The voice of the patients: allergic rhinitis is not a trivial disease.

abstract：PURPOSE OF REVIEW:Cow's milk allergy affects 2-3% of young children, the economic impact of which necessitates search for simple diagnostic tools and affordable milk substitutes. This review examines recent studies on the diagnosis of cow's milk allergy as well as on the allergenicity of milk from other mammalian speci...

journal_title：Current opinion in allergy and clinical immunology

authors： Järvinen KM,Chatchatee P

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Food allergy has emerged as a significant health problem. Peanut allergy is a major cause of food-induced fatal and near fatal anaphylactic reactions, and the incidence in children is increasing. Attempts to manage peanut allergy by strict avoidance are often unsuccessful. The purpose of this review i...

journal_title：Current opinion in allergy and clinical immunology

authors： Li XM

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace. RECENT FINDINGS:Increased recruitment and infiltration of ne...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi Y,Lee Y,Park HS

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The main feature of allergen-specific immunotherapy is its capacity to modify the natural history of the disease, reducing the development of asthma and new sensitizations after 3-4 years of treatment. For this reason, adherence to the therapy is mandatory, as happens for all chronic medical treatment...

journal_title：Current opinion in allergy and clinical immunology

authors： Senna G,Ridolo E,Calderon M,Lombardi C,Canonica GW,Passalacqua G

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cough is one of the defining symptoms of asthma, wheeze, chest tightness and breathlessness have generally received more attention. The impact of coughing for patients may be more important than currently appreciated and has been rated more troublesome than wheeze, chest tightness or disturba...

journal_title：Current opinion in allergy and clinical immunology

authors： Smith JA

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze recent findings on antibiotic hypersensitivity reactions in children focusing on betalactams, with regard to clinical entities, antibiotics involved and diagnostic methods. RECENT FINDINGS:Betalactams are the most frequent cause of antibiotic hypersensitivity, more specifically amoxicillin...

journal_title：Current opinion in allergy and clinical immunology

authors： Fernandez TD,Mayorga C,Ariza A,Corzo JL,Torres MJ

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Targeting allergens to surface receptors on antigen presenting cells may provide a therapeutic strategy for allergic disease. This article discusses the immunomodulatory capacity of a molecule (H22-Fel d 1), which targets the major cat allergen, Fel d 1, to the high affinity IgG receptor, Fc gammaRI, ...

journal_title：Current opinion in allergy and clinical immunology

authors： Hulse KE,Woodfolk JA

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes current knowledge regarding the control of human mast cell and basophil signaling and recent developments using a new therapeutic platform consisting of a human bifunctional gamma and epsilon heavy chain (Fc gamma-Fc epsilon) protein to inhibit allergic reactivity. RECENT FINDI...

journal_title：Current opinion in allergy and clinical immunology

authors： Saxon A,Zhu D,Zhang K,Allen LC,Kepley CL

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review and discuss recent studies on component-resolved diagnostics in food allergy, involving panels of pure allergen molecules or arrays of peptides derived from allergen sequences, and to summarize the reporting of new food allergens during the past 2 years. RECENT ...

journal_title：Current opinion in allergy and clinical immunology

authors： Lidholm J,Ballmer-Weber BK,Mari A,Vieths S

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The phenomenon of intrinsic or nonatopic asthma continues to raise questions about the possible role of IgE-mediated mechanisms in asthma pathogenesis. With the current availability of anti-IgE therapy for asthma, clarification of this issue has never been more timely and relevant. RECENT FINDINGS:Th...

journal_title：Current opinion in allergy and clinical immunology

authors： Corrigan C

更新日期：2004-02-01 00:00:00

abstract：:Ocular allergy presents unsolved mysteries in molecular and cellular mechanisms, and at the same time continues to challenge ophthalmologists daily in a wide array of disease forms. The recent understanding of the key role of the T helper type 2 cytokines, adhesion molecules and chemokines may provide future avenues f...

journal_title：Current opinion in allergy and clinical immunology

authors： Solomon A,Pe'er J,Levi-Schaffer F

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to compare and contrast the newer inhaled corticosteroid (ICS) ciclesonide with older ICSs in terms of pharmacodynamic and pharmacokinetic properties and how these affect comparative efficacy. In addition, clinical dosing strategies for ICSs including as-needed use will b...

journal_title：Current opinion in allergy and clinical immunology

authors： Stoloff SW,Kelly HW

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:In the US anterior ocular inflammatory disease (AOID) composed of the spectrum of ocular allergies, different forms of infectious conjunctivitis, and dry eye diseases, affects over 40% of the population. This review evaluates the current economic costs for AOID associated pharmacotherapies. RECENT FI...

journal_title：Current opinion in allergy and clinical immunology

authors： Khan RS,Rizvi S,Syed BA,Bielory L

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenic mechanisms underlying the correlation between ocular allergy and dry eye disease (DED), highlighting how the first condition may be a risk factor for the second one. RECENT FINDINGS:Recent advances in our comprehension of the pathogenesis of ocular allergy and...

journal_title：Current opinion in allergy and clinical immunology

authors： Villani E,Rabbiolo G,Nucci P

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need to discontinue the use of contact lenses. This review presents the ...

journal_title：Current opinion in allergy and clinical immunology

authors： Solomon A

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To familiarize the reader with the recent developments in the identification of food protein allergens by proteomics mass spectrometry-based methods, named allergenomics. RECENT FINDINGS:The proteomic analysis of food protein allergens has became a hot topic in the food safety field in recent years. ...

journal_title：Current opinion in allergy and clinical immunology

authors： Di Girolamo F,Muraca M,Mazzina O,Lante I,Dahdah L

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Mastocytosis is a rare disease characterized by increased mast cells in skin and/or internal organs. We evaluate the impact of mastocytosis on diagnosis and treatment of Hymenoptera venom allergy. RECENT FINDINGS:Patients with Hymenoptera venom allergy who suffer from mastocytosis develop life-threat...

journal_title：Current opinion in allergy and clinical immunology

authors： Ruëff F,Placzek M,Przybilla B

更新日期：2006-08-01 00:00:00

abstract：:Asthma is a disease that is, in large part, defined by abnormalities of pulmonary function. Failure of any new treatment modality to improve objective measures of lung function suggests a limited usefulness of such new therapies. The clear dissociation between inflammation and airways responsiveness indicates the latt...

journal_title：Current opinion in allergy and clinical immunology

authors： Kaminsky DA,Irvin CG

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Ocular allergy is often encountered by allergists, ophthalmologists, pediatricians, and primary care physicians. An understanding of the immunologic mechanisms, the differential diagnosis, the clinical features, and the treatment of ocular allergy will be useful to all physicians who encounter these p...

journal_title：Current opinion in allergy and clinical immunology

authors： Friedlaender MH

更新日期：2011-10-01 00:00:00

abstract：:A number of recent cohort and cross-sectional studies have contributed substantial knowledge to factors that influence the early development of asthma. Here, we summarize the recent evidence for the role of early life events such as prenatal factors, infections, diet and allergen exposure, and discuss the implications...

journal_title：Current opinion in allergy and clinical immunology

authors： Peat JK,Mellis CM

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the recent insights into the definition, causes, natural outcome, and key elements of irritant-induced asthma (IIA) management. RECENT FINDINGS:IIA is a subtype of occupational asthma without immunologic sensitization and includes the typical reactive airway dysfunction syndrome (RADS) an...

journal_title：Current opinion in allergy and clinical immunology

authors： Labrecque M

更新日期：2012-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the immunology of chronic beryllium disease. It addresses the importance of the interaction between class II molecules and the T cells that recognize beryllium, along with the subsequent immune response that results in sensitization and disease, and genetic factors leading to var...

journal_title：Current opinion in allergy and clinical immunology

authors： Samuel G,Maier LA

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Dry eye disease (DED) is a complex, multifactorial condition that is challenging to diagnose and monitor clinically. To date, diagnosis has consisted largely of self-reported symptom questionnaires and a collection of clinical tests including vital dye staining, estimation of tear breakup time and Sch...

journal_title：Current opinion in allergy and clinical immunology

authors： Dohlman TH,Ciralsky JB,Lai EC

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases represent a growing global health concern, especially among pediatric populations. Current strategies for the treatment of allergies and asthma focus on limiting the severity of the symptoms; however, additional research investigating the mechanisms promoting inflammation in the cont...

journal_title：Current opinion in allergy and clinical immunology

authors： Inclan-Rico JM,Ponessa JJ,Siracusa MC

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to recap recent published data on immunological mechanisms underlying sublingual immunotherapy (SLIT). RECENT FINDINGS:Although several alternative noninvasive allergen application strategies have been investigated in allergen-specific immunotherapy, local intraoral allergen applicat...

journal_title：Current opinion in allergy and clinical immunology

authors： Allam JP,Novak N

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe adverse drug reactions. Once thought to be idiosyncratic and unpredictable, there has been significant progress made in the understanding of the pathomechanism and pharmacogenetics of such reactions. These ...

journal_title：Current opinion in allergy and clinical immunology

authors： Lee HY,Chung WH

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:As drug allergy research aims to inform clinical practice, implementation of best practices may be influenced by financial resources required to incorporate new interventions and the resulting clinical and economic returns on those resource investments. The present review summarizes new insights into ...

journal_title：Current opinion in allergy and clinical immunology

authors： Mattingly TJ 2nd

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the association between the common dominantly inherited genetic trait hereditary alpha-tryptasemia (HαT) and hymenoptera venom-induced anaphylaxis (HVA). RECENT FINDINGS:Elevated BST has been correlated with more severe systemic anaphylaxis in humans in a number of settings - most notably ...

journal_title：Current opinion in allergy and clinical immunology

authors： O'Connell MP,Lyons JJ

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Many interventions have been undertaken in managing asthma in a population-based framework. The identification of successful interventions would guide policy implementation to improve outcomes in patient morbidity and mortality and healthcare costs. RECENT FINDINGS:Several studies have focussed on em...

journal_title：Current opinion in allergy and clinical immunology

authors： McNairn JD,Ramos C,Portnoy JM

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the recent evidence on the effect of cleaning jobs on asthma, based on case reports and series of occupational asthma among cleaners, and epidemiological studies on the relationship between different characteristics of cleaning and asthma risk, as well as to ...

journal_title：Current opinion in allergy and clinical immunology

authors： Jaakkola JJ,Jaakkola MS

更新日期：2006-04-01 00:00:00