Chemotherapeutic compounds and Acanthamoebae from eye infections.

Abstract:

:The amoebicidal and amoebistatic action in vitro of 24 compounds was tested on two strains of Acanthamoeba, A. polyphaga and A. castellanii, isolated from eye infections in this country. For comparison, the Ryan strain of A. castellanii and Naegleria gruberi L-1 were also examined. Nine compounds showed sufficient activity to merit further consideration, ie, acriflavine, proflavine, hydroxystilbamidine isethionate, paromomycin, miconazole, amphoterin, neomycin, polymyxin, and the last two combined in Neosporin.

journal_name

J Clin Pathol

authors

Nagington J,Richards JE

doi

10.1136/jcp.29.7.648

subject

Has Abstract

pub_date

1976-07-01 00:00:00

pages

648-51

issue

7

eissn

0021-9746

issn

1472-4146

journal_volume

29

pub_type

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