Schwendemann G,Schulz M,Wilhelm H,Lehmann HJ

更新日期：1988-01-01 00:00:00

abstract：:Central nervous system localizations of sarcoidosis may be refractory to conventional treatment such as steroids and immunosuppressive drugs. Infliximab, a TNF-α antagonist chimeric antibody, has been shown to be effective for treatment of these localizations. The aim of this study was to evaluate the efficacy and saf...

journal_title：Journal of neurology

authors： Cohen Aubart F,Bouvry D,Galanaud D,Dehais C,Mathey G,Psimaras D,Haroche J,Pottier C,Hie M,Mathian A,Devilliers H,Nunes H,Valeyre D,Amoura Z

更新日期：2017-05-01 00:00:00

abstract：:Stavudine (2',3'-didehydro-3'deoxythymidine) is a pyrimidine analogue that may be of great value in combination antiretroviral therapy (ART) for treating patients infected with human immunodeficiency virus type 1 (HIV-1). We assessed potential neurotoxic side effects by comparing peripheral nerve function in patients ...

journal_title：Journal of neurology

authors： von Giesen HJ,Hefter H,Jablonowski H,Arendt G

更新日期：1999-03-01 00:00:00

abstract：:There is increasing evidence that inflammation plays an important role in the progression of acute ischemic stroke (AIS). The primary aims of this study were to examine the serum levels of 13 cytokines, C-reactive protein (CRP), glucose, and hemoglobin in AIS patients, and their relationship to stroke lateralization, ...

journal_title：Journal of neurology

authors： Ormstad H,Aass HC,Lund-Sørensen N,Amthor KF,Sandvik L

更新日期：2011-04-01 00:00:00

abstract：:Acanthocytosis occurs because of ultrastructural abnormalities of the erythrocyte membranous skeleton resulting in reduced membrane fluidity. At least three hereditary neurological conditions are associated with it, although as yet the pathogenesis of the neurological features is unknown. In abetalipoproteinaemia, an ...

journal_title：Journal of neurology

authors： Stevenson VL,Hardie RJ

更新日期：2001-02-01 00:00:00

abstract：:Various ancillary investigations can assist clinicians in the differential diagnosis of patients with parkinsonism. It is unknown which test offers greatest diagnostic value in clinical practice. We included 156 consecutive patients with parkinsonism, but with an initially uncertain diagnosis. At baseline, all patient...

journal_title：Journal of neurology

authors： Aerts MB,Esselink RA,Abdo WF,Meijer FJ,Drost G,Norgren N,Janssen MJ,Borm GF,Bloem BR,Verbeek MM

更新日期：2015-02-01 00:00:00

abstract：:Posterior leukoencephalopathy typically denotes neurotoxicity from immunosuppressive agents, malignant hypertension or eclampsia. It has not been documented in central nervous system angiitis. We present three cases associated with isolated cerebral angiitis after review of all cases of isolated CNS angiitis from 1998...

journal_title：Journal of neurology

authors： Wijdicks EF,Manno EM,Fulgham JR,Giannini C

更新日期：2003-04-01 00:00:00

abstract：:The various clinical features of multiple system atrophy (MSA) make the diagnosis of the disease difficult, especially in its early stages, when signs of differentiated neuroanatomical system involvement have not yet appeared. Mortality studies may be affected by the variability of the diagnostic criteria and selectio...

journal_title：Journal of neurology

authors： Testa D,Filippini G,Farinotti M,Palazzini E,Caraceni T

更新日期：1996-05-01 00:00:00

abstract：:In patients with Parkinson's disease (PD) disturbances of mental state constitute some of the most difficult treatment challenges of advanced disease, often limiting effective treatment of motor symptoms and leading to increased disability and poor quality of life. This article provides an update on the current knowle...

journal_title：Journal of neurology

authors： Schrag A

更新日期：2004-07-01 00:00:00

abstract：:Anti-N-Methyl-D-Aspartate receptor (NMDAR) encephalitis is an acute neurological disorder affecting children and adults. We aimed to compare the clinical characteristics, treatments, and outcomes between children and adults with anti-NMDAR encephalitis and to assess the probable risk factors. In this observational stu...

journal_title：Journal of neurology

authors： Huang Q,Wu Y,Qin R,Wei X,Ma M

更新日期：2016-12-01 00:00:00

abstract：:In the epidemiological area of Southern Lower Saxony 92 patients with clinically definite or probable diagnosis of multiple sclerosis (MS) were interviewed and examined. This group contained a remarkably high percentage of benign cases (52%) in comparison with a sample of hospitalized patients. Neurological examinatio...

journal_title：Journal of neurology

authors： Poser S,Bauer HJ,Ritter G,Friedrich H,Beland H,Denecke P

更新日期：1981-01-01 00:00:00

abstract：:The number of dementia patients requesting euthanasia in the Netherlands has increased over the past five years. The issue is highly controversial. In this contribution we discuss some of the main arguments: the nature of suffering, the voluntariness of the request and the role of the physician. We argue that society ...

journal_title：Journal of neurology

authors： de Beaufort ID,van de Vathorst S

更新日期：2016-07-01 00:00:00

abstract：BACKGROUNDS:Wake-Up Stroke (WUS) patients are generally excluded from thrombolytic therapy (rTPA) due to the unknown time of stroke onset. This study aimed to investigate the effects of rTPA in WUS patients during every day clinical scenarios, by measuring ischemic lesion volume and functional outcomes compared to non-...

journal_title：Journal of neurology

authors： Furlanis G,Ajčević M,Buoite Stella A,Cillotto T,Caruso P,Ridolfi M,Cova MA,Naccarato M,Manganotti P

更新日期：2020-03-01 00:00:00

abstract：:Vanishing white matter disease (VWM) is one of the most prevalent inherited leukoencephalopathies in childhood. Infantile VWM is more severe but less understood than the classic early childhood type. We performed a follow-up study on 14 infantile and 26 childhood patients to delineate the natural history and neuroimag...

journal_title：Journal of neurology

authors： Zhou L,Zhang H,Chen N,Zhang Z,Liu M,Dai L,Wang J,Jiang Y,Wu Y

更新日期：2018-06-01 00:00:00

abstract：:Dimethyl fumarate (DMF), fingolimod (FTY) and teriflunomide (TFN) are oral disease-modifying therapies (DMTs) approved for relapsing-remitting multiple sclerosis (RRMS) whose efficacy and tolerability have been separately assessed in phase III trials. Conversely, little evidence exists about their head-to-head compari...

journal_title：Journal of neurology

authors： Lattanzi S,Danni M,Taffi R,Cerqua R,Carlini G,Pulcini A,Provinciali L,Silvestrini M

更新日期：2017-11-01 00:00:00

abstract：:We present a clinical, neuro-radiological and genetic study on a family with members suffering from an autosomal dominantly inherited syndrome characterised by epilepsy, cerebral calcifications and cysts, bone abnormalities; progressive neuro-cognitive deterioration and paranasal sinusitis. This syndrome shares severa...

journal_title：Journal of neurology

authors： Karlinger K,Tárnoki ÁD,Tárnoki DL,Polvi A,Lehesjoki AE,Kelemen A,Szegedi L,Turányi E,Kamondi A,Szűcs A

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Volume loss in the deep gray matter (DGM) has been reported in patients with multiple sclerosis (MS) already at early stages of the disease and is thought to progress throughout the disease course. OBJECTIVE:To investigate the impact and predictive value of volume loss in DGM and thalamic subnuclei on disab...

journal_title：Journal of neurology

authors： Magon S,Tsagkas C,Gaetano L,Patel R,Naegelin Y,Amann M,Parmar K,Papadopoulou A,Wuerfel J,Stippich C,Kappos L,Chakravarty MM,Sprenger T

更新日期：2020-05-01 00:00:00

abstract：:The objective of this study is to determine the current distribution of clinical phenotypes and to estimate future trends of ALS incidence in Western societies. We report on a clinical-epidemiological registry with a capture-recapture rate of >80% and population-based case-control study in ALS patients in South Wester...

journal_title：Journal of neurology

authors： Rosenbohm A,Peter RS,Erhardt S,Lulé D,Rothenbacher D,Ludolph AC,Nagel G,ALS Registry Study Group.

更新日期：2017-04-01 00:00:00

abstract：:Thirty-seven Japanese autopsy cases with diffuse Lewy body disease (DLBD) were reviewed from a clinicopathological viewpoint. Based on the neuropathological finding of whether or not many concomitant senile plaques (SPs) and/or neurofibrillary tangles (NFTs) are present. DLBD is divided into two forms: a common form a...

journal_title：Journal of neurology

authors： Kosaka K

更新日期：1990-06-01 00:00:00

abstract：:Current findings suggest that multipotent stem cells may be suitable for cell replacement therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are pluripotent cells isolated from the inner cell mass of the preimplantation blastocyst, which give rise to all cells in the organism. Similar...

journal_title：Journal of neurology

authors： Gerlach M,Braak H,Hartmann A,Jost WH,Odin P,Priller J,Schwarz J

更新日期：2002-10-01 00:00:00

abstract：:The relationship between atherosclerosis and cognitive function is less well studied in Chinese populations. In addition, the results among middle-aged adults have been mixed. We aimed to investigate the association of atherosclerosis measured by carotid intima-media thickness (CIMT) and cognitive function in middle-a...

journal_title：Journal of neurology

authors： Wang A,Chen G,Su Z,Liu X,Yuan X,Jiang R,Cao Y,Chen S,Luo Y,Guo X,Wu S,Zhao X

更新日期：2016-10-01 00:00:00

abstract：:Elevated intracranial intravenous pressure is not routinely measured in clinical practice. Indirect evidence of increased venous pressure is reflected in the size change of the cerebral sinuses and the presence of venous infarctions. The purpose of this study is to evaluate the role of brain perfusion venous time-dens...

journal_title：Journal of neurology

authors： Darwish RS,Amiridze NS

更新日期：2011-08-01 00:00:00

abstract：:Cobrotoxin-binding protein was isolated by affinity chromatography from human thymoma which had been surgically removed from patients with myasthenia gravis. The protein was composed of polypeptides with a molecular mass of 40, 51, 65, and 74 kilodaltons as determined by polyacrylamide gel electrophoresis in the prese...

journal_title：Journal of neurology

authors： Kawanami S,Kamei H,Oita J,Kurokawa M,Uchida Y,Hayashi K

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Hyposmia can develop with age and in neurodegenerative conditions, including Parkinson's disease (PD). The University of Pennsylvania Smell Identification Test (UPSIT) is a 40-item smell test widely used for assessing hyposmia. However, in a number of situations, such as identifying hyposmic individuals in l...

journal_title：Journal of neurology

authors： Joseph T,Auger SD,Peress L,Rack D,Cuzick J,Giovannoni G,Lees A,Schrag AE,Noyce AJ

更新日期：2019-08-01 00:00:00

abstract：:Sera from 23 patients with acute Guillain Barré syndrome (GBS), 15 patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and from 40 age-matched blood donors were analysed for antibodies to acidic glycosphingolipids from human brain and peripheral nerve. Antibodies to ganglioside LM1, the majo...

journal_title：Journal of neurology

authors： Fredman P,Vedeler CA,Nyland H,Aarli JA,Svennerholm L

更新日期：1991-04-01 00:00:00

abstract：:In 12 ambulant patients with a clinical diagnosis of probable Alzheimer's disease, a 12-week, double-blind, placebo-controlled study with 100 mg/day tetrahydroaminoacridine (THA) and 10 g/day lecithin is reported. The aim of the study was to find whether treatment would result in an improvement of cognition, of functi...

journal_title：Journal of neurology

authors： Weinstein HC,Teunisse S,van Gool WA

更新日期：1991-02-01 00:00:00

abstract：:The etiology of spontaneous cervical artery dissection (sCAD) is unknown. An underlying connective tissue disorder has been suggested. As a collagen disease is conceivable several genes encoding fibrillar collagens have been condsidered as candidate genes for sCAD. We analysed the COL3A1 gene in patients with spontane...

journal_title：Journal of neurology

authors： von Pein F,Välkkilä M,Schwarz R,Morcher M,Klima B,Grau A,Ala-Kokko L,Hausser I,Brandt T,Grond-Ginsbach C

更新日期：2002-07-01 00:00:00

abstract：:Brain metastases occur in 20-40% of patients with cancer and their frequency has increased over time. Lung, breast and skin (melanoma) are the commonest sources of brain metastases, and in up to 15% of patients the primary site remains unknown. After the introduction of MRI, multiple lesions have outnumbered single le...

journal_title：Journal of neurology

authors： Soffietti R,Rudā R,Mutani R

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:Sporadic (SSP) and hereditary spastic paraplegias (HSP) are clinically and genetically heterogeneous disorders, which are characterised by a slowly progressive spastic paraparesis. Initial symptoms and the rate of progression are variable even among members of the same family. Spastic paraparesis is the majo...

journal_title：Journal of neurology

authors： Klebe S,Stolze H,Kopper F,Lorenz D,Wenzelburger R,Volkmann J,Porschke H,Deuschl G

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To assess the association of Medial Temporal lobe Atrophy (MTA) and White Matter Hyperintensities (WMHs) with gray matter perfusion in Mild Cognitive Impairment (MCI). METHODS:56 MCI patients (age = 69.3 +/- 7.0, 32 females) underwent brain MR scan and (99m)Tc ECD SPECT. We evaluated MTA according to Schelte...

journal_title：Journal of neurology

authors： Caroli A,Testa C,Geroldi C,Nobili F,Guerra UP,Bonetti M,Frisoni GB

更新日期：2007-08-01 00:00:00