Allergen uptake and presentation by dendritic cells.

abstract：PURPOSE OF REVIEW:To remind readers that evaporative water loss from the airway surface is the stimulus for exercise-induced bronchoconstriction. To emphasize that recruitment of the peripheral airways determines severity of exercise-induced bronchoconstriction. To draw attention to the potential for injury of the epit...

journal_title：Current opinion in allergy and clinical immunology

authors： Anderson SD

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To present and discuss the rationale for using high-dose intravenous human immunoglobulins in the treatment of severe drug eruptions and the clinical results of recently published series. RECENT FINDINGS:In toxic epidermal necrolysis, intravenous human immunoglobulins were expected to inhibit the apo...

journal_title：Current opinion in allergy and clinical immunology

authors： Bachot N,Roujeau JC

更新日期：2003-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe the impact of asthma treatment non-adherence on patients and the healthcare system, and to outline areas of responsibility towards improved adherence. RECENT FINDINGS:The average cost of healthcare expenses for each person in the United States in 2002 was 544...

journal_title：Current opinion in allergy and clinical immunology

authors： Bender BG,Rand C

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Current understanding of the role of oxidative stress in airway inflammation suggests that antioxidant therapy may be important to optimize the treatment. This review summarizes recent investigations of novel antioxidant agents for upper airway inflammation, with selected studies focused on lower airw...

journal_title：Current opinion in allergy and clinical immunology

authors： Braskett M,Riedl MA

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective immediate reactions to NSAIDs imply that patients develop a urticarial/anaphylactic response to a single drug with good tolerance to other compounds. No systematic review of these reactions has yet been made. RECENT FINDINGS:With the increase in consumption of NSAIDs, these have become one ...

journal_title：Current opinion in allergy and clinical immunology

authors： Canto MG,Andreu I,Fernandez J,Blanca M

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent findings on the skin microbiome. It provides an update on the current understanding of the role of microbiota in healthy skin and in inflammatory and allergic skin diseases. RECENT FINDINGS:Advances in computing and high-throughput sequencing technology have enabled in-dep...

journal_title：Current opinion in allergy and clinical immunology

authors： Zeeuwen PL,Kleerebezem M,Timmerman HM,Schalkwijk J

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence for adverse respiratory effects of occupational exposure to disinfectants and cleaning products (DCPs) has grown in the last two decades. The relationship between DCPs and asthma is well documented but questions remain regarding specific causal agents. Beyond asthma, associations between DCPs...

journal_title：Current opinion in allergy and clinical immunology

authors： Dumas O

更新日期：2020-12-05 00:00:00

abstract：PURPOSE OF REVIEW:Key aspects and outcomes from the recently published guidance on the regulation of allergen products are summarized. RECENT FINDINGS:A new regulatory guideline has been published to enhance harmonized national approaches on the regulation of allergen products and thereby strengthen the availability o...

journal_title：Current opinion in allergy and clinical immunology

authors： Bonertz A,Mahler V,Vieths S

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to describe the role of precision medicine in the diagnosis, treatment, and monitoring of cow's milk allergy. RECENT FINDINGS:The development of 'omics' sciences in the field of food allergy has led to a better understanding of the allergenicity of cow's milk proteins and si...

journal_title：Current opinion in allergy and clinical immunology

authors： D'Auria E,Venter C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergen immunotherapy (AIT) is still the only causal treatment for allergic rhinitis and asthma. However, conventional subcutaneous AIT administration schedules are time-consuming and safety issues still play a role; for sublingual AIT, the best efficacy is still investigated and for food allergy the...

journal_title：Current opinion in allergy and clinical immunology

authors： Larenas-Linnemann D

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the data of both preclinical studies and initial clinical trials of a novel allergoid for allergen specific immunotherapy. This allergoid consists of allergen covalently coupled to immunostimulatory oligodeoxynucleotide DNA sequences. RECENT FINDINGS:Recently, immunostimulatory oligodeox...

journal_title：Current opinion in allergy and clinical immunology

authors： Spiegelberg HL,Horner AA,Takabayashi K,Raz E

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency has been rediscovered as a public-health problem worldwide. It has been postulated that vitamin D deficiency may explain a portion of the asthma epidemic. The purpose of this review is to present the evidence for a role of vitamin D in asthma. RECENT FINDINGS:Both animal models a...

journal_title：Current opinion in allergy and clinical immunology

authors： Litonjua AA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Exhaled nitric oxide has been proposed as a useful noninvasive marker of airway inflammation in asthma. Great efforts have been made to standardize the methodology for exhaled nitric oxide measurement in both children and adults. As a consequence there is now an opportunity to establish the precise re...

journal_title：Current opinion in allergy and clinical immunology

authors： Payne DN

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent developments on the inter-relationship between food allergy and atopic eczema, with a particular focus on understanding the role of filaggrin gene defects. RECENT FINDINGS:Filaggrin gene defects have recently been identified as a major risk factor for the development of atopic eczema...

journal_title：Current opinion in allergy and clinical immunology

authors： Worth A,Sheikh A

更新日期：2010-06-01 00:00:00

abstract：:Fruits are increasingly recognized as a cause of food allergy. The wide cross-reactivity among these foods has been extensively studied. In this review we will focus on studies addressing the clinical relevance of cross-reactivity among fruits, the diagnostic management of patients complaining of reactions to multiple...

journal_title：Current opinion in allergy and clinical immunology

authors： Rodriguez J,Crespo JF

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Knowledge of the epidemiology, natural history and risk factors of insect-venom allergy is crucial for improving the clinical management of allergic patients. This review focuses on the recent research on these aspects of Hymenoptera-sting anaphylactic reactions. RECENT FINDINGS:The latest data from ...

journal_title：Current opinion in allergy and clinical immunology

authors： Bilò BM,Bonifazi F

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Ocular allergic contact dermatitis is a common yet challenging and frequently misdiagnosed condition. Inappropriate or delayed treatment can contribute to a variety of clinical symptoms such as tearing and itching with signs such as ptosis and cicatricial ectropion, resulting in deterioration of disea...

journal_title：Current opinion in allergy and clinical immunology

authors： Erdinest N,Nche E,London N,Solomon A

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis is a group of immunologically mediated diseases caused by an abnormal response to a wide variety of inhaled antigens. Its pathogenesis is complex and involves many immunological concepts. This review discusses recent advances in our understanding of the pathogenesis of hyp...

journal_title：Current opinion in allergy and clinical immunology

authors： Girard M,Israël-Assayag E,Cormier Y

更新日期：2004-04-01 00:00:00

abstract：PURPOSE:The aim of this review is to highlight the prevalence of allergic rhinitis in athletes and the impact this condition may have on their athletic performance. Furthermore, the optimal management of medical conditions in the elite athlete forms an important part of protecting the health of the athlete. RECENT FIN...

journal_title：Current opinion in allergy and clinical immunology

authors： Dijkstra HP,Robson-Ansley P

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To recognize the relevance of serum tryptase measurement as a useful tool for the diagnosis of allergic diseases and mast cell disorders. RECENT FINDINGS:Recent data on the role of mast cells and tryptase in allergic and other diseases provide new understanding into the mechanisms and causes of anaph...

journal_title：Current opinion in allergy and clinical immunology

authors： Bonadonna P,Scaffidi L,Boni E

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:In 2000, inhalation of butter flavoring vapors was first associated with clinical bronchiolitis obliterans among workers in microwave popcorn production. Toxicologic and epidemiologic studies in the succeeding 5 years have intervention and research implications. RECENT FINDINGS:Irreversible obstructi...

journal_title：Current opinion in allergy and clinical immunology

authors： Kreiss K

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the role of metropolitan endotoxin exposure in asthma and allergy, emphasizing recently published articles (i.e. April 2002-June 2003). RECENT FINDINGS:In infants and toddlers in metropolitan communities, higher endotoxin levels in house dust are associated with less atopy and increased whe...

journal_title：Current opinion in allergy and clinical immunology

authors： Song BJ,Liu AH

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases represent a growing global health concern, especially among pediatric populations. Current strategies for the treatment of allergies and asthma focus on limiting the severity of the symptoms; however, additional research investigating the mechanisms promoting inflammation in the cont...

journal_title：Current opinion in allergy and clinical immunology

authors： Inclan-Rico JM,Ponessa JJ,Siracusa MC

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Atopic dermatitis is typified by itchy, inflamed skin. It is increasingly common in the developed world and is a major cause of morbidity in infants and young children. Most children with the disease have high levels of immunoglobulin E and many have concomitant asthma. The cause of the disease is unk...

journal_title：Current opinion in allergy and clinical immunology

authors： Cookson WO,Moffatt MF

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases have only recently gained serious attention in Africa. This review discusses recent studies that have focused on allergy among Africans and people of African ancestry. RECENT FINDINGS:Time trend studies of the prevalence of allergies in Africa show a consistent increase over a perio...

journal_title：Current opinion in allergy and clinical immunology

authors： Obeng BB,Hartgers F,Boakye D,Yazdanbakhsh M

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Due to the continuously changing environmental conditions, it is necessary to regularly monitor and update the spectrum of contact allergens that elicit contact dermatitis. New contact allergens and known contact allergens with currently increasing importance need to be identified for diagnostic and p...

journal_title：Current opinion in allergy and clinical immunology

authors： Brasch J

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Gene therapy for severe combined immunodeficiency due to adenosine deaminase deficiency has moved from the early trials of safety and feasibility to recent studies demonstrating efficacy and clinical benefit. This review describes the latest advances in gene therapy trials for this condition using per...

journal_title：Current opinion in allergy and clinical immunology

authors： Aiuti A,Ficara F,Cattaneo F,Bordignon C,Roncarolo MG

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine in detail the new advances in the pathomechanisms and diagnosis of immediate and nonimmediate hypersensitivity reactions to quinolones, as well as analyze cross-reactivity among different quinolones. RECENT FINDINGS:Hypersensitivity reactions to quinolones, es...

journal_title：Current opinion in allergy and clinical immunology

authors： Blanca-López N,Andreu I,Torres Jaén MJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Cow's milk allergy affects 2-3% of young children, the economic impact of which necessitates search for simple diagnostic tools and affordable milk substitutes. This review examines recent studies on the diagnosis of cow's milk allergy as well as on the allergenicity of milk from other mammalian speci...

journal_title：Current opinion in allergy and clinical immunology

authors： Järvinen KM,Chatchatee P

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In this article we consider the characteristics that are associated with chemical respiratory allergens, and that may be essential for effective sensitization of the respiratory tract. RECENT FINDINGS:Chemical respiratory allergens share some characteristics with other chemical allergens, specificall...

journal_title：Current opinion in allergy and clinical immunology

authors： Kimber I,Dearman RJ

更新日期：2005-04-01 00:00:00