The value of mucosal allergen challenge for the diagnosis of food allergy.

abstract：PURPOSE OF REVIEW:An exposition of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to recommendations. RECENT FINDINGS:In this review, we outline the process whereby the strength of evidence from the literature undergoes a systematic reappraisal. The GRADE system allows four grad...

journal_title：Current opinion in allergy and clinical immunology

authors： Terracciano L,Brozek J,Compalati E,Schünemann H

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent application of advanced culture-independent molecular techniques for the identification of microorganisms has contributed to our knowledge on the role of early-life microbial exposure and colonization in health and disease. The purpose of this review is to present the current perspectives regar...

journal_title：Current opinion in allergy and clinical immunology

authors： Beigelman A,Weinstock GM,Bacharier LB

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Irreversible airflow limitation develops in some patients with asthma and is related to poorer prognosis. This paper reviews recent literature on natural course, risk factors, and potential mechanisms of persistent airflow limitation in asthma. RECENT FINDINGS:The natural course of persistent airflow...

journal_title：Current opinion in allergy and clinical immunology

authors： ten Brinke A

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We provide an overview on the latest developments in primary immunodeficiency registries worldwide, on the basis of the recent literature amended by some older references to achieve completeness. RECENT FINDINGS:New primary immunodeficiency registries are emerging worldwide, although existing databas...

journal_title：Current opinion in allergy and clinical immunology

authors： Kindle G,Gathmann B,Grimbacher B

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is prevalent in inner-city populations, exhibiting significant morbidity and mortality. This review focuses on the consequential findings of recent literature, providing insight into onset of asthma, complicating factors, prediction of exacerbations, and novel treatment strategies. RECENT FIND...

journal_title：Current opinion in allergy and clinical immunology

authors： Dutmer CM,McGraw MD,Liu AH

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The frequency of hospitalization for anaphylaxis has increased over the last 20 years across Europe, Australia, and North America, particularly, for food and medication triggers. Adolescents show the highest risk for morbidity and fatality from food-induced anaphylaxis, yet there is little high-qualit...

journal_title：Current opinion in allergy and clinical immunology

authors： Comberiati P,Spahn J,Peroni DG

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:During the past decade, easy access to sequence analyses has allowed us to increase our understanding of the pathogenesis of severe combined immunodeficiencies. Here, we describe the expanding clinical and immunological spectrum associated with Omenn syndrome phenotype. In particular, we review the ce...

journal_title：Current opinion in allergy and clinical immunology

authors： Marrella V,Maina V,Villa A

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Key aspects and outcomes from the recently published guidance on the regulation of allergen products are summarized. RECENT FINDINGS:A new regulatory guideline has been published to enhance harmonized national approaches on the regulation of allergen products and thereby strengthen the availability o...

journal_title：Current opinion in allergy and clinical immunology

authors： Bonertz A,Mahler V,Vieths S

更新日期：2020-12-01 00:00:00

abstract：:Allergic diseases such as atopic dermatitis, rhinitis and asthma are thought to result from a dysregulated immune response to commonly encountered antigens in genetically predisposed individuals. This response leads to chronic eosinophil-rich allergic inflammation and is controlled by Th2 lymphocytes. The first step i...

journal_title：Current opinion in allergy and clinical immunology

authors： Lambrecht BN

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Ocular allergy is often encountered by allergists, ophthalmologists, pediatricians, and primary care physicians. An understanding of the immunologic mechanisms, the differential diagnosis, the clinical features, and the treatment of ocular allergy will be useful to all physicians who encounter these p...

journal_title：Current opinion in allergy and clinical immunology

authors： Friedlaender MH

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The increasing prevalence of allergic rhinitis, its impact on individual quality of life and social costs, as well as its role as a risk factor for asthma, underline the need for improved treatment options for this disorder. We reviewed the recent literature published in English, dealing with relevant...

journal_title：Current opinion in allergy and clinical immunology

authors： Schultz A,Stuck BA,Feuring M,Hörmann K,Wehling M

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To present and discuss key design concepts for optimizing the impact of observational studies in the field of allergy and to highlight recent findings from NIAID-funded research networks. RECENT FINDINGS:We discuss three concepts. First, the benefit of prospective, longitudinal observational studies ...

journal_title：Current opinion in allergy and clinical immunology

authors： Rudman Spergel AK,Togias A

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a brief discussion on the differential diagnosis for peripheral eosinophilia. We will then focus on targeted immunotherapies for atopic disease, their effects on absolute peripheral eosinophil counts, and use of peripheral eosinophils as a predictor of treatmen...

journal_title：Current opinion in allergy and clinical immunology

authors：

更新日期：2020-04-01 00:00:00

abstract：:This review summarizes recent advances and findings in the area of 'hidden' food allergens, i.e. allergenic foods that can either contaminate other foods, or be 'disguised' as part of a food, and cause allergic reactions. Newly emerging allergenic foods of increasing importance, recently developed methods for the dete...

journal_title：Current opinion in allergy and clinical immunology

authors： Hefle SL

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this article is to evaluate developments in the knowledge of suppressor of cytokine signaling (SOCS) protein ocular allergy and the potential of SOCS proteins as targets for therapeutic strategies. RECENT FINDINGS:The family of proteins designated SOCS proteins plays an important role in ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kubo M,Ozaki A,Tanaka S,Okamoto M,Fukushima A

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Baker's allergy and asthma continue to represent an important contributor of occupational asthma globally. This review identified recent studies related to the prevention of baker's allergy and asthma. RECENT FINDINGS:Studies with respect to regulatory exposure standards, workplace control measures a...

journal_title：Current opinion in allergy and clinical immunology

authors： Jeebhay MF,Baatjies R

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic rhinitis due its high prevalence and burden needs to be properly treated. The disease's clinical features impose well tolerated drugs usable for long-term treatment. Nowadays, second-generation antihistamines and inhaled steroids represent the milestone of rhinitis therapy. The aim of the pre...

journal_title：Current opinion in allergy and clinical immunology

authors： Braido F,Arcadipane F,Marugo F,Hayashi M,Pawankar R

更新日期：2014-04-01 00:00:00

abstract：:A number of recent cohort and cross-sectional studies have contributed substantial knowledge to factors that influence the early development of asthma. Here, we summarize the recent evidence for the role of early life events such as prenatal factors, infections, diet and allergen exposure, and discuss the implications...

journal_title：Current opinion in allergy and clinical immunology

authors： Peat JK,Mellis CM

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the strengths and challenges of using whole genome sequencing (WGS)/whole exome sequencing (WES) for identifying novel genetic causes of primary immunodeficiencies. RECENT FINDINGS:WGS permits comprehensive sequencing of introns and exons, whereas WES allows deeper sequencing of...

journal_title：Current opinion in allergy and clinical immunology

authors： Chou J,Ohsumi TK,Geha RS

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is the most common, potentially serious medical problem to complicate pregnancy. Women with asthma have been shown to be at increased risk of complications during pregnancy. Managing asthma during pregnancy is unique because the effect of both the illness and the treatment on the developing fet...

journal_title：Current opinion in allergy and clinical immunology

authors： Namazy JA,Schatz M

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the immunology of chronic beryllium disease. It addresses the importance of the interaction between class II molecules and the T cells that recognize beryllium, along with the subsequent immune response that results in sensitization and disease, and genetic factors leading to var...

journal_title：Current opinion in allergy and clinical immunology

authors： Samuel G,Maier LA

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To present an update on the recent advances in the understanding of the mechanisms and practical management of oral mite anaphylaxis (OMA, pancake syndrome). RECENT FINDINGS:Among novel observations regarding OMA, this review highlights the increased prevalence of aspirin/NSAID hypersensitivity inpat...

journal_title：Current opinion in allergy and clinical immunology

authors： Sánchez-Borges M,Capriles-Hulett A,Fernandez-Caldas E

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the results from recent studies that assessed the burden of allergic diseases on the patients' every-day life, or contributed to new advances in monitoring quality-of-life in allergic disorders. This review will not report the numerous clinical trials that included quality-of-life as an outc...

journal_title：Current opinion in allergy and clinical immunology

authors： Leynaert B,Soussan D

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to compare and contrast the newer inhaled corticosteroid (ICS) ciclesonide with older ICSs in terms of pharmacodynamic and pharmacokinetic properties and how these affect comparative efficacy. In addition, clinical dosing strategies for ICSs including as-needed use will b...

journal_title：Current opinion in allergy and clinical immunology

authors： Stoloff SW,Kelly HW

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review addresses the most recent literature regarding the diagnosis of drug hypersensitivity reactions, which can be classified as immediate or nonimmediate according to the time interval between the last drug administration and the onset. Immediate reactions occur within 1 h; nonimmediate...

journal_title：Current opinion in allergy and clinical immunology

authors： Romano A,Demoly P

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the theoretical background and current evidence regarding parent-initiated oral corticosteroid (PIOCS) therapy in preschool wheeze and asthma in school-aged children. RECENT FINDINGS:In school-aged children with asthma PIOCS, given during acute episodes, has been associated with a modest re...

journal_title：Current opinion in allergy and clinical immunology

authors： Vuillermin PJ,Robertson CF,South M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Innate lymphoid type 2 cells (ILC2) have a critical role in the initiation and regulation of type 2 immune responses and are recognized as an important source of type-2 cytokines. Here, we present recent findings of the role of ILC2 in the integration, processing, and coordination of innate and adapti...

journal_title：Current opinion in allergy and clinical immunology

authors： Vreugde S,Wormald PJ

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review and discuss recent studies on component-resolved diagnostics in food allergy, involving panels of pure allergen molecules or arrays of peptides derived from allergen sequences, and to summarize the reporting of new food allergens during the past 2 years. RECENT ...

journal_title：Current opinion in allergy and clinical immunology

authors： Lidholm J,Ballmer-Weber BK,Mari A,Vieths S

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:An inverse relationship between resistance to certain parasitic diseases and measures of atopy and asthma has long been observed. A possible explanation is that genetic determinants which confer protection against detrimental worm burdens are the same determinants involved in atopic asthma. The focus ...

journal_title：Current opinion in allergy and clinical immunology

authors： Barnes KC,Grant AV,Gao P

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent insight into the efficacy of intranasal corticosteroids in treating ocular signs and symptoms of allergic rhinoconjunctivitis. RECENT FINDINGS:The efficacy of intranasal corticosteroids in treating allergic nasal symptoms is well established, and recent evidence indicates that this...

journal_title：Current opinion in allergy and clinical immunology

authors： Origlieri C,Bielory L

更新日期：2008-10-01 00:00:00