Among-environment heteroscedasticity and genetic autocorrelation: implications for the study of phenotypic plasticity.

abstract：:The murine dilute suppressor gene (dsu) suppresses the coat-color phenotype of three pigment mutations, dilute (d), ashen (ash) and leaden (ln), that each produce adendritic melanocytes. Suppression is due to the ability of dsu to partially restore (ash and ln), or almost completely restore (d), normal melanocyte morp...

journal_title：Genetics

authors： Moore KJ,Swing DA,Copeland NG,Jenkins NA

更新日期：1994-10-01 00:00:00

abstract：:Inactivation of the maternal or paternal X chromosome in a mammalian embryonic XX cell is believed to involve random choice between the two X's. We propose two alternative models. One suggests that choice is not random, while the other is consistent with random choice, but not one between two X's. ...

journal_title：Genetics

authors： Williams BR,Wu CT

更新日期：2004-07-01 00:00:00

abstract：:Gene silencing mediated by dsRNA (RNAi) can persist for multiple generations in Caenorhabditis elegans (termed RNAi inheritance). Here we describe the results of a forward genetic screen in C. elegans that has identified six factors required for RNAi inheritance: GLH-1/VASA, PUP-1/CDE-1, MORC-1, SET-32, and two novel ...

journal_title：Genetics

authors： Spracklin G,Fields B,Wan G,Becker D,Wallig A,Shukla A,Kennedy S

更新日期：2017-07-01 00:00:00

abstract：:Whole-mount fluorescence in situ hybridization (FISH) was applied to Arabidopsis thaliana seedlings to determine the three-dimensional (3D) interphase chromosome territory (CT) arrangement and heterochromatin location within the positional context of entire tissues or in particular cell types of morphologically well-p...

journal_title：Genetics

authors： Berr A,Schubert I

更新日期：2007-06-01 00:00:00

abstract：:In order to learn more about other proteins that may be involved in repression of HML and HMR in Saccharomyces cerevisiae, extragenic suppressor mutations were identified that could restore repression in cells defective in SIR4, a gene required for function of the silencer elements flanking HML and HMR. These suppress...

journal_title：Genetics

authors： Schnell R,D'Ari L,Foss M,Goodman D,Rine J

更新日期：1989-05-01 00:00:00

abstract：:In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can bring together beneficial alleles from different backgrounds, but tightly linked ...

journal_title：Genetics

authors： Weissman DB,Hallatschek O

更新日期：2014-04-01 00:00:00

abstract：:Cell differentiation in yeast species is controlled by a reversible, programmed DNA-rearrangement process called mating-type switching. Switching is achieved by two functionally similar but structurally distinct processes in the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe In ...

journal_title：Genetics

authors： Hanson SJ,Wolfe KH

更新日期：2017-05-01 00:00:00

abstract：:Adaptation in diploids is predicted to proceed via mutations that are at least partially dominant in fitness. Recently, we argued that many adaptive mutations might also be commonly overdominant in fitness. Natural (directional) selection acting on overdominant mutations should drive them into the population but then,...

journal_title：Genetics

authors： Sellis D,Kvitek DJ,Dunn B,Sherlock G,Petrov DA

更新日期：2016-07-01 00:00:00

abstract：:In lytic cycle crosses with Red-Gam-lambda phage, particles were examined that had undergone an Int-mediated exchange. It was assumed that this exchange dimerized the circular lambda, making it packageable. Among these Int-mediated recombinants, particles were identified that had, in addition, enjoyed a close double e...

journal_title：Genetics

authors： Stahl FW,Lieb M,Stahl MM

更新日期：1984-12-01 00:00:00

abstract：:Synthetics play an important role in quantitative genetic research and plant breeding, but few studies have investigated the application of genomic prediction (GP) to these populations. Synthetics are generated by intermating a small number of parents ([Formula: see text] and thereby possess unique genetic properties,...

journal_title：Genetics

authors： Schopp P,Müller D,Technow F,Melchinger AE

更新日期：2017-01-01 00:00:00

abstract：:We examine the influence of nonrandom mating and immigration on the evolutionary dynamics of cytonuclear associations in hybrid zones. Recursion equations for allelic and genotypic cytonuclear disequilibria were generated under models of (1) migration alone, assuming hybrid zone matings are random with respect to cyto...

journal_title：Genetics

authors： Asmussen MA,Arnold J,Avise JC

更新日期：1989-08-01 00:00:00

abstract：:Natural populations of Daphnia magna have been found which are polymorphic for electrophoretic variants of supernatant malic dehydrogenase, esterase, and alkaline phosphatase. Using these enzyme variants as genetic markers it has been possible to demonstrate the absence of recombination during parthenogenetic reproduc...

journal_title：Genetics

authors： Hebert PD,Ward RD

更新日期：1972-08-01 00:00:00

abstract：:We have analyzed the 2E1-3A1 area of the X chromosome with special attention to loci related to embryogenesis. Published maps indicate that this chromosomal segment contains ten bands. Our genetic analysis has identified 11 complementation groups: one recessive visible (prune), two female steriles and eight lethals. O...

journal_title：Genetics

authors： Perrimon N,Engstrom L,Mahowald AP

更新日期：1984-11-01 00:00:00

abstract：:The genetic basis of body weight in the mouse was investigated by measuring frequency changes of microsatellite marker alleles in lines divergently selected for body weight from a base population of a cross between two inbred strains. In several regions of the genome, sharp peaks of frequency change at linked markers ...

journal_title：Genetics

authors： Keightley PD,Hardge T,May L,Bulfield G

更新日期：1996-01-01 00:00:00

abstract：:An exact sampling formula for a Wright-Fisher population of fixed size N under the infinitely many neutral alleles model is deduced. This extends the Ewens formula for the configuration of a random sample to the case where the sample is drawn from a population of small size, that is, without the usual large-N and smal...

journal_title：Genetics

authors： Lessard S

更新日期：2007-10-01 00:00:00

abstract：:A previously employed method that uses the composition of noncoding DNA as the basis of a test for selection between synonymous codons in plastid genes is reevaluated. The test requires the assumption that in the absence of selective differences between synonymous codons the composition of silent sites in coding seque...

journal_title：Genetics

authors： Morton BR

更新日期：2001-09-01 00:00:00

abstract：:We have cloned and disrupted in vivo, by repeat-induced point mutations, the nuclear gene coding for an iron sulfur subunit of complex I from Neurospora crassa, homologue of the mammalian TYKY protein. Analysis of the obtained mutant nuo21.3c revealed that complex I fails to assemble. The peripheral arm of the enzyme ...

journal_title：Genetics

authors： Duarte M,Videira A

更新日期：2000-10-01 00:00:00

abstract：:The interval mapping method is widely used for the mapping of quantitative trait loci (QTLs) in segregating generations derived from crosses between inbred lines. The efficiency of detecting and the accuracy of mapping multiple QTLs by using genetic markers are much increased by employing multiple QTL models instead o...

journal_title：Genetics

authors： Jansen RC

更新日期：1993-09-01 00:00:00

abstract：:In finite populations, an allele disappears or reaches fixation due to two main forces, selection and drift. Selection is generally thought to accelerate the process: a selected mutation will reach fixation faster than a neutral one, and a disadvantageous one will quickly disappear from the population. We show that ev...

journal_title：Genetics

authors： Mafessoni F,Lachmann M

更新日期：2015-12-01 00:00:00

abstract：:Three previously described genes, enhancer of yellow, 1, 2 and 3, are shown to cooperate with the zeste gene in the control of white gene expression. The mutations e(y)1u1, e(y)3u1, and to a lesser extent e(y)2u1, enhance the effect of the zeste null allele zv77h. Different combinations of e(y)1u1, e(y)2u1 and e(y)3u1...

journal_title：Genetics

authors： Georgiev PG

更新日期：1994-11-01 00:00:00

abstract：:The breeding systems of many organisms are cryptic and difficult to investigate with observational data, yet they have profound effects on a species' ecology, evolution, and genome organization. Genomic approaches offer a novel, indirect way to investigate breeding systems, specifically by studying the transmission of...

journal_title：Genetics

authors： Svendsen N,Reisser CM,Dukić M,Thuillier V,Ségard A,Liautard-Haag C,Fasel D,Hürlimann E,Lenormand T,Galimov Y,Haag CR

更新日期：2015-11-01 00:00:00

abstract：:Crossover interference in meiosis is often modeled via stationary renewal processes. Here we consider a new model to incorporate the known biological feature of "obligate chiasma" whereby in most organisms each bivalent almost always has at least one crossover. The initial crossover is modeled as uniformly distributed...

journal_title：Genetics

authors： Falque M,Mercier R,Mézard C,de Vienne D,Martin OC

更新日期：2007-07-01 00:00:00

abstract：:Inbreeding depression, which refers to reduced fitness among offspring of related parents, has traditionally been studied using pedigrees. In practice, pedigree information is difficult to obtain, potentially unreliable, and rarely assessed for inbreeding arising from common ancestors who lived more than a few generat...

journal_title：Genetics

authors： Keller MC,Visscher PM,Goddard ME

更新日期：2011-09-01 00:00:00

abstract：:In many plant species, exposure to a prolonged period of cold during the winter promotes flowering in the spring, a process termed vernalization. In Arabidopsis thaliana, the vernalization requirement of winter-annual ecotypes is caused by the MADS-box gene FLOWERING LOCUS C (FLC), which is a repressor of flowering. D...

journal_title：Genetics

authors： Reeves PA,He Y,Schmitz RJ,Amasino RM,Panella LW,Richards CM

更新日期：2007-05-01 00:00:00

abstract：:Genetic control over chromosome stability in the interspecific hybrid embryos of Hordeum vulgare and H. bulbosum has been hypothesized to reside on specific chromosomes. In this study, crosses between the primary trisomic lines for the seven different H. vulgare chromosomes and tetraploid H. bulbosum revealed that bot...

journal_title：Genetics

authors： Ho KM,Kasha KJ

更新日期：1975-10-01 00:00:00

abstract：:Paramecium has long been a model eukaryote. The sequence of the Paramecium tetraurelia genome reveals a history of three successive whole-genome duplications (WGDs), and the sequences of P. biaurelia and P. sexaurelia suggest that these WGDs are shared by all members of the aurelia species complex. Here, we present th...

journal_title：Genetics

authors： McGrath CL,Gout JF,Doak TG,Yanagi A,Lynch M

更新日期：2014-08-01 00:00:00

abstract：:A large offspring-number diploid biparental multilocus population model of Moran type is our object of study. At each time step, a pair of diploid individuals drawn uniformly at random contributes offspring to the population. The number of offspring can be large relative to the total population size. Similar "heavily ...

journal_title：Genetics

authors： Birkner M,Blath J,Eldon B

更新日期：2013-01-01 00:00:00

abstract：:Our previous work suggests that the Nhp6 HMGB protein stimulates RNA polymerase II transcription via the TATA-binding protein TBP and that Nhp6 functions in the same functional pathway as the Gcn5 histone acetyltransferase. In this report we examine the genetic relationship between Nhp6 and Gcn5 with the Mot1 and Ccr4...

journal_title：Genetics

authors： Biswas D,Yu Y,Mitra D,Stillman DJ

更新日期：2006-02-01 00:00:00

abstract：:Metazoan genomes encode an abundant collection of mRNA-like, long noncoding (lnc)RNAs. Although lncRNAs greatly expand the transcriptional repertoire, we have a limited understanding of how these RNAs contribute to developmental regulation. Here, we investigate the function of the Drosophila lncRNA called yellow-achae...

journal_title：Genetics

authors： Soshnev AA,Ishimoto H,McAllister BF,Li X,Wehling MD,Kitamoto T,Geyer PK

更新日期：2011-10-01 00:00:00

abstract：:A long-standing prediction in evolutionary biology is that organisms experience a so-called "cost of complexity" manifested as a decreasing rate of adaptation in populations as organisms or selective environments become increasingly complex. This theory assumes the ubiquity of antagonistic pleiotropy, or trade-offs in...

journal_title：Genetics

authors： Sackman AM,Rokyta DR

更新日期：2019-05-01 00:00:00