The relationships between environmental bacterial exposure, airway bacterial colonization, and asthma.

abstract：PURPOSE OF REVIEW:Targeting allergens to surface receptors on antigen presenting cells may provide a therapeutic strategy for allergic disease. This article discusses the immunomodulatory capacity of a molecule (H22-Fel d 1), which targets the major cat allergen, Fel d 1, to the high affinity IgG receptor, Fc gammaRI, ...

journal_title：Current opinion in allergy and clinical immunology

authors： Hulse KE,Woodfolk JA

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace. RECENT FINDINGS:Increased recruitment and infiltration of ne...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi Y,Lee Y,Park HS

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In the concept of food allergy prevention, no successful strategy could be identified until now. Although interventional trials using probiotics, prebiotics, hydrolyzed formula and bacterial lysates early in infancy were found to reduce the incidence of atopic dermatitis, no effect on food sensitizati...

journal_title：Current opinion in allergy and clinical immunology

authors： Lau S

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:There is an unmet need for better immunological tests in cases of suspected occupational asthma to many workplace chemicals; here we consider the basophil activation test (BAT), a potential alternative to the detection of specific IgE antibodies. RECENT FINDINGS:BAT is fairly widely used in general a...

journal_title：Current opinion in allergy and clinical immunology

authors： Vera-Berrios RN,Feary J,Cullinan P

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a brief discussion on the differential diagnosis for peripheral eosinophilia. We will then focus on targeted immunotherapies for atopic disease, their effects on absolute peripheral eosinophil counts, and use of peripheral eosinophils as a predictor of treatmen...

journal_title：Current opinion in allergy and clinical immunology

authors：

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the impact of globalization in the management of anaphylaxis and identify potential strategies to improve patients' care and prevention. RECENT FINDINGS:Developments in the field of anaphylaxis have been consistently following these globalization trends offering possibilities of collabo...

journal_title：Current opinion in allergy and clinical immunology

authors： Kase Tanno L,Ansotegui I,Demoly P,Joint Allergy Academies.

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma features a high degree of heterogeneity in both pathophysiology and therapeutic response, resulting in many asthma patients being treated inadequately. Biomarkers indicative of underlying pathological processes could be used to identify disease subtypes, determine prognosis and to predict or mo...

journal_title：Current opinion in allergy and clinical immunology

authors： Richards LB,Neerincx AH,van Bragt JJMH,Sterk PJ,Bel EHD,Maitland-van der Zee AH

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenic mechanisms underlying the correlation between ocular allergy and dry eye disease (DED), highlighting how the first condition may be a risk factor for the second one. RECENT FINDINGS:Recent advances in our comprehension of the pathogenesis of ocular allergy and...

journal_title：Current opinion in allergy and clinical immunology

authors： Villani E,Rabbiolo G,Nucci P

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence suggests that some structural changes caused by mucosal remodeling may be primarily irreversible, which theoretically challenges the current management model of chronic rhinosinusitis (CRS). The relationship between inflammation and remodeling in the mucosa remains complex, yet better underst...

journal_title：Current opinion in allergy and clinical immunology

authors： Bassiouni A,Chen PG,Wormald PJ

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyse the most recently published studies on the prevalence of allergic conjunctivitis alone or in association with allergic rhinitis, and the clinical and demographic aspects of the disease. RECENT FINDINGS:Allergic conjunctivitis or conjunctival symptoms are present in 30-71% of patients with ...

journal_title：Current opinion in allergy and clinical immunology

authors： Leonardi A,Castegnaro A,Valerio AL,Lazzarini D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Defining predisposition to allergic drug reactions has largely focussed on HLA associations, but other genetic and nongenetic factors are also likely to be involved. RECENT FINDINGS:Polymorphic genetic variants in cytokine genes, including IL-10, and co-signalling pathways, including CTLA4, have been...

journal_title：Current opinion in allergy and clinical immunology

authors： Gibson A,Ogese M,Pirmohamed M

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Anaphylaxis due to ant sting is increasingly being recognized as a significant problem. Severe allergic reactions to ants are well described in the south-eastern United States, but have only been recognized in recent years as being important in other parts of the world. There are many different ant sp...

journal_title：Current opinion in allergy and clinical immunology

authors： Shek LP,Ngiam NS,Lee BW

更新日期：2004-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Exhaled nitric oxide has been proposed as a useful noninvasive marker of airway inflammation in asthma. Great efforts have been made to standardize the methodology for exhaled nitric oxide measurement in both children and adults. As a consequence there is now an opportunity to establish the precise re...

journal_title：Current opinion in allergy and clinical immunology

authors： Payne DN

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:The aim of this review is to highlight the prevalence of allergic rhinitis in athletes and the impact this condition may have on their athletic performance. Furthermore, the optimal management of medical conditions in the elite athlete forms an important part of protecting the health of the athlete. RECENT FIN...

journal_title：Current opinion in allergy and clinical immunology

authors： Dijkstra HP,Robson-Ansley P

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To present the most recent evidence on beta-lactam hypersensitivity reactions in children. RECENT FINDINGS:Drug provocation tests (DPTs) are the gold standard when investigating beta-lactam allergy in children and evidence is increasingly supporting DPTs without skin tests as a safe approach when eva...

journal_title：Current opinion in allergy and clinical immunology

authors： Graham F,Tsabouri S,Caubet JC

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this article is to evaluate developments in the knowledge of suppressor of cytokine signaling (SOCS) protein ocular allergy and the potential of SOCS proteins as targets for therapeutic strategies. RECENT FINDINGS:The family of proteins designated SOCS proteins plays an important role in ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kubo M,Ozaki A,Tanaka S,Okamoto M,Fukushima A

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the diverse clinical manifestations of IgE-mediated allergy to ingested wheat and summarizes recent advances in characterization of clinically significant allergens and diagnostic workup. RECENT FINDINGS:Recent population-based studies have shown the prevalence of wheat allergy ...

journal_title：Current opinion in allergy and clinical immunology

authors： Inomata N

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:There is considerable evidence that implicates eosinophils as important effector cells in the inflammation characteristic of eosinophilic asthma. IL-5 is central to eosinophil maturation and release from the bone marrow, their subsequent accumulation, activation and persistence in the tissues. IL-5 th...

journal_title：Current opinion in allergy and clinical immunology

authors： Walsh GM

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing understanding of mechanisms and influencing factors in the development of uncontrolled inflammatory responses in atopy and asthma should serve for the introduction of new preventive measures. This review tries to present the current state of the art and resumes that until now, no really eff...

journal_title：Current opinion in allergy and clinical immunology

authors： Lau S

更新日期：2013-04-01 00:00:00

abstract：:Ants belong to the order Hymenoptera, along with bees, wasps, yellow jackets, etc., they are the most successful animal genera in this world. It is their selfless social structure which accounts for their huge impact. Their effect on man ranges from the parasol ant, which makes plant cultivation untenable in certain p...

journal_title：Current opinion in allergy and clinical immunology

authors： Rhoades R

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis is a group of immunologically mediated diseases caused by an abnormal response to a wide variety of inhaled antigens. Its pathogenesis is complex and involves many immunological concepts. This review discusses recent advances in our understanding of the pathogenesis of hyp...

journal_title：Current opinion in allergy and clinical immunology

authors： Girard M,Israël-Assayag E,Cormier Y

更新日期：2004-04-01 00:00:00

abstract：:Allergic diseases such as atopic dermatitis, rhinitis and asthma are thought to result from a dysregulated immune response to commonly encountered antigens in genetically predisposed individuals. This response leads to chronic eosinophil-rich allergic inflammation and is controlled by Th2 lymphocytes. The first step i...

journal_title：Current opinion in allergy and clinical immunology

authors： Lambrecht BN

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Unverified penicillin allergy is being increasingly recognized as a public health concern. The ideal protocol for verifying true clinically significant IgE-mediated penicillin allergy needs to use only commercially available materials, be well tolerated and easy to perform in both the inpatient and ou...

journal_title：Current opinion in allergy and clinical immunology

authors： Macy E

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:In 2000, inhalation of butter flavoring vapors was first associated with clinical bronchiolitis obliterans among workers in microwave popcorn production. Toxicologic and epidemiologic studies in the succeeding 5 years have intervention and research implications. RECENT FINDINGS:Irreversible obstructi...

journal_title：Current opinion in allergy and clinical immunology

authors： Kreiss K

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the immunology of chronic beryllium disease. It addresses the importance of the interaction between class II molecules and the T cells that recognize beryllium, along with the subsequent immune response that results in sensitization and disease, and genetic factors leading to var...

journal_title：Current opinion in allergy and clinical immunology

authors： Samuel G,Maier LA

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a fast overview about the introduction and development of anticholinergic drugs in Western medicine to their current indications particularly in asthma. RECENT FINDINGS:Although short-acting muscarinic antagonists have been positioned in the last 15 years for the treatment of adults and ch...

journal_title：Current opinion in allergy and clinical immunology

authors： Rodrigo GJ

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to describe the role of precision medicine in the diagnosis, treatment, and monitoring of cow's milk allergy. RECENT FINDINGS:The development of 'omics' sciences in the field of food allergy has led to a better understanding of the allergenicity of cow's milk proteins and si...

journal_title：Current opinion in allergy and clinical immunology

authors： D'Auria E,Venter C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic conjunctivitis is common and may be the most prominent or the only feature of allergies. Immunotherapy has been used as a primary treatment for allergies since the early 1900s. Currently the use of immunotherapy for allergic rhinoconjunctivitis is well established and has been shown to decrea...

journal_title：Current opinion in allergy and clinical immunology

authors： Bielory L,Mongia A

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent investigation has resulted in significant advances toward definitive therapeutic options for food allergy. In this review, we will explore novel immunotherapeutic interventions for the active treatment of food allergy. RECENT FINDINGS:Because the injection route for allergen immunotherapy to f...

journal_title：Current opinion in allergy and clinical immunology

authors： Scurlock AM,Jones SM

更新日期：2010-12-01 00:00:00

abstract：:This review summarizes recent advances and findings in the area of 'hidden' food allergens, i.e. allergenic foods that can either contaminate other foods, or be 'disguised' as part of a food, and cause allergic reactions. Newly emerging allergenic foods of increasing importance, recently developed methods for the dete...

journal_title：Current opinion in allergy and clinical immunology

authors： Hefle SL

更新日期：2001-06-01 00:00:00