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Improvement of spontaneous pregnancy rate after stopping gonadotropin therapy for anovulatory infertility.

Abstract：

:In a prospective study, 140 patients with infertility because of ovulatory factors (group A) were followed up for 6 months after failure to achieve pregnancy using human menopausal gonadotropin (hMG) therapy. They included cases of oligomenorrhea, polycystic ovarian disease (PCOD), and hypogonadotropic amenorrhea. They were treated with hMG alone or in combination with clomiphene citrate or gonadotropin-releasing hormone agonist analog. The control group (B) included 83 infertile patients because of similar ovulatory factors. They were followed up for 6 months not preceded by ovulation induction. The overall pregnancy rate (PR) in group A (20.7%) was significantly higher than group B (7.2%). The PR was significantly higher in oligomenorrhea and PCOD patients when compared with the control group. There was no significant difference in the hypogonadotropic group.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Aboulghar MA,Mansour RT,Serour GI,Rizk P,Riad R

doi

10.1016/s0015-0282(16)54237-x

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

722-5

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)54237-X

journal_volume

55

pub_type

临床试验,杂志文章

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