Abstract:
:Interactions are the essence of all biomolecules because they cannot fulfill their roles without interacting with other molecules. Hence, mapping the interactions of biomolecules can be useful for understanding their roles and functions. Furthermore, the development of molecular based systems biology requires an understanding of the biomolecular interactions. In recent years, the mapping of protein-protein interactions in different species has been reported, but few reports have focused on the large-scale mapping of protein-protein interactions in human. Here, we review the developments in protein interaction mapping and we discuss issues and strategies for the mapping of the human protein interactome.
journal_name
Cell Resjournal_title
Cell researchauthors
Figeys Ddoi
10.1038/cr.2008.72subject
Has Abstractpub_date
2008-07-01 00:00:00pages
716-24issue
7eissn
1001-0602issn
1748-7838pii
cr200872journal_volume
18pub_type
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