Prenatal exposures and the development of childhood wheezing illnesses.

abstract：PURPOSE OF REVIEW:We provide an overview on the latest developments in primary immunodeficiency registries worldwide, on the basis of the recent literature amended by some older references to achieve completeness. RECENT FINDINGS:New primary immunodeficiency registries are emerging worldwide, although existing databas...

journal_title：Current opinion in allergy and clinical immunology

authors： Kindle G,Gathmann B,Grimbacher B

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the results from recent studies that assessed the burden of allergic diseases on the patients' every-day life, or contributed to new advances in monitoring quality-of-life in allergic disorders. This review will not report the numerous clinical trials that included quality-of-life as an outc...

journal_title：Current opinion in allergy and clinical immunology

authors： Leynaert B,Soussan D

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In adults with eosinophilic esophagitis (EoE), a chronic, inflammatory immune-mediated condition of the esophagus, both inflammation and fibrosis are likely associated with symptom generation. Therefore, assessing symptom-based patient-reported outcomes (PROs), defined by US Food and Drug Administrati...

journal_title：Current opinion in allergy and clinical immunology

authors： Safroneeva E,Schoepfer AM

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Secondhand smoke (SHS) exposure in the workplace remains common and has important acute and chronic health effects. The present study reviews the recent evidence linking workplace SHS exposure with poor health and the benefits of smoke-free workplace legislation. RECENT FINDINGS:Workplace SHS exposur...

journal_title：Current opinion in allergy and clinical immunology

authors： Eisner MD

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the diverse clinical manifestations of IgE-mediated allergy to ingested wheat and summarizes recent advances in characterization of clinically significant allergens and diagnostic workup. RECENT FINDINGS:Recent population-based studies have shown the prevalence of wheat allergy ...

journal_title：Current opinion in allergy and clinical immunology

authors： Inomata N

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Biological hypersensitivity to environmental stimuli is a fundamental feature of atopy predisposing to a number of clinically expressed disorders including allergic rhinitis, atopic dermatitis or eczema, and allergic asthma. There is provocative evidence that psychological stress constitutes an increa...

journal_title：Current opinion in allergy and clinical immunology

authors： Wright RJ,Cohen RT,Cohen S

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth. RECENT FINDINGS:Studies on mice have revealed that apart from haemangi...

journal_title：Current opinion in allergy and clinical immunology

authors： Regenfuss B,Bock F,Cursiefen C

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective immediate reactions to NSAIDs imply that patients develop a urticarial/anaphylactic response to a single drug with good tolerance to other compounds. No systematic review of these reactions has yet been made. RECENT FINDINGS:With the increase in consumption of NSAIDs, these have become one ...

journal_title：Current opinion in allergy and clinical immunology

authors： Canto MG,Andreu I,Fernandez J,Blanca M

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Complementary medicines, including acupuncture and Chinese herbal medicine, are being used increasingly for the management of allergies such as allergic rhinitis. Until relatively recently, however, evidence for the efficacy and safety of these therapies in allergic conditions has been lacking. RECEN...

journal_title：Current opinion in allergy and clinical immunology

authors： Xue CC,Li CG,Hügel HM,Story DF

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:New biological agents, in addition to the well-established omalizumab, have been nowadays introduced into clinical practice for severe asthma. This suggested the possibility of an at-home self-administration, as currently happening for other biological agents for immune-mediated diseases. RECENT FIND...

journal_title：Current opinion in allergy and clinical immunology

authors： Lombardi C,Bagnasco D,Passalacqua G

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent investigation has resulted in significant advances toward definitive therapeutic options for food allergy. In this review, we will explore novel immunotherapeutic interventions for the active treatment of food allergy. RECENT FINDINGS:Because the injection route for allergen immunotherapy to f...

journal_title：Current opinion in allergy and clinical immunology

authors： Scurlock AM,Jones SM

更新日期：2010-12-01 00:00:00

abstract：:This review summarizes recent advances and findings in the area of 'hidden' food allergens, i.e. allergenic foods that can either contaminate other foods, or be 'disguised' as part of a food, and cause allergic reactions. Newly emerging allergenic foods of increasing importance, recently developed methods for the dete...

journal_title：Current opinion in allergy and clinical immunology

authors： Hefle SL

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To present and discuss key design concepts for optimizing the impact of observational studies in the field of allergy and to highlight recent findings from NIAID-funded research networks. RECENT FINDINGS:We discuss three concepts. First, the benefit of prospective, longitudinal observational studies ...

journal_title：Current opinion in allergy and clinical immunology

authors： Rudman Spergel AK,Togias A

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic rhinitis due its high prevalence and burden needs to be properly treated. The disease's clinical features impose well tolerated drugs usable for long-term treatment. Nowadays, second-generation antihistamines and inhaled steroids represent the milestone of rhinitis therapy. The aim of the pre...

journal_title：Current opinion in allergy and clinical immunology

authors： Braido F,Arcadipane F,Marugo F,Hayashi M,Pawankar R

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma affects more than 25 million people worldwide and continues to grow in prevalence. According to a center for disease control and prevention (CDC) report, the total annual cost of asthma in the United States between 2008 and 2013, including medical care, absenteeism, and mortality, was $81.9 bil...

journal_title：Current opinion in allergy and clinical immunology

authors： Nalin U,Stout S,Portnoy JM

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update of recent research on the role of magnesium in the management of asthma. RECENT FINDINGS:Further evidence has been published that long-term oral magnesium supplementation does not lead to improved control in adult asthma. In contrast, updated meta-analyses of randomized controlle...

journal_title：Current opinion in allergy and clinical immunology

authors： Beasley R,Aldington S

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe recent approaches aimed at improving the treatment of allergic diseases through allergen-specific immunotherapy (SIT). Special emphasis will be given to the approach based on specific targeting of the major histocompatibility complex (MHC) class-II anti...

journal_title：Current opinion in allergy and clinical immunology

authors： Crameri R,Kündig TM,Akdis CA

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenic mechanisms underlying the correlation between ocular allergy and dry eye disease (DED), highlighting how the first condition may be a risk factor for the second one. RECENT FINDINGS:Recent advances in our comprehension of the pathogenesis of ocular allergy and...

journal_title：Current opinion in allergy and clinical immunology

authors： Villani E,Rabbiolo G,Nucci P

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Current understanding of the role of oxidative stress in airway inflammation suggests that antioxidant therapy may be important to optimize the treatment. This review summarizes recent investigations of novel antioxidant agents for upper airway inflammation, with selected studies focused on lower airw...

journal_title：Current opinion in allergy and clinical immunology

authors： Braskett M,Riedl MA

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the recent evidence on the effect of cleaning jobs on asthma, based on case reports and series of occupational asthma among cleaners, and epidemiological studies on the relationship between different characteristics of cleaning and asthma risk, as well as to ...

journal_title：Current opinion in allergy and clinical immunology

authors： Jaakkola JJ,Jaakkola MS

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The autoimmune lymphoproliferative syndrome is a recently identified human disorder of lymphocyte apoptosis that has provided important information about Fas-mediated lymphocyte apoptosis. In this review we summarize current information regarding the diagnosis, management and underlying molecular basi...

journal_title：Current opinion in allergy and clinical immunology

authors： Oliveira JB,Fleisher T

更新日期：2004-12-01 00:00:00

abstract：:Ants belong to the order Hymenoptera, along with bees, wasps, yellow jackets, etc., they are the most successful animal genera in this world. It is their selfless social structure which accounts for their huge impact. Their effect on man ranges from the parasol ant, which makes plant cultivation untenable in certain p...

journal_title：Current opinion in allergy and clinical immunology

authors： Rhoades R

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing understanding of mechanisms and influencing factors in the development of uncontrolled inflammatory responses in atopy and asthma should serve for the introduction of new preventive measures. This review tries to present the current state of the art and resumes that until now, no really eff...

journal_title：Current opinion in allergy and clinical immunology

authors： Lau S

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite increased clinician awareness, nonadherence to inhaled corticosteroid treatment presents a major challenge to successful asthma management and risks inappropriate treatment escalation, particularly in severe disease. In patients with Type-2 mediated biology, fractional exhaled nitric oxide (Fe...

journal_title：Current opinion in allergy and clinical immunology

authors： Butler CA,Heaney LG

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent developments on the inter-relationship between food allergy and atopic eczema, with a particular focus on understanding the role of filaggrin gene defects. RECENT FINDINGS:Filaggrin gene defects have recently been identified as a major risk factor for the development of atopic eczema...

journal_title：Current opinion in allergy and clinical immunology

authors： Worth A,Sheikh A

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we herein describe the progress in management of severe asthma, evolving from a 'blockbuster approach' to a more personalized approach targeted to the utilization of endotype-driven therapies. RECENT FINDINGS:Severe asthma characterization in phenotypes and endotypes, by means of spec...

journal_title：Current opinion in allergy and clinical immunology

authors： Canonica GW,Ferrando M,Baiardini I,Puggioni F,Racca F,Passalacqua G,Heffler E

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent insight into the efficacy of intranasal corticosteroids in treating ocular signs and symptoms of allergic rhinoconjunctivitis. RECENT FINDINGS:The efficacy of intranasal corticosteroids in treating allergic nasal symptoms is well established, and recent evidence indicates that this...

journal_title：Current opinion in allergy and clinical immunology

authors： Origlieri C,Bielory L

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergen-specific immunotherapy is the only curative treatment for allergic diseases. In spite of the great progress in both vaccine development and the methods of allergen immunotherapy (AIT) in recent years, several key problems related to limited efficacy, side-effects, low patient adherence and th...

journal_title：Current opinion in allergy and clinical immunology

authors： Jutel M,Akdis CA

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The incidence of food allergy is increasing. Correct diagnosis is dependent on food challenges, which are not always performed, but more often based on history, skin prick test and specific IgE, leading to possible misdiagnoses. Mucosal provocation tests have been proposed as possible new diagnostic t...

journal_title：Current opinion in allergy and clinical immunology

authors： Kvenshagen BK,Jacobsen M

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis is a group of immunologically mediated diseases caused by an abnormal response to a wide variety of inhaled antigens. Its pathogenesis is complex and involves many immunological concepts. This review discusses recent advances in our understanding of the pathogenesis of hyp...

journal_title：Current opinion in allergy and clinical immunology

authors： Girard M,Israël-Assayag E,Cormier Y

更新日期：2004-04-01 00:00:00