Ocular hypertension and diabetes mellitus in the Beijing Eye Study.


PURPOSE:To determine prevalence and associated factors of ocular hypertension in the adult Chinese population. METHODS:The Beijing Eye Study, a population-based prevalence study, included 4439 subjects out of 5324 subjects with an age of 40+ years invited to participate (response rate 83.4%). From the 4439 individuals, 4224 (95.2%) subjects fulfilled the inclusion criteria of the present study, that is, available readable optic disc photographs, a nonglaucomatous appearance of the optic disc, and a normal visual field in the case of an intraocular pressure higher than 21 mm Hg. The participants underwent an interview, a detailed ophthalmic examination, blood pressure measurements, and examination of blood samples. Ocular hypertension was defined as an intraocular pressure higher than 21 mm Hg with a normal appearance of the optic nerve head and no defects in frequency doubling perimetry. RESULTS:Ocular hypertension was detected in 299 (3.6%) eyes (prevalence rate: 3.63%+/-0.21%) of 160 (3.8%) subjects (prevalence rate: 3.79%+/-0.29%). In multiple regression analysis, ocular hypertension was significantly associated with serum levels of cholesterol [P=0.006; odds ratio (OR): 1.34; 95% confidence interval (CI): 1.09-1.64], presence of diabetes mellitus (P=0.03; OR: 1.45; 95% CI: 1.04-2.07) and arterial hypertension (P<0.001; OR: 3.18; 95% CI: 1.86-5.43). Ocular hypertension was not significantly associated with age, sex, urban or rural region, refractive error, anterior chamber depth, optic disc area, and area of beta zone of parapapillary atrophy. CONCLUSIONS:Ocular hypertension has a frequency of about 3.6% in the adult Chinese population with an age of 40+ years. Associated factors are diabetes mellitus, arterial hypertension, and elevated serum cholesterol levels. Diabetes mellitus, arterial hypertension, and elevated serum cholesterol concentrations should be checked in ocular hypertensive subjects.


J Glaucoma


Journal of glaucoma


Xu L,Wang YX,Jonas JB,Wang YS,Wang S




Has Abstract


2009-01-01 00:00:00














  • Preliminary Report on a Novel Virtual Reality Perimeter Compared With Standard Automated Perimetry.

    abstract:PRECIS:The VisuALL head-mounted perimetry in normal subjects and glaucoma patients had a moderate to strong correlation with the Humphrey Field Analyzer (HFA). PURPOSE:Visual field testing has a vital role in diagnosing and managing glaucoma. The current clinical practice relies on large, table-based testing units. Th...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Razeghinejad R,Gonzalez-Garcia A,Myers JS,Katz LJ

    更新日期:2021-01-01 00:00:00

  • Macular and retinal nerve fiber layer thickness measurement reproducibility using optical coherence tomography (OCT-3).

    abstract:PURPOSE:To assess the reproducibility of retinal nerve fiber layer thickness and macular thickness measurements using OCT-3. METHODS:Randomly chosen eyes of healthy individuals were scanned following pupillary dilation by two trained operators (RGO, RV) using OCT-3 (software version A1.1, Carl Zeiss Meditec, Inc., Dub...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Gürses-Ozden R,Teng C,Vessani R,Zafar S,Liebmann JM,Ritch R

    更新日期:2004-06-01 00:00:00

  • Reproducibility of the new Goldmann AT900D digital tonometer.

    abstract:PURPOSE:To examine the reproducibility of the new digital Goldmann applanation tonometer AT 900D (DGT) for measuring intraocular pressure and to compare its readings with those provided by the conventional analog Goldmann tonometer (AGT). METHODS:In 3 different sessions (S1, S2, and S3), 3 intraocular pressure measure...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Morales-Fernandez L,Martinez-de-la-Casa JM,Garcia-Feijoo J,Saenz-Frances F,Santos-Bueso E,Garcia-Sanchez J

    更新日期:2012-03-01 00:00:00

  • Effects of Nonporous Silica Nanoparticles on Human Trabecular Meshwork Cells.

    abstract:PRECIS:Silica nanoparticles (SiNPs), which are potential drug carriers for glaucoma treatment, may induce mild dose-dependent cytotoxicity but not so severe as to compromise a mammalian target of rapamycin (mTOR) pathway in immortalized trabecular meshwork (TM) cells. PURPOSE:Nanoparticle-based ophthalmic drug deliver...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Kim M,Park JH,Jeong H,Hong J,Park CY

    更新日期:2021-02-01 00:00:00

  • Three-Year Follow-up of a Novel Aqueous Humor MicroShunt.

    abstract:AIMS:An observational study to determine the safety and efficacy of filtering surgery employing a microlumen aqueous drainage device (InnFocus MicroShunt), used intraoperatively with Mitomycin C, implanted alone or in combination with phacoemulsification. MATERIALS AND METHODS:Single-site, prospective, nonrandomized s...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Batlle JF,Fantes F,Riss I,Pinchuk L,Alburquerque R,Kato YP,Arrieta E,Peralta AC,Palmberg P,Parrish RK 2nd,Weber BA,Parel JM

    更新日期:2016-02-01 00:00:00

  • Transscleral contact krypton laser cyclophotocoagulation for treatment of posttraumatic glaucoma.

    abstract:PURPOSE:To evaluate the usefulness of the krypton laser for transscleral contact cyclophotocoagulation in the treatment of posttraumatic glaucoma. PATIENTS AND METHODS:A total of 18 eyes of 18 patients with therapy-resistant posttraumatic glaucoma treated with krypton laser cyclophotocoagulation from 1991 to 1996 were...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Raivio VE,Immonen IJ,Laatikainen LT,Puska PM

    更新日期:2001-04-01 00:00:00

  • Plasma Homocysteine, Serum Folic Acid, Serum Vitamin B12, Serum Vitamin B6, MTHFR, and Risk of Normal-Tension Glaucoma.

    abstract:BACKGROUND:This meta-analysis aims to comprehensively evaluate the association between total homocysteine (tHcy) levels, serum folic acid, vitamin B12, vitamin B6 levels, methylenetetrahydrofolate reductase (MTHFR) C677T genotype, and risk of normal-tension glaucoma (NTG). MATERIALS AND METHODS:A systematic search of ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,meta分析


    authors: Li J,Xu F,Zeng R,Gong H,Lan Y

    更新日期:2016-02-01 00:00:00

  • Comparison of fluctuations of intraocular pressure before and after selective laser trabeculoplasty in normal-tension glaucoma patients.

    abstract:PURPOSE:The aim of this study was to examine the effects of selective laser trabeculoplasty (SLT) treatment on habitual intraocular pressure (IOP) fluctuations in patients with normal-tension glaucoma (NTG) using a SENSIMED Triggerfish contact lens sensor (CLS). MATERIALS AND METHODS:Ten patients diagnosed with NTG we...

    journal_title:Journal of glaucoma

    pub_type: 临床试验,杂志文章


    authors: Tojo N,Oka M,Miyakoshi A,Ozaki H,Hayashi A

    更新日期:2014-10-01 00:00:00

  • Acute angle-closure glaucoma in a patient with miller fisher syndrome without pupillary dysfunction.

    abstract:PURPOSE:To report a case of an angle-closure glaucoma in a patient with Miller Fisher syndrome (MFS) without pupillary dysfunction. METHODS:We present a case report of a 75-year-old male presenting with total ophthalmoplegia, complete bilateral ptosis, and gait disturbance. He was diagnosed with MFS without pupillary ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Ryu WY,Kim JK,Jin SW,Shim DH

    更新日期:2015-02-01 00:00:00

  • Surgical output and clinic burden of glaucoma in lagos, Nigeria.

    abstract:PURPOSE:To estimate the outpatient clinic burden and surgical workload related to glaucoma in Lagos, Nigeria. METHODS:A multicentre study involving the 2 tertiary eye institutions, 7 secondary eye centers with eye care facilities, and the largest private eye hospital in Lagos state, Nigeria. Data on outpatient departm...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,多中心研究


    authors: Adekoya BJ,Onakoya AO,Shah SP,Adepoju FG

    更新日期:2014-01-01 00:00:00

  • Oxidative stress in primary open-angle glaucoma.

    abstract:PURPOSE:To analyze oxidative stress in primary open-angle glaucoma (POAG). MATERIAL AND METHODS:A case-control study including 90 eyes of 90 patients who needed antiglaucomatous surgery in the course of POAG (glaucoma group, n=50) and from patients who were operated of nonpathologic cataracts (cataract group, n=40). F...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Zanon-Moreno V,Marco-Ventura P,Lleo-Perez A,Pons-Vazquez S,Garcia-Medina JJ,Vinuesa-Silva I,Moreno-Nadal MA,Pinazo-Duran MD

    更新日期:2008-06-01 00:00:00

  • The Italian version of the Glaucoma Symptom Scale Questionnaire: translation, validation, and reliability.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Rossi GC,Pasinetti GM,Scudeller L,Milano G,Mazzone A,Raimondi M,Bordin M,Lanteri S,Bianchi PE

    更新日期:2013-01-01 00:00:00

  • Evaluation of the whole-field scotopic retinal sensitivity tester in clinical glaucoma practice.

    abstract::We determined the results of routine whole-field scotopic vision testing in consecutive patients with ocular hypertension or glaucoma who underwent Humphrey automated perimetric testing and optic disc examination. In 39 ocular hypertensive patients we found a mean threshold of 16.7 +/- 7.4 dB and in 61 glaucoma patien...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Stewart WC,Chorak RP,Murrell HP

    更新日期:1994-01-01 00:00:00

  • Relationship Between Serum Glucose Levels and Intraocular Pressure, a Population-based Cross-sectional Study.

    abstract:PURPOSE:The purpose of this study is to assess the relationship between serum glucose levels and intraocular pressure (IOP) both in subjects with impaired fasting glucose (IFG) as well as in subjects with diabetes mellitus (DM). MATERIALS AND METHODS:Data of a cross-sectional sample of 18,406 subjects who underwent ro...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Cohen E,Kramer M,Shochat T,Goldberg E,Krause I

    更新日期:2017-07-01 00:00:00

  • Comparison of Ab Externo and Ab Interno 360-degree Suture Trabeculotomy in Adult Open-angle Glaucoma.

    abstract:PRECIS:Ab interno (gonioscopy-assisted transluminal trabeculotomy) and ab externo 360-degree suture trabeculotomy (ST) achieved similar success rates for reducing intraocular pressure (IOP) without serious complications threatening visual acuity. PURPOSE:We aimed to compare the efficacy of ab externo and ab interno 36...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Yalinbas D,Dilekmen N,Hepsen IF

    更新日期:2020-11-01 00:00:00

  • A Comparative Analysis of Goldmann Tonometry Correction.

    abstract:PURPOSE:The measurement of intraocular pressure (IOP) by Goldmann applanation tonometry (GAT) is based on assumptions about corneal parameters. To correct for variations in corneal curvature and thickness, a number of equations have been proposed. This study evaluates the in vivo accuracy of these equations from indivi...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Asejczyk-Widlicka M,Srodka W,Pierscionek BK

    更新日期:2017-03-01 00:00:00

  • High failure rate associated with 180 degrees selective laser trabeculoplasty.

    abstract:PURPOSE:To determine the efficacy of selective laser trabeculoplasty (SLT) in a tertiary care referral center. PATIENTS AND METHODS:In this retrospective study of selective laser trabeculoplasty performed by five physicians, 94 eyes from 94 patients were included. A majority (83/92, 90%) underwent 180 degrees selectiv...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Song J,Lee PP,Epstein DL,Stinnett SS,Herndon LW Jr,Asrani SG,Allingham RR,Challa P

    更新日期:2005-10-01 00:00:00

  • Risk Factors Associated With Glaucomatous Progression in Pseudoexfoliation Patients.

    abstract:PURPOSE:To investigate risk factors associated with glaucomatous progression in pseudoexfoliation glaucoma (PXG) patients. PATIENTS AND METHODS:A retrospective observational study with a total of 48 PXG patients and age, sex, and visual field (VF) test mean deviation-matched 48 primary open-angle glaucoma (POAG) patie...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,多中心研究


    authors: Moon Y,Sung KR,Kim JM,Shim SH,Yoo C,Park JH

    更新日期:2017-12-01 00:00:00

  • Two-year Results After Deep Sclerectomy With Nonabsorbable Uveoscleral Implant (Esnoper-Clip): Surgical Area Analysis Using Anterior Segment Optical Coherence Tomography.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Romera-Romero P,Loscos-Arenas J,Moll-Udina A,Romanic-Bubalo N,Castellvi-Manent J,Valldeperas X

    更新日期:2017-10-01 00:00:00

  • The Short-term Effect of Subtenon Sponge Application Versus Subtenon Irrigation of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration Device: A Randomized Trial.

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    journal_title:Journal of glaucoma

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    authors: Quist MS,Brown N,Bicket AK,Herndon LW

    更新日期:2018-02-01 00:00:00

  • Ab Interno Tube Occlusion for Postoperative Hypotony in a Patient With an Ahmed Glaucoma Drainage Device.

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    journal_title:Journal of glaucoma

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    authors: Feinstein M,Moussa K,Han Y

    更新日期:2018-03-01 00:00:00

  • Activation of elastin mRNA expression in human optic nerve heads with primary open-angle glaucoma.

    abstract::Elastin is the major protein of elastic fibers and is responsible for the elastic recoil. Elastic fibers are a major component of the extracellular matrix in the human lamina cribrosa and undergo marked changes in primary open-angle glaucoma. Ultrastructural and immunocytochemical analysis demonstrated fragmentation o...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Hernandez MR,Yang J,Ye H

    更新日期:1994-10-01 00:00:00

  • Reproducibility of retinal nerve fiber thickness measurements using the test-retest function of spectral OCT/SLO in normal and glaucomatous eyes.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Lee SH,Kim SH,Kim TW,Park KH,Kim DM

    更新日期:2010-12-01 00:00:00

  • Changes in scanning laser polarimetry before and after laser capsulotomy for posterior capsular opacification.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Brittain CJ,Fong KC,Hull CC,Gillespie IH

    更新日期:2007-01-01 00:00:00

  • A comparison of intraocular pressure measurements with the XPERT noncontact tonometer and Goldmann applanation tonometry.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Popovich KS,Shields MB

    更新日期:1997-02-01 00:00:00

  • Effect of Toric Intraocular Lens Implantation on Visual Acuity and Astigmatism Status in Eyes Treated With Microhook Ab Interno Trabeculotomy.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Ichioka S,Manabe K,Tsutsui A,Takai Y,Tanito M

    更新日期:2021-01-01 00:00:00

  • Trabeculectomy Following Failed Ab Interno Gelatin Microstent: Case Series.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Gizzi C,Mohamed-Noriega J,Elkarmouty A,Scott A

    更新日期:2018-10-01 00:00:00

  • Long-term Glaucoma Treatment with MK-507, Dorzolamide, a Topical Carbonic Anhydrase Inhibitor.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: MK-507 Clinical Study Group.

    更新日期:1995-02-01 00:00:00

  • A new model of glaucoma filtering surgery in the rat.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Sherwood MB,Esson DW,Neelakantan A,Samuelson DA

    更新日期:2004-10-01 00:00:00

  • Choroidal Microvasculature Dropout is Not Associated With Myopia, But is Associated With Glaucoma.

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    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Shin JW,Kwon J,Lee J,Kook MS

    更新日期:2018-02-01 00:00:00