Contributions of innate lymphocytes to allergic responses.

abstract：PURPOSE OF REVIEW:Asthma is the most common, potentially serious medical problem to complicate pregnancy. Women with asthma have been shown to be at increased risk of complications during pregnancy. Managing asthma during pregnancy is unique because the effect of both the illness and the treatment on the developing fet...

journal_title：Current opinion in allergy and clinical immunology

authors： Namazy JA,Schatz M

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To remind readers that evaporative water loss from the airway surface is the stimulus for exercise-induced bronchoconstriction. To emphasize that recruitment of the peripheral airways determines severity of exercise-induced bronchoconstriction. To draw attention to the potential for injury of the epit...

journal_title：Current opinion in allergy and clinical immunology

authors： Anderson SD

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:During the past decade, easy access to sequence analyses has allowed us to increase our understanding of the pathogenesis of severe combined immunodeficiencies. Here, we describe the expanding clinical and immunological spectrum associated with Omenn syndrome phenotype. In particular, we review the ce...

journal_title：Current opinion in allergy and clinical immunology

authors： Marrella V,Maina V,Villa A

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergen immunotherapy (AIT) is still the only causal treatment for allergic rhinitis and asthma. However, conventional subcutaneous AIT administration schedules are time-consuming and safety issues still play a role; for sublingual AIT, the best efficacy is still investigated and for food allergy the...

journal_title：Current opinion in allergy and clinical immunology

authors： Larenas-Linnemann D

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the syndrome X-linked hypogammaglobulinemia with isolated growth hormone deficiency, focusing on the pedigree described originally. RECENT FINDINGS:An additional case of X-linked hypogammaglobulinemia with isolated growth hormone deficiency and an unaffected male have been bor...

journal_title：Current opinion in allergy and clinical immunology

authors： Stewart DM,Tian L,Notarangelo LD,Nelson DL

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenic mechanisms underlying the correlation between ocular allergy and dry eye disease (DED), highlighting how the first condition may be a risk factor for the second one. RECENT FINDINGS:Recent advances in our comprehension of the pathogenesis of ocular allergy and...

journal_title：Current opinion in allergy and clinical immunology

authors： Villani E,Rabbiolo G,Nucci P

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite asthma being widely regarded as a heterogeneous disease, a consensus for an accurate system of classification has not been agreed. Recent studies have suggested that the recognition of subphenotypes of asthma based on the pattern of airway inflammation may be particularly useful in increasing ...

journal_title：Current opinion in allergy and clinical immunology

authors： Green RH,Brightling CE,Bradding P

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Patient and physician perspectives on the impact of allergic rhinitis have previously been studied in the general population. We evaluated the burden of allergic rhinitis among patients from the members of European allergy patient organizations. The Patient Voice Allergy Survey was a quantitative, sel...

journal_title：Current opinion in allergy and clinical immunology

authors： Valovirta E,Myrseth SE,Palkonen S

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To present and discuss key design concepts for optimizing the impact of observational studies in the field of allergy and to highlight recent findings from NIAID-funded research networks. RECENT FINDINGS:We discuss three concepts. First, the benefit of prospective, longitudinal observational studies ...

journal_title：Current opinion in allergy and clinical immunology

authors： Rudman Spergel AK,Togias A

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the recent evidence on the effect of cleaning jobs on asthma, based on case reports and series of occupational asthma among cleaners, and epidemiological studies on the relationship between different characteristics of cleaning and asthma risk, as well as to ...

journal_title：Current opinion in allergy and clinical immunology

authors： Jaakkola JJ,Jaakkola MS

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need to discontinue the use of contact lenses. This review presents the ...

journal_title：Current opinion in allergy and clinical immunology

authors： Solomon A

更新日期：2016-10-01 00:00:00

abstract：:The complex relationship between allergen exposure, atopic sensitization and asthma in individuals and in populations has recently been a subject of controversy. A number of studies have demonstrated that allergen exposure in sensitized asthmatic individuals increases the severity of disease. A simple dose-response re...

journal_title：Current opinion in allergy and clinical immunology

authors： Custovic A,Woodcock A

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This article provides an overview of novel nanoscale structures potentially applicable to the field of allergy, and to discuss the required properties, advantages, and disadvantages of those nanostructures for clinical application focusing on diagnosis of drug hypersensitivity reactions. RECENT FINDI...

journal_title：Current opinion in allergy and clinical immunology

authors： Mayorga C,Perez-Inestrosa E,Molina N,Montañez MI

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:As drug allergy research aims to inform clinical practice, implementation of best practices may be influenced by financial resources required to incorporate new interventions and the resulting clinical and economic returns on those resource investments. The present review summarizes new insights into ...

journal_title：Current opinion in allergy and clinical immunology

authors： Mattingly TJ 2nd

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Although today's cornerstone therapies for asthma (inhaled bronchodilators and corticosteroids) target airway narrowing and lung inflammation, about half of treated asthmatic patients do not achieve good disease control. There is a clear need for new therapeutic approaches and novel drug targets. Rece...

journal_title：Current opinion in allergy and clinical immunology

authors： Grassin-Delyle S,Naline E,Devillier P

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Unverified penicillin allergy is being increasingly recognized as a public health concern. The ideal protocol for verifying true clinically significant IgE-mediated penicillin allergy needs to use only commercially available materials, be well tolerated and easy to perform in both the inpatient and ou...

journal_title：Current opinion in allergy and clinical immunology

authors： Macy E

更新日期：2015-08-01 00:00:00

abstract：:Fruits are increasingly recognized as a cause of food allergy. The wide cross-reactivity among these foods has been extensively studied. In this review we will focus on studies addressing the clinical relevance of cross-reactivity among fruits, the diagnostic management of patients complaining of reactions to multiple...

journal_title：Current opinion in allergy and clinical immunology

authors： Rodriguez J,Crespo JF

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The key features of aspirin-exacerbated respiratory diseases (AERDs) include chronic, severe asthma and a high prevalence (60-80%) of chronic rhinosinusitis with nasal polyps, all of which are exacerbated by exposure to aspirin and other NSAIDs. Although the pathogenic mechanisms of AERD are not compl...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi JH,Kim MA,Park HS

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Complementary medicines, including acupuncture and Chinese herbal medicine, are being used increasingly for the management of allergies such as allergic rhinitis. Until relatively recently, however, evidence for the efficacy and safety of these therapies in allergic conditions has been lacking. RECEN...

journal_title：Current opinion in allergy and clinical immunology

authors： Xue CC,Li CG,Hügel HM,Story DF

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Children with asthma require care that is seamlessly coordinated so that asthma symptoms are recognized and managed at home and at school. The purpose of this review is to discuss recent consensus recommendations in school-based asthma care. RECENT FINDINGS:The School-based Asthma Management Program ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kakumanu S,Antos N,Szefler SJ,Lemanske RF Jr

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Anaphylaxis due to ant sting is increasingly being recognized as a significant problem. Severe allergic reactions to ants are well described in the south-eastern United States, but have only been recognized in recent years as being important in other parts of the world. There are many different ant sp...

journal_title：Current opinion in allergy and clinical immunology

authors： Shek LP,Ngiam NS,Lee BW

更新日期：2004-08-01 00:00:00

abstract：PURPOSE OF REVIEW:One strategy to improve asthma control is to identify risk factors for uncontrolled asthma in epidemiologic studies and then consider those risk factors as potential targets for intervention. This article reviews predictors of impairment based on validated tools and predictors of severe asthma exacerb...

journal_title：Current opinion in allergy and clinical immunology

authors： Schatz M

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent application of advanced culture-independent molecular techniques for the identification of microorganisms has contributed to our knowledge on the role of early-life microbial exposure and colonization in health and disease. The purpose of this review is to present the current perspectives regar...

journal_title：Current opinion in allergy and clinical immunology

authors： Beigelman A,Weinstock GM,Bacharier LB

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will cover advances over the past year in defining airway endotypes in asthma by gene expression and the relationship between these endotypes and clinical traits. RECENT FINDINGS:Expression profiling studies of asthmatic airway samples continue to reveal significant heterogeneity in airwa...

journal_title：Current opinion in allergy and clinical immunology

authors： Wesolowska-Andersen A,Seibold MA

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Component-resolved diagnosis (CRD) is an advanced tool capable of aiding the clinician in fine tuning the diagnosis of the causal allergens of a reaction with the added value of providing information of severity risk, potential cross-reactivity, and subsequently, guiding management measures. This revi...

journal_title：Current opinion in allergy and clinical immunology

authors： Cardona V,Ansotegui IJ

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The autoimmune lymphoproliferative syndrome is a recently identified human disorder of lymphocyte apoptosis that has provided important information about Fas-mediated lymphocyte apoptosis. In this review we summarize current information regarding the diagnosis, management and underlying molecular basi...

journal_title：Current opinion in allergy and clinical immunology

authors： Oliveira JB,Fleisher T

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview on the role of gut mucosal immunity in the development of tolerance against allergy to food. RECENT FINDINGS:The gastrointestinal tract, through innate and specific immunologic factors, acts as a defense against ingested antigens. In addition to the mucous membrane integrity an...

journal_title：Current opinion in allergy and clinical immunology

authors： Chahine BG,Bahna SL

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the association between the common dominantly inherited genetic trait hereditary alpha-tryptasemia (HαT) and hymenoptera venom-induced anaphylaxis (HVA). RECENT FINDINGS:Elevated BST has been correlated with more severe systemic anaphylaxis in humans in a number of settings - most notably ...

journal_title：Current opinion in allergy and clinical immunology

authors： O'Connell MP,Lyons JJ

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Children living in US inner cities experience disparate burdens of asthma, especially in severity, impairment, exacerbations, and morbidity. Investigations seeking to better understand the factors and mechanisms underlying asthma prevalence, severity, and exacerbation in children living in these commu...

journal_title：Current opinion in allergy and clinical immunology

authors： Dutmer CM,Kim H,Searing DA,Zoratti EM,Liu AH

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth. RECENT FINDINGS:Studies on mice have revealed that apart from haemangi...

journal_title：Current opinion in allergy and clinical immunology

authors： Regenfuss B,Bock F,Cursiefen C

更新日期：2012-10-01 00:00:00