Abstract:
:Computational fluid dynamics (CFD) studies of airflow in a digital reference model of the 17-generation airway (bronchial tree) were accomplished using the FLUENT computational code, based on the anatomical model by Schmidt et al. [2004. A digital reference model of the human bronchial tree. Computerized Medical Imaging and Graphics 28, 203-211]. The lung model consists of 6.744 x 10(6) unstructured tetrahedral computational cells. A steady-state airflow rate of 28.3L/min was used to simulate the transient turbulent flow regime using a large eddy simulation (LES) turbulence model. This CFD mesh represents the anatomically realistic asymmetrical branching pattern of the larger airways. It is demonstrated that the nature of the secondary vortical flows, which develop in such asymmetric airways, varies with the specific anatomical characteristics of the branching conduits.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Gemci T,Ponyavin V,Chen Y,Chen H,Collins Rdoi
10.1016/j.jbiomech.2007.12.019subject
Has Abstractpub_date
2008-01-01 00:00:00pages
2047-54issue
9eissn
0021-9290issn
1873-2380pii
S0021-9290(07)00559-3journal_volume
41pub_type
杂志文章abstract::Porcine bioprosthesis were treated with 0.625% glutaraldehyde and stabilized under changing pressure from 4 to 30 mmHg. Bovine pericardium and 12 biovalves (of age between 14 days and 80 months) after implantation in the human body were investigated (7 porcine PB and 5 pericardial bioprosthesis--PCB). Circumferential ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90027-2
更新日期:1994-01-01 00:00:00
abstract::Mechanical strength along with high biocompatibility and water absorbing are among main characteristics of a desirable scaffold for cartilage tissue engineering. Having these properties, polyvinyl alcohol (PVA) can be a good option for constructing cartilage tissue engineering scaffolds. In this study, PVA hydrogel wa...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2019.109525
更新日期:2020-01-23 00:00:00
abstract::This article describes a method to simulate fusion of morselized cancellous bone. The morselized cancellous bone is mixed with an epoxy adhesive, in empirically determined proportions. The mixture is then impacted into a construct. When the epoxy cures, the morselized material fuses into a cohesive, contiguous structu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(01)00032-x
更新日期:2001-06-01 00:00:00
abstract::Cellular mechanics is known to play an important role in many cellular functions including adhesion, migration, proliferation, and differentiation. Human mesenchymal stem cells (hMSCs) demonstrate unique mechanical properties distinct from fully differentiated cells. This observation suggests that the stem cell mechan...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2011.07.024
更新日期:2011-10-13 00:00:00
abstract::Arteries in vivo are subjected to large longitudinal stretch, which changes significantly due to vascular disease and surgery. However, little is known about the effect of longitudinal stretch on arterial endothelium. The aim of this study was to determine the morphologic adaptation of arterial endothelial cells (ECs)...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.08.016
更新日期:2008-11-14 00:00:00
abstract::Several studies have attributed the prevalence of low back pain (LBP) in helicopter pilots mainly to poor posture in-flight and whole-body vibration, with the latter hypothesis particularly related to a cyclic response of the erector spine (ES) muscle to vibration. This work aims to determine if helicopter vibration a...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(01)00090-2
更新日期:2001-10-01 00:00:00
abstract::Tripping is responsible for a large percentage of falls. Minimum toe clearance (MTC) during the swing phase of gait is commonly used to infer the probability of tripping (POT). However, there is limited empirical evidence to support the relationship between these two variables, and other measures of toe trajectory may...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.10.045
更新日期:2016-12-08 00:00:00
abstract::The aim of this study was to evaluate if there are sex differences in postures of upper arm, upper back, head and neck after muscle fatigue induced by a simulated work task, requiring upper arm movements performed above shoulder level. Nineteen females and 18 males were evaluated. Upper arm elevation, upper back, head...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109855
更新日期:2020-06-23 00:00:00
abstract::Cultured cells subjected to fluid flow are exposed to mechanical forces and electrokinetic forces. The convective current establishes an electrokinetic force created by the flow-dependent transport of mobile ions in the media over the charged cell surfaces. This current can be expressed as a current density, the curre...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(96)84535-0
更新日期:1996-11-01 00:00:00
abstract::Tendon curvature plays a key role in mechanical gain (amplifying the joint excursion relative to fiber length change) during joint motion, but the mechanism remains unresolved. A three-dimensional finite element (FE) model was used to investigate the influence of intramuscular fiber orientation upon the curvature patt...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.09.014
更新日期:2016-10-03 00:00:00
abstract::Overdistension of the urinary bladder, secondary to outlet obstruction, causes cellular changes in the bladder wall, including hypertrophy of the smooth muscle cells, which increase bladder mass. To investigate the effects of increased mass on the cystometrogram (CMG), we have developed two mathematical models. In the...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:To test if the caudal acetabulum of the cat is unloaded at mid-stance as has been asserted. MATERIALS AND METHODS:A kinematic study of five healthy cats was performed to ascertain the mid-stance angle of the hip joint, and the orientation of the pelvis and femur. Femora and pelves from 10 feline cadavers wer...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.04.035
更新日期:2005-03-01 00:00:00
abstract::Pre-clinical tests are often performed to screen new implant designs, surgical techniques, and cement formulations. In this work, we developed a technique to simulate the cement-bone morphology found with postmortem retrieved cemented hip replacements. With this technique, a soy wax barrier is created along the endost...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.06.029
更新日期:2010-10-19 00:00:00
abstract::The three-dimensional trajectory of the body's centre of mass (COM) is useful to determine a number of biomechanical outcomes in running research. Previous studies have used the COM to calculate measures such as overstriding, vertical stiffness, and vertical oscillation. The COM is traditionally computed using the seg...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109886
更新日期:2020-07-17 00:00:00
abstract::Muscle activity has previously been suggested to minimize soft-tissue resonance which occurs at heel-strike during walking and running. If this concept were true then the greatest vibration damping would occur when the input force was closest to the resonant frequency of the soft-tissues at heel-strike. However, this ...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0021-9290(03)00216-1
更新日期:2003-12-01 00:00:00
abstract::This contribution is concerned with the modelling of PMMA-based bone cement polymerisation process and the associated heat effect. While existing models use description in terms of the so-called polymerisation fraction to fit the experimental data, the new model is constructed in such a way as to mimic the chemical pr...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.06.021
更新日期:2005-07-01 00:00:00
abstract::The objective of the current study was to use fluoroscopy to accurately determine the three-dimensional (3D), in vivo, weight-bearing kinematics of 10 normal and five anterior cruciate ligament deficient (ACLD) knees. Patient-specific bone models were derived from computed tomography (CT) data. 3D computer bone models...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章
doi:10.1016/j.jbiomech.2004.02.042
更新日期:2005-02-01 00:00:00
abstract::Linking human mechanical work to physiological work for the purpose of developing a model of physical fatigue is a complex problem that cannot be solved easily by conventional biomechanical analysis. The purpose of the study was to determine if two nonlinear analysis methods can address the fundamental issue of utiliz...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.06.011
更新日期:2009-09-18 00:00:00
abstract::It has been suspected that the mechanical environment in which a particular joint functions has an effect on the initiation or progression of degenerative joint disease. The objective of this study is to define the mechanical environment of the ankle joint, specifically, the contact areas and pressure distributions, t...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(83)90132-x
更新日期:1983-01-01 00:00:00
abstract::This study aimed to evaluate the sex difference in active muscle stiffness of the tibialis anterior muscle (TA) through shear modulus measurements performed using supersonic shear imaging (SSI) technique. Twenty-five women and twenty-one men participated in this study. Joint torque, electromyographic (EMG) activity an...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.08.008
更新日期:2016-10-03 00:00:00
abstract::We investigated the microstructural basis of a reduced stress concentration around the primary nutrient foramen of the equine third metacarpus. We quantified the spatial variations of compositional parameters (mineral content, volume fraction, histological architecture, and osteonal trajectories) from microradiographs...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(03)00130-1
更新日期:2003-10-01 00:00:00
abstract::We studied the mechanical and anatomical anisotropy of the canine diaphragmatic central tendon (CT). Dumb-bell-shaped strips with effective dimensions of 10 x 2 mm (length x width) were cut from different regions of the canine diaphragmatic CT in two different orientations relative to the direction of neighboring musc...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(91)90289-y
更新日期:1991-01-01 00:00:00
abstract::Sudden deceleration and frontal/rear impact configurations involve rapid movements that can cause spinal injuries. This study aimed to investigate the rotation rate effect on the L2-L3 motion segment load-sharing and to identify which spinal structure is at risk of failure and at what rotation velocity the failure may...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.03.036
更新日期:2009-06-19 00:00:00
abstract::Aim was to develop an in vivo technique which allows determination of femoro-tibial and of femoro-patellar 3D-kinematics in TKA simultaneously. The knees of 20 healthy volunteers and of eight patients with TKA (PCR, rotating platform) were investigated. Kinematics analysis was performed in an open MR-system at differe...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.03.020
更新日期:2007-01-01 00:00:00
abstract::Rigid body attitude and single-joint kinematics are typically expressed using three Cardan angles which represent rotations in anatomical planes. It was recently shown in the Biomechanics literature that Cardan angles inaccurately estimate true mean attitude due to an important mathematical inadequacy: attitude under-...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109976
更新日期:2020-10-09 00:00:00
abstract::An experimental study was carried out on asymmetrical abdominal aortic aneurysm (AAA) to analyse the physiological flows involved. Velocity measurements were performed using particle image velocimetry. Resting and exercise flow rates were investigated in models with rigid and compliant walls to assess the parameters a...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2006.11.017
更新日期:2007-01-01 00:00:00
abstract::To enhance the wearability of portable motion-monitoring devices, the size and number of sensors are minimized, but at the expense of quality and quantity of data collected. For example, owing to the size and weight of low-frequency force transducers, most currently available wearable gait measurement systems provide ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2018.01.046
更新日期:2018-04-11 00:00:00
abstract::Stiff-knee gait is characterized by diminished and delayed knee flexion during swing. Rectus femoris transfer surgery, a common treatment for stiff-knee gait, is often recommended when a patient exhibits prolonged activity of the rectus femoris muscle during swing. Treatment outcomes are inconsistent, in part, due to ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.05.030
更新日期:2008-08-07 00:00:00
abstract::The purpose of this study was to determine failure stresses and failure lengths of actively and passively stretched myofibrils. As expected, myofibrils failed at average sarcomere lengths (about 6-7μm) that vastly exceeded sarcomere lengths at which actin-myosin filament overlap ceases to exist (4μm) and thus actin-my...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.07.016
更新日期:2010-11-16 00:00:00
abstract::The objective of this work is to gain more insight into the processes of oral perception of food texture. Particularly, the limits for detectable thickness differences of objects, which are evaluated in the human mouth, are investigated. In a sensory study small, flexible circular disks (diameter in mm range) of varyi...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.04.012
更新日期:2007-01-01 00:00:00