Antibacterial effects of green tea polyphenols on clinical isolates of methicillin-resistant Staphylococcus aureus.

Abstract:

:The antibacterial effects of tea polyphenols (TPP) extracted from Korean green tea (Camellia sinensis) against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) were evaluated. Characterization of the minimal inhibitory concentration (MIC) of oxacillin for 30 S. aureus strains isolated from patients treated with oxacillin identified 13 strains with an oxacillin MIC >or= 4 microg/mL as methicillin-resistant Staphylococcus aureus (MRSA) (range: 8 to 512 microg/mL), while 17 strains were methicillin-susceptible Staphylococcus aureus (MSSA) (range: 0.25-0.5 microg/mL). The MICs of TPP ranged from 50 to 180 microg/mL for both the MSSA and the MRSA strains. The MICs of oxacillin for each of the 13 MRSA strains were reduced between 8- and 128-fold when these strains were coincubated with sub-MIC (

journal_name

Curr Microbiol

journal_title

Current microbiology

authors

Cho YS,Schiller NL,Oh KH

doi

10.1007/s00284-008-9239-0

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

542-6

issue

6

eissn

0343-8651

issn

1432-0991

journal_volume

57

pub_type

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