Hydrogels for osteochondral repair based on photocrosslinkable carbamate dendrimers.

abstract：:A unified kinetic pathway for the enzyme-catalyzed polymerization and degradation of poly(ε-caprolactone) was developed. This model tracks the complete distribution of individual chain lengths, both enzyme-bound and in solution, and successfully predicts monomer conversion and the molecular mass distribution as a func...

journal_title：Biomacromolecules

authors： Johnson PM,Kundu S,Beers KL

更新日期：2011-09-12 00:00:00

abstract：:G-quadruplex is a type of DNA secondary structure formed by specific guanine-rich sequences. Because of their enrichment in functional genomic regions and their biological significance, G-quadruplexes are recognized as significant drug targets for cancer and other diseases. Here, we tested the precipitation efficiency...

journal_title：Biomacromolecules

authors： Lin J,Yan YY,Ou TM,Tan JH,Huang SL,Li D,Huang ZS,Gu LQ

更新日期：2010-12-13 00:00:00

abstract：:There is a distinct need for antimicrobial compounds that can act at surfaces without leaching into the environment. Such materials should be easy to synthesize, be easy to apply to surfaces, and display reasonable levels of antimicrobial and antifungal activity. Here we describe such a surface-active compound and dem...

journal_title：Biomacromolecules

authors： Ravikumar T,Murata H,Koepsel RR,Russell AJ

更新日期：2006-10-01 00:00:00

abstract：:Marine mussels tether to seashore surfaces with byssal threads, proteinaceous fibers that effectively dissipate energy from crashing waves. Protein-metal coordination bonds have been proposed to contribute to the characteristic mechanical and self-healing properties of byssal threads; however, very little is understoo...

journal_title：Biomacromolecules

authors： Schmitt CN,Politi Y,Reinecke A,Harrington MJ

更新日期：2015-09-14 00:00:00

abstract：:A heterofunctional support for enzyme immobilization may be defined as that which possesses several distinct functionalities on its surface able to interact with a protein. We will focus on those supports in which a final covalent attachment between the enzyme and the support is achieved. Heterofunctionality sometimes...

journal_title：Biomacromolecules

authors： Barbosa O,Torres R,Ortiz C,Berenguer-Murcia A,Rodrigues RC,Fernandez-Lafuente R

更新日期：2013-08-12 00:00:00

abstract：:Electrospinning for the formation of nanoscale diameter fibers has been explored for high-performance filters and biomaterial scaffolds for vascular grafts or wound dressings. Fibers with nanoscale diameters provide benefits due to high surface area. In the present study we explore electrospinning for protein-based bi...

journal_title：Biomacromolecules

authors： Jin HJ,Fridrikh SV,Rutledge GC,Kaplan DL

更新日期：2002-11-01 00:00:00

abstract：:Polyamines are essential molecules supporting the structure, conformation, and function of nucleic acids and proteins. We studied stereoisomers of alpha,alpha'-dimethylated spermine [(R,R)-Me(2)Spm, (S,S)-Me(2)Spm, (R,S)-Me(2)Spm] for their ability to provoke DNA condensation and protect DNA from damage. (R,R)- and (R...

journal_title：Biomacromolecules

authors： Nayvelt I,Hyvönen MT,Alhonen L,Pandya I,Thomas T,Khomutov AR,Vepsäläinen J,Patel R,Keinänen TA,Thomas TJ

更新日期：2010-01-11 00:00:00

abstract：:A wool fiber sample was submitted to chemical-free steam explosion in view of potential exploitation of keratin-based industrial and farm wastes. Fiber keratin was converted into a dark-yellow sludge that was submitted to phase separation by filtration, centrifugation, and precipitation of the soluble materials from t...

journal_title：Biomacromolecules

authors： Tonin C,Zoccola M,Aluigi A,Varesano A,Montarsolo A,Vineis C,Zimbardi F

更新日期：2006-12-01 00:00:00

abstract：:Properties of Aloe vera galacturonate hydrogels formed via Ca(2+) crosslinking have been studied in regard to key parameters influencing gel formation including molecular weight, ionic strength, and molar ratio of Ca(2+) to COO(-) functionality. Dynamic oscillatory rheology and pulsed field gradient NMR (PFG-NMR) stud...

journal_title：Biomacromolecules

authors： McConaughy SD,Kirkland SE,Treat NJ,Stroud PA,McCormick CL

更新日期：2008-11-01 00:00:00

abstract：:Here we present time-resolved in situ transmission electron microscopy (TEM) observations and real-time manipulation of nematic ordered cellulose and ultradrawn polyethylene films. Drawn films of these two polymers exhibited a unique response to the low-dose electron beam. Electron beam damage was minimal based on ret...

journal_title：Biomacromolecules

authors： Brown RM Jr,Barnes Z,Sawatari C,Kondo T

更新日期：2007-01-01 00:00:00

abstract：:This paper describes the synthesis and evaluation of a series of multifunctional poly-l-glutamic acid derivatives that can be used as vectors for gene delivery. They readily form polyelectrolyte complexes with DNA, resulting in a reduced surface charge and size of the DNA. The formation of a polymer-DNA complex and th...

journal_title：Biomacromolecules

authors： Dubruel P,Dekie L,Schacht E

更新日期：2003-09-01 00:00:00

abstract：:Peak force infrared (PFIR) microscopy is a recently developed approach to acquire multiple chemical and physical material properties simultaneously and with nanometer resolution: topographical features, infrared (IR)-sensitive maps, adhesion, stiffness, and locally resolved IR spectra. This multifunctional mapping is ...

journal_title：Biomacromolecules

authors： Gusenbauer C,Jakob DS,Xu XG,Vezenov DV,Cabane É,Konnerth J

更新日期：2020-10-12 00:00:00

abstract：:We described the preparation of the glycol chitosan/heparin immobilized iron oxide nanoparticles (composite NPs) as a magnetic resonance imaging agent with a tumor-targeting characteristic. The iron oxide nanoseeds used clinically as a magnetic resonance imaging agent were immobilized into the glycol chitosan/heparin ...

journal_title：Biomacromolecules

authors： Yuk SH,Oh KS,Cho SH,Lee BS,Kim SY,Kwak BK,Kim K,Kwon IC

更新日期：2011-06-13 00:00:00

abstract：:Lignin is a natural, renewable biopolymer synthesized by plants. It is a macromolecule consisting of aromatic structures with high density of functional groups making it an ideal precursor for the design of sustainable biomaterials for applications such as drug delivery. The rational design of these materials requires...

journal_title：Biomacromolecules

authors： Salentinig S,Schubert M

更新日期：2017-08-14 00:00:00

abstract：:Inorganic polyphosphate (polyP) released by human platelets has recently been shown to activate blood clotting and identified as a potential target for the development of novel antithrombotics. Recent studies have shown that polymers with cationic binding groups (CBGs) inhibit polyP and attenuate thrombosis. However, ...

journal_title：Biomacromolecules

authors： Mafi A,Abbina S,Kalathottukaren MT,Morrissey JH,Haynes C,Kizhakkedathu JN,Pfaendtner J,Chou KC

更新日期：2018-04-09 00:00:00

abstract：:The use of polyelectrolyte surface-modified Cowpea mosaic virus (CPMV) for the templated synthesis of narrowly dispersed gold nanoparticles is described. The cationic polyelectrolyte, poly(allylamine) hydrochloride (PAH), is electrostatically bound to the external surface of the virus capsid; the polyelectrolyte promo...

journal_title：Biomacromolecules

authors： Aljabali AA,Lomonossoff GP,Evans DJ

更新日期：2011-07-11 00:00:00

abstract：:We investigate the effects of mixing a colloidal suspension of tunicate-derived cellulose nanocrystals (t-CNCs) with aqueous colloidal suspensions of two protein diblock copolymers, EC and CE, which bear two different self-assembling domains (SADs) derived from elastin (E) and the coiled-coil region of cartilage oligo...

journal_title：Biomacromolecules

authors： Haghpanah JS,Tu R,Da Silva S,Yan D,Mueller S,Weder C,Foster EJ,Sacui I,Gilman JW,Montclare JK

更新日期：2013-12-09 00:00:00

abstract：:A one-pot synthetic methodology for fabricating stimuli-responsive hemicellulose-based hydrogels was developed that consists of the in situ formation of magnetic iron oxide (Fe3O4) nanoparticles during the covalent cross-linking of O-acetyl-galactoglucomannan (AcGGM). The Fe3O4 nanoparticle content controlled the ther...

journal_title：Biomacromolecules

authors： Zhao W,Odelius K,Edlund U,Zhao C,Albertsson AC

更新日期：2015-08-10 00:00:00

abstract：:Intraneuronal aggregation of the intrinsically disordered protein α-synuclein is at the core of Parkinson's disease and related neurodegenerative disorders. Several reports show that the concentration of salts in the medium heavily affects its aggregation rate and fibril morphology, but a characterization of the indiv...

journal_title：Biomacromolecules

authors： Ramis R,Ortega-Castro J,Vilanova B,Adrover M,Frau J

更新日期：2020-12-14 00:00:00

abstract：:The fate of intravenously injected nanoparticles (NPs) is significantly affected by nano-protein interaction and corona formation. However, such an interaction between NPs and digestive enzymes occurring in the gastrointestinal tract (GIT) and its impacts on epithelial cell uptake are little known. We synthesized the ...

journal_title：Biomacromolecules

authors： Peng Q,Liu J,Zhang T,Zhang TX,Zhang CL,Mu H

更新日期：2019-04-08 00:00:00

abstract：:In this work, we report on an ATP-responsive low-molecular-weight polyethylenimine (LMW-PEI)-based supramolecular assembly. It formed via host-guest interaction between PEI (MW = 1.8 kDa)-α-cyclodextrin (α-CD) conjugates and PEI1.8k-phenylboronic acid (PBA) conjugates. The host-guest interaction between PEI1.8k-α-CD a...

journal_title：Biomacromolecules

authors： Jiang C,Qi Z,Jia H,Huang Y,Wang Y,Zhang W,Wu Z,Yang H,Liu J

更新日期：2019-01-14 00:00:00

abstract：:Angiogenesis has long been a desired therapeutic approach to improve clinical outcomes of conditions typified by ischemia. Vascular endothelial growth factor (VEGF) has demonstrated the ability to generate new blood vessels in vivo, but trials using intravenous delivery have not yet produced clinical success. Localize...

journal_title：Biomacromolecules

authors： Huang M,Vitharana SN,Peek LJ,Coop T,Berkland C

更新日期：2007-05-01 00:00:00

abstract：:Dynamic shear oscillation measurements at small strain were used to characterize the viscoelastic properties and related differences in the molecular structure of hydrogels based on gelatin methacrylamide. Gelatin was derivatized with methacrylamide side groups and was subsequently cross-linked by radical polymerizati...

journal_title：Biomacromolecules

authors： Van Den Bulcke AI,Bogdanov B,De Rooze N,Schacht EH,Cornelissen M,Berghmans H

更新日期：2000-04-01 00:00:00

abstract：:A series of chitosan/chitin samples with DA's varying between 5.2 and 89% was prepared from the reacetylation under soft conditions of a unique chitosan sample allowing the preservation of the chain distribution. The study of the variation of pH for the same concentration of amine groups, at different ionic strengths,...

journal_title：Biomacromolecules

authors： Sorlier P,Denuzière A,Viton C,Domard A

更新日期：2001-10-01 00:00:00

abstract：:Greener alternatives to synthetic polymers are constantly being investigated and sought after. Chitin is a natural polysaccharide that gives structural support to crustacean shells, insect exoskeletons, and fungal cell walls. Like cellulose, chitin resides in nanosized structural elements that can be isolated as nanof...

journal_title：Biomacromolecules

authors： Nawawi WMFBW,Jones M,Murphy RJ,Lee KY,Kontturi E,Bismarck A

更新日期：2020-01-13 00:00:00

abstract：:A lipid bilayer was deposited on a 3 μm diameter polystyrene (PS) bead via hydrophobic anchoring of bicelles containing oxyamine-bearing cholesteric moieties reacting with the aldehyde functionalized bead surface. Discoidal bicelles were formed by mixing dimyristoylphosphatidylcholine (DMPC), dihexanoylphosphatidylcho...

journal_title：Biomacromolecules

authors： Saleem Q,Zhang Z,Petretic A,Gradinaru CC,Macdonald PM

更新日期：2015-03-09 00:00:00

abstract：:Nanoparticles (NPs) composed of chitosan (CS) and poly(gamma-glutamic acid) (gamma-PGA) were prepared by a simple ionic-gelation method for oral insulin delivery. Fourier transform infrared (FT-IR) spectra indicated that CS and gamma-PGA were ionized at pH 2.5-6.6, while X-ray diffractograms demonstrated that the crys...

journal_title：Biomacromolecules

authors： Lin YH,Mi FL,Chen CT,Chang WC,Peng SF,Liang HF,Sung HW

更新日期：2007-01-01 00:00:00

abstract：:The morphologies of several ionotropic alginate hydrogels and aerogels were investigated by SAXS according to the nature of the divalent metal cation (Mn(2+), Co(2+), Zn(2+), Cu(2+)) and the guluronic fraction of the alginate. All alginate hydrogel and aerogel samples show isotropic small-angle X-ray scattering. Gelat...

journal_title：Biomacromolecules

authors： Agulhon P,Robitzer M,David L,Quignard F

更新日期：2012-01-09 00:00:00

abstract：:Nucleic acids have been engineered to participate in a wide variety of tasks. Among them, the enzyme-free amplification modes, enzyme-free DNA circuits (EFDCs), and hybridization chain reactions (HCRs) have been widely applied in a series of studies of bioanalysis. We demonstrated here an ultrasensitive hairpin probe-...

journal_title：Biomacromolecules

authors： Liao Y,Fu Y,Wu Y,Huang R,Zhou X,Xing D

更新日期：2015-11-09 00:00:00

abstract：:A novel methacrylate monomer containing a quinolone moiety was synthesized and homopolymerized in N,N-dimethylformamide (DMF) by using azobisisobutyronitrile (AIBN) as an initiator. The new monomer was copolymerized with poly(ethylene glycol) methyl ether methacrylate (MPEGMA) in DMF using the same initiator. The mono...

journal_title：Biomacromolecules

authors： Dizman B,Elasri MO,Mathias LJ

更新日期：2005-01-01 00:00:00