Prevention of baker's asthma.

Abstract:

PURPOSE OF REVIEW:Baker's allergy and asthma continue to represent an important contributor of occupational asthma globally. This review identified recent studies related to the prevention of baker's allergy and asthma. RECENT FINDINGS:Studies with respect to regulatory exposure standards, workplace control measures aimed at reduction of flour dust exposures, surveillance programmes (exposure monitoring, medical surveillance) and workplace information, education and training programmes were identified. SUMMARY:Detailed knowledge on risk factors and detection methods to assess exposure and early identification of high-risk workers exist, but workplace control measures remain sub-optimal because they are rarely multifaceted. This is compounded by the lack of health-based exposure standards globally. Exposure level monitoring and medical surveillance are integral to assessing effectiveness of preventive strategies. Triage systems for optimizing the efficiency of medical surveillance programmes show promise, but need replication in different contexts. Future studies need to focus on evaluating the relevance and quantification of peak exposures in increasing risk; developing standardized respiratory questionnaires for medical surveillance; and further exploration of serial fractional exhaled nitric oxide (FeNO) measurements as an adjunct to allergic sensitization for the early identification of baker's asthma and assessing the long-term impact of interventions.

authors

Jeebhay MF,Baatjies R

doi

10.1097/ACI.0000000000000612

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

96-102

issue

2

eissn

1528-4050

issn

1473-6322

pii

00130832-202004000-00004

journal_volume

20

pub_type

杂志文章
  • Ocular allergic contact dermatitis from topical drugs.

    abstract:PURPOSE OF REVIEW:Ocular allergic contact dermatitis is a common yet challenging and frequently misdiagnosed condition. Inappropriate or delayed treatment can contribute to a variety of clinical symptoms such as tearing and itching with signs such as ptosis and cicatricial ectropion, resulting in deterioration of disea...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章

    doi:10.1097/ACI.0000000000000677

    authors: Erdinest N,Nche E,London N,Solomon A

    更新日期:2020-10-01 00:00:00

  • Role of suppressor of cytokine signaling in ocular allergy.

    abstract:PURPOSE OF REVIEW:The goal of this article is to evaluate developments in the knowledge of suppressor of cytokine signaling (SOCS) protein ocular allergy and the potential of SOCS proteins as targets for therapeutic strategies. RECENT FINDINGS:The family of proteins designated SOCS proteins plays an important role in ...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/01.all.0000244797.48981.6d

    authors: Kubo M,Ozaki A,Tanaka S,Okamoto M,Fukushima A

    更新日期:2006-10-01 00:00:00

  • Evidence of adherence to allergen-specific immunotherapy.

    abstract:PURPOSE OF REVIEW:The main feature of allergen-specific immunotherapy is its capacity to modify the natural history of the disease, reducing the development of asthma and new sensitizations after 3-4 years of treatment. For this reason, adherence to the therapy is mandatory, as happens for all chronic medical treatment...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e328332b8df

    authors: Senna G,Ridolo E,Calderon M,Lombardi C,Canonica GW,Passalacqua G

    更新日期:2009-12-01 00:00:00

  • Nitric oxide in allergic airway inflammation.

    abstract:PURPOSE OF REVIEW:Exhaled nitric oxide has been proposed as a useful noninvasive marker of airway inflammation in asthma. Great efforts have been made to standardize the methodology for exhaled nitric oxide measurement in both children and adults. As a consequence there is now an opportunity to establish the precise re...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/00130832-200304000-00007

    authors: Payne DN

    更新日期:2003-04-01 00:00:00

  • What makes a chemical a respiratory sensitizer?

    abstract:PURPOSE OF REVIEW:In this article we consider the characteristics that are associated with chemical respiratory allergens, and that may be essential for effective sensitization of the respiratory tract. RECENT FINDINGS:Chemical respiratory allergens share some characteristics with other chemical allergens, specificall...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/01.all.0000162302.82233.93

    authors: Kimber I,Dearman RJ

    更新日期:2005-04-01 00:00:00

  • Novel approaches in the treatment of allergic rhinitis.

    abstract:PURPOSE OF REVIEW:The increasing prevalence of allergic rhinitis, its impact on individual quality of life and social costs, as well as its role as a risk factor for asthma, underline the need for improved treatment options for this disorder. We reviewed the recent literature published in English, dealing with relevant...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/00130832-200302000-00004

    authors: Schultz A,Stuck BA,Feuring M,Hörmann K,Wehling M

    更新日期:2003-02-01 00:00:00

  • Updates on the use of inhaled corticosteroids in asthma.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to compare and contrast the newer inhaled corticosteroid (ICS) ciclesonide with older ICSs in terms of pharmacodynamic and pharmacokinetic properties and how these affect comparative efficacy. In addition, clinical dosing strategies for ICSs including as-needed use will b...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e328348a813

    authors: Stoloff SW,Kelly HW

    更新日期:2011-08-01 00:00:00

  • Omalizumab in chronic urticaria.

    abstract:PURPOSE OF REVIEW:The current EAACI/GA²LEN/EDF/WAO treatment guidelines for the management of urticaria recommend omalizumab as fourth-line therapy. Within the last year, many reports of omalizumab treatment in chronic urticaria have been published. RECENT FINDINGS:Two multicenter, randomized, placebo-controlled trial...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e328355365a

    authors: Metz M,Maurer M

    更新日期:2012-08-01 00:00:00

  • Novel antioxidant approaches to the treatment of upper airway inflammation.

    abstract:PURPOSE OF REVIEW:Current understanding of the role of oxidative stress in airway inflammation suggests that antioxidant therapy may be important to optimize the treatment. This review summarizes recent investigations of novel antioxidant agents for upper airway inflammation, with selected studies focused on lower airw...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e328334f613

    authors: Braskett M,Riedl MA

    更新日期:2010-02-01 00:00:00

  • Secondhand smoke at work.

    abstract:PURPOSE OF REVIEW:Secondhand smoke (SHS) exposure in the workplace remains common and has important acute and chronic health effects. The present study reviews the recent evidence linking workplace SHS exposure with poor health and the benefits of smoke-free workplace legislation. RECENT FINDINGS:Workplace SHS exposur...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e32833649b3

    authors: Eisner MD

    更新日期:2010-04-01 00:00:00

  • Corneal angiogenesis and lymphangiogenesis.

    abstract:PURPOSE OF REVIEW:The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth. RECENT FINDINGS:Studies on mice have revealed that apart from haemangi...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e328357b4a2

    authors: Regenfuss B,Bock F,Cursiefen C

    更新日期:2012-10-01 00:00:00

  • Proteomic applications in food allergy: food allergenomics.

    abstract:PURPOSE OF REVIEW:To familiarize the reader with the recent developments in the identification of food protein allergens by proteomics mass spectrometry-based methods, named allergenomics. RECENT FINDINGS:The proteomic analysis of food protein allergens has became a hot topic in the food safety field in recent years. ...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0000000000000160

    authors: Di Girolamo F,Muraca M,Mazzina O,Lante I,Dahdah L

    更新日期:2015-06-01 00:00:00

  • Immunology of chronic beryllium disease.

    abstract:PURPOSE OF REVIEW:This review discusses the immunology of chronic beryllium disease. It addresses the importance of the interaction between class II molecules and the T cells that recognize beryllium, along with the subsequent immune response that results in sensitization and disease, and genetic factors leading to var...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e3282f824a4

    authors: Samuel G,Maier LA

    更新日期:2008-04-01 00:00:00

  • Advances in ocular allergy: basic mechanisms, clinical patterns and new therapies.

    abstract::Ocular allergy presents unsolved mysteries in molecular and cellular mechanisms, and at the same time continues to challenge ophthalmologists daily in a wide array of disease forms. The recent understanding of the key role of the T helper type 2 cytokines, adhesion molecules and chemokines may provide future avenues f...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/01.all.0000011063.28808.cc

    authors: Solomon A,Pe'er J,Levi-Schaffer F

    更新日期:2001-10-01 00:00:00

  • An update on immunotherapy for food allergy.

    abstract:PURPOSE OF REVIEW:Recent investigation has resulted in significant advances toward definitive therapeutic options for food allergy. In this review, we will explore novel immunotherapeutic interventions for the active treatment of food allergy. RECENT FINDINGS:Because the injection route for allergen immunotherapy to f...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e32833fd5eb

    authors: Scurlock AM,Jones SM

    更新日期:2010-12-01 00:00:00

  • Hypersensitivity reactions to beta-lactams in children.

    abstract:PURPOSE OF REVIEW:To present the most recent evidence on beta-lactam hypersensitivity reactions in children. RECENT FINDINGS:Drug provocation tests (DPTs) are the gold standard when investigating beta-lactam allergy in children and evidence is increasingly supporting DPTs without skin tests as a safe approach when eva...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0000000000000453

    authors: Graham F,Tsabouri S,Caubet JC

    更新日期:2018-08-01 00:00:00

  • Can knowledge of the molecular structure of allergens improve immunotherapy?

    abstract::Conventional immunotherapy may be associated with the development of adverse reactions, including anaphylaxis, due to the use of increasing doses of allergen. Standardization of extracts is necessary in order to assess the correct amount of allergen administered. In recent years, increased knowledge on the molecular s...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/00130832-200112000-00010

    authors: Pomés A,Chapman MD

    更新日期:2001-12-01 00:00:00

  • Allergen immunotherapy: an update on protocols of administration.

    abstract:PURPOSE OF REVIEW:Allergen immunotherapy (AIT) is still the only causal treatment for allergic rhinitis and asthma. However, conventional subcutaneous AIT administration schedules are time-consuming and safety issues still play a role; for sublingual AIT, the best efficacy is still investigated and for food allergy the...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0000000000000220

    authors: Larenas-Linnemann D

    更新日期:2015-12-01 00:00:00

  • How does exercise cause asthma attacks?

    abstract:PURPOSE OF REVIEW:To remind readers that evaporative water loss from the airway surface is the stimulus for exercise-induced bronchoconstriction. To emphasize that recruitment of the peripheral airways determines severity of exercise-induced bronchoconstriction. To draw attention to the potential for injury of the epit...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/01.all.0000199797.02423.78

    authors: Anderson SD

    更新日期:2006-02-01 00:00:00

  • The genetics of atopic dermatitis.

    abstract:PURPOSE OF REVIEW:Atopic dermatitis is typified by itchy, inflamed skin. It is increasingly common in the developed world and is a major cause of morbidity in infants and young children. Most children with the disease have high levels of immunoglobulin E and many have concomitant asthma. The cause of the disease is unk...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/00130832-200210000-00003

    authors: Cookson WO,Moffatt MF

    更新日期:2002-10-01 00:00:00

  • Allergic manifestations of contact lens wearing.

    abstract:PURPOSE OF REVIEW:Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need to discontinue the use of contact lenses. This review presents the ...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0000000000000311

    authors: Solomon A

    更新日期:2016-10-01 00:00:00

  • Neutrophil activation in occupational asthma.

    abstract:PURPOSE OF REVIEW:The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace. RECENT FINDINGS:Increased recruitment and infiltration of ne...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0000000000000507

    authors: Choi Y,Lee Y,Park HS

    更新日期:2019-04-01 00:00:00

  • The role of environmental tobacco smoke in genetic susceptibility to asthma.

    abstract:PURPOSE OF REVIEW:The increase in asthma prevalence over the past 50 years suggests that exposures to environmental risk factors have also increased during this time. Environmental tobacco smoke is one of the most common indoor air pollutants and has been associated in epidemiologic studies with airway and allergic phe...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/00130832-200410000-00002

    authors: Kurz T,Ober C

    更新日期:2004-10-01 00:00:00

  • Component-resolved diagnostics in food allergy.

    abstract:PURPOSE OF REVIEW:The purpose of this paper is to review and discuss recent studies on component-resolved diagnostics in food allergy, involving panels of pure allergen molecules or arrays of peptides derived from allergen sequences, and to summarize the reporting of new food allergens during the past 2 years. RECENT ...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/01.all.0000225166.90768.d6

    authors: Lidholm J,Ballmer-Weber BK,Mari A,Vieths S

    更新日期:2006-06-01 00:00:00

  • Prenatal exposures and the development of childhood wheezing illnesses.

    abstract:PURPOSE OF REVIEW:To critically evaluate and summarize studies published between July 2015 and June 2016 linking prenatal exposures and the onset of childhood wheezing illnesses and to discuss future research directions in this field. RECENT FINDINGS:The aggregated evidence indicates a consistent detrimental effect of...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0000000000000342

    authors: Rosas-Salazar C,Hartert TV

    更新日期:2017-04-01 00:00:00

  • Animal models of anaphylaxis.

    abstract:PURPOSE OF REVIEW:In this review we will focus on recent advances in the role of mast cells in the pathophysiology of insect allergy and the possible mechanisms of mast cell activation in anaphylaxis. RECENT FINDINGS:Anaphylactic reactions in the mouse can be induced by several independent pathways involving immunoglo...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e32825ea543

    authors: Nauta A,Knippels L,Garssen J,Redegeld F

    更新日期:2007-08-01 00:00:00

  • Interrupting the cough reflex in asthma.

    abstract:PURPOSE OF REVIEW:Although cough is one of the defining symptoms of asthma, wheeze, chest tightness and breathlessness have generally received more attention. The impact of coughing for patients may be more important than currently appreciated and has been rated more troublesome than wheeze, chest tightness or disturba...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e328334e75f

    authors: Smith JA

    更新日期:2010-02-01 00:00:00

  • Biologic therapy for atopic asthma and beyond.

    abstract:PURPOSE OF REVIEW:Most asthma patients are easily managed with a standard combination of therapies consisting of inhaled controller and reliever drugs, but there remains a large unmet need at the severe end of the disease spectrum. For these patients, development of safer and more effective therapies for asthmatic pati...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0000000000000012

    authors: Caruso M,Crisafulli E,Lizzio R,Polosa R

    更新日期:2013-12-01 00:00:00

  • News from dendritic cells in atopic dermatitis.

    abstract:PURPOSE OF REVIEW:Dendritic cells are essential for the generation of innate and adaptive immune responses, which makes them stay on center stage when studying the immuno pathogenesis of atopic dermatitis. This review will discuss recent findings on the role of dendritic cells subsets in atopic dermatitis and will repo...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/ACI.0b013e32834a977a

    authors: Schäkel K,Hänsel A

    更新日期:2011-10-01 00:00:00

  • Beyond allergen avoidance: update on developing therapies for peanut allergy.

    abstract:PURPOSE OF REVIEW:Food allergy has emerged as a significant health problem. Peanut allergy is a major cause of food-induced fatal and near fatal anaphylactic reactions, and the incidence in children is increasing. Attempts to manage peanut allergy by strict avoidance are often unsuccessful. The purpose of this review i...

    journal_title:Current opinion in allergy and clinical immunology

    pub_type: 杂志文章,评审

    doi:10.1097/01.all.0000168796.20324.bd

    authors: Li XM

    更新日期:2005-06-01 00:00:00