Abstract：
:Here I show that the mean codon usage bias of a genome, and of the lowly expressed genes in a genome, is largely similar across eukaryotes ranging from unicellular protists to vertebrates. Conversely, this bias in housekeeping genes and in highly expressed genes has a remarkable inverse relationship with species generation time that varies by more than four orders of magnitude. The relevance of these results to the nearly neutral theory of molecular evolution is discussed.
journal_name
Geneticsjournal_title
Geneticsauthors
Subramanian Sdoi
10.1534/genetics.107.086405subject
Has Abstractpub_date
2008-04-01 00:00:00pages
2429-32issue
4eissn
0016-6731issn
1943-2631pii
178/4/2429journal_volume
178pub_type
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