Early predictors of asthma.

abstract：PURPOSE OF REVIEW:Exhaled nitric oxide has been proposed as a useful noninvasive marker of airway inflammation in asthma. Great efforts have been made to standardize the methodology for exhaled nitric oxide measurement in both children and adults. As a consequence there is now an opportunity to establish the precise re...

journal_title：Current opinion in allergy and clinical immunology

authors： Payne DN

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is prevalent in inner-city populations, exhibiting significant morbidity and mortality. This review focuses on the consequential findings of recent literature, providing insight into onset of asthma, complicating factors, prediction of exacerbations, and novel treatment strategies. RECENT FIND...

journal_title：Current opinion in allergy and clinical immunology

authors： Dutmer CM,McGraw MD,Liu AH

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis is a group of immunologically mediated diseases caused by an abnormal response to a wide variety of inhaled antigens. Its pathogenesis is complex and involves many immunological concepts. This review discusses recent advances in our understanding of the pathogenesis of hyp...

journal_title：Current opinion in allergy and clinical immunology

authors： Girard M,Israël-Assayag E,Cormier Y

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The incidence of food allergy is increasing. Correct diagnosis is dependent on food challenges, which are not always performed, but more often based on history, skin prick test and specific IgE, leading to possible misdiagnoses. Mucosal provocation tests have been proposed as possible new diagnostic t...

journal_title：Current opinion in allergy and clinical immunology

authors： Kvenshagen BK,Jacobsen M

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to compare and contrast the newer inhaled corticosteroid (ICS) ciclesonide with older ICSs in terms of pharmacodynamic and pharmacokinetic properties and how these affect comparative efficacy. In addition, clinical dosing strategies for ICSs including as-needed use will b...

journal_title：Current opinion in allergy and clinical immunology

authors： Stoloff SW,Kelly HW

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To remind readers that evaporative water loss from the airway surface is the stimulus for exercise-induced bronchoconstriction. To emphasize that recruitment of the peripheral airways determines severity of exercise-induced bronchoconstriction. To draw attention to the potential for injury of the epit...

journal_title：Current opinion in allergy and clinical immunology

authors： Anderson SD

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:In 2000, inhalation of butter flavoring vapors was first associated with clinical bronchiolitis obliterans among workers in microwave popcorn production. Toxicologic and epidemiologic studies in the succeeding 5 years have intervention and research implications. RECENT FINDINGS:Irreversible obstructi...

journal_title：Current opinion in allergy and clinical immunology

authors： Kreiss K

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To familiarize the reader with the recent developments in the identification of food protein allergens by proteomics mass spectrometry-based methods, named allergenomics. RECENT FINDINGS:The proteomic analysis of food protein allergens has became a hot topic in the food safety field in recent years. ...

journal_title：Current opinion in allergy and clinical immunology

authors： Di Girolamo F,Muraca M,Mazzina O,Lante I,Dahdah L

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyse the most recently published studies on the prevalence of allergic conjunctivitis alone or in association with allergic rhinitis, and the clinical and demographic aspects of the disease. RECENT FINDINGS:Allergic conjunctivitis or conjunctival symptoms are present in 30-71% of patients with ...

journal_title：Current opinion in allergy and clinical immunology

authors： Leonardi A,Castegnaro A,Valerio AL,Lazzarini D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Component-resolved diagnosis (CRD) is an advanced tool capable of aiding the clinician in fine tuning the diagnosis of the causal allergens of a reaction with the added value of providing information of severity risk, potential cross-reactivity, and subsequently, guiding management measures. This revi...

journal_title：Current opinion in allergy and clinical immunology

authors： Cardona V,Ansotegui IJ

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to recap recent published data on immunological mechanisms underlying sublingual immunotherapy (SLIT). RECENT FINDINGS:Although several alternative noninvasive allergen application strategies have been investigated in allergen-specific immunotherapy, local intraoral allergen applicat...

journal_title：Current opinion in allergy and clinical immunology

authors： Allam JP,Novak N

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Mast cells and eosinophils are the main effector cells in allergic inflammation, but there is now compelling evidence that fibroblasts are also important players in the inflammatory response. In fact, they respond to different stimuli and release several mediators that modulate mast-cell and eosinophi...

journal_title：Current opinion in allergy and clinical immunology

authors： Solomon A,Puxeddu I,Levi-Schaffer F

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Children living in US inner cities experience disparate burdens of asthma, especially in severity, impairment, exacerbations, and morbidity. Investigations seeking to better understand the factors and mechanisms underlying asthma prevalence, severity, and exacerbation in children living in these commu...

journal_title：Current opinion in allergy and clinical immunology

authors： Dutmer CM,Kim H,Searing DA,Zoratti EM,Liu AH

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent findings on the skin microbiome. It provides an update on the current understanding of the role of microbiota in healthy skin and in inflammatory and allergic skin diseases. RECENT FINDINGS:Advances in computing and high-throughput sequencing technology have enabled in-dep...

journal_title：Current opinion in allergy and clinical immunology

authors： Zeeuwen PL,Kleerebezem M,Timmerman HM,Schalkwijk J

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Personalized medicine encompasses the use of biological information such as genomics to provide tailored interventions for patients. The review explores the ethical, legal, and social issues that have emerged with personalized medicine and must be considered because of the complex nature of providing ...

journal_title：Current opinion in allergy and clinical immunology

authors： Joly Y,Saulnier KM,Osien G,Knoppers BM

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the immunology of chronic beryllium disease. It addresses the importance of the interaction between class II molecules and the T cells that recognize beryllium, along with the subsequent immune response that results in sensitization and disease, and genetic factors leading to var...

journal_title：Current opinion in allergy and clinical immunology

authors： Samuel G,Maier LA

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to describe the role of precision medicine in the diagnosis, treatment, and monitoring of cow's milk allergy. RECENT FINDINGS:The development of 'omics' sciences in the field of food allergy has led to a better understanding of the allergenicity of cow's milk proteins and si...

journal_title：Current opinion in allergy and clinical immunology

authors： D'Auria E,Venter C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to introduce recent findings on the pathomechanisms of toxic epidermal necrolysis (TEN), which is characterized by widespread epidermal detachment due to keratinocyte apoptosis. RECENT FINDINGS:In the mechanism of epidermal damage, the roles of drug metabolites, c...

journal_title：Current opinion in allergy and clinical immunology

authors： Tohyama M,Hashimoto K

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Sublingual immunotherapy is currently accepted as a viable therapeutic option, and is widely used in many European countries. In the past 2 years, new data concerning clinical, immunological and practical aspects of sublingual immunotherapy have been published, and many critical points have been addre...

journal_title：Current opinion in allergy and clinical immunology

authors： Passalacqua G,Canonica GW

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Knowledge of the epidemiology, natural history and risk factors of insect-venom allergy is crucial for improving the clinical management of allergic patients. This review focuses on the recent research on these aspects of Hymenoptera-sting anaphylactic reactions. RECENT FINDINGS:The latest data from ...

journal_title：Current opinion in allergy and clinical immunology

authors： Bilò BM,Bonifazi F

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The increase in asthma prevalence over the past 50 years suggests that exposures to environmental risk factors have also increased during this time. Environmental tobacco smoke is one of the most common indoor air pollutants and has been associated in epidemiologic studies with airway and allergic phe...

journal_title：Current opinion in allergy and clinical immunology

authors： Kurz T,Ober C

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:An inverse relationship between resistance to certain parasitic diseases and measures of atopy and asthma has long been observed. A possible explanation is that genetic determinants which confer protection against detrimental worm burdens are the same determinants involved in atopic asthma. The focus ...

journal_title：Current opinion in allergy and clinical immunology

authors： Barnes KC,Grant AV,Gao P

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe adverse drug reactions. Once thought to be idiosyncratic and unpredictable, there has been significant progress made in the understanding of the pathomechanism and pharmacogenetics of such reactions. These ...

journal_title：Current opinion in allergy and clinical immunology

authors： Lee HY,Chung WH

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight recent advances in gene-expression profiling of nasal polyps in patients with chronic rhinosinusitis and aspirin-sensitive asthma. RECENT FINDINGS:Gene-expression profiling has allowed simultaneous interrogation of thousands of genes, including the entire ge...

journal_title：Current opinion in allergy and clinical immunology

authors： Platt M,Metson R,Stankovic K

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review updates current findings on long-term clinical and immunological outcomes after cessation of allergen immunotherapy for allergic respiratory disease. RECENT FINDINGS:Recent studies have shown that allergen immunotherapy has sustained disease-modifying effects that persist for years...

journal_title：Current opinion in allergy and clinical immunology

authors： Eifan AO,Shamji MH,Durham SR

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Dental professionals and their physicians frequently do not recognize, accurately diagnose or appropriately manage occupational allergies. Dental allergen identification, diagnostics and practical avoidance strategies are summarized in this review. RECENT FINDINGS:Methacrylates, natural rubber latex ...

journal_title：Current opinion in allergy and clinical immunology

authors： Hamann CP,Rodgers PA,Sullivan KM

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the diverse clinical manifestations of IgE-mediated allergy to ingested wheat and summarizes recent advances in characterization of clinically significant allergens and diagnostic workup. RECENT FINDINGS:Recent population-based studies have shown the prevalence of wheat allergy ...

journal_title：Current opinion in allergy and clinical immunology

authors： Inomata N

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The frequency of hospitalization for anaphylaxis has increased over the last 20 years across Europe, Australia, and North America, particularly, for food and medication triggers. Adolescents show the highest risk for morbidity and fatality from food-induced anaphylaxis, yet there is little high-qualit...

journal_title：Current opinion in allergy and clinical immunology

authors： Comberiati P,Spahn J,Peroni DG

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Anaphylactic cardiovascular collapse can be resistant to treatment with epinephrine (adrenaline) and, in some cases, diagnostic uncertainty compromises follow-up care. The purpose of this review is to examine recent studies relevant to the management and diagnosis of this condition. RECENT FINDINGS:N...

journal_title：Current opinion in allergy and clinical immunology

authors： Brown SG

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to evaluate the effect of histamine on various receptors in the conjunctiva. A Medline search from 1980 was performed on the histamine receptor subtypes H1, H2 and H3 in the human conjunctiva. RECENT FINDINGS:In the conjunctiva, histamine has been shown to induce various...

journal_title：Current opinion in allergy and clinical immunology

authors： Bielory L,Ghafoor S

更新日期：2005-10-01 00:00:00