Volume loss in the deep gray matter and thalamic subnuclei: a longitudinal study on disability progression in multiple sclerosis.

abstract：:Augmented spinal nociception during the "off" phase has been observed early in Parkinson's disease further increasing with disease duration. To find out whether increased spinal nociception represents a premotor feature, experimental pain sensitivity was assessed in idiopathic REM-sleep behavior disorder (IRBD) patien...

journal_title：Journal of neurology

authors： Boura E,Stamelou M,Vadasz D,Ries V,Unger MM,Kägi G,Oertel WH,Möller JC,Mylius V

更新日期：2017-03-01 00:00:00

abstract：:The aim of this work was to determine whether survival changed during 2002-2009 at a French amyotrophic lateral sclerosis (ALS) center. We included all patients with ALS who were seen consecutively at the center from January 2002-May 2009. Participants were followed from date of first visit through death, date of cens...

journal_title：Journal of neurology

authors： Gordon PH,Salachas F,Bruneteau G,Pradat PF,Lacomblez L,Gonzalez-Bermejo J,Morelot-Panzini C,Similowski T,Elbaz A,Meininger V

更新日期：2012-09-01 00:00:00

abstract：:The Richards-Rundle syndrome (RRS) is characterized by hearing loss, mental deterioration, ataxia, primary hypogonadism and autosomal recessive transmission. In a sibship of six members we found two sisters with RRS together with baldness, impaired GH and PRL secretion after stimulation and different degrees of impair...

journal_title：Journal of neurology

authors： Franceschi M,Parmigiani F,Zamproni P,Cairoli G,Canal N

更新日期：1984-01-01 00:00:00

abstract：:Thirty-five patients with intraventricular haemorrhage shown by CT underwent cerebral arteriography. In 15 patients arteriography showed an occlusion of a carotid or middle cerebral artery. Secondary bleeding into an infarction caused the intraventricular haemorrhage. All 15 patients were aged over 40 years. ...

journal_title：Journal of neurology

authors： Cohn DF,Avrahami E

更新日期：1983-01-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating disease of the brain caused by the JC virus that occurs mainly in immunocompromised patients. The prognosis is very poor. As the lesion looks like non- specific leukoencephalopathy, making a diagnosis at the early stage is very difficult. We ...

journal_title：Journal of neurology

authors： Shirai S,Yabe I,Kano T,Shimizu Y,Sasamori T,Sato K,Hirotani M,Nonaka T,Takahashi I,Matsushima M,Minami N,Nakamichi K,Saijo M,Hatanaka KC,Shiga T,Tanaka S,Sasaki H

更新日期：2014-12-01 00:00:00

abstract：:In refractory temporal lobe epilepsy (TLE) temporal lobe structures and functions are continuously or intermittently affected by abnormal brain electrical events, noxious neurochemical agents, and metabolic disturbances. There is conflicting evidence regarding the relationship between the duration of refractory mesial...

journal_title：Journal of neurology

authors： Jokeit H,Ebner A,Arnold S,Schüller M,Antke C,Huang Y,Steinmetz H,Seitz RJ,Witte OW

更新日期：1999-10-01 00:00:00

abstract：:Therapeutic apheresis has emerged as a major treatment option for autoantibody-associated inflammatory diseases of the nervous system. This includes patients with autoimmune encephalitides caused by antibodies against neuronal proteins. Plasma exchange (PE) and immunoadsorption (IA) constitute two possibilities to eli...

journal_title：Journal of neurology

authors： Heine J,Ly LT,Lieker I,Slowinski T,Finke C,Prüss H,Harms L

更新日期：2016-12-01 00:00:00

abstract：:Based on the observation of bilateral temporoparietal hypoperfusion in Alzheimer's disease (AD), single photon emission computed tomography (SPECT) is advocated by some as a powerful diagnostic tool in the evaluation of demented patients. We studied whether routine brain SPECT in elderly, mildly demented outpatients i...

journal_title：Journal of neurology

authors： Van Gool WA,Walstra GJ,Teunisse S,Van der Zant FM,Weinstein HC,Van Royen EA

更新日期：1995-06-01 00:00:00

abstract：:We review the neuronal antibodies described in CNS disorders in order to clarify their diagnostic value, emphasize potentials pitfalls and limitations in the diagnosis of paraneoplastic neurological syndromes (PNS), and examine the current evidence for a possible pathogenic role. We propose to classify the neuronal an...

journal_title：Journal of neurology

authors： Graus F,Saiz A,Dalmau J

更新日期：2010-04-01 00:00:00

abstract：:Clinical data and the serum and cerebrospinal fluid (CSF) findings of 71 patients with Guillain-Barré syndrome (GBS), 7 with Fisher syndrome and 24 with chronic inflammatory polyradiculoneuropathy (CIP), were analysed. Isoelectric focusing of serum and CSF together with different formulae and diagrams were applied to ...

journal_title：Journal of neurology

authors： Segurado OG,Krüger H,Mertens HG

更新日期：1986-08-01 00:00:00

abstract：:Secondary worsening of stroke symptoms is described in 13-37% of stroke patients, but the exact mechanism of this phenomenon remains unclear. The aim of this study is to find prognostic variables in correlation to secondary worsening of stroke symptoms in patients with lacunar or cortical strokes. In this prospective ...

journal_title：Journal of neurology

authors： Schweitzer JR,Koehler PJ,Voogd AC,Franke CL

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To identify factors that impact on the ability of patients with multiple sclerosis (MS) to remain in work in order to make recommendations for future clinical management. METHODS:Cross-sectional studies using qualitative (phase one) and quantitative (phase two) methods. In phase one, 62 patients were intervi...

journal_title：Journal of neurology

authors： O'Connor RJ,Cano SJ,Ramió i Torrentà L,Thompson AJ,Playford ED

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:The variability of the severity and regional distribution of pathological process in basal ganglia (BG) and brainstem-cerebellar systems results in clinical heterogeneity and represents the motor subtype of multiple system atrophy (MSA). This study aimed to quantify spatial patterns of multimodal MRI abnormal...

journal_title：Journal of neurology

authors： Lee MJ,Kim TH,Mun CW,Shin HK,Son J,Lee JH

更新日期：2018-07-01 00:00:00

abstract：:Levodopa therapy is essential for patients in the advanced stages of Parkinson's disease. However, at early stages, DA agonist therapy has similar efficacy in the treatment of parkinsonism and a lower incidence of motor complications compared to levodopa therapy several years after the initiation of the therapy. The m...

journal_title：Journal of neurology

authors： Kondo T

更新日期：2002-09-01 00:00:00

abstract：:Small retrospective case series suggest that decompressive hemicraniectomy can be life saving in patients with cerebral venous thrombosis (CVT) and impending brain herniation. Prospective studies of consecutive cases are lacking. Thus, a single centre, prospective study was performed. In 2006 we adapted our protocol f...

journal_title：Journal of neurology

authors： Zuurbier SM,Coutinho JM,Majoie CB,Coert BA,van den Munckhof P,Stam J

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Cerebral venous thrombosis (CVT) is associated with intracranial hemorrhage. AIM:To identify clinical and imaging features of CVT-associated intracranial hemorrhage. We hypothesized that higher clot burden would be associated with a higher risk of intracranial hemorrhage. METHODS:We performed a retrospecti...

journal_title：Journal of neurology

authors： Afifi K,Bellanger G,Buyck PJ,Zuurbier SM,Esperon CG,Barboza MA,Costa P,Escudero I,Renard D,Lemmens R,Hinteregger N,Fazekas F,Conde JJ,Giralt-Steinhauer E,Hiltunen S,Arauz A,Pezzini A,Montaner J,Putaala J,Weimar C,

更新日期：2020-11-01 00:00:00

abstract：:Multifocal motor neuropathy (MMN) can be differentiated from motor neuron disease by electrophysiological evidence of conduction block. To increase the probability of recording conduction block, we studied the whole nerve length including proximal segments in 84 patients with pure motor syndromes, using a special stim...

journal_title：Journal of neurology

authors： Jaspert A,Claus D,Grehl H,Neundörfer B

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Since the detection of autoantibodies against neuronal surface antigens, autoimmune encephalitis (AE) has been more frequently diagnosed, especially in patients with symptoms typical of limbic encephalitis, such as seizures, short-term memory deficits, or psychosis. However, the clinical spectrum of AE may b...

journal_title：Journal of neurology

authors： Baumgartner A,Rauer S,Hottenrott T,Leypoldt F,Ufer F,Hegen H,Prüss H,Lewerenz J,Deisenhammer F,Stich O

更新日期：2019-01-01 00:00:00

abstract：:Motor tests were performed in 50 HIV-infected patients in all stages according to the current CDC classification, but without any clinically evident central nervous system deficit, and the results compared with an age-matched control group. Patients were excluded from the study if there was alcohol or drug abuse, feve...

journal_title：Journal of neurology

authors： Arendt G,Hefter H,Elsing C,Strohmeyer G,Freund HJ

更新日期：1990-10-01 00:00:00

abstract：:To evaluate the clinical and electrophysiological similarities and differences between two large groups of patients with Charcot-Marie-Tooth disease, i.e. CMT1A and CMT2, we performed a post hoc comparison of clinical and electrophysiological data. Most CMT1A and CMT2 patients had the classical CMT phenotype. Age of o...

journal_title：Journal of neurology

authors： Bienfait HM,Verhamme C,van Schaik IN,Koelman JH,de Visser BW,de Haan RJ,Baas F,van Engelen BG,de Visser M

更新日期：2006-12-01 00:00:00

abstract：:We report the case of a 17.5-year old girl with generalized myasthenia gravis (MG). When she was 13, she started to complain of episodic diplopia, ptosis and mild fatigability of upper and lower extremity muscles. She was diagnosed with MG 3 years later, after exacerbation of her limb muscle weakness. Acetylcholine re...

journal_title：Journal of neurology

authors： Kostera-Pruszczyk A,Kwiecinski H

更新日期：2009-10-01 00:00:00

abstract：:Autosomal recessive cerebellar ataxia type 3 (ARCA3) is a rare inherited disorder caused by mutations in the ANO10 gene. The disease is characterized by slowly progressive spastic ataxia variably associated with motor neuron involvement, epilepsy, and cognitive decline. We performed mutational screening in 80 patients...

journal_title：Journal of neurology

authors： Nanetti L,Sarto E,Castaldo A,Magri S,Mongelli A,Rossi Sebastiano D,Canafoglia L,Grisoli M,Malaguti C,Rivieri F,D'Amico MC,Di Bella D,Franceschetti S,Mariotti C,Taroni F

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Diagnostic delay of hereditary transthyretin amyloidosis (ATTRv, v for variant) prevents timely treatment and, therefore, concurs to the mortality of the disease. The aim of the present study was to explore with nerve ultrasound (US) possible red flags for early diagnosis in ATTRv patients with carpal tunnel...

journal_title：Journal of neurology

authors： Salvalaggio A,Coraci D,Cacciavillani M,Obici L,Mazzeo A,Luigetti M,Pastorelli F,Grandis M,Cavallaro T,Bisogni G,Lozza A,Gemelli C,Gentile L,Ermani M,Fabrizi GM,Plasmati R,Campagnolo M,Castellani F,Gasparotti R,Marti

更新日期：2021-01-01 00:00:00

abstract：BACKGROUNDS:Wake-Up Stroke (WUS) patients are generally excluded from thrombolytic therapy (rTPA) due to the unknown time of stroke onset. This study aimed to investigate the effects of rTPA in WUS patients during every day clinical scenarios, by measuring ischemic lesion volume and functional outcomes compared to non-...

journal_title：Journal of neurology

authors： Furlanis G,Ajčević M,Buoite Stella A,Cillotto T,Caruso P,Ridolfi M,Cova MA,Naccarato M,Manganotti P

更新日期：2020-03-01 00:00:00

abstract：:Freezing of gait (FOG) is a disabling motor symptom experienced by a large proportion of patients with Parkinson's disease (PD). While it is known that FOG contributes to lower health-related quality of life (HRQoL), previous studies have not accounted for other important factors when measuring the specific impact of ...

journal_title：Journal of neurology

authors： Walton CC,Shine JM,Hall JM,O'Callaghan C,Mowszowski L,Gilat M,Szeto JY,Naismith SL,Lewis SJ

更新日期：2015-01-01 00:00:00

abstract：:Sensory trick may relieve dystonic symptoms in patients with idiopathic cervical dystonia (CD). We investigated the patterns of brain functional MRI (fMRI) during resting state, sensory trick simulation and sensory trick imagination in CD patients both with and without an effective sensory trick. We recruited 17 CD pa...

journal_title：Journal of neurology

authors： Sarasso E,Agosta F,Piramide N,Bianchi F,Butera C,Gatti R,Amadio S,Del Carro U,Filippi M

更新日期：2020-04-01 00:00:00

abstract：:We hypothesize that cerebral microbleeds (CMB) in patients with different neuropsychological profiles (amnestic or non-amnestic) and MRI features of vascular damage could provide important information on the underlying pathological process in early Alzheimer's disease. The study was performed at two trial sites. We st...

journal_title：Journal of neurology

authors： Poliakova T,Levin O,Arablinskiy A,Vasenina E,Zerr I

更新日期：2016-10-01 00:00:00

abstract：:Recent genetic studies suggest a Sardinian type of amyotrophic lateral sclerosis (ALS). Thus, ALS incidence, prevalence and survival were investigated in a large population of Sardinians aimed to disclose population-specific patterns and their temporal changes. This is a population-based incidence and prevalence study...

journal_title：Journal of neurology

authors： Pugliatti M,Parish LD,Cossu P,Leoni S,Ticca A,Saddi MV,Ortu E,Traccis S,Borghero G,Puddu R,Chiò A,Pirina P

更新日期：2013-02-01 00:00:00

abstract：:The age-related structural changes of the human hippocampus are not entirely understood. The goal of the present investigation was to understand better the nature of age-related hippocampal changes by a comparative MR-analysis of four complementary aspects of hippocampal integrity: total volume, metabolite concentrati...

journal_title：Journal of neurology

authors： Szentkuti A,Guderian S,Schiltz K,Kaufmann J,Münte TF,Heinze HJ,Düzel E

更新日期：2004-11-01 00:00:00

abstract：:Two patients are described, in whom MRI detected unilateral signal abnormalities in the region of the inferior olivary nuclei, suggesting an early stage of olivary hypertrophy. MRI was performed 4 and 7 weeks respectively after traumatic brain-stem injury. Palatal myoclonus was concomitantly observed in one patient, w...

journal_title：Journal of neurology

authors： Birbamer G,Buchberger W,Kampfl A,Aichner F

更新日期：1993-07-01 00:00:00