Comparison of the contributions of heat-labile enterotoxin and heat-stable enterotoxin b to the virulence of enterotoxigenic Escherichia coli in F4ac receptor-positive young pigs.

abstract：:Immunity to pneumococcal colonization in mice by exposure to live or killed pneumococci has been shown to be antibody independent but dependent on CD4+ T cells. Here we show that intranasal immunization with pneumococcal proteins (pneumococcal surface protein C, adhesin A, and a pneumolysoid) can elicit a similar mech...

journal_title：Infection and immunity

authors： Basset A,Thompson CM,Hollingshead SK,Briles DE,Ades EW,Lipsitch M,Malley R

更新日期：2007-11-01 00:00:00

abstract：:Hydroxystilbamidine (HSB) is a potent suppressor of the plaque-forming cell response of mice injected with heterologous erythrocytes. HSB, given in varying doses and injection schedules, suppressed both the primary and secondary immune responses to bovine serum albumin. Apparently the effect is not simply a toxic effe...

journal_title：Infection and immunity

authors： Folds JD,Orlando G,Spitznagel JK

更新日期：1975-03-01 00:00:00

abstract：:The enteric pathogen Shigella is one of the leading causes of moderate-to-severe diarrhea and death in young children in developing countries. Transformed cell lines and animal models have been widely used to study Shigella pathogenesis. In addition to altered physiology, transformed cell lines are composed of a singl...

journal_title：Infection and immunity

authors： Ranganathan S,Doucet M,Grassel CL,Delaine-Elias B,Zachos NC,Barry EM

更新日期：2019-03-25 00:00:00

abstract：:Porphyromonas gingivalis, a gram-negative anaerobic bacterium associated with active lesions of chronic periodontitis, produces several proteinases which are presumably involved in host colonization, perturbation of the immune system, and tissue destruction. The aims of this study were to investigate the degradation o...

journal_title：Infection and immunity

authors： Goulet V,Britigan B,Nakayama K,Grenier D

更新日期：2004-08-01 00:00:00

abstract：:We have focused on regions of staphylococcal enterotoxin C1 (SEC1) causing immunomodulation. N-terminal deletion mutants lacking residues 6 through 13 induced T-cell proliferation similar to that induced by native toxin. However, mutants with residues deleted between positions 19 and 33, although nonmitogenic themselv...

journal_title：Infection and immunity

authors： Hoffmann ML,Jablonski LM,Crum KK,Hackett SP,Chi YI,Stauffacher CV,Stevens DL,Bohach GA

更新日期：1994-08-01 00:00:00

abstract：:Oxygenated fatty acids, or oxylipins, play an essential role in physiological signaling and developmental processes in animals, plants, and fungi. Previous characterization of three Aspergillus fumigatus dioxygenases (PpoA, PpoB, and PpoC), similar in sequence to mammalian cyclooxygenases, showed that PpoA is responsi...

journal_title：Infection and immunity

authors： Dagenais TR,Chung D,Giles SS,Hull CM,Andes D,Keller NP

更新日期：2008-07-01 00:00:00

abstract：:Mycobacterium leprae are killed by myeloperoxidase (or eosinophil peroxidase), H2O2, and a halide, thus suggesting a mechanism for their destruction by peroxidase-containing phagocytes. ...

journal_title：Infection and immunity

authors： Klebanoff SJ,Shepard CC

更新日期：1984-05-01 00:00:00

abstract：:In a cross-sectional survey of 187 Gambian children and adults, we have analyzed prevalence, fine specificity, and 19-kilodalton merozoite surface protein 1 (MSP-1(19))-specific erythrocyte invasion inhibitory activity of antibodies to MSP-1(19) but find no significant association between any of these parameters and p...

journal_title：Infection and immunity

authors： Corran PH,O'Donnell RA,Todd J,Uthaipibull C,Holder AA,Crabb BS,Riley EM

更新日期：2004-10-01 00:00:00

abstract：:Attachment of Mycobacterium avium subsp. paratuberculosis to host tissue and penetration of mucosal surfaces are pivotal events in the pathogenesis of Johne's disease. Fibronectin (FN) binding is required for attachment and internalization of several mycobacteria by epithelial cells in vitro. The objective of this stu...

journal_title：Infection and immunity

authors： Secott TE,Lin TL,Wu CC

更新日期：2001-04-01 00:00:00

abstract：:[1-(14)C]acetate is incorporated into lipids more rapidly by liver from Aeromonas salmonicida-infected trout than by normal trout liver, both in vitro and in vivo. The increase was, in general, about twofold to less than threefold. ...

journal_title：Infection and immunity

authors： Shieh HS

更新日期：1976-09-01 00:00:00

abstract：:Anti-rabbit alveolar macrophage goat serum (AMS), adsorbed of hemolysins and hemagglutinins, exhibited complement-dependent cytotoxicity for the following rabbit target cells: alveolar macrophages, thymocytes, and kidney (RK-13) cells. The intravenous injection of AMS, sufficient to reduce markedly the dermal tubercul...

journal_title：Infection and immunity

authors： Moore VL,Myrvik QN

更新日期：1970-12-01 00:00:00

abstract：:Antimicrobial peptides, such as defensins or cathelicidins, are effector substances of the innate immune system and are thought to have antimicrobial properties that contribute to host defense. The evidence that vertebrate antimicrobial peptides contribute to innate immunity in vivo is based on their expression patter...

journal_title：Infection and immunity

authors： Bals R,Weiner DJ,Moscioni AD,Meegalla RL,Wilson JM

更新日期：1999-11-01 00:00:00

abstract：:Interaction of bacteria with mucosal surfaces can modulate the production of proinflammatory cytokines and adhesion molecules produced by epithelial cells. Previously, we showed that expression of interleukin-8 (IL-8) and intercellular adhesion molecule 1 (ICAM-1) by gingival epithelial cells increases following inter...

journal_title：Infection and immunity

authors： Huang GT,Kim D,Lee JK,Kuramitsu HK,Haake SK

更新日期：2001-03-01 00:00:00

abstract：:Severe pediatric malaria is an important risk factor for developing disseminated infections with nontyphoidal Salmonella serotypes (NTS). While recent animal studies on this subject are lacking, early work suggests that an increased risk for developing systemic NTS infection during malaria is caused by hemolytic anemi...

journal_title：Infection and immunity

authors： Roux CM,Butler BP,Chau JY,Paixao TA,Cheung KW,Santos RL,Luckhart S,Tsolis RM

更新日期：2010-04-01 00:00:00

abstract：:Pathogenicity of Rickettsia tsutsugamushi for laboratory mice is known to be influenced by at least three factors: (i) route of inoculation, (ii) antigenic strain, and (iii) natural resistance of the host. By using Karp, Gilliam, and Kato strains of R. tsutsugamushi, we examined the effect of these three pathogenicity...

journal_title：Infection and immunity

authors： Groves MG,Kelly DJ

更新日期：1989-05-01 00:00:00

abstract：:Development of hemolytic uremic syndrome (HUS) after infection by Shigella dysenteriae 1 or enterohemorrhagic Escherichia coli has been associated with the production of Shiga toxins (verotoxins). The putative target of Shiga toxins in HUS is the renal microvascular endothelium. This report shows that preincubation of...

journal_title：Infection and immunity

authors： Kaye SA,Louise CB,Boyd B,Lingwood CA,Obrig TG

更新日期：1993-09-01 00:00:00

abstract：:Immunoglobulin M antibody to hepatitis A virus (IgM anti-HAV) is found in most patients with acute type A hepatitis. To determine the duration of this IgM response as well as to confirm that IgM anti-HAV is a specific marker for acute infection, we developed a solid-phase radioimmunoassay for IgM anti-HAV. This new as...

journal_title：Infection and immunity

authors： Lemon SM,Brown CD,Brooks DS,Simms TE,Bancroft WH

更新日期：1980-06-01 00:00:00

abstract：:Attachment of Fusobacterium nucleatum to various oral surfaces is mediated by several adhesins anchored on its outer surface. Monoclonal antibodies (MAbs) were prepared and used to identify the putative galactose-binding adhesin of F. nucleatum PK1594. Four unique MAbs, 8G7, 26B9, 28G11, and 29D4, were isolated on the...

journal_title：Infection and immunity

authors： Shaniztki B,Hurwitz D,Smorodinsky N,Ganeshkumar N,Weiss EI

更新日期：1997-12-01 00:00:00

abstract：:A major ceramide monohexoside (CMH) was purified from lipidic extracts of Cryptococcus neoformans. This molecule was analyzed by high-performance thin-layer chromatography (HPTLC), gas chromatography coupled with mass spectrometry, and fast atom bombardment-mass spectrometry. The cryptococcal CMH is a beta-glucosylcer...

journal_title：Infection and immunity

authors： Rodrigues ML,Travassos LR,Miranda KR,Franzen AJ,Rozental S,de Souza W,Alviano CS,Barreto-Bergter E

更新日期：2000-12-01 00:00:00

abstract：:The Lyme disease spirochete, Borrelia burgdorferi, exists in a zoonotic cycle involving an arthropod tick and mammalian host. Dissemination of the organism within and between these hosts depends upon the spirochete's ability to traverse through complex tissues. Additionally, the spirochete outruns the host immune cell...

journal_title：Infection and immunity

authors： Sultan SZ,Manne A,Stewart PE,Bestor A,Rosa PA,Charon NW,Motaleb MA

更新日期：2013-06-01 00:00:00

abstract：:Three types of caseinolytic proteases (Pase-A, Pase-B, and Pase-C) were isolated and purified from culture supernatants of Porphyromonas gingivalis 381 by the combined procedures of acetone precipitation, gel filtration, solubilization with octylthioglucoside followed by affinity chromatography on arginine-Sepharose 4...

journal_title：Infection and immunity

authors： Hinode D,Hayashi H,Nakamura R

更新日期：1991-09-01 00:00:00

abstract：:Listeria monocytogenes is an intracellular bacterial pathogen which causes bacteremia and has a tropism for the central nervous system and a propensity to cause maternofetal infection. L. monocytogenes has been shown to be an effective prophylactic and a therapeutic vaccine vector for viral and tumor antigens in anima...

journal_title：Infection and immunity

authors： Angelakopoulos H,Loock K,Sisul DM,Jensen ER,Miller JF,Hohmann EL

更新日期：2002-07-01 00:00:00

abstract：:Staphylococcus aureus and Salmonella enterica serovar Dublin invade osteoblasts and are causative agents of human bone disease. In the present study, we examined the ability of S. aureus and Salmonella serovar Dublin to induce the production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by normal ...

journal_title：Infection and immunity

authors： Alexander EH,Bento JL,Hughes FM Jr,Marriott I,Hudson MC,Bost KL

更新日期：2001-03-01 00:00:00

abstract：:A protein antigen called TR-o was isolated from supernatant of a sonically treated Reiter treponeme. The isolation procedure included anion-exchange chromatography on Whatman DE-52, hydrophobic interaction chromatography on decyl agarose, and finally gel filtration on Ac-A-22 Ultrogel. The fractionations were monitore...

journal_title：Infection and immunity

authors： Petersen CS,Pedersen NS,Axelsen NH

更新日期：1982-03-01 00:00:00

abstract：:The 120-kDa rickettsial outer membrane protein (rOmpB) is encoded by a gene with the capacity to encode a protein of approximately 168 kDa. The carboxy-terminal end of the molecule is apparently cleaved to yield 120- and 32-kDa products. Both polypeptides are surface exposed and remain associated with the outer membra...

journal_title：Infection and immunity

authors： Hackstadt T,Messer R,Cieplak W,Peacock MG

更新日期：1992-01-01 00:00:00

abstract：:A virus, 78-238, isolated from the cerebrospinal fluid of a dog with neurological dysfunction, was characterized as a paramyxovirus. This conclusion was supported by viral cytopathic effects and morphological appearance of virions and nucleocapsids in infected cells. Nucleocapsids were found in the cytoplasm of all in...

journal_title：Infection and immunity

authors： Baumgärtner WK,Metzler AE,Krakowka S,Koestner A

更新日期：1981-03-01 00:00:00

abstract：:The obligate intracellular parasite Toxoplasma gondii can actively infect any nucleated cell type, including cells from the immune system. The rapid transfer of T. gondii from infected dendritic cells to effector natural killer (NK) cells may contribute to the parasite's sequestration and shielding from immune recogni...

journal_title：Infection and immunity

authors： Sultana MA,Du A,Carow B,Angbjär CM,Weidner JM,Kanatani S,Fuks JM,Muliaditan T,James J,Mansfield IO,Campbell TM,Liu L,Kadri N,Lambert H,Barragan A,Chambers BJ

更新日期：2017-09-20 00:00:00

abstract：:A chimeric recombinant protein composed of the lktA gene product from Pasteurella haemolytica fused to bovine interleukin-2 (IL-2) was made. The LKT-IL-2 chimera was compared with recombinant bovine IL-2 with regard to the ability to induce proliferative responses and LAK cell activity in bovine peripheral blood monon...

journal_title：Infection and immunity

authors： Hughes HP,Campos M,Potter AA,Babiuk LA

更新日期：1992-02-01 00:00:00

abstract：:The cell surface hydrophobicity of 10 pigmented and 4 nonpigmented clinical Serratia marcescens strains was studied, based on the ability of the strains to adhere to hydrocarbons and to polystyrene. The cell surface hydrophobicity depended greatly on growth temperature; all of the strains tested were adherent followin...

journal_title：Infection and immunity

authors： Rosenberg M,Blumberger Y,Judes H,Bar-Ness R,Rubinstein E,Mazor Y

更新日期：1986-03-01 00:00:00

abstract：:The role of a plasmid in the virulence activity of an enteropathogenic Escherichia coli (EPEC) strain belonging to serotype 0111:NM was examined. EPEC strain B171, which is resistant to chloramphenicol, streptomycin, sulfathiazole, and tetracycline, harbors a 54-megadalton plasmid, pYR111, and exhibits localized adher...

journal_title：Infection and immunity

authors： Riley LW,Junio LN,Libaek LB,Schoolnik GK

更新日期：1987-09-01 00:00:00