Abstract：
:Pre-clinical tests are often performed to screen new implant designs, surgical techniques, and cement formulations. In this work, we developed a technique to simulate the cement-bone morphology found with postmortem retrieved cemented hip replacements. With this technique, a soy wax barrier is created along the endosteal surface of the bone, prior to cementing of the femoral component. This approach was applied to six fresh frozen human cadaver femora and the resulting cement-bone morphology and micromotion following application of torsional loads were measured on a transverse section of each bone. The contact fraction between cement and bone for the wax barrier specimens (6.4±5.7%, range: 0.5-15%) was similar to that found in postmortem retrievals (10.5±10.3%, range: 0.4-32.5%). Micro-motions at the cement-bone interface for the wax barrier specimens (0.5±1.06 mm, range: 0.005-2.66) were similar, but on average larger than those found with postmortem retrievals (0.092±0.22 mm, range: 0.002-0.73). The use of a wax barrier coating technique could improve experimental pre-clinical tests because it produces a cement-bone interface similar to those of functioning cemented components obtained following in vivo service.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Cherukuri AR,Miller MA,Race A,Izant TH,Mann KAdoi
10.1016/j.jbiomech.2010.06.029subject
Has Abstractpub_date
2010-10-19 00:00:00pages
2855-7issue
14eissn
0021-9290issn
1873-2380pii
S0021-9290(10)00365-9journal_volume
43pub_type
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